Cigarette smoke and LDL cooperate in reducing nitric oxide bioavailability in endothelial cells via effects on both eNOS and NADPH oxidase

Nitric Oxide - Biology and Chemistry

Volumn 27, Issue 3, 2012, Pages 176-184

  Steffen, Yvonne ^a   Vuillaume, Gregory ^b   Stolle, Katrin ^a   Roewer, Karin ^a   Lietz, Michael ^a   Schueller, Jutta ^a   Lebrun, Stefan ^b   Wallerath, Thomas ^a  

^a Philip Morris Research Laboratories GmbH   (Germany)

^b PHILIP MORRIS PRODUCTS S A   (Switzerland)

Author keywords

Cigarette smoke; Endothelial cell; LDL; Nitric oxide; Oxidative stress

Indexed keywords

7 OXOCHOLESTEROL; CIGARETTE SMOKE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; OXIDIZED LOW DENSITY LIPOPROTEIN; PEROXYNITRITE; PHOSPHATE BUFFERED SALINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE;

ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; UMBILICAL VEIN ENDOTHELIAL CELL;

BIOLOGICAL AVAILABILITY; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LIPOPROTEINS, LDL; MALE; NADPH OXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PEROXYNITROUS ACID; RNA, MESSENGER; RNA, SMALL INTERFERING; TOBACCO SMOKE POLLUTION; TYROSINE;

EID: 84864418766     PISSN: 10898603     EISSN: 10898611     Source Type: Journal    
DOI: 10.1016/j.niox.2012.06.006     Document Type: Article

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