Rationalization of paclitaxel insensitivity of yeast β-tubulin and human βiII-tubulin isotype using principal component analysis

BMC Research Notes

Volumn 5, Issue , 2012, Pages

  Das, Lalita ^a   Bhattacharya, Bhabatarak ^a   Basu, Gautam ^a  

^a BOSE INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTA;

ALANINE; ANTINEOPLASTIC AGENT; FUNGAL PROTEIN; ISOPROTEIN; PACLITAXEL; TUBULIN; TUMOR PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG RESISTANCE; GENETICS; HUMAN; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; MUTATION; PLANT; PRINCIPAL COMPONENT ANALYSIS; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

ALANINE; AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; BINDING SITES; DRUG RESISTANCE, NEOPLASM; FUNGAL PROTEINS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASM PROTEINS; PACLITAXEL; PLANTS; PRINCIPAL COMPONENT ANALYSIS; PROTEIN BINDING; PROTEIN ISOFORMS; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID; TUBULIN;

EID: 84864404563     PISSN: None     EISSN: 17560500     Source Type: Journal    
DOI: 10.1186/1756-0500-5-395     Document Type: Article

References (36)

1. Microtubule dynamics. Avila J, FASEB J 1990 4 3284 3290 2253844 (Pubitemid 120012575)
2. Programmed expression of beta-tubulin genes during development and differentiation of the chicken. Havercroft JC, Cleveland DW, J Cell Biol 1984 99 1927 1935 10.1083/jcb.99.6.1927 6094589 (Pubitemid 15181853)
3. Selective synthesis and utilization of flagellar tubulin. The multi-tubulin hypothesis. Fulton C, Simpson PA, Cell Motility Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, Goldman R, Pollard T, Rosenbaum J, 1976 987 1006
4. Distinct colchicine binding kinetics of bovine brain tubulin lacking the type III isotype of beta-tubulin. Banerjee A, Luduena RF, J Biol Chem 1991 266 1689 1691 1988443 (Pubitemid 21908356)
5. Kinetics of colchicine binding to purified beta-tubulin isotypes from bovine brain. Banerjee A, Luduena RF, J Biol Chem 1992 267 13335 13339 1618835
6. Taxol stabilizes microtubules in mouse fibroblast cells. Schiff PB, Horwitz SB, Proc Natl Acad Sci USA 1980 77 1561 1565 10.1073/pnas.77.3.1561 6103535 (Pubitemid 10073801)
7. Mechanism of action of taxol. Horwitz SB, Trends Pharmacol Sci 1992 13 134 136 1350385
8. Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Jordan M, Toso RJ, Thrower D, Wilson L, Proc Natl Acad Sci USA 1993 90 9552 9556 10.1073/pnas.90.20.9552 8105478 (Pubitemid 23315823)
9. Taxol: a unique antineoplastic agent with significant activity in advanced ovarian epithelial neoplasms. McGuire WP, Rowinsky EK, Rosenshein NB, Grumbine FC, Ettinger DS, Armstrong DK, Donehower RC, Ann Intern Med 1989 111 273 279 2569287 (Pubitemid 19204753)
10. Phase II trial of taxol, an active drug in the treatment of metastatic breast cancer. Holmes FA, Walters RS, Theriault RL, Forman AD, Newton LK, Raber MN, Buzdar AU, Frye DK, Hortobagyi GN, J Natl Cancer Inst 1991 83 1797 1805 1683908
11. Antisense oligonucleotides to class III beta-tubulin sensitize drug-resistant cells to Taxol. Kavallaris M, Burkhart CA, Horwitz SB, Br J Cancer 1999 80 1020 1025 10.1038/sj.bjc.6690507 10362110 (Pubitemid 29233923)
12. Expression of class III beta-tubulin reduces microtubule assembly and confers resistance to paclitaxel. Hari M, Yang H, Zeng C, Canizales M, Cabral F, Cell Motil Cytoskeleton 2003 56 45 56 10.1002/cm.10132 12905530 (Pubitemid 37059485)
13. BetaIII-tubulin induces paclitaxel resistance in association with reduced effects on microtubule dynamic instability. Kamath K, Wilson L, Cabral F, Jordan MA, J Biol Chem 2005 280 12902 12907 15695826
14. Microtubule dynamics in vitro are regulated by the tubulin isotype composition. Panda D, Miller HP, Banerjee A, Luduẽa RF, Wilson L, Proc Natl Acad Sci USA 1994 91 11358 11362 10.1073/pnas.91.24.11358 7972064 (Pubitemid 24356343)
15. Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry. Verdier-Pinard P, Wang F, Martello L, Burd B, Orr GA, Horwitz SB, Biochemistry 2003 42 5349 5357 10.1021/bi027293o 12731876 (Pubitemid 36560431)
16. Expression of class III beta tubulin in non-small cell lung cancer is correlated with resistance to taxane chemotherapy. Dumontet C, Isaac S, Souquet PJ, Bejui-Thivolet F, Pacheco Y, Peloux N, Frankfurter A, Luduena R, Perol M, Bull Cancer 2005 92 25 E30 15749640
17. Class III beta-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients. Mozzetti S, Ferlini C, Concolino P, Filippetti F, Raspaglio G, Prislei S, Gallo D, Martinelli E, Ranelletti FO, Ferrandina G, Scambia G, Clin Cancer Res 2005 11 298 305 15671559 (Pubitemid 40075808)
18. Yeast proteins associated with microtubules in vitro and in vivo. Barnes G, Louie KA, Botstein D, Mol Biol Cell 1992 3 29 47 1348005 (Pubitemid 23094250)
19. Epothilone and paclitaxel: unexpected differences in promoting the assembly and stabilization of yeast microtubules. Bode CJ, Gupta ML, Reiff EA, Suprenant KA, Georg GI, Himes RH, Biochemistry 2002 41 3870 3874 10.1021/bi0121611 11900528 (Pubitemid 34251025)
20. Understanding tubulin-Taxol interactions: mutations that impart Taxol binding to yeast tubulin. Gupta ML, Bode CJ, Georg GI, Himes RH, Proc Natl Acad Sci USA 2003 100 6394 6397 10.1073/pnas.1131967100 12740436 (Pubitemid 36666592)
21. The paclitaxel site in tubulin probed by site-directed mutagenesis of Saccharomyces cerevisiae beta-tubulin. Entwistle RA, Winefield RD, Foland TB, Lushington GH, Himes RH, FEBS Lett 2008 582 2467 2470 10.1016/j.febslet.2008.06. 013 18570892
22. Structure of the alpha beta tubulin dimer by electron crystallography. Nogales E, Wolf SG, Downing KH, Nature 1998 391 199 203 10.1038/34465 9428769 (Pubitemid 28092482)
23. Refined structure of alpha beta-tubulin at 3.5 resolution. Lowe J, Li H, Downing KH, Nogales E, J Mol Biol 2001 313 1045 1057 10.1006/jmbi.2001.5077 11700061 (Pubitemid 33081900)
24. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Thompson JD, Higgins DG, Gibson TJ, Nucl Acids Res 1994 22 4673 4680 10.1093/nar/22.22.4673 7984417 (Pubitemid 24354800)
25. WebLogo: a sequence logo generator. Crooks GE, Hon G, Chandonia JM, Brenner SE, Gen Res 2004 14 1188 1190 10.1101/gr.849004 (Pubitemid 38811555)
26. Taxol stabilizes microtubules in mouse fibroblast cells. Parness J, Horwitz SB, J Cell Biol 1981 91 479 487 10.1083/jcb.91.2.479 6118377
27. Taxol-induced rose microtubule polymerization in vitro and its inhibition by colchicine. Morejohn LC, Fosket DE, J Cell Biol 1984 99 141 147 10.1083/jcb.99.1.141 6145718 (Pubitemid 14096877)
28. Unique functional characteristics of the polymerization and MAP binding regulatory domains of plant tubulin. Hugdahl JD, Bokros CL, Hanesworth VR, Aalund GR, Morejohn LC, Plant Cell 1993 5 1063 1080 8104575
29. A 90-kD phospholipase D from tobacco binds to microtubules and the plasma membrane. Gardiner JC, Harper JD, Weerakoon ND, Collings DA, Ritchie S, Gilroy S, Cyr RJ, Marc J, Plant Cell 2001 13 2143 2158 11549769 (Pubitemid 32919023)
30. Purification, characterization, and drug susceptibility of tubulin from Leishmania. Werbovetz KA, Brendle JJ, Sackett DL, Mol Biochem Parasitol 1999 98 53 65 10.1016/S0166-6851(98)00146-7 10029309 (Pubitemid 29027929)
31. Differential colchicine-binding across eukaryotic families: the role of highly conserved Pro268beta and Ala248beta residues in animal tubulin. Banerjee M, Roy D, Bhattacharyya B, Basu G, FEBS Lett 2007 581 5019 5023 10.1016/j.febslet.2007.09.047 17927988 (Pubitemid 47576085)
32. The betaI/betaIII-tubulin isoforms and their complexes with antimitotic agents. Docking and molecular dynamics studies. Magnani M, Ortuso F, Soro S, Alcaro S, Tramontano A, Botta M, FEBS J 2006 273 3301 3310 10.1111/j.1742-4658. 2006.05340.x 16803461 (Pubitemid 43990933)
33. A method to predict functional residues in proteins. Casari G, Sander C, Valencia A, Nat Struct Biol 1995 2 171 178 10.1038/nsb0295-171 7749921 (Pubitemid 26040653)
34. Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain. Ravelli RB, Gigant B, Curmi PA, Jourdain I, Lachkar S, Sobel A, Knossow M, Nature 2004 428 198 202 10.1038/nature02393 15014504 (Pubitemid 38374318)
35. The protein data bank. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE, Nucleic Acids Res 2000 28 235 241 10.1093/nar/28.1.235 10592235
36. UCSF Chimera-a visualization system for exploratory research and analysis. Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, Ferrin TE, J Comput Chem 2004 25 1605 1612 10.1002/jcc.20084 15264254