Optimisation of exposure conditions for in vitro radiobiology experiments

Australasian Physical and Engineering Sciences in Medicine

Volumn 35, Issue 2, 2012, Pages 151-157

  Mackonis, Elizabeth Claridge ^a   Suchowerska, Natalka ^a,b   Naseri, Pourandokht ^b   McKenzie, David R ^b  

^a ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Dosimetry; In vitro; Irradiation; MV; Radiobiology

Indexed keywords

CELL LAYERS; CLONOGENIC ASSAYS; EXPOSURE CONDITIONS; EXPOSURE ENVIRONMENT; IN-VITRO; MODULATED FIELD; MV; OPTIMISATIONS; PHANTOM MATERIALS; PHOTON BEAMS; RADIOBIOLOGICAL STUDY; RADIOBIOLOGY; WATER EQUIVALENT; WELL PLATES;

BIOPHYSICS; CELL CULTURE; CELLS; DOSIMETRY; IRRADIATION; RADIOACTIVITY;

BOTTLES;

ARTICLE; BIOASSAY; COMPARATIVE STUDY; CULTURE TECHNIQUE; EQUIPMENT; EQUIPMENT DESIGN; INSTRUMENTATION; RADIATION DOSE; RADIATION SCATTERING; RADIOBIOLOGY; RADIOMETRY;

BIOLOGICAL ASSAY; CELL CULTURE TECHNIQUES; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; RADIATION DOSAGE; RADIOBIOLOGY; RADIOMETRY; SCATTERING, RADIATION;

EID: 84864559022     PISSN: 01589938     EISSN: None     Source Type: Journal    
DOI: 10.1007/s13246-012-0132-6     Document Type: Article

References (22)

1. Sjostedt S, Bezak E (2010) Non-targeted effects of ionising radiation and radiotherapy. Australas Phys Eng Sci Med 33: 219-231
2. Butterworth KT, McGarry CK, Trainor C, Sullivan JM, Hounsell AR, Prise KM (2011) Out-of-field cell survival following exposure to intensity-modulated radiation fields. Int J Radiat Oncol Biol Phys 79:1516-1522
3. Claridge Mackonis E, Suchowerska N, Zhang M, Ebert M, McKenzie DR, Jackson M (2007) Cellular response to modulated radiation field. Phys Med Biol 52:5469-5482
4. Kellerer AM, Roos H (2005) Are all photon radiation similar in larger absorbers?-A comparison of electron spectra. Radiat Prot Dosim 113:245-250
5. Pattison JE, Hugtenburg RP, Charles MW, Beddoe AH (2001) Experimental simulation of A-bomb gamma ray spectra for radiobiology studies. Radiat Prot Dosim 92:125-136
6. Harder D, Petoussi-Henß N, Regulla D, Zankl M, Dietze G (2004) Radiat Prot Dosim 109:291-295
7. Altman MB, Vesper BJ, Smith BD, Stinauer MA, Pelizzari CA, Aydogan B, Reft CS, Radosevich JA, Chmura SJ, Roeske JC (2009) Characterization of a novel phantom for three-dimensional in vitro cell experiments. Phys Med Biol 54:N75-N82
8. Moiseenko V, Duzenli C (2007) In vitro study of cell survival following dynamic MLC intensity-modulated radiation therapy dose delivery. Med Phys 34:1514-1520
9. Sterzing F, Münter MW, Schäfer M, Haering P, Rhein B, Thilmann C, Debus J (2005) Radiobiological investigation of doserate effects in intensity-modulated radiation therapy. Strahlenther Onkol 181:42-48
10. McGarry CK, Butterworth KT, Trainor C, O'Sullivan JM, Prise KM, Hounsell AP (2011) Temporal characterization and in vitro comparison of cell survival following the delivery of 3D-conformal, intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT). Phys Med Biol 56:2445-2457
11. Seymour CB, Mothersill C (1989) Lethal mutations, the survival curve shoulder and split-dose recovery. Int J Radiat Biol 56:999-1010
12. Keall P, Chang M, Benedict S, Thames H, Vedam SS, Lin P-S (2008) Investigating the temporal effects of respiratory-gated and intensity-modulated radiotherapy treatments delivery on in vitro survival: an experimental and theoretical study. Int J Radiat Oncol Biol Phys 71:1547-1552
13. Ling CC, Li WX, Anderson LL (1995) The relative biological effectiveness of I-125 and Pd-103. Int J Radiat Oncol Biol Phys 32: 373-378
14. Mu X, Löfroth P-O, Karlsson M, Zackrisson B (2003) The effect of fraction time in intensity modulated radiotherapy: theoretical and experimental evaluation of an optimisation problem. Radiother Oncol 68:181-187
15. Suchowerska N, Ebert MA, Zhang M, Jackson M (2005) In vitro response of tumour cells to non-uniform irradiation. Phys Med Biol 50:3041-3051
16. Bromley R, Davey R, Oliver L, Harvie R, Baldock C (2006) A preliminary investigation of cell growth after irradiation using a modulated X-ray intensity pattern. Phys Med Biol 51:3639-3651
17. Bewes JM, Suchowerska N, Jackson M, Zhang M, McKenzie DR (2008) The radiobiological effect of intra-fraction dose-rate modulation in intensity modulated radiation therapy (IMRT). Phys Med Biol 56:3567-3578
18. Gow MD, Seymour CB, Byun S-H, Mothersill CE (2008) Effect of dose rate on the radiation-induced bystander response. Phys Med Biol 53:119-132
19. Xing L, Sun X, Deng X, Kotedia K, Urano M, Koutcher JA, Ling CC, Li GC (2009) Expression of the bifunctional suicide gene CDUPRT increases radiosensitization and bystander effect of 5-FC in prostate cancer cells. Radiother Oncol 92:345-352
20. Hehlgans S, Lange I, Eke I, Cordes N (2009) 3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226. Radiother Oncol 92:371-378
21. International Atomic Energy Agency (2000) absorbed dose determination in external beam radiotherapy. Technical report series no 398, IAEA, Vienna. pp 210-214
22. Lui L, Prasad SC, Bassano DA (2003) Evaluation of two waterequivalent phantom materials for output calibration of photon and electron beams. Med Dosim 28(4):267-269