Synthesis and antitumor activity of formononetin nitrogen mustard derivatives

European Journal of Medicinal Chemistry

Volumn 54, Issue , 2012, Pages 175-187

  Ren, Jie ^a   Xu, Hua Jin ^a   Cheng, Hong ^a   Xin, Wen Qun ^a   Chen, Xin ^a   Hu, Kun ^a  

^a CHANGZHOU UNIVERSITY   (China)

Author keywords

Apoptosis; Cell cycle; Cytotoxicity; Formononetin; Nitrogen mustard; Synthesis

Indexed keywords

7 (2 METHYLALLYLOXY) 3 (3 AMINO 4 METHOXYPHENYL) 4H CHROMEN 4 ONE; 7 (2 METHYLALLYLOXY) 3 (4 METHOXY 3 NITROPHENYL) 4H CHROMEN 4 ONE; 7 (3 METHYLBUT 2 ENYLOXY) 3 (3 AMINO 4 METHOXYPHENYL) 4H CHROMEN 4 ONE; 7 (3 METHYLBUT 2 ENYLOXY) 3 (4 METHOXY 3 NITROPHENYL) 4H CHROMEN 4 ONE; 7 (4 METHYLBENZYLOXY) 3 (3 AMINO 4 METHOXYPHENYL) 4H CHROMEN 4 ONE; 7 (4 METHYLBENZYLOXY) 3 (4 METHOXY 3 NITROPHENYL) 4H CHROMEN 4 ONE; 7 (BENZYLOXY) 3 (3 AMINO 4 METHOXYPHENYL) 4H CHROMEN 4 ONE; 7 (CYCLOPENTYLOXY) 3 (4 METHOXY 3 NITROPHENYL) 4H CHROMEN 4 ONE; 7 (PENTAN 2 YLOXY) 3 (3 AMINO 4 METHOXYPHENYL) 4H CHROMEN 4 ONE; 7 (PENTAN 2 YLOXY) 3 (4 METHOXY 3 NITROPHENYL) 4H CHROMEN 4 ONE; 7 ALLYLOXY 3 (3 AMINO 4 METHOXYPHENYL) 4H CHROMEN 4 ONE; 7 ALLYLOXY 3 (4 METHOXY 3 NITROPHENYL) 4H CHROMEN 4 ONE; 7 BENZYLOXY 3 (4 METHOXY 3 NITROPHENYL) 4H CHROMEN 4 ONE; 7 BUTOXY 3 (3 AMINO 4 METHOXYPHENYL) 4H CHROMEN 4 ONE; 7 BUTOXY 3 (4 METHOXY 3 NITROPHENYL) 4H CHROMEN 4 ONE; 7 ETHOXY 3 (3 AMINO 4 METHOXYPHENYL) 4H CHROMEN 4 ONE; 7 ETHOXY 3 (4 METHOXY 3 NITROPHENYL) 4H CHROMEN 4 ONE; 7 ISOPROPOXY 3 (3 AMINO 4 METHOXYPHENYL) 4H CHROMEN 4 ONE; 7 ISOPROPOXY 3 (4 METHOXY 3 NITROPHENYL) 4H CHROMEN 4 ONE; 7 PHENETHOXY 3 (3 AMINO 4 METHOXYPHENYL) 4H CHROMEN 4 ONE; 7 PHENETHOXY 3 (4 METHOXY 3 NITROPHENYL) 4H CHROMEN 4 ONE; 7 PROPOXY 3 (3 AMINO 4 METHOXYPHENYL) 4H CHROMEN 4 ONE; 7 PROPOXY 3 (4 METHOXY 3 NITROPHENYL) 4H CHROMEN 4 ONE; 7 SEC BUTOXY 3 (3 AMINO 4 METHOXYPHENYL) 4H CHROMEN 4 ONE; 7 SEC BUTOXY 3 (4 METHOXY 3 NITROPHENYL) 4H CHROMEN 4 ONE; ANTINEOPLASTIC AGENT; CHLORMETHINE DERIVATIVE; FORMONONETIN; MELPHALAN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IN VITRO STUDY; M PHASE CELL CYCLE CHECKPOINT; THERAPY EFFECT;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CHEMISTRY TECHNIQUES, SYNTHETIC; HUMANS; INHIBITORY CONCENTRATION 50; ISOFLAVONES; MECHLORETHAMINE;

EID: 84864416212     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.04.039     Document Type: Article

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