-
1
-
-
33646568784
-
Patterns of cancer incidence, mortality, and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world
-
DOI 10.1200/JCO.2005.05.2308
-
Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 2006;24:2137-50. (Pubitemid 46655601)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.14
, pp. 2137-2150
-
-
Kamangar, F.1
Dores, G.M.2
Anderson, W.F.3
-
3
-
-
78649724338
-
Human epidermal growth factor receptor 2 (HER2) in gastric cancer: A new therapeutic target
-
De Vita F, Giuliani F, Silvestris N, et al. Human epidermal growth factor receptor 2 (HER2) in gastric cancer: a new therapeutic target. Cancer Treat Rev 2010;36(Suppl 3):S11-15.
-
(2010)
Cancer Treat Rev
, vol.36
, Issue.SUPPL. 3
-
-
De Vita, F.1
Giuliani, F.2
Silvestris, N.3
-
4
-
-
77956262693
-
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
-
Bang YJ, Van Cutsem E, Feyereislova A, et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet 2010;376:687-97.
-
(2010)
Lancet
, vol.376
, pp. 687-697
-
-
Bang, Y.J.1
Van Cutsem, E.2
Feyereislova, A.3
-
5
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
DOI 10.1126/science.275.5308.1943
-
Li J, Yen C, Liaw D, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997;275:1943-7. (Pubitemid 27148818)
-
(1997)
Science
, vol.275
, Issue.5308
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.I.6
Puc, J.7
Miliaresis, C.8
Rodgers, L.9
McCombie, R.10
Bigner, S.H.11
Giovanella, B.C.12
Ittmann, M.13
Tycko, B.14
Hibshoosh, H.15
Wigler, M.H.16
Parsons, R.17
-
6
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
DOI 10.1074/jbc.273.22.13375
-
Maehama T, Dixon JE. The tumour suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 1998;273:13375-8. (Pubitemid 28268370)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.22
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
7
-
-
34547838420
-
PTEN, more than the AKT pathway
-
DOI 10.1093/carcin/bgm052
-
Blanco-Aparicio C, Renner O, Leal JF, et al. PTEN, more than the AKT pathway. Carcinogenesis 2007;28:1379-86. (Pubitemid 47243536)
-
(2007)
Carcinogenesis
, vol.28
, Issue.7
, pp. 1379-1386
-
-
Blanco-Aparicio, C.1
Renner, O.2
Leal, J.F.M.3
Carnero, A.4
-
8
-
-
77949452524
-
The PKB/AKT pathway in cancer
-
Carnero A. The PKB/AKT pathway in cancer. Curr Pharm Des 2010;16:34-44.
-
(2010)
Curr Pharm des
, vol.16
, pp. 34-44
-
-
Carnero, A.1
-
9
-
-
77957352037
-
PTEN, PIK3CA, p-AKT, and p-p70S6K status: Association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer
-
Esteva FJ, Guo H, Zhang S, et al. PTEN, PIK3CA, p-AKT, and p-p70S6K status: association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer. Am J Pathol 2010;177:1647-56.
-
(2010)
Am J Pathol
, vol.177
, pp. 1647-1656
-
-
Esteva, F.J.1
Guo, H.2
Zhang, S.3
-
12
-
-
44249092320
-
Assessment of a HER2 scoring system for gastric cancer: Results from a validation study
-
DOI 10.1111/j.1365-2559.2008.03028.x
-
Hofmann M, Stoss O, Shi D, et al. Assessment of a HER2 scoring system for gastric cancer: results from a validation study. Histopathology 2008;52:797-805. (Pubitemid 351724903)
-
(2008)
Histopathology
, vol.52
, Issue.7
, pp. 797-805
-
-
Hofmann, M.1
Stoss, O.2
Shi, D.3
Buttner, R.4
Van De, V.M.5
Kim, W.6
Ochiai, A.7
Ruschoff, J.8
Henkel, T.9
-
13
-
-
33646923255
-
Impact of loss of heterozygosity of encoding phosphate and tensin homolog on the prognosis of gastric cancer
-
DOI 10.1111/j.1440-1746.2005.04028.x
-
Oki E, Kakeji Y, Baba H, et al. Impact of loss of heterozygosity of encoding phosphate and tensin homolog on the prognosis of gastric cancer. J Gastroenterol Hepatol 2006;21:814-18. (Pubitemid 43793276)
-
(2006)
Journal of Gastroenterology and Hepatology
, vol.21
, Issue.5
, pp. 814-818
-
-
Oki, E.1
Kakeji, Y.2
Baba, H.3
Tokunaga, E.4
Nakamura, T.5
Ueda, N.6
Futatsugi, M.7
Yamamoto, M.8
Ikebe, M.9
Maehara, Y.10
-
14
-
-
26444503696
-
AKT phosphorylation associates with LOH of PTEN and leads to chemoresistance for gastric cancer
-
DOI 10.1002/ijc.21170
-
Oki E, Baba H, Tokunaga E, et al. Akt phosphorylation associates with LOH of PTEN and leads to chemoresistance for gastric cancer. Int J Cancer 2005;117:376-80. (Pubitemid 41429560)
-
(2005)
International Journal of Cancer
, vol.117
, Issue.3
, pp. 376-380
-
-
Oki, E.1
Baba, H.2
Tokunaga, E.3
Nakamura, T.4
Ueda, N.5
Futatsugi, M.6
Mashino, K.7
Yamamoto, M.8
Ikebe, M.9
Kakeji, Y.10
Maehara, Y.11
-
15
-
-
12344273281
-
Loss of heterozygosity on 10q23.3 and mutation of tumor suppressor gene PTEN in gastric cancer and precancerous lesions
-
Li YL, Tian Z, Wu DY, et al. Loss of heterozygosity on 10q23.3 and mutation of tumor suppressor gene PTEN in gastric cancer and precancerous lesions. World J Gastroenterol 2005;11:285-8. (Pubitemid 40125221)
-
(2005)
World Journal of Gastroenterology
, vol.11
, Issue.2
, pp. 285-288
-
-
Li, Y.-L.1
Tian, Z.2
Wu, D.-Y.3
Fu, B.-Y.4
Xin, Y.5
-
16
-
-
0037431435
-
Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma
-
DOI 10.1002/ijc.10962
-
Byun DS, Cho K, Ryu BK, et al. Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma. Int J Cancer 2003;104:318-27. (Pubitemid 36249814)
-
(2003)
International Journal of Cancer
, vol.104
, Issue.3
, pp. 318-327
-
-
Byun, D.-S.1
Cho, K.2
Ryu, B.-K.3
Lee, M.-G.4
Park, J.-I.5
Chae, K.-S.6
Kim, H.-J.7
Chi, S.-G.8
-
17
-
-
0033118646
-
Mutation analysis of the PTEN/MMAC1 gene in cancers of the digestive tract
-
Chang JG, Chen YJ, Perng LI, et al. Mutation analysis of the PTEN/MMAC1 gene in cancers of the digestive tract. Eur J Cancer 1999;35:647-51.
-
(1999)
Eur J Cancer
, vol.35
, pp. 647-651
-
-
Chang, J.G.1
Chen, Y.J.2
Perng, L.I.3
-
18
-
-
0033912369
-
Relationship between chromosomal instability and intratumoral regional DNA ploidy heterogeneity in primary gastric cancers
-
Furuya T, Uchiyama T, Murakami T, et al. Relationship between chromosomal instability and intratumoral regional DNA ploidy heterogeneity in primary gastric cancers. Clin Cancer Res 2000;6:2815-20. (Pubitemid 30482122)
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.7
, pp. 2815-2820
-
-
Furuya, T.1
Uchiyama, T.2
Murakami, T.3
Adachi, A.4
Kawauchi, S.5
Oga, A.6
Hirano, T.7
Sasaki, K.8
-
19
-
-
4243058132
-
DNA-ploidy in advanced gastric carcinoma is less heterogeneous than in early gastric cancer
-
Osterheld MC, Caron L, Demierre M, et al. DNA-ploidy in advanced gastric carcinoma is less heterogeneous than in early gastric cancer. Cell Oncol 2004;26:21-9. (Pubitemid 39108240)
-
(2004)
Cellular Oncology
, vol.26
, Issue.1-2
, pp. 21-29
-
-
Osterheld, M.-C.1
Caron, L.2
Demierre, M.3
Laurini, R.4
Bosman, F.T.5
-
20
-
-
77952975814
-
Mutation analysis of tumor suppressor gene PTEN in patients with gastric carcinomas and its impact on PI3K/AKT pathway
-
Wen YG, Wang Q, Zhou CZ, et al. Mutation analysis of tumor suppressor gene PTEN in patients with gastric carcinomas and its impact on PI3K/AKT pathway. Oncol Rep 2010;24:89-95.
-
(2010)
Oncol Rep
, vol.24
, pp. 89-95
-
-
Wen, Y.G.1
Wang, Q.2
Zhou, C.Z.3
-
21
-
-
54349106979
-
PCR-SSCP-DNA sequencing method in detecting PTEN gene mutation and its significance in human gastric cancer
-
Guo CY, Xu XF, Wu JY, et al. PCR-SSCP-DNA sequencing method in detecting PTEN gene mutation and its significance in human gastric cancer. World J Gastroenterol 2008;14:3804-11.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 3804-3811
-
-
Guo, C.Y.1
Xu, X.F.2
Wu, J.Y.3
-
22
-
-
27744437224
-
Molecular study of the tumour suppressor gene PTEN in gastric adenocarcinoma in Brazil
-
DOI 10.1007/s10238-005-0077-0
-
Lima EM, Araújo JJ, Harada ML, et al. Molecular study of the tumour suppressor gene PTEN in gastric adenocarcinoma in Brazil. Clin Exp Med 2005;5:129-32. (Pubitemid 41597273)
-
(2005)
Clinical and Experimental Medicine
, vol.5
, Issue.3
, pp. 129-132
-
-
Lima, E.M.1
Araujo, J.J.2
Harada, M.L.3
Assumpcao, P.P.4
Burbano, R.R.5
Casartelli, C.6
-
23
-
-
0038459116
-
Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in advanced gastric carcinomas
-
Wang JY, Huang TJ, Chen FM, et al. Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in advanced gastric carcinomas. Virchows Arch 2003;442:437-43.
-
(2003)
Virchows Arch
, vol.442
, pp. 437-443
-
-
Wang, J.Y.1
Huang, T.J.2
Chen, F.M.3
-
24
-
-
18244406326
-
Analysis of genetic and epigenetic alterations of the PTEN gene in gastric cancer
-
DOI 10.1007/s004280100499
-
Sato K, Tamura G, Tsuchiya T, et al. Analysis of genetic and epigenetic alterations of the PTEN gene in gastric cancer. Virchows Arch 2002;440:160-5. (Pubitemid 34169853)
-
(2002)
Virchows Archiv
, vol.440
, Issue.2
, pp. 160-165
-
-
Sato, K.1
Tamura, G.2
Tsuchiya, T.3
Endoh, Y.4
Sakata, K.5
Motoyama, T.6
Usuba, O.7
Kimura, W.8
Terashima, M.9
Nishizuka, S.10
Zou, T.11
Meltzer, S.J.12
-
25
-
-
0036127525
-
Promoter methylation and silencing of PTEN in gastric carcinoma
-
Kang YH, Lee HS, Kim WH. Promoter methylation and silencing of PTEN in gastric carcinoma. Lab Invest 2002;82:285-91.
-
(2002)
Lab Invest
, vol.82
, pp. 285-291
-
-
Kang, Y.H.1
Lee, H.S.2
Kim, W.H.3
-
26
-
-
77955409200
-
Constitutive activation of glycogen synthase kinase-3beta correlates with better prognosis and cyclin-dependent kinase inhibitors in human gastric cancer
-
Cho YJ, Kim JH, Yoon J, et al. Constitutive activation of glycogen synthase kinase-3beta correlates with better prognosis and cyclin-dependent kinase inhibitors in human gastric cancer. BMC Gastroenterol 2010;10:91.
-
(2010)
BMC Gastroenterol
, vol.10
, pp. 91
-
-
Cho, Y.J.1
Kim, J.H.2
Yoon, J.3
-
27
-
-
25144449918
-
Prognostic significance of CD24 expression in gastric carcinoma
-
Darwish NS, Kim MA, Chang MS, et al. Prognostic significance of CD24 expression in gastric carcinoma. Cancer Res Treat 2004;36:298-302.
-
(2004)
Cancer Res Treat
, vol.36
, pp. 298-302
-
-
Darwish, N.S.1
Kim, M.A.2
Chang, M.S.3
-
28
-
-
0037987700
-
Tumour suppressor gene expression correlates with gastric cancer prognosis
-
DOI 10.1002/path.1288
-
Lee HS, Lee HK, Kim HS, et al. Tumour suppressor gene expression correlates with gastric cancer prognosis. J Pathol 2003;200:39-46. (Pubitemid 36592634)
-
(2003)
Journal of Pathology
, vol.200
, Issue.1
, pp. 39-46
-
-
Lee, H.S.1
Lee, H.K.2
Kim, H.S.3
Yang, H.-K.4
Kim, W.H.5
-
29
-
-
37549055803
-
Homeoprotein Cdx2 and nuclear PTEN expression profiles are related to gastric cancer prognosis
-
Bai Z, Ye Y, Chen D, et al. Homeoprotein Cdx2 and nuclear PTEN expression profiles are related to gastric cancer prognosis. APMIS 2007;115:1383-90.
-
(2007)
APMIS
, vol.115
, pp. 1383-1390
-
-
Bai, Z.1
Ye, Y.2
Chen, D.3
-
30
-
-
33645102673
-
Significance of Survivin and PTEN expression in full lymph node-examined gastric cancer
-
Deng H, Wu RL, Zhou HY, et al. Significance of Survivin and PTEN expression in full lymph node-examined gastric cancer. World J Gastroenterol 2006;12:1013-17.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 1013-1017
-
-
Deng, H.1
Wu, R.L.2
Zhou, H.Y.3
-
31
-
-
33947378317
-
Pathobiological characteristics of intestinal and diffuse-type gastric carcinoma in Japan: An immunostaining study on the tissue microarray
-
DOI 10.1136/jcp.2006.038778
-
Zheng H, Takahashi H, Murai Y, et al. Pathobiological characteristics of intestinal and diffuse-type gastric carcinoma in Japan: an immunostaining study on the tissue microarray. J Clin Pathol 2007;60:273-7. (Pubitemid 46447742)
-
(2007)
Journal of Clinical Pathology
, vol.60
, Issue.3
, pp. 273-277
-
-
Zheng, H.1
Takahashi, H.2
Murai, Y.3
Cui, Z.4
Nomoto, K.5
Miwa, S.6
Tsuneyama, K.7
Takano, Y.8
-
32
-
-
32844474579
-
HER2 overexpression with loss of PTEN expression in gastric carcinomas
-
Im SA, Lee KE, Nam E, et al. Potential prognostic significance of p185(HER2) overexpression with loss of PTEN expression in gastric carcinomas. Tumori 2005;91:513-21. (Pubitemid 43251123)
-
(2005)
Tumori
, vol.91
, Issue.6
, pp. 513-521
-
-
Im, S.-A.1
Lee, K.E.2
Nam, E.3
Kim, D.Y.4
Lee, J.-H.5
Han, H.-S.6
Seoh, J.-Y.7
Park, H.-Y.8
Cho, M.-S.9
Han, W.S.10
Lee, S.N.11
-
33
-
-
7044235217
-
Inactivation of PTEN is associated with increased angiogenesis and VEGF overexpression in gastric cancer
-
Zhou YJ, Xiong YX, Wu XT, et al. Inactivation of PTEN is associated with increased angiogenesis and VEGF overexpression in gastric cancer. World J Gastroenterol 2004;10:3225-9.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 3225-3229
-
-
Zhou, Y.J.1
Xiong, Y.X.2
Wu, X.T.3
-
34
-
-
33845991111
-
NEDD4-1 Is a Proto-Oncogenic Ubiquitin Ligase for PTEN
-
DOI 10.1016/j.cell.2006.11.039, PII S0092867406015480
-
Wang X, Trotman LC, Koppie T, et al. NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN. Cell 2007;128:129-39. (Pubitemid 46048884)
-
(2007)
Cell
, vol.128
, Issue.1
, pp. 129-139
-
-
Wang, X.1
Trotman, L.C.2
Koppie, T.3
Alimonti, A.4
Chen, Z.5
Gao, Z.6
Wang, J.7
Erdjument-Bromage, H.8
Tempst, P.9
Cordon-Cardo, C.10
Pandolfi, P.P.11
Jiang, X.12
-
35
-
-
34548045045
-
2-terminal kinase activation and nuclear factor-kappaB inhibition
-
DOI 10.1158/0008-5472.CAN-07-0187
-
Wang Q, Zhou Y, Wang X, et al. Regulation of PTEN expression in intestinal epithelial cells by c-Jun NH2-terminal kinase activation and nuclear factor-kappaB inhibition. Cancer Res 2007;67:7773-81. (Pubitemid 47281371)
-
(2007)
Cancer Research
, vol.67
, Issue.16
, pp. 7773-7781
-
-
Wang, Q.1
Zhou, Y.2
Wang, X.3
Chung, D.H.4
Evers, B.M.5
-
36
-
-
66149158167
-
Post-transcriptional and post-translational regulation of PTEN by transforming growth factor-beta1
-
Yang Y, Zhou F, Fang Z, et al. Post-transcriptional and post-translational regulation of PTEN by transforming growth factor-beta1. J Cell Biochem 2009;106:1102-12.
-
(2009)
J Cell Biochem
, vol.106
, pp. 1102-1112
-
-
Yang, Y.1
Zhou, F.2
Fang, Z.3
-
37
-
-
67650917081
-
PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer
-
Sircar K, Yoshimoto M, Monzon FA, et al. PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer. J Pathol 2009;218:505-13.
-
(2009)
J Pathol
, vol.218
, pp. 505-513
-
-
Sircar, K.1
Yoshimoto, M.2
Monzon, F.A.3
-
38
-
-
30544449647
-
Clinical utility of fluorescence in situ hybridization (FISH) in nonbrainstem glioblastomas of childhood
-
DOI 10.1038/modpathol.3800415, PII 3800415
-
Korshunov A, Sycheva R, Gorelyshev S, et al. Clinical utility of fluorescence in situ hybridization (FISH) in nonbrainstem glioblastomas of childhood. Mod Pathol 2005;18:1258-63. (Pubitemid 43079926)
-
(2005)
Modern Pathology
, vol.18
, Issue.9
, pp. 1258-1263
-
-
Korshunov, A.1
Sycheva, R.2
Gorelyshev, S.3
Golanov, A.4
-
39
-
-
65249086248
-
Combined PTEN and p27kip1 protein expression patterns are associated with obesity and prognosis in endometrial carcinomas
-
Dellas A, Jundt G, Sartorius G, et al. Combined PTEN and p27kip1 protein expression patterns are associated with obesity and prognosis in endometrial carcinomas. Clin Cancer Res 2009;15:2456-62.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2456-2462
-
-
Dellas, A.1
Jundt, G.2
Sartorius, G.3
-
40
-
-
5144226211
-
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
-
DOI 10.1016/j.ccr.2004.06.022, PII S1535610804002107
-
Nagata Y, Lan KH, Zhou X, et al. PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 2004;6:117-27. (Pubitemid 39485684)
-
(2004)
Cancer Cell
, vol.6
, Issue.2
, pp. 117-127
-
-
Nagata, Y.1
Lan, K.-H.2
Zhou, X.3
Tan, M.4
Esteva, F.J.5
Sahin, A.A.6
Klos, K.S.7
Li, P.8
Monia, B.P.9
Nguyen, N.T.10
Hortobagyi, G.N.11
Hung, M.-C.12
Yu, D.13
-
41
-
-
79952987662
-
Differences of immunophenotypic markers and signaling molecules between adenocarcinomas of gastric cardia and distal stomach
-
Xue L, Zhang X, Li Y, et al. Differences of immunophenotypic markers and signaling molecules between adenocarcinomas of gastric cardia and distal stomach. Hum Pathol 2011;42:594-601.
-
(2011)
Hum Pathol
, vol.42
, pp. 594-601
-
-
Xue, L.1
Zhang, X.2
Li, Y.3
-
42
-
-
79951497419
-
The genomic complexity of primary human prostate cancer
-
Berger MF, Lawrence MS, Demichelis F, et al. The genomic complexity of primary human prostate cancer. Nature 2011;470:214-20.
-
(2011)
Nature
, vol.470
, pp. 214-220
-
-
Berger, M.F.1
Lawrence, M.S.2
Demichelis, F.3
|