메뉴 건너뛰기




Volumn 1, Issue 4, 2007, Pages 335-346

Review of erlotinib in the treatment of advanced non-small cell lung cancer

Author keywords

Epidermal growth factor receptor; Erlotinib; Non small cell lung cancer

Indexed keywords


EID: 63149090545     PISSN: 11775475     EISSN: 11775491     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (64)

References (78)
  • 1
    • 33847091172 scopus 로고    scopus 로고
    • EGFR, ERBB2, and KRAS mutations in Korean non-small cell lung cancer patients
    • Bae NC, Chae MH, Lee MH, et al. 2007. EGFR, ERBB2, and KRAS mutations in Korean non-small cell lung cancer patients. Cancer Genet Cytogenet, 173:107-13.
    • (2007) Cancer Genet Cytogenet , vol.173 , pp. 107-113
    • Bae, N.C.1    Chae, M.H.2    Lee, M.H.3
  • 2
    • 0002145419 scopus 로고    scopus 로고
    • New technologies in epidermal growth factor receptortargeted cancer therapy:An overview of novel therapeutic agents in development
    • Baselga J. 2000. New technologies in epidermal growth factor receptortargeted cancer therapy:an overview of novel therapeutic agents in development. Signal, 1:12-21.
    • (2000) Signal , vol.1 , pp. 12-21
    • Baselga, J.1
  • 3
    • 33748445361 scopus 로고    scopus 로고
    • Symptom improvement in lung cancer patients treated with erlotinib:Quality of life analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21
    • Bezjak A, Tu D, Seymour L, et al. 2006. Symptom improvement in lung cancer patients treated with erlotinib:quality of life analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21. J Clin Oncol, 24:3831-7.
    • (2006) J Clin Oncol , vol.24 , pp. 3831-3837
    • Bezjak, A.1    Tu, D.2    Seymour, L.3
  • 4
    • 10444220480 scopus 로고    scopus 로고
    • Cetuximab prolongs survival in patients with locoregionally advanced squamous cell carcinoma of head and neck:A phase III study of high dose radiation therapy with or without cetuximab
    • Bonner JA, Harari PM, Giralt J, et al. 2004. Cetuximab prolongs survival in patients with locoregionally advanced squamous cell carcinoma of head and neck:A phase III study of high dose radiation therapy with or without cetuximab. Proc Am Soc Clin Oncol, 23:5507.
    • (2004) Proc Am Soc Clin Oncol , vol.23 , pp. 5507
    • Bonner, J.A.1    Harari, P.M.2    Giralt, J.3
  • 5
    • 33745683527 scopus 로고    scopus 로고
    • Biological markers for non-small cell lung cancer patient selection for epidermal growth factor receptor tyrosine kinase inhibitor therapy
    • Bunn PA, Dziadziuszko R, Varella-Garcia M, et al. 2002. Biological markers for non-small cell lung cancer patient selection for epidermal growth factor receptor tyrosine kinase inhibitor therapy. Clin Cancer Res, 12:3652-6.
    • (2002) Clin Cancer Res , vol.12 , pp. 3652-3656
    • Bunn, P.A.1    Dziadziuszko, R.2    Varella-Garcia, M.3
  • 6
    • 34250161814 scopus 로고    scopus 로고
    • Prospective study of gefitinib in epidermal growth factor receptor fluorescence in situ hybridization-positive/phosphor-Akt-positive or never smoker patients with advanced non-small cell lung cancer: The ONCOBELL trial
    • Cappuzzo F, Ligorio C, Janne P, et al. 2007. Prospective study of gefitinib in epidermal growth factor receptor fluorescence in situ hybridization-positive/phosphor-Akt-positive or never smoker patients with advanced non-small cell lung cancer: The ONCOBELL trial. J Clin Oncol, 25:2248-55.
    • (2007) J Clin Oncol , vol.25 , pp. 2248-2255
    • Cappuzzo, F.1    Ligorio, C.2    Janne, P.3
  • 7
    • 20444498630 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small cell lung cancer
    • Cappuzzo F, Hirsch FR, Rossi E, et al. 2005. Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small cell lung cancer. J Natl Cancer Inst, 97:643-55.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 643-655
    • Cappuzzo, F.1    Hirsch, F.R.2    Rossi, E.3
  • 8
    • 0032881288 scopus 로고    scopus 로고
    • AKT/PKB and other D3 phosphoinositide-regulated kinases: Kinase activation by phosphoinositide-dependent phosphorylation
    • Chan TO, Rittenhouse SE, Tsichlis PN. 1999. AKT/PKB and other D3 phosphoinositide-regulated kinases: Kinase activation by phosphoinositide-dependent phosphorylation. Ann Rev Biochem, 68:965-1014.
    • (1999) Ann Rev Biochem , vol.68 , pp. 965-1014
    • Chan, T.O.1    Rittenhouse, S.E.2    Tsichlis, P.N.3
  • 9
    • 0034799139 scopus 로고    scopus 로고
    • A novel approach in the treatment of cancer: Targeting the epidermal growth factor receptor
    • Ciardiello F, Tortora G. 2001. A novel approach in the treatment of cancer: Targeting the epidermal growth factor receptor. Clin Cancer Res, 7:2958-70.
    • (2001) Clin Cancer Res , vol.7 , pp. 2958-2970
    • Ciardiello, F.1    Tortora, G.2
  • 10
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D, Humblet Y, Siena S, et al. 2004. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med, 351:337-45.
    • (2004) N Engl J Med , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 11
    • 34248186584 scopus 로고    scopus 로고
    • Predicting gefitinib responsiveness in lung cancer by fluorescence in situ hybridization /chromogenic in situ hybridization analysis of EGFR and HER2 in biopsy and cytology specimens
    • Daniele L, Macri L, Schena M, et al. 2007. Predicting gefitinib responsiveness in lung cancer by fluorescence in situ hybridization /chromogenic in situ hybridization analysis of EGFR and HER2 in biopsy and cytology specimens. Mol Cancer Ther, 6:1223-9.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1223-1229
    • Daniele, L.1    Macri, L.2    Schena, M.3
  • 12
    • 57649127564 scopus 로고    scopus 로고
    • Pharmacodynamic separation of erlotinib and docetaxel (DOC) in advanced non-small cell lung cancer (NSCLC):Overcoming hypothesized antagonism
    • 18S:abst# 7618
    • Davies AM, Hesketh PJ, Beckett L, et al. 2007. Pharmacodynamic separation of erlotinib and docetaxel (DOC) in advanced non-small cell lung cancer (NSCLC):Overcoming hypothesized antagonism. J Clin Oncol, Proc ASCO, 25, 18S:abst# 7618.
    • (2007) J Clin Oncol, Proc ASCO , vol.25
    • Davies, A.M.1    Hesketh, P.J.2    Beckett, L.3
  • 13
    • 31344439682 scopus 로고    scopus 로고
    • Intermittent erlotinib in combination with docetaxel (DOC):Phase I schedules designed to schieve pharmacodynamic separation
    • 16S: abst# 7038
    • Davies AM, Lara PN, Lau DH, et al. 2005. Intermittent erlotinib in combination with docetaxel (DOC):Phase I schedules designed to schieve pharmacodynamic separation. J Clin Oncol, Proc ASCO, 23, 16S: abst# 7038.
    • (2005) J Clin Oncol, Proc ASCO , vol.23
    • Davies, A.M.1    Lara, P.N.2    Lau, D.H.3
  • 14
    • 3242803674 scopus 로고    scopus 로고
    • Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small cell lung cancer
    • Delbaldo C, Michiels S, Syz N, et al. 2004. Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small cell lung cancer. JAMA, 292:470-84.
    • (2004) JAMA , vol.292 , pp. 470-484
    • Delbaldo, C.1    Michiels, S.2    Syz, N.3
  • 15
    • 24944497744 scopus 로고    scopus 로고
    • Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small cell lung cancer treated with chemotherapy alone and in combination with erlotinib
    • Eberhard DA, Johnson BE, Amler LC, et al. 2005. Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small cell lung cancer treated with chemotherapy alone and in combination with erlotinib. J Clin Oncol, 23:5900-9.
    • (2005) J Clin Oncol , vol.23 , pp. 5900-5909
    • Eberhard, D.A.1    Johnson, B.E.2    Amler, L.C.3
  • 16
    • 0035102719 scopus 로고    scopus 로고
    • CYP3A genetics in drug metabolism
    • Eichelbaum M, Burk O. 2001. CYP3A genetics in drug metabolism. Nature Med, 7:285-7.
    • (2001) Nature Med , vol.7 , pp. 285-287
    • Eichelbaum, M.1    Burk, O.2
  • 17
    • 0027530832 scopus 로고
    • Effects of EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratory and invasive capacities of human brain-tumor biopsies in vitro
    • Engebraaten O, Bjerkvig R, Pedersen PH, et al. 1993. Effects of EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratory and invasive capacities of human brain-tumor biopsies in vitro. Int J Cancer, 53:209-14.
    • (1993) Int J Cancer , vol.53 , pp. 209-214
    • Engebraaten, O.1    Bjerkvig, R.2    Pedersen, P.H.3
  • 18
    • 34249075147 scopus 로고    scopus 로고
    • MET amplification leads to gefitinib resistance in lung cancer by activationg ERBB3 signaling
    • 1093-1043
    • Engelman JA, Zejnullahu K, Mitsudomi T, et al. 2007. MET amplification leads to gefitinib resistance in lung cancer by activationg ERBB3 signaling. Science, 316:1093-43.
    • (2007) Science , vol.316
    • Engelman, J.A.1    Zejnullahu, K.2    Mitsudomi, T.3
  • 19
    • 36849007958 scopus 로고    scopus 로고
    • Phase III study of immediate versus delayed docetaxel after induction therapy with gemcitabine plus carboplatin in advanced non-small cell lung cancer:Updated report with survival
    • No, 18S:abst# LBA7516
    • Fidias P, Dakhil S, Lyss A, et al. 2007. Phase III study of immediate versus delayed docetaxel after induction therapy with gemcitabine plus carboplatin in advanced non-small cell lung cancer:Updated report with survival. J of Clin Oncol, ASCO Proc, 25, No. 18S:abst# LBA7516.
    • (2007) J of Clin Oncol, ASCO Proc , vol.25
    • Fidias, P.1    Dakhil, S.2    Lyss, A.3
  • 20
    • 0034095853 scopus 로고    scopus 로고
    • Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small cell lung cancer previously treated with platinum-containing chemotherapy regimens
    • Fossella F, DeVore R, Kerr R, et al. 2000. Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small cell lung cancer previously treated with platinum-containing chemotherapy regimens. J Clin Oncol, 18:2354-62.
    • (2000) J Clin Oncol , vol.18 , pp. 2354-2362
    • Fossella, F.1    Devore, R.2    Kerr, R.3
  • 21
    • 0036118262 scopus 로고    scopus 로고
    • Epidermal growth factor receptor family in lung cancer and premalignancy
    • Franklin WA, Veve R, Hirsch FR, et al. 2002. Epidermal growth factor receptor family in lung cancer and premalignancy. Semin Oncol, 29(Suppl 4):3-14.
    • (2002) Semin Oncol , vol.29 , Issue.SUPPL. 4 , pp. 3-14
    • Franklin, W.A.1    Veve, R.2    Hirsch, F.R.3
  • 22
    • 0012381722 scopus 로고    scopus 로고
    • Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small cell lung cancer (The IDEAL 1 Trial) corrected
    • Fukuoka M, Yano S, Giaccone G, et al. 2003. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small cell lung cancer (The IDEAL 1 Trial) corrected. J Clin Oncol, 21:2237-46.
    • (2003) J Clin Oncol , vol.21 , pp. 2237-2246
    • Fukuoka, M.1    Yano, S.2    Giaccone, G.3
  • 23
    • 51349083228 scopus 로고    scopus 로고
    • Erlotinib in non-small cell lung cancer (NSCLC):Interim safety analysis of the TRUST study
    • a, 18S:abstr# 7645
    • Gatzemeier U, Ardizzoni A, Horwood K, et al. 2007a. Erlotinib in non-small cell lung cancer (NSCLC):Interim safety analysis of the TRUST study. J Clin Oncol, Proc ASCO, 25, 18S:abstr# 7645.
    • (2007) J Clin Oncol, Proc ASCO , vol.25
    • Gatzemeier, U.1    Ardizzoni, A.2    Horwood, K.3
  • 24
    • 34248140107 scopus 로고    scopus 로고
    • Phase III study of Erlotinib in Combination With Cisplatin and Gemcitabine in Advanced non-small cell Lung Cancer: The Tarceva Lung Cancer Investigation Trial
    • Gatzemeier U, Pluzanska A, Szczesna A, et al. 2007b. Phase III study of Erlotinib in Combination With Cisplatin and Gemcitabine in Advanced non-small cell Lung Cancer: The Tarceva Lung Cancer Investigation Trial. J Clin Oncol, 25:1545-52.
    • (2007) J Clin Oncol , vol.25 , pp. 1545-1552
    • Gatzemeier, U.1    Pluzanska, A.2    Szczesna, A.3
  • 25
    • 1542503746 scopus 로고    scopus 로고
    • Gefitinib in combination with gemcitabine and cisplatin in advanced non-small cell lung cancer: A phase III trial-INTACT 1
    • Giaconne G, Herbst RS, Manegold C, et al. 2004. Gefitinib in combination with gemcitabine and cisplatin in advanced non-small cell lung cancer: a phase III trial-INTACT 1. J Clin Oncol, 22:777-84.
    • (2004) J Clin Oncol , vol.22 , pp. 777-784
    • Giaconne, G.1    Herbst, R.S.2    Manegold, C.3
  • 26
    • 33750700477 scopus 로고    scopus 로고
    • Erlotinib for frontline treatment of advanced non-small cell lung cancer:A phase II study
    • Giaccone G, Gallegos Ruiz M, Le Chevalier T, et al. 2006. Erlotinib for frontline treatment of advanced non-small cell lung cancer:a phase II study. Clin Cancer Res, 12:6049-55.
    • (2006) Clin Cancer Res , vol.12 , pp. 6049-6055
    • Giaccone, G.1    Gallegos R., M.2    le Chevalier, T.3
  • 27
    • 0021254542 scopus 로고
    • Monoclonal antiepidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factorstimulated tyrosine protein kinase activity
    • Gill GN, Kawamoto T, Cochet C, et al. 1984. Monoclonal antiepidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factorstimulated tyrosine protein kinase activity. J Biol Chem, 259:7755-60.
    • (1984) J Biol Chem , vol.259 , pp. 7755-7760
    • Gill, G.N.1    Kawamoto, T.2    Cochet, C.3
  • 29
    • 2442523996 scopus 로고    scopus 로고
    • Enhanced cytotoxicity of docetaxel OSI-774 combination in non-small cell lung cancer (NSCLC)
    • 22:abst# 2661
    • Gumerlock PH, Pryde BJ, Kimura T, et al. 2003. Enhanced cytotoxicity of docetaxel OSI-774 combination in non-small cell lung cancer (NSCLC). J Clin Oncol, Proc ASCO, 22:abst# 2661.
    • (2003) J Clin Oncol, Proc ASCO
    • Gumerlock, P.H.1    Pryde, B.J.2    Kimura, T.3
  • 30
    • 2442661845 scopus 로고    scopus 로고
    • Randomized phase iii trial of pemetrexed versus docetaxel in patients with non-small cell lung cancer previously treated with chemotherapy
    • Hanna N, Shepherd FA, Fossella FV, et al. 2004. Randomized phase iii trial of pemetrexed versus docetaxel in patients with non-small cell lung cancer previously treated with chemotherapy. J Clin Oncol, 22:1589-97.
    • (2004) J Clin Oncol , vol.22 , pp. 1589-1597
    • Hanna, N.1    Shepherd, F.A.2    Fossella, F.V.3
  • 31
    • 24944440830 scopus 로고    scopus 로고
    • TRIBUTE:A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small cell lung cancer
    • a
    • Herbst RS, Prager D, Hermann R, et al. 2005a. TRIBUTE:a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small cell lung cancer. J Clin Oncol, 23:5892-9.
    • (2005) J Clin Oncol , vol.23 , pp. 5892-5899
    • Herbst, R.S.1    Prager, D.2    Hermann, R.3
  • 32
    • 20244381389 scopus 로고    scopus 로고
    • Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small cell lung cancer
    • Herbst RS, Johnson DH, Mininberg E, et al. 2005b. Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small cell lung cancer. J Clin Oncol, 23:2544-55.
    • (2005) J Clin Oncol , vol.23 , pp. 2544-2555
    • Herbst, R.S.1    Johnson, D.H.2    Mininberg, E.3
  • 33
    • 2342492317 scopus 로고    scopus 로고
    • Review of epidermal growth factor receptor biology
    • Herbst RS. 2004. Review of epidermal growth factor receptor biology. Int J Radiat Oncol Biol Phys, 59:21-6,
    • (2004) Int J Radiat Oncol Biol Phys , vol.59 , pp. 21-26
    • Herbst, R.S.1
  • 34
    • 0035398631 scopus 로고    scopus 로고
    • Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies
    • Hidalgo M, Siu LL, Nemunaitis J, et al. 2001. Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies. J Clin Oncol, 19:3267-79.
    • (2001) J Clin Oncol , vol.19 , pp. 3267-3279
    • Hidalgo, M.1    Siu, L.L.2    Nemunaitis, J.3
  • 35
    • 0036570203 scopus 로고    scopus 로고
    • ZD1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase
    • Hirata A,Ogawa S, Kometani T, et al. 2002. ZD1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase. Cancer Res, 62:2554-60.
    • (2002) Cancer Res , vol.62 , pp. 2554-2560
    • Hirata, A.1    Ogawa, S.2    Kometani, T.3
  • 36
    • 34047132314 scopus 로고    scopus 로고
    • Combination of EGFR gene copy number and protein expression predicts outcome for advanced non-small cell lung cancer patients treated with gefitinib
    • Hirsch FR, Varella-Garcia M, Cappuzzo F, et al. 2007. Combination of EGFR gene copy number and protein expression predicts outcome for advanced non-small cell lung cancer patients treated with gefitinib. Ann Oncol, 18:752-60.
    • (2007) Ann Oncol , vol.18 , pp. 752-760
    • Hirsch, F.R.1    Varella-Garcia, M.2    Cappuzzo, F.3
  • 37
    • 0142119289 scopus 로고    scopus 로고
    • Epidermal growth factor receptor in non-small cell lung carcinomas:Correlation between gene copy number and protein expression and impact on prognosis
    • Hirsch FR, Varella-Garcia M, Bunn PA, et al. 2003. Epidermal growth factor receptor in non-small cell lung carcinomas:correlation between gene copy number and protein expression and impact on prognosis. J Clin Oncol, 21:3798-807.
    • (2003) J Clin Oncol , vol.21 , pp. 3798-3807
    • Hirsch, F.R.1    Varella-Garcia, M.2    Bunn, P.A.3
  • 38
    • 33746789922 scopus 로고    scopus 로고
    • Prospective phase II study of gefitinib for chemotherapy-naïve patients with advanced non-small cell lung cancer with epidermal growth factor receptor gene mutation
    • Inoue A, Suzuki T, Fukuhara T, et al. 2006. Prospective phase II study of gefitinib for chemotherapy-naïve patients with advanced non-small cell lung cancer with epidermal growth factor receptor gene mutation. J Clin Oncol, 24:3340-6.
    • (2006) J Clin Oncol , vol.24 , pp. 3340-3346
    • Inoue, A.1    Suzuki, T.2    Fukuhara, T.3
  • 39
    • 33947504732 scopus 로고    scopus 로고
    • Phase II clinical trial of chemotherapy-naive patients or = 70 years of age treated with erlotinib for advanced non-small cell lung cancer
    • Jackman DM, Yeap BY, Lindeman NI, et al. 2007. Phase II clinical trial of chemotherapy-naive patients or = 70 years of age treated with erlotinib for advanced non-small cell lung cancer. J Clin Oncol, 25:760-6.
    • (2007) J Clin Oncol , vol.25 , pp. 760-766
    • Jackman, D.M.1    Yeap, B.Y.2    Lindeman, N.I.3
  • 40
    • 33746034167 scopus 로고    scopus 로고
    • Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib
    • Jackman DM, Yeap BY, Sequist LV, et al. 2006. Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib. Clin Cancer Res, 12:3908-14.
    • (2006) Clin Cancer Res , vol.12 , pp. 3908-3914
    • Jackman, D.M.1    Yeap, B.Y.2    Sequist, L.V.3
  • 41
    • 19844375720 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations in non-small cell lung cancer:Implications for treatment and tumor biology
    • Janne PA, Engelman JA, and Johnson BE. 2005. Epidermal growth factor receptor mutations in non-small cell lung cancer:Implications for treatment and tumor biology. J Clin Oncol, 23:3227-34.
    • (2005) J Clin Oncol , vol.23 , pp. 3227-3234
    • Janne, P.A.1    Engelman, J.A.2    Johnson, B.E.3
  • 42
    • 61449128170 scopus 로고    scopus 로고
    • Does tetracycline prevent/palliate epidermal growth factor receptor (EGFR) inhibitor-induced rash? A phase III trial from the North Central Cancer Treatment Group (N03CB)
    • 18S:abst# LBA9006
    • Jatoi A, Rowland K, Sloan JA, et al. 2007. Does tetracycline prevent/palliate epidermal growth factor receptor (EGFR) inhibitor-induced rash? A phase III trial from the North Central Cancer Treatment Group (N03CB). J Clin Oncol, Proc ASCO, 25, 18S:abst# LBA9006.
    • (2007) J Clin Oncol, Proc ASCO , vol.25
    • Jatoi, A.1    Rowland, K.2    Sloan, J.A.3
  • 43
    • 31344454556 scopus 로고    scopus 로고
    • An acneiform eruption due to erlotinib: Prognostic implications and management
    • Journagan S, Obadiah J. 2006. An acneiform eruption due to erlotinib: Prognostic implications and management. J Am Academy of Derm, 54:358-60.
    • (2006) J Am Academy of Derm , vol.54 , pp. 358-360
    • Journagan, S.1    Obadiah, J.2
  • 44
    • 37349037667 scopus 로고    scopus 로고
    • Updated analysis of SWOG 0023:A randomized phase III trial of gefitinib versus placebo maintenance after definitive chemoradiation followed by docetaxel in patients with locally advanced stage III non-small cell lung cancer
    • 18S:abst# 7513
    • Kelly K, Chansky K, Gaspar LE, et al. 2007. Updated analysis of SWOG 0023:A randomized phase III trial of gefitinib versus placebo maintenance after definitive chemoradiation followed by docetaxel in patients with locally advanced stage III non-small cell lung cancer. J Clin Oncol, Proc ASCO, 25, 18S:abst# 7513.
    • (2007) J Clin Oncol, Proc ASCO , vol.25
    • Kelly, K.1    Chansky, K.2    Gaspar, L.E.3
  • 45
    • 80052999776 scopus 로고    scopus 로고
    • Final results of ECOG 3503:A pilot study to determine if downstream markers of EGFR linked signaling pathways predict response to erlotinib (OSI-774) in the first-line treatment of patients with advanced non-small cell lung cancer (NSCLC)
    • 18S:abst# 7588
    • Kolesar J, Brahmer J, Lee J, et al. 2007. Final results of ECOG 3503:A pilot study to determine if downstream markers of EGFR linked signaling pathways predict response to erlotinib (OSI-774) in the first-line treatment of patients with advanced non-small cell lung cancer (NSCLC). J Clin Oncol, Proc ASCO, 25, 18S:abst# 7588.
    • (2007) J Clin Oncol, Proc ASCO , vol.25
    • Kolesar, J.1    Brahmer, J.2    Lee, J.3
  • 46
    • 0142055937 scopus 로고    scopus 로고
    • Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
    • Kris MG, Natale RB, Herbst RS, et al. 2003. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA, 290:2149-58.
    • (2003) JAMA , vol.290 , pp. 2149-2158
    • Kris, M.G.1    Natale, R.B.2    Herbst, R.S.3
  • 47
    • 72849145375 scopus 로고    scopus 로고
    • Association between different potential predictive markers from TRUST, a trial of erlotinib in non-small cell lung cancer
    • 18S:abst# 7651
    • Laack E, Schneider C, Gutjahr T, et al. 2007. Association between different potential predictive markers from TRUST, a trial of erlotinib in non-small cell lung cancer. J Clin Oncol, Proc ASCO, 25, 18S:abst# 7651.
    • (2007) J Clin Oncol, Proc ASCO , vol.25
    • Laack, E.1    Schneider, C.2    Gutjahr, T.3
  • 48
    • 0842264243 scopus 로고    scopus 로고
    • Cutaneous side effects in non-small cell lung cancer patients treated with Iressa (zd1839), an inhibitor of epidermal growth factor
    • Lee M, Seo C, Kim S, et al. 2004. Cutaneous side effects in non-small cell lung cancer patients treated with Iressa (zd1839), an inhibitor of epidermal growth factor. Acta Derm Veneroel, 84:23-6.
    • (2004) Acta Derm Veneroel , vol.84 , pp. 23-26
    • Lee, M.1    Seo, C.2    Kim, S.3
  • 49
    • 34250694236 scopus 로고    scopus 로고
    • Differential metabolism of gefitinib and erlotinib by human cytochrome P450 enzymes
    • Differential metabolism of gefitinib and erlotinib by human cytochrome P450 enzymes
    • Li J, Zhao M, He P, et al. 2007. Differential metabolism of gefitinib and erlotinib by human cytochrome P450 enzymes. Clin Cancer Res, 13:3731-7.
    • Clin Cancer Res , vol.13 , pp. 3731-3737
    • Li, J.1    Zhao, M.2    He, P.3
  • 50
    • 33846408842 scopus 로고    scopus 로고
    • Randomized phase II trial of single agent erlotinib vs. standard chemotherapy in patients with advanced non-small cell lung cancer (NSCLC) and performance status (PS) of 2
    • 18S:abst# 7022
    • Lilenbaum R, Axerold R, Thomas S, et al. 2006. Randomized phase II trial of single agent erlotinib vs. standard chemotherapy in patients with advanced non-small cell lung cancer (NSCLC) and performance status (PS) of 2. J Clin Oncol, Proc ASCO, 24, 18S:abst# 7022.
    • (2006) J Clin Oncol, Proc ASCO , vol.24
    • Lilenbaum, R.1    Axerold, R.2    Thomas, S.3
  • 51
    • 33846701647 scopus 로고    scopus 로고
    • Photosensitive rash due to the epidermal growth factor receptor inhibitor erlotinib
    • Luu M, Lai SE, Patel J, et al. 2007. Photosensitive rash due to the epidermal growth factor receptor inhibitor erlotinib. Photodermatol Photoimmunol Photomed, 23:42-5.
    • (2007) Photodermatol Photoimmunol Photomed , vol.23 , pp. 42-45
    • Luu, M.1    Lai, S.E.2    Patel, J.3
  • 52
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of nonsmall-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, et al. 2004. Activating mutations in the epidermal growth factor receptor underlying responsiveness of nonsmall-cell lung cancer to gefitinib. N Engl J Med, 350:2129-39.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 53
    • 35548962413 scopus 로고    scopus 로고
    • Randomised, double-blind multicentre phase III study of bevacizumab in combination with cisplatin and gemcitabine in chemotherapy-naïve patients with advanced or recurrent non-squamous non-small cell lung cancer (NSCLC):BO17704
    • The BO17704 study group. 18S:abst# LBA7514
    • Manegold C, von Pawel J, Zatloukal P, et al. 2007. The BO17704 study group. Randomised, double-blind multicentre phase III study of bevacizumab in combination with cisplatin and gemcitabine in chemotherapy-naïve patients with advanced or recurrent non-squamous non-small cell lung cancer (NSCLC):BO17704. J Clin Oncol, Proc ASCO, 25, 18S:abst# LBA7514.
    • (2007) J Clin Oncol, Proc ASCO , vol.25
    • Manegold, C.1    von Pawel, J.2    Zatloukal, P.3
  • 54
    • 33947389287 scopus 로고    scopus 로고
    • EGFR mutation and copy number, EGFR protein expression and KRAS mutation as predictors of outcome with erlotinib in bronchioloalveolar cell carcinoma (BAC): Results of a prospective phase II trial
    • 18S:abst# 7003
    • Miller VA, Zakowski M, Riely GJ, et al. 2006. EGFR mutation and copy number, EGFR protein expression and KRAS mutation as predictors of outcome with erlotinib in bronchioloalveolar cell carcinoma (BAC): Results of a prospective phase II trial. J of Clin Oncol, Proc ASCO, 24, 18S:abst# 7003.
    • (2006) J of Clin Oncol, Proc ASCO , vol.24
    • Miller, V.A.1    Zakowski, M.2    Riely, G.J.3
  • 55
    • 33747886041 scopus 로고    scopus 로고
    • A phase I/II study of weekly high dose erlotinib in previously treated patients with non-small cell cancer
    • Milton DT, Azzoli CG, Heelan RT, et al. 2006. A phase I/II study of weekly high dose erlotinib in previously treated patients with non-small cell cancer. Cancer, 107:1034-41.
    • (2006) Cancer , vol.107 , pp. 1034-1041
    • Milton, D.T.1    Azzoli, C.G.2    Heelan, R.T.3
  • 56
    • 34249933404 scopus 로고    scopus 로고
    • Erlotinib Plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer:A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
    • Moore MJ, Goldstein D, Hamm J, et al. 2007. Erlotinib Plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer:A phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol, 25:1960-66.
    • (2007) J Clin Oncol , vol.25 , pp. 1960-1966
    • Moore, M.J.1    Goldstein, D.2    Hamm, J.3
  • 57
    • 34250837538 scopus 로고    scopus 로고
    • Patterns of EGFR, HER2, TP53, and KRAS Mutations of p14arf Expression in nonsmall cell Lung Cancers in Relation to Smoking History
    • Mounawar M, Mukeria A, Calvez FL, et al. 2007. Patterns of EGFR, HER2, TP53, and KRAS Mutations of p14arf Expression in nonsmall cell Lung Cancers in Relation to Smoking History. Cancer Res, 67:5667-72.
    • (2007) Cancer Res , vol.67 , pp. 5667-5672
    • Mounawar, M.1    Mukeria, A.2    Calvez, F.L.3
  • 58
    • 33750087886 scopus 로고    scopus 로고
    • ZD6474 versus gefitinib in patients with advanced NSCLC:Final results from a two-part, double blind, randomized phase II trial
    • 18S:abst# 7000
    • Natale RB, Bodkin D, Govindan R, et al. 2006. ZD6474 versus gefitinib in patients with advanced NSCLC:Final results from a two-part, double blind, randomized phase II trial. J Clin Oncol, Proc ASCO, 24, 18S:abst# 7000.
    • (2006) J Clin Oncol, Proc ASCO , vol.24
    • Natale, R.B.1    Bodkin, D.2    Govindan, R.3
  • 59
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Janne PA, Lee JC, et al. 2004. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science, 304:1497-500.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3
  • 60
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M, et al. 2004. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA, 101:13306-11.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 61
    • 33845434121 scopus 로고    scopus 로고
    • A prospective phase II trial of erlotinib in advanced non-small cell lung cancer (NSCLC) patients (p) with mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR)
    • (18S)# 7020
    • Paz-Ares L, Sanchez JM, Garcia-Velasco A, et al. 2006. A prospective phase II trial of erlotinib in advanced non-small cell lung cancer (NSCLC) patients (p) with mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR). J Clin Oncol, ASCO proc, 24 (18S)# 7020.
    • (2006) J Clin Oncol, ASCO Proc , vol.24
    • Paz-Ares, L.1    Sanchez, J.M.2    Garcia-Velasco, A.3
  • 62
    • 4344646459 scopus 로고    scopus 로고
    • Determinants of tumor response and survival with erlotinib in patients with non-small cell lung cancer
    • Perez-Soler R, Chachoua A, Hammond LA, et al. 2004. Determinants of tumor response and survival with erlotinib in patients with non-small cell lung cancer. J Clin Oncol, 22:3238-47.
    • (2004) J Clin Oncol , vol.22 , pp. 3238-3247
    • Perez-Soler, R.1    Chachoua, A.2    Hammond, L.A.3
  • 63
    • 0001223491 scopus 로고    scopus 로고
    • Neutralizing antibodies against epidermal growth factor and ErbB2-neu receptor tyrosine kinase downregulate vascular endothelial growth factor production by tumor cells in vitro and in vivo
    • Petit AM, Rak J, Hung MC, et al. 1997. Neutralizing antibodies against epidermal growth factor and ErbB2-neu receptor tyrosine kinase downregulate vascular endothelial growth factor production by tumor cells in vitro and in vivo. Am J Pathol, 151:1523-30.
    • (1997) Am J Pathol , vol.151 , pp. 1523-1530
    • Petit, A.M.1    Rak, J.2    Hung, M.C.3
  • 64
    • 83455255947 scopus 로고    scopus 로고
    • A randomized phase II trial comparing pulsed erlotinib before or after carboplatin in patients with stage IIIB or IV non-small cell lung cancer
    • 18S:abst# 7619
    • Riely GJ, Rudin CM, Kris MG, et al. 2007. A randomized phase II trial comparing pulsed erlotinib before or after carboplatin in patients with stage IIIB or IV non-small cell lung cancer. J Clin Oncol, Proc ASCO, 25, 18S:abst# 7619.
    • (2007) J Clin Oncol, Proc ASCO , vol.25
    • Riely, G.J.1    Rudin, C.M.2    Kris, M.G.3
  • 65
    • 2142641698 scopus 로고    scopus 로고
    • Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
    • Saltz LB, Meropol NJ, Loehrer PJ, Sr., et al. 2004. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol, 22:1201-8.
    • (2004) J Clin Oncol , vol.22 , pp. 1201-1208
    • Saltz, L.B.1    Meropol, N.J.2    Loehrer, P.J.3
  • 66
    • 33845490014 scopus 로고    scopus 로고
    • PaclitaxelCarboplatin Alone or with Bevacizumab for non-small cell Lung Cancer
    • Sandler A, Gray R, Perry MC, et al. 2006a. PaclitaxelCarboplatin Alone or with Bevacizumab for non-small cell Lung Cancer. N Eng J Med, 355:2542-50.
    • (2006) N Eng J Med , vol.355 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.C.3
  • 67
    • 33746911955 scopus 로고    scopus 로고
    • Combining targeted agents:Blocking the epidermal growth factor and vascular endothelial growth factor
    • Sandler A, Herbst R. 2006b. Combining targeted agents:blocking the epidermal growth factor and vascular endothelial growth factor. Clin Cancer Res, 12:4421s-25s.
    • (2006) Clin Cancer Res , vol.12
    • Sandler, A.1    Herbst, R.2
  • 68
    • 0020933452 scopus 로고
    • Biological effect in vitro of monoclonal antibodies to human EGF receptors
    • Sato JD, Kawamoto T, Le AD, et al. 1983. Biological effect in vitro of monoclonal antibodies to human EGF receptors. Mol Biol Med, 1:511-2.
    • (1983) Mol Biol Med , vol.1 , pp. 511-512
    • Sato, J.D.1    Kawamoto, T.2    Le, A.D.3
  • 69
    • 0037050352 scopus 로고    scopus 로고
    • Comparison of four chemotherapy regimens for advanced non-small cell lung cancer
    • Schiller JH, Harrington D, Belani CP, et al. 2002. Comparison of four chemotherapy regimens for advanced non-small cell lung cancer. N Eng J Med, 346:92-8.
    • (2002) N Eng J Med , vol.346 , pp. 92-98
    • Schiller, J.H.1    Harrington, D.2    Belani, C.P.3
  • 70
    • 52149093304 scopus 로고    scopus 로고
    • Biomarker analysis from TRUST, a trial of erlotinib in non-small cell lung cancer (NSCLC)
    • 18S:abst# 7674
    • Schneider C, Schott-von Romer K, Gutz S, et al. 2007. Biomarker analysis from TRUST, a trial of erlotinib in non-small cell lung cancer (NSCLC). J Clin Oncol, Proc ASCO, 25, 18S:abst# 7674.
    • (2007) J Clin Oncol, Proc ASCO , vol.25
    • Schneider, C.1    Schott-Von R., K.2    Gutz, S.3
  • 71
    • 33846444010 scopus 로고    scopus 로고
    • Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing
    • Sequist LV, Joshi VA, Janne PA, et al. 2007. Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing. The Oncologist, 12:90-8.
    • (2007) The Oncologist , vol.12 , pp. 90-98
    • Sequist, L.V.1    Joshi, V.A.2    Janne, P.A.3
  • 72
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small cell lung cancer
    • Shepherd FA, J. Rodrigues Pereira, Ciuleanu T, et al. 2005. Erlotinib in previously treated non-small cell lung cancer. N Engl J Med, 353:123-32.
    • (2005) N Engl J Med , vol.353 , pp. 123-132
    • Shepherd, F.A.1    Rodrigues P., J.2    Ciuleanu, T.3
  • 73
    • 0034069620 scopus 로고    scopus 로고
    • Prospective randomized trial of docetaxel versus best supportive care in patients with non-small cell lung cancer previously treated with platinum-based chemotherapy
    • Shepherd F, Dancey J, Ramlau R, et al. 2000. Prospective randomized trial of docetaxel versus best supportive care in patients with non-small cell lung cancer previously treated with platinum-based chemotherapy. J Clin Oncol, 18:2095-103.
    • (2000) J Clin Oncol , vol.18 , pp. 2095-2103
    • Shepherd, F.1    Dancey, J.2    Ramlau, R.3
  • 74
    • 34347393745 scopus 로고    scopus 로고
    • Mass spectrometry to classify non-small cell lung cancer patients for clinical outcome after treatment with epidermal growth factor receptor tyrosine kinase inhibitors:A multicohort cross-institutional study
    • Taguchi F, Solomon B, Gregorc V, et al. 2007. Mass spectrometry to classify non-small cell lung cancer patients for clinical outcome after treatment with epidermal growth factor receptor tyrosine kinase inhibitors:A multicohort cross-institutional study. J Natl Cancer Inst, 99:838-46.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 838-846
    • Taguchi, F.1    Solomon, B.2    Gregorc, V.3
  • 75
    • 33645052711 scopus 로고    scopus 로고
    • Distinct Epidermal Growth Factor Receptor and KRAS Mutation Patterns in non-small cell Lung Cancer Patients with Different Tobacco Exposure and Clinicopathologic Features
    • Tam IYS, Chung LP, Suen WS, et al. 2006. Distinct Epidermal Growth Factor Receptor and KRAS Mutation Patterns in non-small cell Lung Cancer Patients with Different Tobacco Exposure and Clinicopathologic Features. Clin Cancer Res, 12:1647-53.
    • (2006) Clin Cancer Res , vol.12 , pp. 1647-1653
    • Tam, I.Y.S.1    Chung, L.P.2    Suen, W.S.3
  • 76
    • 27544503230 scopus 로고    scopus 로고
    • Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small cell lung cancer:Results from a randomized, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
    • Thatcher N, Chang A, Parikh P, et al. 2005. Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small cell lung cancer:results from a randomized, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer). Lancet, 366:1527-37.
    • (2005) Lancet , vol.366 , pp. 1527-1537
    • Thatcher, N.1    Chang, A.2    Parikh, P.3
  • 77
    • 22044453790 scopus 로고    scopus 로고
    • Erlotinib in lung cancermolecular and clinical predictors of outcome
    • Tsao MS, Sakurada A, Cutz JC, et al. 2005. Erlotinib in lung cancermolecular and clinical predictors of outcome. N Engl J Med, 353:133-44.
    • (2005) N Engl J Med , vol.353 , pp. 133-144
    • Tsao, M.S.1    Sakurada, A.2    Cutz, J.C.3
  • 78
    • 34250329445 scopus 로고    scopus 로고
    • EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity
    • Vikis H, Sato M, James M, et al. 2007. EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity. Cancer Res, 67:4665-70.
    • (2007) Cancer Res , vol.67 , pp. 4665-4670
    • Vikis, H.1    Sato, M.2    James, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.