Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease

Human Molecular Genetics

Volumn 21, Issue 15, 2012, Pages 3397-3407

  Natoli, Thomas A ^a   Husson, Hervé ^a   Rogers, Kelly A ^a   Smith, Laurie A ^a   Wang, Bing ^a   Budman, Yeva ^a   Bukanov, Nikolay O ^a   Ledbetter, Steven R ^a   Klinger, Katherine W ^a   Leonard, John P ^b   Ibraghimov beskrovnaya, Oxana ^a  

^a SANOFI   (France)

^b GENZYME CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GANGLIOSIDE GM3; GANGLIOSIDE GM3 SYNTHASE; GLUCOSYLCERAMIDE; GLYCOSPHINGOLIPID; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PROTEIN KINASE B; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE 1; SYNTHETASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CYCLE; CONTROLLED STUDY; DISEASE COURSE; ENZYME INHIBITION; GENE LOSS; GENE MUTATION; GENE OVEREXPRESSION; KIDNEY POLYCYSTIC DISEASE; MOUSE; NEPHRONOPHTHISIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; DISEASE MODELS, ANIMAL; GLUCOSYLCERAMIDES; GLYCOSPHINGOLIPIDS; MICE; ONCOGENE PROTEIN V-AKT; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); POLYCYSTIC KIDNEY DISEASES; SIALYLTRANSFERASES; SPHINGOSINE; TOR SERINE-THREONINE KINASES;

MURINAE; MUS;

EID: 84864497856     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/dds172     Document Type: Article

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