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European Journal of Medicinal Chemistry

Volumn 54, Issue , 2012, Pages 925-930

Synthesis and antitumor activity of novel quinazoline derivatives containing thiosemicarbazide moiety

(6) He, Junbo a Wang, Xiaoguo a Zhao, Xiaoqin b Liang, Yongju b He, Hongwu a Fu, Liwu b

a CENTRAL CHINA NORMAL UNIVERSITY (China)

b SUN YAT SEN UNIVERSITY CANCER CENTER (China)

Author keywords

Antitumor activity; Quinazoline; Synthesis; Thiosemicarbazide

Indexed keywords

2 CHLORO N [2 (6,7 DIMETHOXYQUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL]BENZAMIDE; 2 CHLORO N [2 (QUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL]BENZAMIDE; 2 FLUORO N [2 (QUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL]BENZAMIDE; 2 METHOXY N [2 (QUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL]BENZAMIDE; 2 METHYL N [2 (QUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL]BENZAMIDE; 3 CHLORO N [2 (6,7 DIMETHOXYQUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL]BENZAMIDE; 3 CHLORO N [2 (QUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL]BENZAMIDE; 4 CHLORO N [2 (6,7 DIMETHOXYQUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL]BENZAMIDE; 4 CHLORO N [2 (QUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL]BENZAMIDE; 4 FLUORO N [2 (QUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL]BENZAMIDE; 4 METHYL N [2 (QUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL]BENZAMIDE; ANTINEOPLASTIC AGENT; FLUOROURACIL; N [2 (6,7 DIMETHOXYQUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL] 2 FLUOROBENZAMIDE; N [2 (6,7 DIMETHOXYQUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL] 2 METHYLBENZAMIDE; N [2 (6,7 DIMETHOXYQUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL] 4 (TRIFLUOROMETHYL)BENZAMIDE; N [2 (6,7 DIMETHOXYQUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL] 4 FLUOROBENZAMIDE; N [2 (6,7 DIMETHOXYQUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL] 4 METHYLBENZAMIDE; N [2 (6,7 DIMETHOXYQUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL]BENZAMIDE; N [2 (QUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL] 4 (TRIFLUOROMETHYL)BENZAMIDE; N [2 (QUINAZOLIN 4 YL)HYDRAZINECARBONOTHIOYL]BENZAMIDE; QUINAZOLINE DERIVATIVE; THIOSEMICARBAZIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CONTROLLED STUDY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHEMISTRY TECHNIQUES, SYNTHETIC; HUMANS; INHIBITORY CONCENTRATION 50; QUINAZOLINES; SEMICARBAZIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84864409779 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2012.06.003 Document Type: Article

Times cited : (73)

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