Structural changes in the auricles of the rat heart after local ionizing irradiation

Radiotherapy and Oncology

Volumn 58, Issue 3, 2001, Pages 303-311

  Krüse, Jacqueline J C M ^a   Zurcher, Chris ^a,b   Strootman, Erwin G ^a   Bart, Cindy I ^a   Schlagwein, Nicole ^a   Leer, Jan Willem H ^a,c   Wondergem, Jan ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Auricles; Cytokines; End diastolic diameter; Fibrosis; Ionizing irradiation; Rat heart

Indexed keywords

INTERLEUKIN 1BETA; MESSENGER RNA; PROCOLLAGEN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ARTICLE; BLOOD PUMP; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GENE EXPRESSION; HEART FUNCTION; HEART LEFT ATRIUM; HEART MUSCLE FIBROSIS; HISTOPATHOLOGY; IONIZING RADIATION; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION RESPONSE; RAT;

ANIMALS; ATRIAL APPENDAGE; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; FIBROSIS; HEART ATRIA; INTERLEUKIN-1; MYOCARDIUM; POLYMERASE CHAIN REACTION; PROCOLLAGEN; RADIATION DOSAGE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 0035282720     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-8140(00)00327-3     Document Type: Article

References (53)

1. Latency and activation in the control of TGF-β1
2. Dose fractionation, dose rate and iso-effect relationships for normal tissue responses
3. Atrial natriuretic peptide: A hormone with implications for clinical practice
4. Enhanced deposition of predominantly type I collagen in myocardial disease
5. Molecular and cellular basis of radiation fibrosis
6. The collagen network of the heart
7. Radiation-induced changes in the ultrastructure and mechanical function of the rat heart
8. Radiation-induced damage of the Wistar rat heart: Biochemistry and function
9. Radiotherapy as a cause of complete atrioventricular block in Hodgkin's disease
10. Atrial natriuretic peptide: A new cardiac hormone
11. Compliance of left atrium with and without left atrial appendage
12. Collagen network remodeling and diastolic stiffness of rat left ventricle with pressure overload hypertrophy
13. Collagen accumulation in the heart ventricles as function of growth and ageing
14. Experimental radiation-induced heart disease
15. Radiation response of the canine cardiovascular system
16. Heart size and function after radiation therapy to the mediastinum in patients with Hodgkin's disease
17. Late cardiac effects of therapeutic mediastinal irradiation. Assessment by echocardiography and radiouclide angiography
18. The reservoir function of the left atrium during ventricular systole
19. Late cardiac effects after mantle radiotherapy in patients with Hodgkin's disease
20. TGF-1β-mediated alterations of rat lung fibroblast differentiation resulting in the radiation-induced fibrotic phenotype
21. Cardiac disease following treatment of Hodgkin's disease in children and adolescents
22. Ultrastructural injury in the atrium after radiation of the rat heart
23. Regional atrial distensibility
24. Altered left atrial compliance after atrial appendectomy: Influence on left atrial and ventricular filling
25. Picrosirius staining plus polarization microscopy: A specific method for collagen detection in tissue sections
26. Functional and morphological damage after local heart irradiation and/or adriamycin in Wistar rats
27. Detection and quantitative measurement of transforming growth factor-β1 (TGF-β1) gene expression using a semi-nested competitive PCR assay
28. Changes in transforming growth factor-β1 (TGF-β1), procollagen types I and III mRNA in the rat heart after irradiation
29. Radiation-induced heart disease in rats
30. TGF-β1 and radiation fibrosis: A master switch and a specific therapeutic target?
31. Radiation-induced cardiomyopathy in the dog
32. Early radiation response of the canine heart and lung
33. Late cardiac, thyroid and pulmonary sequelae of mantleradiotherapy for Hodgkin's disease
34. Dilated cardiomyopathy is associated with significant changes in collagen type I/III ratio
35. Cardiac disease after chest irradiation for Hodgkin's disease: Incidence in 108 patients with long follow-up
36. Ischemic heart disease after mantlefleld irradiation for Hodgkin's disease in longterm follow-up
37. Long-term overproduction of collagen in radiation-induced fibrosis
38. Terminal differentiation of human fibroblasts is induced by radiation
39. Cellular basis of radiation-induced fibrosis
40. Irradiation-induced pericarditis
41. Radiation-induced heart disease: Review of experimental data on dose response and pathogenesis
42. A novel multispecific competitor for quantitative PCR analysis of cytokine gene expression in rats
43. Radiation injury to the heart
44. Generation of competitor DNA fragments for quantitative PCR
45. Radiation-induced valvular dysfunction
46. Cardiac interstitium in health and disease: The fibrillar collagen network
47. Radiation pericarditis and myocardial fibrosis
48. In vitro assessment of cardiac performance after irradiation using an isolated working rat heart preparation
49. Atrial granules contain an amino-terminal processing enzyme of atrial natriuretic factor
50. Effect of single dose of radiation on cardiac function in the rat
51. Pathologic changes in the hearts of beagles irradiated with fractionated fast neutrons or photons