메뉴 건너뛰기




Volumn 132, Issue 1-2, 2012, Pages 176-185

Long-term treatment with the pure anti-estrogen fulvestrant durably remodels estrogen signaling in BG-1 ovarian cancer cells

Author keywords

4 Hydroxytamoxifen; Anti estrogens; BG1 cells; Cancer; Estrogen receptor; Fulvestrant; Ovary

Indexed keywords

AFIMOXIFENE; ESTROGEN RECEPTOR ALPHA; FULVESTRANT; HISTONE;

EID: 84864477585     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2012.05.006     Document Type: Article
Times cited : (9)

References (57)
  • 3
    • 84857579960 scopus 로고    scopus 로고
    • Molecular/Genetic therapies in ovarian cancer: Future opportunities and challenges
    • A.J. Ziebarth, C.N. Landen, and R.D. Alvarez Jr. Molecular/Genetic therapies in ovarian cancer: future opportunities and challenges Clinical Obstetrics and Gynecology 55 1 2012 156 172
    • (2012) Clinical Obstetrics and Gynecology , vol.55 , Issue.1 , pp. 156-172
    • Ziebarth, A.J.1    Landen, C.N.2    Alvarez, Jr.R.D.3
  • 4
    • 0347949497 scopus 로고    scopus 로고
    • Primary ovarian cancer chemotherapy: Current standards of care
    • W.P. McGuire, and M. Markman 3rd Primary ovarian cancer chemotherapy: current standards of care British Journal of Cancer 89 Suppl. 3 2003 S3 S8
    • (2003) British Journal of Cancer , vol.89 , Issue.SUPPL. 3
    • McGuire, W.P.1    Markman III, M.2
  • 5
    • 84863275781 scopus 로고    scopus 로고
    • Major clinical research advances in gynecologic cancer in 2011
    • D.H. Suh, K. Kim, and J.W. Kim Major clinical research advances in gynecologic cancer in 2011 Journal of Gynecologic Oncology 23 1 2011 53 64
    • (2011) Journal of Gynecologic Oncology , vol.23 , Issue.1 , pp. 53-64
    • Suh, D.H.1    Kim, K.2    Kim, J.W.3
  • 6
    • 10344219949 scopus 로고    scopus 로고
    • Characterization of intraperitoneal, orthotopic, and metastatic xenograft models of human ovarian cancer
    • DOI 10.1016/j.ymthe.2004.08.013, PII S1525001604014091
    • T.J. Shaw, M.K. Senterman, K. Dawson, C.A. Crane, and B.C. Vanderhyden Characterization of intraperitoneal, orthotopic, and metastatic xenograft models of human ovarian cancer Molecular Therapy 10 6 2004 1032 1042 (Pubitemid 39625247)
    • (2004) Molecular Therapy , vol.10 , Issue.6 , pp. 1032-1042
    • Shaw, T.J.1    Senterman, M.K.2    Dawson, K.3    Crane, C.A.4    Vanderhyden, B.C.5
  • 9
    • 0026620243 scopus 로고
    • Estradiol stimulates cell growth and secretion of procathepsin D and a 120-kilodalton protein in the human ovarian cancer cell line BG-1
    • DOI 10.1210/jc.75.6.1497
    • F. Galtier-Dereure, F. Capony, T. Maudelonde, and H. Rochefort Estradiol stimulates cell growth and secretion of procathepsin D and a 120-kilodalton protein in the human ovarian cancer cell line BG-1 Journal of Clinical Endocrinology and Metabolism 75 6 1992 1497 1502 (Pubitemid 23001410)
    • (1992) Journal of Clinical Endocrinology and Metabolism , vol.75 , Issue.6 , pp. 1497-1502
    • Galtier-Dereure, F.1    Capony, F.2    Maudelonde, T.3    Rochefort, H.4
  • 10
    • 0031027731 scopus 로고    scopus 로고
    • Steroid hormones and cancer: (II) lessons from experimental systems
    • DOI 10.1016/S0748-7983(97)80148-5
    • W.R. Miller, and S.P. Langdon Steroid hormones and cancer: (II) lessons from experimental systems European Journal of Surgical Oncology 23 1 1997 72 83 (Pubitemid 27107497)
    • (1997) European Journal of Surgical Oncology , vol.23 , Issue.1 , pp. 72-83
    • Miller, W.R.1    Langdon, S.P.2
  • 12
    • 3242728753 scopus 로고    scopus 로고
    • Estrogens and epithelial ovarian cancer
    • DOI 10.1016/j.ygyno.2004.03.026, PII S0090825804001994
    • S. Cunat, P. Hoffmann, and P. Pujol Estrogens and epithelial ovarian cancer Gynecologic Oncology 94 1 2004 25 32 (Pubitemid 38950494)
    • (2004) Gynecologic Oncology , vol.94 , Issue.1 , pp. 25-32
    • Cunat, S.1    Hoffmann, P.2    Pujol, P.3
  • 13
    • 0031768032 scopus 로고    scopus 로고
    • Increased immunostaining of fibulin-1, an estrogen-regulated protein in the stroma of human ovarian epithelial tumors
    • P. Roger, P. Pujol, A. Lucas, P. Baldet, and H. Rochefort Increased immunostaining of fibulin-1, an estrogen-regulated protein in the stroma of human ovarian epithelial tumors American Journal of Pathology 153 5 1998 1579 1588 (Pubitemid 28509915)
    • (1998) American Journal of Pathology , vol.153 , Issue.5 , pp. 1579-1588
    • Roger, P.1    Pujol, P.2    Lucas, A.3    Baldet, P.4    Rochefort, H.5
  • 14
    • 0023910777 scopus 로고
    • Ovarian cancer (review). Etiology, diagnosis, prognosis, surgery, radiotherapy, chemotherapy and endocrine therapy
    • B.J. Slotman, and B.R. Rao Ovarian cancer (review). Etiology, diagnosis, prognosis, surgery, radiotherapy, chemotherapy and endocrine therapy Anticancer Research 8 3 1988 417 434
    • (1988) Anticancer Research , vol.8 , Issue.3 , pp. 417-434
    • Slotman, B.J.1    Rao, B.R.2
  • 15
    • 0032401855 scopus 로고    scopus 로고
    • Differential expression of estrogen receptor-α and -β messenger RNAs as a potential marker of ovarian carcinogenesis
    • P. Pujol, J.M. Rey, P. Nirde, P. Roger, M. Gastaldi, F. Laffargue, H. Rochefort, and T. Maudelonde Differential expression of estrogen receptor-alpha and -beta messenger RNAs as a potential marker of ovarian carcinogenesis Cancer Research 58 23 1998 5367 5373 (Pubitemid 28551118)
    • (1998) Cancer Research , vol.58 , Issue.23 , pp. 5367-5373
    • Pujol, P.1    Rey, J.-M.2    Nirde, P.3    Roger, P.4    Gastaldi, M.5    Laffargue, F.6    Rochefort, H.7    Maudelonde, T.8
  • 16
    • 0036166523 scopus 로고    scopus 로고
    • Tamoxifen therapy for ovarian cancer in the adjuvant and advanced settings: Systematic review of the literature and implications for future research
    • DOI 10.1006/gyno.2001.6489
    • J.L. Perez-Gracia, and E.M. Carrasco Tamoxifen therapy for ovarian cancer in the adjuvant and advanced settings: systematic review of the literature and implications for future research Gynecologic Oncology 84 2 2002 201 209 (Pubitemid 34139799)
    • (2002) Gynecologic Oncology , vol.84 , Issue.2 , pp. 201-209
    • Perez-Gracia, J.L.1    Carrasco, E.M.2
  • 17
    • 0030201090 scopus 로고    scopus 로고
    • Tamoxifen in platinum-refractory ovarian cancer: A Gynecologic Oncology Group ancillary report
    • DOI 10.1006/gyno.1996.0181
    • M. Markman, K.A. Iseminger, K.D. Hatch, W.T. Creasman, W. Barnes, and B. Dubeshter Tamoxifen in platinum-refractory ovarian cancer: a Gynecologic Oncology Group Ancillary Report Gynecologic Oncology 62 1 1996 4 6 (Pubitemid 26234538)
    • (1996) Gynecologic Oncology , vol.62 , Issue.1 , pp. 4-6
    • Markman, M.1    Iseminger, K.A.2    Hatch, K.D.3    Creasman, W.T.4    Barnes M, W.5    Dubeshter, B.6
  • 18
    • 0033736524 scopus 로고    scopus 로고
    • Tamoxifen in the treatment of recurrent ovarian carcinoma
    • C. Trope, C. Marth, and J. Kaern Tamoxifen in the treatment of recurrent ovarian carcinoma European Journal of Cancer 36 Suppl. 4 2000 S59 S61
    • (2000) European Journal of Cancer , vol.36 , Issue.SUPPL. 4
    • Trope, C.1    Marth, C.2    Kaern, J.3
  • 22
    • 78649496224 scopus 로고    scopus 로고
    • Antiestrogen therapy in recurrent ovarian cancer resulting in 28 months of stable disease: A case report and review of the literature
    • R. Kothari, P. Argenta, J. Fowler, J. Carter, and W. Shimp Antiestrogen therapy in recurrent ovarian cancer resulting in 28 months of stable disease: a case report and review of the literature Archive of Oncology 18 1-2 2010 32 35
    • (2010) Archive of Oncology , vol.18 , Issue.12 , pp. 32-35
    • Kothari, R.1    Argenta, P.2    Fowler, J.3    Carter, J.4    Shimp, W.5
  • 23
    • 0026032112 scopus 로고
    • Endocrine factors in common epithelial ovarian cancer
    • B.R. Rao, and B.J. Slotman Endocrine factors in common epithelial ovarian cancer Endocrine Reviews 12 1 1991 14 26
    • (1991) Endocrine Reviews , vol.12 , Issue.1 , pp. 14-26
    • Rao, B.R.1    Slotman, B.J.2
  • 24
    • 0025935370 scopus 로고
    • Responsiveness of patients with advanced ovarian carcinoma to tamoxifen. A Gynecologic Oncology Group study of second-line therapy in 105 patients
    • K.D. Hatch, J.B. Beecham, J.A. Blessing, and W.T. Creasman Responsiveness of patients with advanced ovarian carcinoma to tamoxifen. A Gynecologic Oncology Group study of second-line therapy in 105 patients Cancer 68 2 1991 269 271
    • (1991) Cancer , vol.68 , Issue.2 , pp. 269-271
    • Hatch, K.D.1    Beecham, J.B.2    Blessing, J.A.3    Creasman, W.T.4
  • 25
    • 34548237309 scopus 로고    scopus 로고
    • Pathways to tamoxifen resistance
    • DOI 10.1016/j.canlet.2007.03.016, PII S0304383507001541
    • R.B. Riggins, R.S. Schrecengost, M.S. Guerrero, and A.H. Bouton Pathways to tamoxifen resistance Cancer Letters 256 1 2007 1 24 (Pubitemid 47333324)
    • (2007) Cancer Letters , vol.256 , Issue.1 , pp. 1-24
    • Riggins, R.B.1    Schrecengost, R.S.2    Guerrero, M.S.3    Bouton, A.H.4
  • 26
    • 0035101145 scopus 로고    scopus 로고
    • Cellular and molecular pharmacology of antiestrogen action and resistance
    • R. Clarke, F. Leonessa, J.N. Welch, and T.C. Skaar Cellular and molecular pharmacology of antiestrogen action and resistance Pharmacological Reviews 53 1 2001 25 71 (Pubitemid 32173107)
    • (2001) Pharmacological Reviews , vol.53 , Issue.1 , pp. 25-71
    • Clarke, R.1    Leonessa, F.2    Welch, J.N.3    Skaar, T.C.4
  • 27
    • 36849020052 scopus 로고    scopus 로고
    • Tamoxifen resistance and epigenetic modifications in breast cancer cell lines
    • E. Badia, J. Oliva, P. Balaguer, and V. Cavailles Tamoxifen resistance and epigenetic modifications in breast cancer cell lines Current Medicinal Chemistry 14 28 2007 3035 3045
    • (2007) Current Medicinal Chemistry , vol.14 , Issue.28 , pp. 3035-3045
    • Badia, E.1    Oliva, J.2    Balaguer, P.3    Cavailles, V.4
  • 28
    • 13944275572 scopus 로고    scopus 로고
    • Effects of prolonged tamoxifen treatment on receptor expression and apoptosis of ovarian cancer cells
    • DOI 10.1016/j.ygyno.2004.11.023
    • R. Zhou, O. Treeck, F. Horn, and O. Ortmann Effects of prolonged tamoxifen treatment on receptor expression and apoptosis of ovarian cancer cells Gynecologic Oncology 96 3 2005 678 683 (Pubitemid 40267684)
    • (2005) Gynecologic Oncology , vol.96 , Issue.3 , pp. 678-683
    • Zhou, R.1    Treeck, O.2    Horn, F.3    Ortmann, O.4
  • 29
    • 0024489926 scopus 로고
    • Characterization of a human ovarian carcinoma cell line with estrogen and progesterone receptors
    • DOI 10.1002/1097-0142(19890115)63:2<280::AID-CNCR2820630213>3.0. CO;2-N
    • K.R. Geisinger, T.E. Kute, M.J. Pettenati, C.E. Welander, Y. Dennard, L.A. Collins, and M.E. Berens Characterization of a human ovarian carcinoma cell line with estrogen and progesterone receptors Cancer 63 2 1989 280 288 (Pubitemid 19035019)
    • (1989) Cancer , vol.63 , Issue.2 , pp. 280-288
    • Geisinger, K.R.1    Kute, T.E.2    Pettenati, M.J.3    Welander, C.E.4    Dennard, Y.5    Collins, L.A.6    Berens, M.E.7
  • 30
    • 0033304585 scopus 로고    scopus 로고
    • Selective promoter usage of the human estrogen receptor-α gene and its regulation by estrogen
    • C. Donaghue, B.R. Westley, and F.E. May Selective promoter usage of the human estrogen receptor-alpha gene and its regulation by estrogen Molecular Endocrinology 13 11 1999 1934 1950 (Pubitemid 30645266)
    • (1999) Molecular Endocrinology , vol.13 , Issue.11 , pp. 1934-1950
    • Donaghue, C.1    Westley, B.R.2    May, F.E.B.3
  • 31
    • 34347262483 scopus 로고    scopus 로고
    • Differential regulation of estrogen receptor α turnover and transactivation by Mdm2 and stress-inducing agents
    • DOI 10.1158/0008-5472.CAN-07-0967
    • V. Duong, N. Boulle, S. Daujat, J. Chauvet, S. Bonnet, H. Neel, and V. Cavailles Differential regulation of estrogen receptor alpha turnover and transactivation by Mdm2 and stress-inducing agents Cancer Research 67 11 2007 5513 5521 (Pubitemid 46997293)
    • (2007) Cancer Research , vol.67 , Issue.11 , pp. 5513-5521
    • Duong, V.1    Boulle, N.2    Daujat, S.3    Chauvet, J.4    Bonnet, S.5    Neel, H.6    Cavailles, V.7
  • 33
    • 34447130861 scopus 로고    scopus 로고
    • Positive cross-regulatory loop ties GATA-3 to estrogen receptor α expression in breast cancer
    • DOI 10.1158/0008-5472.CAN-07-0746
    • J. Eeckhoute, E.K. Keeton, M. Lupien, S.A. Krum, J.S. Carroll, and M. Brown Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer Cancer Research 67 13 2007 6477 6483 (Pubitemid 47037533)
    • (2007) Cancer Research , vol.67 , Issue.13 , pp. 6477-6483
    • Eeckhoute, J.1    Keeton, E.K.2    Lupien, M.3    Krum, S.A.4    Carroll, J.S.5    Brown, M.6
  • 34
    • 0035208142 scopus 로고    scopus 로고
    • Minireview: Genomic organization of the human ERα gene promoter region
    • DOI 10.1210/me.15.12.2057
    • M. Kos, G. Reid, S. Denger, and F. Gannon Minireview: genomic organization of the human ER alpha gene promoter region Molecular Endocrinology 15 12 2001 2057 2063 (Pubitemid 33141126)
    • (2001) Molecular Endocrinology , vol.15 , Issue.12 , pp. 2057-2063
    • Kos, M.1    Reid, G.2    Denger, S.3    Gannon, F.4
  • 35
    • 0036286677 scopus 로고    scopus 로고
    • Human estrogen receptor-α: Regulation by synthesis, modification and degradation
    • DOI 10.1007/s00018-002-8470-2
    • G. Reid, S. Denger, M. Kos, and F. Gannon Human estrogen receptor-alpha: regulation by synthesis, modification and degradation Cellular and Molecular Life Sciences 59 5 2002 821 831 (Pubitemid 34628243)
    • (2002) Cellular and Molecular Life Sciences , vol.59 , Issue.5 , pp. 821-831
    • Reid, G.1    Denger, S.2    Kos, M.3    Gannon, F.4
  • 36
    • 0028906739 scopus 로고
    • Estrogen target tissue determines alternative promoter utilization of the human estrogen receptor gene in osteoblasts and tumor cell lines
    • K. Grandien, M. Backdahl, O. Ljunggren, J.A. Gustafsson, and A. Berkenstam Estrogen target tissue determines alternative promoter utilization of the human estrogen receptor gene in osteoblasts and tumor cell lines Endocrinology 136 5 1995 2223 2229
    • (1995) Endocrinology , vol.136 , Issue.5 , pp. 2223-2229
    • Grandien, K.1    Backdahl, M.2    Ljunggren, O.3    Gustafsson, J.A.4    Berkenstam, A.5
  • 37
    • 0029025109 scopus 로고
    • Quantitative analysis of the transcriptional start sites of estrogen receptor in breast carcinoma
    • R.J. Weigel, D.L. Crooks, J.D. Iglehart, and E.C. deConinck Quantitative analysis of the transcriptional start sites of estrogen receptor in breast carcinoma Cell Growth & Differentiation 6 6 1995 707 711
    • (1995) Cell Growth & Differentiation , vol.6 , Issue.6 , pp. 707-711
    • Weigel, R.J.1    Crooks, D.L.2    Iglehart, J.D.3    Deconinck, E.C.4
  • 39
    • 0019813814 scopus 로고
    • Determination of tamoxifen and biologically active metabolites in human breast tumours and plasma
    • P. Daniel, S.J. Gaskell, H. Bishop, C. Campbell, and R.I. Nicholson Determination of tamoxifen and biologically active metabolites in human breast tumours and plasma European Journal of Cancer and Clinical Oncology 17 11 1981 1183 1189 (Pubitemid 12247998)
    • (1981) European Journal of Cancer and Clinical Oncology , vol.17 , Issue.11 , pp. 1183-1189
    • Daniel, P.1    Gaskell, S.J.2    Bishop, H.3
  • 40
    • 0034012358 scopus 로고    scopus 로고
    • Concentrations of tamoxifen and its major metabolites in hormone responsive and resistant breast tumours
    • J. MacCallum, J. Cummings, J.M. Dixon, and W.R. Miller Concentrations of tamoxifen and its major metabolites in hormone responsive and resistant breast tumours British Journal of Cancer 82 10 2000 1629 1635 (Pubitemid 30229571)
    • (2000) British Journal of Cancer , vol.82 , Issue.10 , pp. 1629-1635
    • MacCallum, J.1    Cummings, J.2    Dixon, J.M.3    Miller, W.R.4
  • 42
    • 0019411776 scopus 로고
    • Hydroxylated metabolites of tamoxifen are formed in vivo and bound to estrogen receptor in target tissues
    • J.L. Borgna, and H. Rochefort Hydroxylated metabolites of tamoxifen are formed in vivo and bound to estrogen receptor in target tissues Journal of Biological Chemistry 256 2 1981 859 868 (Pubitemid 11103040)
    • (1981) Journal of Biological Chemistry , vol.256 , Issue.2 , pp. 859-868
    • Borgna, J.-L.1    Rochefort, H.2
  • 43
    • 0020003085 scopus 로고
    • 7 cells: Correlation between binding to estrogen receptor and inhibition of cell growth
    • E. Coezy, J.L. Borgna, and H. Rochefort Tamoxifen and metabolites in MCF7 cells: correlation between binding to estrogen receptor and inhibition of cell growth Cancer Research 42 1 1982 317 323 (Pubitemid 12207285)
    • (1982) Cancer Research , vol.42 , Issue.1 , pp. 317-323
    • Coezy, E.1    Borgna, J.L.2    Rochefort, H.3
  • 44
    • 0035525593 scopus 로고    scopus 로고
    • ICI 182,780 (Fulvestrant™) - The first oestrogen receptor down-regulator - Current clinical data
    • J.F. Robertson ICI 182,780 (Fulvestrant) - the first oestrogen receptor down-regulator - current clinical data British Journal of Cancer 85 Suppl. 2 2001 11 14 (Pubitemid 33753504)
    • (2001) British Journal of Cancer , vol.85 , Issue.3332 , pp. 11-14
    • Robertson, J.F.R.1
  • 45
    • 1842684035 scopus 로고    scopus 로고
    • Fulvestrant: An oestrogen receptor antagonist with a novel mechanism of action
    • C.K. Osborne, A. Wakeling, and R.I. Nicholson Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action British Journal of Cancer 90 Suppl. 1 2004 S2 S6
    • (2004) British Journal of Cancer , vol.90 , Issue.SUPPL. 1
    • Osborne, C.K.1    Wakeling, A.2    Nicholson, R.I.3
  • 46
    • 0034901325 scopus 로고    scopus 로고
    • ICI 182,780 acts as a partial agonist and antagonist of estradiol effects in specific cells of the sheep uterus
    • DOI 10.1016/S0960-0760(01)00061-9, PII S0960076001000619
    • J.A. Robertson, Y. Zhang, and N.H. Ing ICI 182,780 acts as a partial agonist and antagonist of estradiol effects in specific cells of the sheep uterus Journal of Steroid Biochemistry and Molecular Biology 77 4-5 2001 281 287 (Pubitemid 32703626)
    • (2001) Journal of Steroid Biochemistry and Molecular Biology , vol.77 , Issue.4-5 , pp. 281-287
    • Robertson, J.A.1    Zhang, Y.2    Ing, N.H.3
  • 47
    • 0037099717 scopus 로고    scopus 로고
    • Antiestrogen ICI 182,780 decreases proliferation of insulin-like growth factor I (IGF-I)-treated MCF-7 cells without inhibiting IGF-I signaling
    • H. Varma, and S.E. Conrad Antiestrogen ICI 182,780 decreases proliferation of insulin-like growth factor I (IGF-I)-treated MCF-7 cells without inhibiting IGF-I signaling Cancer Research 62 14 2002 3985 3991 (Pubitemid 34791064)
    • (2002) Cancer Research , vol.62 , Issue.14 , pp. 3985-3991
    • Varma, H.1    Conrad, S.E.2
  • 48
    • 34047275592 scopus 로고    scopus 로고
    • Effects of 4-hydroxytamoxifen, raloxifene and ICI 182,780 on survival of uterine cancer cell lines in the presence and absence of exogenous estrogens
    • K. Leblanc, E. Sexton, S. Parent, G. Belanger, M.C. Dery, V. Boucher, and E. Asselin Effects of 4-hydroxytamoxifen, raloxifene and ICI 182,780 on survival of uterine cancer cell lines in the presence and absence of exogenous estrogens International Journal of Oncology 30 2 2007 477 487
    • (2007) International Journal of Oncology , vol.30 , Issue.2 , pp. 477-487
    • Leblanc, K.1    Sexton, E.2    Parent, S.3    Belanger, G.4    Dery, M.C.5    Boucher, V.6    Asselin, E.7
  • 50
    • 65349088088 scopus 로고    scopus 로고
    • Cell growth of ovarian cancer cells is stimulated by xenoestrogens through an estrogen-dependent pathway, but their stimulation of cell growth appears not to be involved in the activation of the mitogen-activated protein kinases ERK-1 and p38
    • S.H. Park, K.Y. Kim, B.S. An, J.H. Choi, E.B. Jeung, P.C. Leung, and K.C. Choi Cell growth of ovarian cancer cells is stimulated by xenoestrogens through an estrogen-dependent pathway, but their stimulation of cell growth appears not to be involved in the activation of the mitogen-activated protein kinases ERK-1 and p38 Journal of Reproduction and Development 55 1 2009 23 29
    • (2009) Journal of Reproduction and Development , vol.55 , Issue.1 , pp. 23-29
    • Park, S.H.1    Kim, K.Y.2    An, B.S.3    Choi, J.H.4    Jeung, E.B.5    Leung, P.C.6    Choi, K.C.7
  • 51
    • 0029002319 scopus 로고
    • Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression
    • A.T. Ferguson, R.G. Lapidus, S.B. Baylin, and N.E. Davidson Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression Cancer Research 55 11 1995 2279 2283
    • (1995) Cancer Research , vol.55 , Issue.11 , pp. 2279-2283
    • Ferguson, A.T.1    Lapidus, R.G.2    Baylin, S.B.3    Davidson, N.E.4
  • 52
    • 0028077625 scopus 로고
    • Hydroxytamoxifen induces a rapid and irreversible inactivation of an estrogenic response in an MCF-7-derived cell line
    • E. Badia, M.J. Duchesne, S. Fournier-Bidoz, A.E. Simar-Blanchet, B. Terouanne, J.C. Nicolas, and M. Pons Hydroxytamoxifen induces a rapid and irreversible inactivation of an estrogenic response in an MCF-7-derived cell line Cancer Research 54 22 1994 5860 5866 (Pubitemid 24375220)
    • (1994) Cancer Research , vol.54 , Issue.22 , pp. 5860-5866
    • Badia, E.1    Duchesne, M.-J.2    Fournier-Bidoz, S.3    Simar-Blanchet, A.-E.4    Terouanne, B.5    Nicolas, J.-C.6    Pons, M.7
  • 53
    • 0031964203 scopus 로고    scopus 로고
    • Rapid tamoxifen-induced inactivation of an estrogenic response is accompanied by a localized epigenetic modification but not by mutations
    • DOI 10.1023/A:1005801005966
    • E. Badia, M.J. Duchesne, J.C. Nicolas, and M. Pons Rapid tamoxifen-induced inactivation of an estrogenic response is accompanied by a localized epigenetic modification but not by mutations Breast Cancer Research and Treatment 47 1 1998 71 81 (Pubitemid 28048153)
    • (1998) Breast Cancer Research and Treatment , vol.47 , Issue.1 , pp. 71-81
    • Badia, E.1    Duchesne, M.-J.2    Nicolas, J.-C.3    Pons, M.4
  • 54
    • 23644452485 scopus 로고    scopus 로고
    • Involvement of HP1α protein in irreversible transcriptional inactivation by antiestrogens in breast cancer cells
    • DOI 10.1016/j.febslet.2005.06.060, PII S0014579305008069
    • J. Oliva, S. El Messaoudi, F. Pellestor, M. Fuentes, V. Georget, P. Balaguer, V. Cavailles, F. Vignon, and E. Badia Involvement of HP1alpha protein in irreversible transcriptional inactivation by antiestrogens in breast cancer cells FEBS Letters 579 20 2005 4278 4286 (Pubitemid 41116352)
    • (2005) FEBS Letters , vol.579 , Issue.20 , pp. 4278-4286
    • Oliva, J.1    El Messaoudi, S.2    Pellestor, F.3    Fuentes, M.4    Georget, V.5    Balaguer, P.6    Cavailles, V.7    Vignon, F.8    Badia, E.9
  • 56
    • 34250843675 scopus 로고    scopus 로고
    • The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-α (ERα) and represses ERα messenger RNA and protein expression in breast cancer cell lines
    • DOI 10.1210/me.2007-0022
    • B.D. Adams, H. Furneaux, and B.A. White The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines Molecular Endocrinology 21 5 2007 1132 1147 (Pubitemid 46984764)
    • (2007) Molecular Endocrinology , vol.21 , Issue.5 , pp. 1132-1147
    • Adams, B.D.1    Furneaux, H.2    White, B.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.