Influence of cross-linking agent type and chitosan content on the performance of pectinate-chitosan beads aimed for colon-specific drug delivery

Drug Development and Industrial Pharmacy

Volumn 38, Issue 9, 2012, Pages 1142-1151

  Maestrelli, F ^a   Cirri, M ^a   Mennini, N ^a   Bragagni, M ^a   Zerrouk, N ^b   Mura, P ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Ca pectinate; Theophylline; Zn pectinate

Indexed keywords

CALCIUM ION; CHITOSAN; PECTIN; THEOPHYLLINE; ZINC ION;

ARTICLE; CELL STRAIN CACO 2; CONCENTRATION (PARAMETERS); CROSS LINKING; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG RELEASE; IN VITRO STUDY; MUCOADHESION; PH; SOLID STATE;

ADHESIVENESS; CACO-2 CELLS; CALCIUM; CELL MEMBRANE PERMEABILITY; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; COLON; CROSS-LINKING REAGENTS; DRUG DELIVERY SYSTEMS; EXCIPIENTS; GASTROINTESTINAL AGENTS; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; MICROSPHERES; PECTINS; PHYSICOCHEMICAL PHENOMENA; SOLUBILITY; THEOPHYLLINE; ZINC;

EID: 84864421784     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2011.641566     Document Type: Article

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