Preoperative versus postoperative radiotherapy for locally advanced gastroesophageal junction and proximal gastric cancers: A comparison of normal tissue radiation doses

Diseases of the Esophagus

Volumn 21, Issue 5, 2008, Pages 437-444

  Tillman, G F ^a   Pawlicki, T ^b   Koong, A C ^c   Goodman, Karyn A ^d  

^a UMASS MEMORIAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c STANFORD UNIVERSITY   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Gastroesophageal junction tumors; IMRT; Postoperative radiation; Preoperative chemoradiation; Proximal gastric cancer

Indexed keywords

ABDOMEN; ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER LOCALIZATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOSIMETRY; ESOPHAGUS CANCER; HEART; HISTOGRAM; HUMAN; INTENSITY MODULATED RADIATION THERAPY; KIDNEY PARENCHYMA; LIVER PARENCHYMA; LOWER ESOPHAGUS SPHINCTER; LUNG PARENCHYMA; PATIENT SELECTION; POSTOPERATIVE PERIOD; PREOPERATIVE RADIOTHERAPY; PRIORITY JOURNAL; RADIATION DOSE DISTRIBUTION; SPINAL CORD; STOMACH CANCER; TREATMENT PLANNING;

ADENOCARCINOMA; AGED; ESOPHAGOGASTRIC JUNCTION; FEMALE; FOLLOW-UP STUDIES; GASTRECTOMY; HUMANS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; POSTOPERATIVE CARE; PREOPERATIVE CARE; PROBABILITY; RADIOTHERAPY DOSAGE; RADIOTHERAPY, CONFORMAL; RADIOTHERAPY, INTENSITY-MODULATED; REFERENCE VALUES; RISK ASSESSMENT; SAMPLING STUDIES; STOMACH NEOPLASMS; SURVIVAL ANALYSIS; TIME FACTORS; TREATMENT OUTCOME;

EID: 48649108137     PISSN: 11208694     EISSN: 14422050     Source Type: Journal    
DOI: 10.1111/j.1442-2050.2007.00794.x     Document Type: Article

References (31)

1. Pera M, Manterola C, Vidal O, Grande L. Epidemiology of esophageal adenocarcinoma. Surg Oncol 2005; 92: 151-9.
2. Holmes R S, Vaughan T L. Epidemiology and pathogenesis of esophageal cancer. Sem Rad Onc 2007; 17: 2-9.
3. Macdonald J S, Smalley S R, Benedetti J et al. Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction. N Engl J Med 2001; 345: 725-30.
4. Bosset J F, Gignoux M, Triboulet J P et al. Chemoradiotherapy followed by surgery compared with surgery alone in squamous-cell cancer of the esophagus. N Engl J Med 1997; 337: 161-7.
5. Burmeister B H, Smithers L, Gebski V et al. Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: A randomised controlled phase III trial. Lancet Oncol 2005; 6: 659-68.
6. Urba S G, Orringer M, Turrisi A et al. Randomized trial of preoperative chemoradiation versus surgery alone in patients with locoregional esophageal carcinoma. J Clin Oncol 2001; 19: 305-13.
7. Walsh T N, Noonan N, Hollywood D, Kelly A, Keeling N, Hennessy T P. A comparison of multimodal therapy and surgery for esophageal adenocarcinoma. N Engl J Med 1996; 335: 462-7.
8. Bains M S, Stojadinovic A, Minsky B et al. A phase II trial of preoperative combined-modality therapy for localized esophageal carcinoma: Initial results. J Thorac Cardiovasc Surg 2002; 124: 270-7.
9. Goldberg M, Farma J, Lampert C et al. Survival following intensive preoperative combined modality therapy with paclitaxel, cisplatin, 5-fluorouracil, and radiation in resectable esophageal carcinoma: A phase I report. J Thorac Cardiovasc Surg 2003; 126: 1168-73.
10. Ilson D H, Bains M, Kelsen D P et al. Phase I trial of escalating-dose irinotecan given weekly with cisplatin and concurrent radiotherapy in locally advanced esophageal cancer. J Clin Oncol 2003; 21: 2926-32.
11. Ajani J A, Mansfield P F, Janjan N et al. Multi-institutional trial of preoperative chemoradiotherapy in patients with potentially resectable gastric carcinoma. J Clin Oncol 2004; 22: 2774-80.
12. Stahl M, Stuschke M, Lehmann N et al. Chemoradiation with and without surgery in patients with locally advanced squamous cell carcinoma of the esophagus. J Clin Oncol 2005; 23: 2310-17.
13. Bedenne L, Michel P, Bouché O et al. Chemoradiation followed by surgery compared with chemoradiation alone in squamous cancer of the esophagus: FFCD 9102. J Clin Oncol 2007; 25: 1160-8.
14. Sauer R, Becker H, Hohenberger W et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 2004; 351: 1731-40.
15. Gunderson L. Adenocarcinoma of the stomach: Areas of failure in a re-operation series (second or symptomatic look) clinicopathologic correlation and implications for adjuvant therapy. Int J Radiat Oncol Biol Phys 1982; 8: 1-11.
16. Smalley S R, Gunderson L, Tepper J et al. Gastric surgical adjuvant radiotherapy consensus report: Rationale and treatment implementation. Int J Radiat Oncol Biol Phys 2002; 52: 283-93.
17. Chung H T, Shakespeare T P, Wynne C J, Lu J, Mukherjee R K, Back M F. Evaluation of a radiotherapy protocol based on INT0116 for completely resected gastric adenocarcinoma. Int J Radiat Oncol Biol Phys 2004; 59: 1446-53.
18. Kwa S L, Lebesque J V, Theuws J C et al. Radiation pneumonitis as a function of mean lung dose: An analysis of pooled data of 540 patients. Int J Radiat Oncol Biol Phys 1998; 42: 1-9.
19. Seppenwoolde Y, Lebesque J V, de Jaeger K et al. Comparing different NTCP models that predict the incidence of radiation pneumonitis. Normal tissue complication probability. Int J Radiat Oncol Biol Phys 2003; 55: 724-35.
20. Willner J, Jost A, Baier K et al. A little to a lot or a lot to a little? An analysis of pneumonitis risk from dose-Volume histogram parameters of the lung in patients with lung cancer treated with 3-D conformal radiotherapy. Strahlenther Onkol 2003; 179: 548-56.
21. Yorke E, Jackson A, Rosenzweig K et al. Dose-Volume factors contributing to the incidence of radiation pneumonitis in non-small-cell lung cancer patients treated with three-dimensional conformal radiation therapy. Int J Radiat Oncol Biol Phys 2002; 54: 329-39.
22. Schallenkamp J, Miller R, Brinkmann D et al. Incidence of radiation pneumonitis after thoracic irradiation; Dose-Volume correlates. Int J Radiat Oncol Biol Phys 2007; 67: 410-6.
23. Wang S, Liao Z, Wej X et al. Analysis of clinical and dosimetric factors associated with treatment-related pneumonitis (TRP) in patients with non-small-cell lung cancer (NSCLC) treated with concurrent chemotherapy and three-dimensional conformal radiotherapy (3D-CRT). In J Radiat Oncol Biol Phys 2006; 66: 1399-407.
24. Kong F, Hayman J, Griffith K et al. Final toxicity results of a radiation-dose escalation study in patients with non-small-cell lung cancer (NSCLC): Predictors for radiation pneumonitis and fibrosis. Int J Radiat Oncol Biol Phys 2006; 65: 1075-86.
25. Lee H K, Vaporciyan A A, Cox J D et al. Postoperative pulmonary complications after preoperative chemoradiation for esophageal carcinoma: Correlation with pulmonary dose-volume histogram parameters. Int J Radiat Oncol Biol Phys 2003; 57: 1317-22.
26. Janjan N A, Crane C, Feig B W et al. Improved overall survival among responders to preoperative chemoradiation for locally advanced rectal cancer. Am J Clin Oncol 2001; 24: 107-12.
27. Garcia-Aguilar J, Hernandez de Anda E, Sirivongs P, Lee S H, Madoff R D, Rothenberger D A. A pathologic complete response to preoperative chemoradiation is associated with lower local recurrence and improved survival in rectal cancer patients treated by mesorectal excision. Dis Colon Rectum 2003; 46: 298-304.
28. Ruo L, Tickoo S, Klimstra D S et al. Long-term prognostic significance of extent of rectal cancer response to preoperative radiation and chemotherapy. Ann Surg 2002; 236: 75-81.
29. Vecchio F M, Valentini V, Minsky B D et al. The relationship of pathologic tumor regression grade (TRG) and outcomes after preoperative therapy in rectal cancer. Int J Radiat Oncol Biol Phys 2005; 62: 752-60.
30. Guillem J G, Chessin D B, Cohen A M et al. Long-term oncologic outcome following preoperative combined modality therapy and total mesorectal excision of locally advanced rectal cancer. Ann Surg 2005; 241: 829-36.
31. Lowy A M, Mansfield P F, Leach S D, Pazdur R, Dumas P, Ajani J A. Response to neoadjuvant chemotherapy best predicts survival after curative resection of gastric cancer. Ann Surg 1999; 229: 303-8.