Evaluation of the procoagulant activity of endogenous phospholipids in the platelet-free plasma of children with sickle cell disease using functional assays

Thrombosis Research

Volumn 130, Issue 2, 2012, Pages 259-264

  Noubouossie, Denis C F ^a   Lê, Phu Quoc ^b   Rozen, Laurence ^a   Debaugnies, France ^a   Ferster, Alina ^b   Demulder, Anne ^a  

^a BRUGMANN UNIVERSITY HOSPITAL   (Belgium)

^b HOP UNIV DES ENFANTS REINE FABIOLA   (Belgium)

Author keywords

Clotting time; Microparticles; Phospholipids; Procoagulant activity; Sickle; Thrombin generation

Indexed keywords

BLOOD CLOTTING FACTOR 10A; HYDROXYUREA; PHOSPHOLIPID; THROMBIN; THROMBOPLASTIN; PROCOAGULANT;

ADOLESCENT; ADULT; ARTICLE; BLOOD CLOTTING; BLOOD CLOTTING TIME; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; EXCHANGE BLOOD TRANSFUSION; FEMALE; HUMAN; HUMAN TISSUE; MALE; MEMBRANE MICROPARTICLE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SICKLE CELL ANEMIA; VEIN OCCLUSION; COMPARATIVE STUDY; HEMOSTASIS; PARAMETERS; STEADY STATE; THROMBIN TIME; THROMBOCYTE FREE PLASMA; THROMBOSIS; BLOOD; BLOOD CLOTTING TEST; METABOLISM; THROMBOPHILIA;

ADOLESCENT; ADULT; ANEMIA, SICKLE CELL; BLOOD COAGULATION TESTS; CELL-DERIVED MICROPARTICLES; CHILD; CHILD, PRESCHOOL; FACTOR XA; FEMALE; HUMANS; MALE; PHOSPHOLIPIDS; THROMBIN; THROMBOPHILIA; YOUNG ADULT;

EID: 84864411805     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2011.10.016     Document Type: Article

References (29)

1. M.T. Gladwin, and G.J. Kato Hemolysis-associated hypercoagulability in sickle cell disease: the plot (and blood) thickens! Haematologica 93 2008 1 3 (Pubitemid 351156142)
2. M.J. Stuart, and B.N. Setty Hemostatic alterations in sickle cell disease: relationships to disease pathophysiology Pediatr Pathol Mol Med 20 2001 27 46 (Pubitemid 32168001)
3. K.I. Ataga Hypercoagulability and thrombotic complications in hemolytic anemias Haematologica 94 2009 1481 1484
4. S.T. Singer, and K.I. Ataga Hypercoagulability in sickle cell disease and beta-thalassemia Curr Mol Med 8 2008 639 645
5. K.I. Ataga, and E.P. Orringer Hypercoagulability in sickle cell disease: a curious paradox Am J Med 115 2003 721 728 (Pubitemid 38032666)
6. K.I. Ataga, and N.S. Key Hypercoagulability in sickle cell disease: new approaches to an old problem Hematology Am Soc Hematol Educ Program 2007 91 96
7. F.A. Kuypers, R.A. Lewis, M. Hua, M.A. Schott, D. Discher, and J.D. Ernst Detection of altered membrane phospholipid asymmetry in subpopulations of human red blood cells using fluorescently labeled annexin V Blood 87 1996 1179 1187 (Pubitemid 26043547)
8. B.L. Wood, D.F. Gibson, and J.F. Tait Increased erythrocyte phosphatidylserine exposure in sickle cell disease: flow-cytometric measurement and clinical associations Blood 88 1996 1873 1880 (Pubitemid 26307087)
9. E.J. van Beers, M.C.L. Schaap, R.J. Berckmans, R. Nieuwland, A. Sturk, and F.F. van Doormaal Circulating erythrocyte-derived microparticles are associated with coagulation activation in sickle cell disease Haematologica 94 2009 1513 1519
10. M. Westerman, A. Pizzey, J. Hirschman, M. Cerino, Y. Weil-Weiner, and P. Ramotar Microvesicles in haemoglobinopathies offer insights into mechanisms of hypercoagulability, haemolysis and the effects of therapy Br J Haematol 142 2008 126 135 (Pubitemid 351783151)
11. L.J. van Tits, W.L. van Heerde, P.P. Landburg, M.J. Boderie, F.A.J. Muskiet, and N. Jacobs Plasma annexin A5 and microparticle phosphatidylserine levels are elevated in sickle cell disease and increase further during painful crisis Biochem Biophys Res Commun 390 2009 161 164
12. A.S. Shet, O. Aras, K. Gupta, M.J. Hass, D.J. Rausch, and N. Saba Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes Blood 102 2003 2678 2683 (Pubitemid 37193612)
13. T. Exner, J. Joseph, J. Low, D. Connor, and D. Ma A new activated factor X-based clotting method with improved specificity for procoagulant phospholipid Blood Coagul Fibrinolysis 14 2003 773 779
14. H.C. Hemker, P. Giesen, R. Al Dieri, V. Regnault, E. de Smedt, and R. Wagenvoord Calibrated automated thrombin generation measurement in clotting plasma Pathophysiol Haemost Thromb 33 2003 4 15 (Pubitemid 37449290)
15. P. van Dreden, A. Rousseau, S. Fontaine, B.J. Woodhams, and T. Exner Clinical evaluation of a new functional test for detection of plasma procoagulant phospholipids Blood Coagul Fibrinolysis 20 2009 494 502
16. T. Exner, J.E. Joseph, D. Connor, J. Low, and D.D.F. Ma Increased procoagulant phospholipid activity in blood from patients with suspected acute coronary syndromes: a pilot study Blood Coagul Fibrinolysis 16 2005 375 379 (Pubitemid 41008746)
17. F. Debaugnies, M.-A. Azerad, D. Noubouossié, L. Rozen, H.C. Hemker, and F. Corazza Evaluation of the procoagulant activity in the plasma of cancer patients using a thrombin generation assay Thromb Res 126 2010 531 535
18. B.A.L. Owen, A. Xue, J.A. Heit, and W.G. Owen Procoagulant activity, but not number, of microparticles increases with age and in individuals after a single venous thromboembolism Thromb Res 127 2011 39 46
19. O.S. Platt Sickle cell anemia as an inflammatory disease J Clin Invest 106 2000 337 338 (Pubitemid 30655633)
20. J.J. van Veen, A. Gatt, P.C. Cooper, S. Kitchen, A.E. Bowyer, and M. Makris Corn trypsin inhibitor in fluorogenic thrombin-generation measurements is only necessary at low tissue factor concentrations and influences the relationship between factor VIII coagulant activity and thrombogram parameters Blood Coagul Fibrinolysis 19 2008 183 189 (Pubitemid 351498720)
21. T.M. Hackeng, L.F.A. Maurissen, E. Castoldi, and J. Rosing Regulation of TFPI function by protein S J Thromb Haemost 7 S1 2009 165 168
22. E. Castoldi, P. Simioni, D. Tormene, J. Rosing, and T.M. Hackeng Hereditary and acquired protein S deficiencies are associated with low TFPI levels in plasma J Thromb Haemost 8 2010 294 300
23. G.T. Gerotziafas, F. Depasse, J. Busson, L. Leflem, I. Elalamy, and M.M. Samama Towards a standardization of thrombin generation assessment: The influence of tissue factor, platelets and phospholipids concentration on the normal values of Thrombogram-Thrombinoscope assay Thromb J 3 2005 16-16
24. W. Jy, L.L. Horstman, J.J. Jimenez, Y.S. Ahn, E. Biró, and R. Nieuwland Measuring circulating cell-derived microparticles J Thromb Haemost 2 2004 1842 1851 (Pubitemid 40197488)
25. R. Lacroix, S. Robert, P. Poncelet, and F. Dignat-George Overcoming limitations of microparticle measurement by flow cytometry Semin Thromb Hemost 36 2010 807 818
26. M.P. Westerman, D. Green, A. Gilman-Sachs, K. Beaman, S. Freels, and L. Boggio Antiphospholipid antibodies, proteins C and S, and coagulation changes in sickle cell disease J Lab Clin Med 134 1999 352 362 (Pubitemid 29490154)
27. M.P. Westerman, D. Green, A. Gilman-Sachs, K. Beaman, S. Freels, and L. Boggio Coagulation changes in individuals with sickle cell trait Am J Hematol 69 2002 89 94 (Pubitemid 34111159)
28. R.G. Steen, T. Emudianughe, G.M. Hankins, L.W. Wynn, W.C. Wang, and X. Xiong Brain imaging findings in pediatric patients with sickle cell disease Radiology 228 2003 216 225 (Pubitemid 36736094)
29. P. Telfer, P. Coen, S. Chakravorty, O. Wilkey, J. Evans, and H. Newell Clinical outcomes in children with sickle cell disease living in England: a neonatal cohort in East London Haematologica 92 2007 905 912 (Pubitemid 350144237)