Regulation of actin cytoskeleton by Rap1 binding to RacGEF1

Molecules and Cells

Volumn 34, Issue 1, 2012, Pages 71-76

  Mun, Hyemin ^a   Jeon, Taeck J ^a  

^a Chosun University   (South Korea)

Author keywords

actin cytoskeleton; chemotaxis; Dictyostelium; RacGEF1; Rap1

Indexed keywords

CHEMOATTRACTANT; F ACTIN; GREEN FLUORESCENT PROTEIN; KHELLIN; PROTEIN KINASE B; RAC PROTEIN; RAP1 PROTEIN; RAS PROTEIN;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ARTICLE; BINDING ASSAY; CHEMOTAXIS; CONTROLLED STUDY; DICTYOSTELIUM; IN VITRO STUDY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REPORTER GENE; SIGNAL TRANSDUCTION;

ACTIN CYTOSKELETON; CHEMOTACTIC FACTORS; CHEMOTAXIS; DICTYOSTELIUM; ENZYME ACTIVATION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; KINETICS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN BINDING; PROTEIN TRANSPORT; PROTOZOAN PROTEINS; RAP1 GTP-BINDING PROTEINS; RAS PROTEINS; SIGNAL TRANSDUCTION;

DICTYOSTELIUM;

EID: 84864484625     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.1007/s10059-012-0097-z     Document Type: Article

References (32)

1. W.T. Arthur L.A. Quilliam J.A. Cooper 2004 Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors J. Cell Biol. 167 111 122 15479739 10.1083/jcb.200404068 1:CAS:528:DC%2BD2cXosVOiu7k%3D (Pubitemid 39363419)
2. A. Bagorda C.A. Parent 2008 Eukaryotic chemotaxis at a glance J. Cell Sci. 121 2621 2624 18685153 10.1242/jcs.018077 1:CAS:528:DC%2BD1cXhtFKhu73O
3. P. Bolourani G.B. Spiegelman G. Weeks 2006 Delineation of the roles played by RasG and RasC in cAMP-dependent signal transduction during the early development of Dictyostelium discoideum Mol. Biol. Cell 17 4543 4550 16885420 10.1091/mbc.E05-11-1019 1:CAS:528:DC%2BD28XhtFSjtL7I (Pubitemid 44522069)
4. P. Bolourani G.B. Spiegelman G. Weeks 2008 Rap1 activation in response to cAMP occurs downstream of ras activation during Dictyostelium aggregation J. Biol. Chem. 283 10232 10240 18180289 10.1074/jbc.M707459200 1:CAS:528: DC%2BD1cXksFags74%3D
5. J.L. Bos 2005 Linking Rap to cell adhesion Curr. Opin. Cell Biol. 17 123 128 15780587 10.1016/j.ceb.2005.02.009 1:CAS:528:DC%2BD2MXisVCqtLk%3D (Pubitemid 40380934)
6. I. Cha S.H. Lee T.J. Jeon 2010 Chemoattractant-mediated Rap1 activation requires GPCR/G proteins Mol. Cells 30 563 567 21103944 10.1007/s10059-010-0153- 5 1:CAS:528:DC%2BC3MXit1Khu7c%3D
7. L. Chen M. Iijima M. Tang M.A. Landree Y.E. Huang Y. Xiong P.A. Iglesias P.N. Devreotes 2007 PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis Dev. Cell 12 603 614 17419997 10.1016/j.devcel.2007.03.005 1:CAS:528:DC%2BD2sXksVOhsLk%3D (Pubitemid 46523645)
8. 2+-mediated activation of Rap1 in human platelets EMBO J. 16 252 259 9029146 10.1093/emboj/16.2.252 1:CAS:528:DyaK2sXpvVSqsA%3D%3D (Pubitemid 27049383)
9. S. Funamoto K. Milan R. Meili R.A. Firtel 2001 Role of phosphatidylinositol 3′ kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium J. Cell Biol. 153 795 810 11352940 10.1083/jcb.153.4.795 1:CAS:528:DC%2BD3MXjs1Wgsbw%3D (Pubitemid 34286111)
10. S. Funamoto R. Meili S. Lee L. Parry R.A. Firtel 2002 Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis Cell 109 611 623 12062104 10.1016/S0092-8674(02)00755-9 1:CAS:528:DC%2BD38XksVGgs78%3D (Pubitemid 34628724)
11. A. Gerard A.E. Mertens R.A. van der Kammen J.G. Collard 2007 The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization J. Cell Biol. 176 863 875 17353362 10.1083/jcb.200608161 1:CAS:528: DC%2BD2sXjt1GitLc%3D (Pubitemid 46425546)
12. G. Gerisch R. Albrecht C. Heizer S. Hodgkinson M. Maniak 1995 Chemoattractant-controlled accumulation of coronin at the leading edge of Dictyostelium cells monitored using a green fluorescent protein-coronin fusion protein Curr. Biol. 5 1280 1285 8574585 10.1016/S0960-9822(95)00254-5 1:CAS:528:DyaK2MXptlWit7s%3D (Pubitemid 3000037)
13. N. Ibarra A. Pollitt R.H. Insall 2005 Regulation of actin assembly by SCAR/WAVE proteins Biochem. Soc. Trans. 33 1243 1246 16246088 10.1042/BST20051243 1:CAS:528:DC%2BD2MXhtFCqsL7F (Pubitemid 41779657)
14. T.J. Jeon D.J. Lee S. Merlot G. Weeks R.A. Firtel 2007 Rap1 controls cell adhesion and cell motility through the regulation of myosin II J. Cell Biol. 176 1021 1033 17371831 10.1083/jcb.200607072 1:CAS:528:DC%2BD2sXjvVSnsbk%3D (Pubitemid 46506974)
15. T.J. Jeon D.J. Lee S. Lee G. Weeks R.A. Firtel 2007 Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells J. Cell Biol. 179 833 843 18039932 10.1083/jcb.200705068 1:CAS:528: DC%2BD2sXhsVeisLfM (Pubitemid 350223482)
16. T.J. Jeon S. Lee G. Weeks R.A. Firtel 2009 Regulation of Dictyostelium morphogenesis by RapGAP3 Dev. Biol. 328 210 220 19284976 10.1016/j.ydbio.2009. 01.016 1:CAS:528:DC%2BD1MXktFahsbg%3D
17. H. Kae C.J. Lim G.B. Spiegelman G. Weeks 2004 Chemoattractant-induced Ras activation during Dictyostelium aggregation EMBO Rep. 5 602 606 15143344 10.1038/sj.embor.7400151 1:CAS:528:DC%2BD2cXksVarsrg%3D (Pubitemid 39136422)
18. V. Kolsch P.G. Charest R.A. Firtel 2008 The regulation of cell motility and chemotaxis by phospholipid signaling J. Cell Sci. 121 551 559 18287584 10.1242/jcs.023333 1:CAS:528:DC%2BD1cXkslOmu7Y%3D (Pubitemid 351524153)
19. M.R. Kooistra N. Dube J.L. Bos 2007 Rap1: a key regulator in cell-cell junction formation J. Cell Sci. 120 17 22 17182900 10.1242/jcs.03306 1:CAS:528:DC%2BD2sXht1Gmsrc%3D (Pubitemid 46206645)
20. A. Kortholt P.J. van Haastert 2008 Highlighting the role of Ras and Rap during Dictyostelium chemotaxis Cell. Signal. 20 1415 1422 18385017 10.1016/j.cellsig.2008.02.006 1:CAS:528:DC%2BD1cXnsFKkur8%3D
21. S. Krugmann S. Andrews L. Stephens P.T. Hawkins 2006 ARAP3 is essential for formation of lamellipodia after growth factor stimulation J. Cell Sci. 119 425 432 16418224 10.1242/jcs.02755 1:CAS:528:DC%2BD28Xit1Klsbs%3D
22. R. Meili C. Ellsworth S. Lee T.B. Reddy H. Ma R.A. Firtel 1999 Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium EMBO J. 18 2092 2105 10205164 10.1093/emboj/18.8.2092 1:CAS:528:DyaK1MXivVOnu70%3D (Pubitemid 29179167)
23. K.C. Park F. Rivero R. Meili S. Lee F. Apone R.A. Firtel 2004 Rac regulation of chemotaxis and morphogenesis in Dictyostelium EMBO J. 23 4177 4189 15470506 10.1038/sj.emboj.7600368 1:CAS:528:DC%2BD2cXovFals78%3D (Pubitemid 39546156)
24. K. Parkinson P. Bolourani D. Traynor N.L. Aldren R.R. Kay G. Weeks C.R. Thompson 2009 Regulation of Rap1 activity is required for differential adhesion, cell-type patterning and morphogenesis in Dictyostelium J. Cell Sci. 122 335 344 19126673 10.1242/jcs.036822 1:CAS:528:DC%2BD1MXivVams7w%3D
25. J.H. Raaijmakers J.L. Bos 2009 Specificity in Ras and Rap signaling J. Biol. Chem. 284 10995 10999 19091745 10.1074/jbc.R800061200 1:CAS:528: DC%2BD1MXkslamsbw%3D
26. A.J. Ridley M.A. Schwartz K. Burridge R.A. Firtel M.H. Ginsberg G. Borisy J.T. Parsons A.R. Horwitz 2003 Cell migration: integrating signals from front to back Science 302 1704 1709 14657486 10.1126/science.1092053 1:CAS:528:DC%2BD3sXpsVWns7o%3D (Pubitemid 37505725)
27. A.A. Rodal O. Sokolova D.B. Robins K.M. Daugherty S. Hippenmeyer H. Riezman N. Grigorieff B.L. Goode 2005 Conformational changes in the Arp2/3 complex leading to actin nucleation Nat. Struct. Mol. Biol. 12 26 31 15592479 10.1038/nsmb870 1:CAS:528:DC%2BD2MXhtVWlsb0%3D (Pubitemid 40082913)
28. A.T. Sasaki R.A. Firtel 2006 Regulation of chemotaxis by the orchestrated activation of Ras, PI3K, and TOR Eur. J. Cell Biol. 85 873 895 16740339 10.1016/j.ejcb.2006.04.007 1:CAS:528:DC%2BD28XhtFyrt7fP (Pubitemid 44334734)
29. A.T. Sasaki C. Chun K. Takeda R.A. Firtel 2004 Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement J. Cell Biol. 167 505 518 15534002 10.1083/jcb.200406177 1:CAS:528: DC%2BD2cXpvVCnsrY%3D (Pubitemid 39489058)
30. L. Stephens L. Milne P. Hawkins 2008 Moving towards a better understanding of chemotaxis Curr. Biol. 18 R485 494 18522824 10.1016/j.cub.2008.04.048 1:CAS:528:DC%2BD1cXmsFymu78%3D (Pubitemid 351734644)
31. K.S. Uchida S. Yumura 2004 Dynamics of novel feet of Dictyostelium cells during migration J. Cell Sci. 117 1443 1455 15020673 10.1242/jcs.01015 1:CAS:528:DC%2BD2cXjs1ygurc%3D (Pubitemid 38559820)
32. P.J. van Haastert I. Keizer-Gunnink A. Kortholt 2007 Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis J. Cell Biol. 177 809 816 17535967 10.1083/jcb.200701134 (Pubitemid 46873087)