Dynamic antibody-binding properties in the pathogenesis of HIT

Blood

Volumn 120, Issue 5, 2012, Pages 1137-1142

  Sachais, Bruce S ^a   Litvinov, Rustem I ^a   Yarovoi, Serge V ^a   Rauova, Lubica ^b,c   Hinds, Jillian L ^a   Rux, Ann H ^a   Arepally, Gowthami M ^d   Poncz, Mortimer ^b   Cuker, Adam ^a,e   Weisel, John W ^a   Cines, Douglas B ^a,e  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c NATIONAL INSTITUTE OF RHEUMATIC DISEASES   (Slovakia)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; EPITOPE; GLUTAMIC ACID; HEPARIN; HEPARIN BINDING PROTEIN; HEPARIN PLATELET FACTOR 4 ANTIBODY; LYSINE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY KKO; MONOCLONAL ANTIBODY RTO; TETRAMER; THROMBOCYTE FACTOR 4; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANTIBODY AFFINITY; ANTIGEN SPECIFICITY; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DIMERIZATION; DRUG BINDING; ENZYME LINKED IMMUNOSORBENT ASSAY; GROWTH INHIBITION; HEPARIN INDUCED THROMBOCYTOPENIA; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR DYNAMICS; MOLECULE; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; THROMBOCYTE ACTIVATION; THROMBOCYTE COUNT; THROMBOCYTOPENIA;

EID: 84864562115     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-01-407262     Document Type: Article

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