-
1
-
-
76449098262
-
PHENIX: A comprehensive Python-based system for macromolecular structure solution
-
P.D. Adams, P.V. Afonine, G. Bunkóczi, V.B. Chen, I.W. Davis, N. Echols, J.J. Headd, L.W. Hung, G.J. Kapral, and R.W. Grosse-Kunstleve PHENIX: a comprehensive Python-based system for macromolecular structure solution Acta Crystallogr. D Biol. Crystallogr. 66 2010 213 221
-
(2010)
Acta Crystallogr. D Biol. Crystallogr.
, vol.66
, pp. 213-221
-
-
Adams, P.D.1
Afonine, P.V.2
Bunkóczi, G.3
Chen, V.B.4
Davis, I.W.5
Echols, N.6
Headd, J.J.7
Hung, L.W.8
Kapral, G.J.9
Grosse-Kunstleve, R.W.10
-
2
-
-
82155181559
-
Characterization and functional modification of StaC and RebC, which are involved in the pyrrole oxidation of indolocarbazole biosynthesis
-
S. Asamizu, Y. Shiro, Y. Igarashi, S. Nagano, and H. Onaka Characterization and functional modification of StaC and RebC, which are involved in the pyrrole oxidation of indolocarbazole biosynthesis Biosci. Biotechnol. Biochem. 75 2011 2184 2193
-
(2011)
Biosci. Biotechnol. Biochem.
, vol.75
, pp. 2184-2193
-
-
Asamizu, S.1
Shiro, Y.2
Igarashi, Y.3
Nagano, S.4
Onaka, H.5
-
3
-
-
0036008509
-
Reliable quality-control methods for protein crystal structures
-
J. Badger, and J. Hendle Reliable quality-control methods for protein crystal structures Acta Crystallogr. D Biol. Crystallogr. 58 2002 284 291
-
(2002)
Acta Crystallogr. D Biol. Crystallogr.
, vol.58
, pp. 284-291
-
-
Badger, J.1
Hendle, J.2
-
4
-
-
0030944043
-
DNA cleavage by topoisomerase i in the presence of indolocarbazole derivatives of rebeccamycin
-
C. Bailly, J.F. Riou, P. Colson, C. Houssier, E. Rodrigues-Pereira, and M. Prudhomme DNA cleavage by topoisomerase I in the presence of indolocarbazole derivatives of rebeccamycin Biochemistry 36 1997 3917 3929
-
(1997)
Biochemistry
, vol.36
, pp. 3917-3929
-
-
Bailly, C.1
Riou, J.F.2
Colson, P.3
Houssier, C.4
Rodrigues-Pereira, E.5
Prudhomme, M.6
-
5
-
-
35649004965
-
Crystallography gets the jump on the enzymologists
-
D.P. Ballou Crystallography gets the jump on the enzymologists Proc. Natl. Acad. Sci. USA 104 2007 15587 15588
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 15587-15588
-
-
Ballou, D.P.1
-
6
-
-
37049014272
-
Version 1.2 of the Crystallography and NMR system
-
A.T. Brünger Version 1.2 of the Crystallography and NMR system Nat. Protoc. 2 2007 2728 2733
-
(2007)
Nat. Protoc.
, vol.2
, pp. 2728-2733
-
-
Brünger, A.T.1
-
7
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination
-
A.T. Brünger, P.D. Adams, G.M. Clore, W.L. DeLano, P. Gros, R.W. Grosse-Kunstleve, J.S. Jiang, J. Kuszewski, M. Nilges, and N.S. Pannu Crystallography & NMR system: a new software suite for macromolecular structure determination Acta Crystallogr. D Biol. Crystallogr. 54 1998 905 921
-
(1998)
Acta Crystallogr. D Biol. Crystallogr.
, vol.54
, pp. 905-921
-
-
Brünger, A.T.1
Adams, P.D.2
Clore, G.M.3
Delano, W.L.4
Gros, P.5
Grosse-Kunstleve, R.W.6
Jiang, J.S.7
Kuszewski, J.8
Nilges, M.9
Pannu, N.S.10
-
8
-
-
70349630235
-
Phase II and pharmacokinetic trial of rebeccamycin analog in advanced biliary cancers
-
A. Dowlati, J. Posey, R.K. Ramanathan, L. Rath, P. Fu, A. Chak, S. Krishnamurthi, J. Brell, S. Ingalls, and C.L. Hoppel Phase II and pharmacokinetic trial of rebeccamycin analog in advanced biliary cancers Cancer Chemother. Pharmacol. 65 2009 73 78
-
(2009)
Cancer Chemother. Pharmacol.
, vol.65
, pp. 73-78
-
-
Dowlati, A.1
Posey, J.2
Ramanathan, R.K.3
Rath, L.4
Fu, P.5
Chak, A.6
Krishnamurthi, S.7
Brell, J.8
Ingalls, S.9
Hoppel, C.L.10
-
9
-
-
34249104303
-
Phase i and pharmacokinetic study of 7-hydroxystaurosporine and carboplatin in advanced solid tumors
-
M.J. Edelman, K.S. Bauer Jr., S. Wu, R. Smith, S. Bisacia, and J. Dancey Phase I and pharmacokinetic study of 7-hydroxystaurosporine and carboplatin in advanced solid tumors Clin. Cancer Res. 13 2007 2667 2674
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 2667-2674
-
-
Edelman, M.J.1
Bauer Jr., K.S.2
Wu, S.3
Smith, R.4
Bisacia, S.5
Dancey, J.6
-
11
-
-
0032524753
-
The crystal structure of phenol hydroxylase in complex with FAD and phenol provides evidence for a concerted conformational change in the enzyme and its cofactor during catalysis
-
C. Enroth, H. Neujahr, G. Schneider, and Y. Lindqvist The crystal structure of phenol hydroxylase in complex with FAD and phenol provides evidence for a concerted conformational change in the enzyme and its cofactor during catalysis Structure 6 1998 605 617
-
(1998)
Structure
, vol.6
, pp. 605-617
-
-
Enroth, C.1
Neujahr, H.2
Schneider, G.3
Lindqvist, Y.4
-
12
-
-
0030716522
-
Identification of a novel conserved sequence motif in flavoprotein hydroxylases with a putative dual function in FAD/NAD(P)H binding
-
M.H. Eppink, H.A. Schreuder, and W.J. Van Berkel Identification of a novel conserved sequence motif in flavoprotein hydroxylases with a putative dual function in FAD/NAD(P)H binding Protein Sci. 6 1997 2454 2458
-
(1997)
Protein Sci.
, vol.6
, pp. 2454-2458
-
-
Eppink, M.H.1
Schreuder, H.A.2
Van Berkel, W.J.3
-
13
-
-
33746218306
-
Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: Insights from the AT2433 biosynthetic locus
-
Q. Gao, C. Zhang, S. Blanchard, and J.S. Thorson Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus Chem. Biol. 13 2006 733 743
-
(2006)
Chem. Biol.
, vol.13
, pp. 733-743
-
-
Gao, Q.1
Zhang, C.2
Blanchard, S.3
Thorson, J.S.4
-
14
-
-
27144505097
-
Protein identification and analysis tools on the ExPASy server
-
J.M. Walker, Humana Press New York, NY
-
E. Gasteiger, C. Hoogland, A. Gattiker, S. Duvaud, M.R. Wilkins, R.D. Appel, and A. Bairoch Protein Identification and Analysis Tools on the ExPASy Server J.M. Walker, The Proteomics Protocols Handbook 2005 Humana Press New York, NY 571 607
-
(2005)
The Proteomics Protocols Handbook
, pp. 571-607
-
-
Gasteiger, E.1
Hoogland, C.2
Gattiker, A.3
Duvaud, S.4
Wilkins, M.R.5
Appel, R.D.6
Bairoch, A.7
-
15
-
-
0027999378
-
The mobile flavin of 4-OH benzoate hydroxylase
-
D.L. Gatti, B.A. Palfey, M.S. Lah, B. Entsch, V. Massey, D.P. Ballou, and M.L. Ludwig The mobile flavin of 4-OH benzoate hydroxylase Science 266 1994 110 114
-
(1994)
Science
, vol.266
, pp. 110-114
-
-
Gatti, D.L.1
Palfey, B.A.2
Lah, M.S.3
Entsch, B.4
Massey, V.5
Ballou, D.P.6
Ludwig, M.L.7
-
16
-
-
79551520264
-
Rebeccamycin and staurosporine biosynthesis: Insight into the mechanisms of the flavin-dependent monooxygenases RebC and StaC
-
K. Groom, A. Bhattacharya, and D.L. Zechel Rebeccamycin and staurosporine biosynthesis: insight into the mechanisms of the flavin-dependent monooxygenases RebC and StaC ChemBioChem 12 2011 396 400
-
(2011)
ChemBioChem
, vol.12
, pp. 396-400
-
-
Groom, K.1
Bhattacharya, A.2
Zechel, D.L.3
-
17
-
-
0037454672
-
A His-tag based immobilization method for the preparation and reconstitution of apoflavoproteins
-
M.H. Hefti, F.J. Milder, S. Boeren, J. Vervoort, and W.J. van Berkel A His-tag based immobilization method for the preparation and reconstitution of apoflavoproteins Biochim. Biophys. Acta 1619 2003 139 143
-
(2003)
Biochim. Biophys. Acta
, vol.1619
, pp. 139-143
-
-
Hefti, M.H.1
Milder, F.J.2
Boeren, S.3
Vervoort, J.4
Van Berkel, W.J.5
-
18
-
-
33748758449
-
Staurosporine and rebeccamycin aglycones are assembled by the oxidative action of StaP, StaC, and RebC on chromopyrrolic acid
-
A.R. Howard-Jones, and C.T. Walsh Staurosporine and rebeccamycin aglycones are assembled by the oxidative action of StaP, StaC, and RebC on chromopyrrolic acid J. Am. Chem. Soc. 128 2006 12289 12298
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 12289-12298
-
-
Howard-Jones, A.R.1
Walsh, C.T.2
-
19
-
-
33847186292
-
Species-specific secondary metabolite production in marine actinomycetes of the genus Salinispora
-
P.R. Jensen, P.G. Williams, D.C. Oh, L. Zeigler, and W. Fenical Species-specific secondary metabolite production in marine actinomycetes of the genus Salinispora Appl. Environ. Microbiol. 73 2007 1146 1152
-
(2007)
Appl. Environ. Microbiol.
, vol.73
, pp. 1146-1152
-
-
Jensen, P.R.1
Williams, P.G.2
Oh, D.C.3
Zeigler, L.4
Fenical, W.5
-
20
-
-
37249042758
-
Phase i and pharmacokinetic study of UCN-01 in combination with irinotecan in patients with solid tumors
-
A. Jimeno, M.A. Rudek, T. Purcell, D.A. Laheru, W.A. Messersmith, J. Dancey, M.A. Carducci, S.D. Baker, M. Hidalgo, and R.C. Donehower Phase I and pharmacokinetic study of UCN-01 in combination with irinotecan in patients with solid tumors Cancer Chemother. Pharmacol. 61 2008 423 433
-
(2008)
Cancer Chemother. Pharmacol.
, vol.61
, pp. 423-433
-
-
Jimeno, A.1
Rudek, M.A.2
Purcell, T.3
Laheru, D.A.4
Messersmith, W.A.5
Dancey, J.6
Carducci, M.A.7
Baker, S.D.8
Hidalgo, M.9
Donehower, R.C.10
-
21
-
-
34250675327
-
Genetic organization of the biosynthetic gene cluster for the indolocarbazole K-252a in Nonomuraea longicatena JCM 11136
-
S.Y. Kim, J.S. Park, C.S. Chae, C.G. Hyun, B.W. Choi, J. Shin, and K.B. Oh Genetic organization of the biosynthetic gene cluster for the indolocarbazole K-252a in Nonomuraea longicatena JCM 11136 Appl. Microbiol. Biotechnol. 75 2007 1119 1126
-
(2007)
Appl. Microbiol. Biotechnol.
, vol.75
, pp. 1119-1126
-
-
Kim, S.Y.1
Park, J.S.2
Chae, C.S.3
Hyun, C.G.4
Choi, B.W.5
Shin, J.6
Oh, K.B.7
-
22
-
-
0002435359
-
Simple method for the determination of redox potentials
-
B. Curti, S. Ronchi, G. Zanetti, Walter de Gruyter Berlin, Germany
-
V.A. Massey Simple method for the determination of redox potentials B. Curti, S. Ronchi, G. Zanetti, Flavins and Flavoproteins 1991 Walter de Gruyter Berlin, Germany 59 66
-
(1991)
Flavins and Flavoproteins
, pp. 59-66
-
-
Massey, V.A.1
-
23
-
-
80052794668
-
Catalytic and structural features of flavoprotein hydroxylases and epoxidases
-
10.1002/adsc.201100384
-
S. Montersino, D. Tischler, G.T. Gassner, and W.J.H. van Berkel Catalytic and structural features of flavoprotein hydroxylases and epoxidases Adv. Synth. Catal. 353 2011 2301 2319 10.1002/adsc.201100384
-
(2011)
Adv. Synth. Catal.
, vol.353
, pp. 2301-2319
-
-
Montersino, S.1
Tischler, D.2
Gassner, G.T.3
Van Berkel, W.J.H.4
-
24
-
-
79151484294
-
A phase i study of rebeccamycin analog in combination with oxaliplatin in patients with refractory solid tumors
-
C.J. Nock, J.M. Brell, J.A. Bokar, M.M. Cooney, B. Cooper, J. Gibbons, S. Krishnamurthi, S. Manda, P. Savvides, and S.C. Remick A phase I study of rebeccamycin analog in combination with oxaliplatin in patients with refractory solid tumors Invest. New Drugs 29 2011 126 130
-
(2011)
Invest. New Drugs
, vol.29
, pp. 126-130
-
-
Nock, C.J.1
Brell, J.M.2
Bokar, J.A.3
Cooney, M.M.4
Cooper, B.5
Gibbons, J.6
Krishnamurthi, S.7
Manda, S.8
Savvides, P.9
Remick, S.C.10
-
25
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
10.1016/S0076-6879(97)76066-X
-
Z. Otwinowski, and W. Minor Processing of X-ray diffraction data collected in oscillation mode Methods Enzymol. 276 1997 307 326 10.1016/S0076-6879(97)76066-X
-
(1997)
Methods Enzymol.
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
26
-
-
0028328334
-
Changes in the catalytic properties of p-hydroxybenzoate hydroxylase caused by the mutation Asn300Asp
-
B.A. Palfey, B. Entsch, D.P. Ballou, and V. Massey Changes in the catalytic properties of p-hydroxybenzoate hydroxylase caused by the mutation Asn300Asp Biochemistry 33 1994 1545 1554
-
(1994)
Biochemistry
, vol.33
, pp. 1545-1554
-
-
Palfey, B.A.1
Entsch, B.2
Ballou, D.P.3
Massey, V.4
-
27
-
-
0024394417
-
Staurosporine, K-252 and UCN-01: Potent but nonspecific inhibitors of protein kinases
-
U.T. Rüegg, and G.M. Burgess Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases Trends Pharmacol. Sci. 10 1989 218 220
-
(1989)
Trends Pharmacol. Sci.
, vol.10
, pp. 218-220
-
-
Rüegg, U.T.1
Burgess, G.M.2
-
28
-
-
64749111045
-
Divergent pathways in the biosynthesis of bisindole natural products
-
K.S. Ryan, and C.L. Drennan Divergent pathways in the biosynthesis of bisindole natural products Chem. Biol. 16 2009 351 364
-
(2009)
Chem. Biol.
, vol.16
, pp. 351-364
-
-
Ryan, K.S.1
Drennan, C.L.2
-
29
-
-
34848910775
-
Crystallographic trapping in the rebeccamycin biosynthetic enzyme RebC
-
K.S. Ryan, A.R. Howard-Jones, M.J. Hamill, S.J. Elliott, C.T. Walsh, and C.L. Drennan Crystallographic trapping in the rebeccamycin biosynthetic enzyme RebC Proc. Natl. Acad. Sci. USA 104 2007 15311 15316
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 15311-15316
-
-
Ryan, K.S.1
Howard-Jones, A.R.2
Hamill, M.J.3
Elliott, S.J.4
Walsh, C.T.5
Drennan, C.L.6
-
30
-
-
58149144734
-
The FAD cofactor of RebC shifts to an in conformation upon flavin reduction
-
K.S. Ryan, S. Chakraborty, A.R. Howard-Jones, C.T. Walsh, D.P. Ballou, and C.L. Drennan The FAD cofactor of RebC shifts to an IN conformation upon flavin reduction Biochemistry 47 2008 13506 13513
-
(2008)
Biochemistry
, vol.47
, pp. 13506-13513
-
-
Ryan, K.S.1
Chakraborty, S.2
Howard-Jones, A.R.3
Walsh, C.T.4
Ballou, D.P.5
Drennan, C.L.6
-
31
-
-
12244279574
-
Combinatorial biosynthesis of antitumor indolocarbazole compounds
-
C. Sánchez, L. Zhu, A.F. Braña, A.P. Salas, J. Rohr, C. Méndez, and J.A. Salas Combinatorial biosynthesis of antitumor indolocarbazole compounds Proc. Natl. Acad. Sci. USA 102 2005 461 466
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 461-466
-
-
Sánchez, C.1
Zhu, L.2
Braña, A.F.3
Salas, A.P.4
Rohr, J.5
Méndez, C.6
Salas, J.A.7
-
32
-
-
33751335837
-
Indolocarbazole natural products: Occurrence, biosynthesis, and biological activity
-
C. Sánchez, C. Méndez, and J.A. Salas Indolocarbazole natural products: occurrence, biosynthesis, and biological activity Nat. Prod. Rep. 23 2006 1007 1045
-
(2006)
Nat. Prod. Rep.
, vol.23
, pp. 1007-1045
-
-
Sánchez, C.1
Méndez, C.2
Salas, J.A.3
-
33
-
-
34547094373
-
UCN-01 in combination with topotecan in patients with advanced recurrent ovarian cancer: A study of the Princess Margaret Hospital Phase II consortium
-
S. Welch, H.W. Hirte, M.S. Carey, S.J. Hotte, M.S. Tsao, S. Brown, G.R. Pond, J.E. Dancey, and A.M. Oza UCN-01 in combination with topotecan in patients with advanced recurrent ovarian cancer: a study of the Princess Margaret Hospital Phase II consortium Gynecol. Oncol. 106 2007 305 310
-
(2007)
Gynecol. Oncol.
, vol.106
, pp. 305-310
-
-
Welch, S.1
Hirte, H.W.2
Carey, M.S.3
Hotte, S.J.4
Tsao, M.S.5
Brown, S.6
Pond, G.R.7
Dancey, J.E.8
Oza, A.M.9
|