Characterization and functional modification of StaC and RebC, which are involved in the pyrrole oxidation of indolocarbazole biosynthesis

Bioscience, Biotechnology and Biochemistry

Volumn 75, Issue 11, 2011, Pages 2184-2193

  Asamizu, Shumpei ^a   Shiro, Yoshitsugu ^b   Igarashi, Yasuhiro ^a   Nagano, Shingo ^b,c   Onaka, Hiroyasu ^a  

^a TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^b RIKEN SPring 8 Center ^*  (Japan)

^c TOTTORI UNIVERSITY   (Japan)

Author keywords

FAD dependent monooxygenase; Indolocarbazole biosynthesis; Mutational analysis; Secondary metabolism; Streptomyces

Indexed keywords

INDOLOCARBAZOLES; MONOOXYGENASES; MUTATIONAL ANALYSIS; SECONDARY METABOLISM; STREPTOMYCES;

AMINO ACIDS; BINDING SITES; CATALYST ACTIVITY; METABOLISM;

BIOSYNTHESIS;

ARCYRIAFLAVIN A; CARBAZOLE DERIVATIVE; DIMETHYLANILINE MONOOXYGENASE; DIMETHYLANILINE MONOOXYGENASE (N-OXIDE FORMING); FLAVINE ADENINE NUCLEOTIDE; INDOLE ALKALOID; INDOLE DERIVATIVE; OXYGENASE; PYRROLE DERIVATIVE; REBECCAMYCIN; STAUROSPORINE; STAUROSPORINE AGLYCONE;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; OXIDATION REDUCTION REACTION; STREPTOMYCES; SYNTHESIS;

AMINO ACID SEQUENCE; BINDING SITES; CARBAZOLES; CLONING, MOLECULAR; FLAVIN-ADENINE DINUCLEOTIDE; INDOLE ALKALOIDS; INDOLES; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; OXYGENASES; PYRROLES; STAUROSPORINE; STREPTOMYCES; SUBSTRATE SPECIFICITY;

EID: 82155181559     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.110474     Document Type: Article

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