Targeted delivery of nerve growth factor via encapsulated cell biodelivery in Alzheimer disease: A technology platform for restorative neurosurgery - Clinical article

Journal of Neurosurgery

Volumn 117, Issue 2, 2012, Pages 340-347

  Wahlberg, Lars U ^a,b   Lind, Göran ^a   Almqvist, Per M ^a,b   Kusk, Philip ^b   Tornøe, Jens ^b   Juliusson, Bengt ^b   Söderman, Michael ^a   Selldén, Eva ^a   Seiger, Åke ^a   Eriksdotter Jönhagen, Maria ^a   Linderoth, Bengt ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b NsGene AS   (Denmark)

Author keywords

Alzheimer disease; Cholinergic forebrain; Clinical trial; Encapsulated cell; Functional neurosurgery; Nerve growth factor; Restorative neurosurgery; Stereotaxy

Indexed keywords

NERVE GROWTH FACTOR;

ALZHEIMER DISEASE; ARTICLE; CELL ENCAPSULATION; CELL LINE; CLINICAL ARTICLE; DIAGONAL BAND OF BROCA; DRUG DELIVERY SYSTEM; DRUG TARGETING; ENCAPSULATED CELL BIODELIVERY; HOLLOW FIBER MEMBRANE; HUMAN; HUMAN CELL; IMPLANT; MEYNERT BASAL NUCLEUS; NEUROSURGERY; NGC 0295 CELL LINE; OPEN STUDY; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; SAFETY; STEREOTAXIC SURGERY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BASAL NUCLEUS OF MEYNERT; CAPSULES; CELL LINE; CHOLINERGIC FIBERS; COHORT STUDIES; DIAGONAL BAND OF BROCA; DRUG DELIVERY SYSTEMS; DRUG IMPLANTS; DRUG TOXICITY; EQUIPMENT DESIGN; FEMALE; GENETIC ENGINEERING; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NERVE GROWTH FACTOR; NEUROSURGICAL PROCEDURES; POSTOPERATIVE COMPLICATIONS; PROSENCEPHALON; STEREOTAXIC TECHNIQUES; SUTURE ANCHORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84864530993     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2012.2.JNS11714     Document Type: Article

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