Experimental radiation-induced heart disease: Past, present, and future

Radiation Research

Volumn 178, Issue 1, 2012, Pages 1-6

  Boerma, Marjan ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; COLLAGEN TYPE 3; PENTOXIFYLLINE;

ARTICLE; ATHEROSCLEROSIS; CANCER RADIOTHERAPY; CARDIOMYOPATHY; CARDIOTOXICITY; CARDIOVASCULAR RISK; CLINICAL FEATURE; DISEASE SEVERITY; HEART DISEASE; HEART MUSCLE FIBROSIS; HISTOPATHOLOGY; HUMAN; HYPERTENSION; INCIDENCE; IONIZING RADIATION; KALLIKREIN KININ SYSTEM; MORBIDITY; MORTALITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OBESITY; PERICARDIAL DISEASE; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INDUCED HEART DISEASE; RADIATION INJURY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SMOKING; VALVULAR HEART DISEASE;

ANIMALS; ENDOTHELIN-1; HEART DISEASES; HUMANS; MAST CELLS; RADIATION INJURIES, EXPERIMENTAL; RADIOTHERAPY; THORACIC NEOPLASMS;

ANIMALIA;

EID: 84864461642     PISSN: 00337587     EISSN: 19385404     Source Type: Journal    
DOI: 10.1667/RR2933.1     Document Type: Article

References (57)

1. Adams MJ, Lipsitz SR, Colan SD, Tarbell NJ, Treves ST, Diller L, et al. Cardiovascular status in long-term survivors of Hodgkin's disease treated with chest radiotherapy. J Clin Oncol 2004; 22:3139-48.
2. Heidenreich PA, Hancock SL, Vagelos RH, Lee BK, Schnittger I. Diastolic dysfunction after mediastinal irradiation. Am Heart J 2005; 150:977-82.
3. Early Breast Cancer Trialists Collaborative Group. Favourable and unfavourable effects on long-term survival of radiotherapy for early breast cancer: an overview of the randomised trials. Lancet 2000; 355:1757-70.
4. Hooning MJ, Aleman BM, van Rosmalen AJ, Kuenen MA, Klijn JG, van Leeuwen FE. Cause-specific mortality in long-term survivors of breast cancer: A 25-year follow-up study. Int J Radiat Oncol Biol Phys 2006; 64:1081-91.
5. McGale P, Darby SC, Hall P, Adolfsson J, Bengtsson NO, Bennet AM, et al. Incidence of heart disease in 35,000 women treated with radiotherapy for breast cancer in Denmark and Sweden. Radiother Oncol 2011; 100:167-75.
6. Adams MJ, Hardenbergh PH, Constine LS, Lipshultz SE. Radiation-associated cardiovascular disease. Crit Rev Oncol Hematol 2003; 45:55-75.
7. Heidenreich PA, Kapoor Jr. Radiation induced heart disease: systemic disorders in heart disease. Heart 2009; 95:252-8.
8. Kole TP, Aghayere O, Kwah J, Yorke ED, Goodman KA. Comparison of Heart and Coronary Artery Doses Associated with Intensity-Modulated Radiotherapy Versus Three-Dimensional Conformal Radiotherapy for Distal Esophageal Cancer. Int J Radiat Oncol Biol Phys 2012; In press.
9. Chera BS, Rodriguez C, Morris CG, Louis D, Yeung D, Li Z, et al. Dosimetric comparison of three different involved nodal irradiation techniques for stage II Hodgkin's lymphoma patients: conventional radiotherapy, intensity-modulated radiotherapy, and three-dimensional proton radiotherapy. Int J Radiat Oncol Biol Phys 2009; 75:1173-80.
10. McGale P, Darby SC. Low doses of ionizing radiation and circulatory diseases: a systematic review of the published epidemiological evidence. Radiat Res 2005; 163:247-57.
11. Tillman GF, Pawlicki T, Koong AC, Goodman KA. Preoperative versus postoperative radiotherapy for locally advanced gastroesophageal junction and proximal gastric cancers: a comparison of normal tissue radiation doses. Dis Esophagus 2008; 21:437-44.
12. Weber DC, Peguret N, Dipasquale G, Cozzi L. Involved-node and involved-field volumetric modulated arc vs. fixed beam intensitymodulated radiotherapy for female patients with early-stage supradiaphragmatic Hodgkin lymphoma: a comparative planning study. Int J Radiat Oncol Biol Phys 2009; 75:1578-86.
13. Wu WC, Chan CL, Wong YW, Cuijpers JP. A study on the influence of breathing phases in intensity-modulated radiotherapy of lung tumours using four-dimensional CT. Br J Radiol 2009; 83:252-6.
14. Darby SC, McGale P, Taylor CW, Peto R. Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: prospective cohort study of about 300,000 women in US SEER cancer registries. Lancet Oncol 2005; 6:557-65.
15. Haque R, Yood MU, Geiger AM, Kamineni A, Avila CC, Shi J, et al. Long-term safety of radiotherapy and breast cancer laterality in older survivors. Cancer Epidemiol Biomark Prev 2011; 20:2120-6.
16. Harris EE, Correa C, Hwang WT, Liao J, Litt HI, Ferrari VA, et al. Late cardiac mortality and morbidity in early-stage breast cancer patients after breast-conservation treatment. J Clin Oncol 2006; 24:4100-6.
17. Ozasa K, Shimizu Y, Suyama A, Kasagi F, Soda M, Grant EJ, et al. Studies of the mortality of atomic bomb survivors, report 14, 1950-2003: an overview of cancer and noncancer diseases. Radiat Res 2011; 177:229-43.
18. Preston DL, Shimizu Y, Pierce DA, Suyama A, Mabuchi K. Studies of mortality of atomic bomb survivors. Report 13: Solid cancer and noncancer disease mortality: 1950-1997. Radiat Res 2003; 160:381-407.
19. Adams MJ, Grant EJ, Kodama K, Shimizu Y, Kasagi F, Suyama A, et al. Radiation dose associated with renal failure mortality: a potential pathway to partially explain increased cardiovascular disease mortality observed after whole-body irradiation. Radiat Res 2011; 177:220-8.
20. Little MP, Tawn EJ, Tzoulaki I, Wakeford R, Hildebrandt G, Paris F, et al. A systematic review of epidemiological associations between low and moderate doses of ionizing radiation and late cardiovascular effects, and their possible mechanisms. Radiat Res 2008; 169:99-109.
21. Schultz-Hector S, Trott KR. Radiation-induced cardiovascular diseases: Is the epidemiologic evidence compatible with the radiobiologic data? Int J Radiat Oncol Biol Phys 2007; 67:10-8.
22. Stewart AM, Kneale GW. A-bomb survivors: factors that may lead to a re-assessment of the radiation hazard. Int J Epidemiol 2000; 29:708-14.
23. Azizova TV, Muirhead CR, Druzhinina MB, Grigoryeva ES, Vlasenko EV, Sumina MV, et al. Cardiovascular diseases in the cohort of workers first employed at Mayak PA in 1948-1958. Radiat Res 2010; 174:155-68.
24. Hoel DG. Ionizing radiation and cardiovascular disease. Ann N Y Acad Sci 2006; 1076:309-17.
25. Shimizu Y, Kodama K, Nishi N, Kasagi F, Suyama A, Soda M, et al. Radiation exposure and circulatory disease risk: Hiroshima and Nagasaki atomic bomb survivor data, 1950-2003. BMJ 2010; 340:b5349.
26. Fajardo LF, Stewart Jr. Pathogenesis of radiation-induced myocardial fibrosis. Lab Invest 1973; 29:244-57.
27. Kruse JJ, Zurcher C, Strootman EG, Bart CI, Schlagwein N, Leer JW, et al. Structural changes in the auricles of the rat heart after local ionizing irradiation. Radiother Oncol 2001; 58:303-11.
28. Labudova O, Hardmeier R, Rink H, Lubec G. The transcription of the XRCC1 gene in the heart of radiation-resistant and radiationsensitive mice after ionizing irradiation. Pediatr Res 1997; 41:435-9.
29. Lauk S, Kiszel Z, Buschmann J, Trott KR. Radiation-induced heart disease in rats. Int J Radiat Oncol Biol Phys 1985; 11:801-8.
30. McChesney SL, Gillette EL, Powers BE. Radiation-induced cardiomyopathy in the dog. Radiat Res 1988; 113:120-32.
31. Gold H. Atherosclerosis in the rat. Effect of X-ray and a high fat diet. Proc Soc Exp Biol Med 1962; 111:593-5.
32. Lauk S, Trott KR. Radiation induced heart disease in hypertensive rats. Int J Radiat Oncol Biol Phys 1988; 14:109-14.
33. Brosius FC, Waller BF, Roberts WC. Radiation heart disease. Analysis of 16 young (aged 15 to 33 years) necropsy patients who received over 3,500 rads to the heart. Am J Med 1981; 70:519-30.
34. Hamza A, Tunick PA, Kronzon I. Echocardiographic manifestations of complications of radiation therapy. Echocardiography 2009; 26:724-8.
35. Veinot JP, Edwards WD. Pathology of radiation-induced heart disease: a surgical and autopsy study of 27 cases. Hum Pathol 1996; 27:766-73.
36. Boerma M, Zurcher C, Esveldt I, Schutte-Bart CI, Wondergem J. Histopathology of ventricles, coronary arteries and mast cell accumulation in transverse and longitudinal sections of the rat heart after irradiation. Oncol Rep 2004; 12:213-9.
37. Tsujimura T, Hirota S, Nomura S, Niwa Y, Yamazaki M, Tono T, et al. Characterization of Ws mutant allele of rats: a 12-base deletion in tyrosine kinase domain of c-kit gene. Blood 1991; 78:1942-6.
38. Boerma M, Wang J, Wondergem J, Joseph J, Qiu X, Kennedy RH, et al. Influence of mast cells on structural and functional manifestations of radiation-induced heart disease. Cancer Res 2005; 65:3100-7.
39. Koike MK, de Carvalho FC, de Lourdes HM. Bradykinin B2 receptor antagonism attenuates inflammation, mast cell infiltration and fibrosis in remote myocardium after infarction in rats. Clin Exp Pharmacol Physiol 2005; 32:1131-6.
40. Sharma JN. Cardiovascular activities of the bradykinin system. ScientificWorldJournal 2008; 8:384-93.
41. Yeh CH, Chen TP, Wang YC, Lin YM, Fang SW. Cardiomyocytic apoptosis limited by bradykinin via restoration of nitric oxide after cardioplegic arrest. J Surg Res 2010; 163:e1-e9.
42. Yin H, Chao L, Chao J. Nitric oxide mediates cardiac protection of tissue kallikrein by reducing inflammation and ventricular remodeling after myocardial ischemia/reperfusion. Life Sci 2008; 82:156-65.
43. Coffman LG, Brown JC, Johnson DA, Parthasarathy N, D'Agostino RB, Jr., Lively MO, et al. Cleavage of high-molecular-weight kininogen by elastase and tryptase is inhibited by ferritin. Am J Physiol Lung Cell Mol Physiol 2008; 294:L505-L515.
44. Imamura T, Dubin A, Moore W, Tanaka R, Travis J. Induction of vascular permeability enhancement by human tryptase: dependence on activation of prekallikrein and direct release of bradykinin from kininogens. Lab Invest 1996; 74:861-70.
45. Damas J, Adam A. Congenital deficiency in plasma kallikrein and kininogens in the brown Norway rat. Experientia 1980; 36:586-7.
46. Kaschina E, Stoll M, Sommerfeld M, Steckelings UM, Kreutz R, Unger T. Genetic kininogen deficiency contributes to aortic aneurysm formation but not to atherosclerosis. Physiol Genomics 2004; 19:41-9.
47. Maurer M, Wedemeyer J, Metz M, Piliponsky AM, Weller K, Chatterjea D, et al. Mast cells promote homeostasis by limiting endothelin-1-induced toxicity. Nature 2004; 432:512-6.
48. Boerma M, Wang J, Kulkarni A, Roberto KA, Qiu X, Kennedy RH, et al. Influence of endothelin-1 receptor inhibition on functional, structural and molecular changes in the rat heart after irradiation. Radiat Res 2008; 170:275-83.
49. Clozel M, Gray GA, Breu V, Loffler BM, Osterwalder R. The endothelin ETB receptor mediates both vasodilation and vasoconstriction in vivo. Biochem Biophys Res Commun 1992; 186:867-73.
50. Boerma M, Roberto KA, Hauer-Jensen M. Prevention and treatment of functional and structural radiation injury in the rat heart by pentoxifylline and alpha-tocopherol. Int J Radiat Oncol Biol Phys 2008; 72:170-7.
51. Liu H, Xiong M, Xia YF, Cui NJ, Lu RB, Deng L, et al. Studies on pentoxifylline and tocopherol combination for radiation-induced heart disease in rats. Int J Radiat Oncol Biol Phys 2009; 73:1552-9.
52. Verhaegen F, Granton P, Tryggestad E. Small animal radiotherapy research platforms. Phys Med Biol 2011; 56:R55-R83.
53. Bell RM, Mocanu MM, Yellon DM. Retrograde heart perfusion: the Langendorff technique of isolated heart perfusion. J Mol Cell Cardiol 2011; 50:940-50.
54. Wondergem J, van der Laarse A, Van Ravels FJ, van Wermeskerken AM, Verhoeve HR, de Graaf BW, et al. In vitro assessment of cardiac performance after irradiation using an isolated working rat heart preparation. Int J Radiat Biol 1991; 59:1053-68.
55. Goergen CJ, Sosnovik DE. From molecules to myofibers: multiscale imaging of the myocardium. J Cardiovasc Transl Res 2011; 4:493-503.
56. Kagadis GC, Loudos G, Katsanos K, Langer SG, Nikiforidis GC. In vivo small animal imaging: current status and future prospects. Med Phys 2010; 37:6421-42.
57. Seemann I, Gabriels K, Visser NL, Hoving S, te Poele JA, Pol JF, et al. Irradiation induced modest changes in murine cardiac function despite progressive structural damage to the myocardium and microvasculature. Radiother Oncol 2012; 103:143-50.