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Volumn 23, Issue 8, 2012, Pages 874-882

Indications for an alternative effective treatment of head and neck squamous cell carcinoma with temsirolimus plus bevacizumab: From bench to bedside?

Author keywords

bevacizumab; clinical cases; head and neck squamous cell carcinoma; in vitro; in vivo; temsirolimus

Indexed keywords

BEVACIZUMAB; CARBOPLATIN; CETUXIMAB; CISPLATIN; DOCETAXEL; FLUOROURACIL; IFOSFAMIDE; PACLITAXEL; TEMSIROLIMUS;

EID: 84864402806     PISSN: 09594973     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/CAD.0b013e3283538c3d     Document Type: Article
Times cited : (4)

References (33)
  • 2
    • 33748155274 scopus 로고    scopus 로고
    • Clinical implications of human papillomavirus in head and neck cancers
    • DOI 10.1200/JCO.2006.06.1291
    • Fakhry C, Gillison ML. Clinical implications of human papillomavirus in head and neck cancers. J Clin Oncol 2006; 24:2606-2611. (Pubitemid 46622080)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.17 , pp. 2606-2611
    • Fakhry, C.1    Gillison, M.L.2
  • 3
    • 2442540470 scopus 로고    scopus 로고
    • Focus on nasopharyngeal cancer
    • Lo KW, To KF, Huang DP. Focus on nasopharyngeal cancer. Cancer Cell 2004; 5:423-428.
    • (2004) Cancer Cell , vol.5 , pp. 423-428
    • Lo, K.W.1    To, K.F.2    Huang, D.P.3
  • 5
    • 51649093834 scopus 로고    scopus 로고
    • Recent advances in head and neck cancer
    • Haddad R, Shin D. Recent advances in head and neck cancer. N Engl J Med 2008; 359:1143-1154.
    • (2008) N Engl J Med , vol.359 , pp. 1143-1154
    • Haddad, R.1    Shin, D.2
  • 6
    • 0024999648 scopus 로고
    • Patterns of cervical lymph node metastasis from squamous carcinomas of the upper aerodigestive tract
    • Shah JP. Patterns of cervical lymph node metastasis from squamous carcinomas of the upper aerodigestive tract. Am J Surg 1990; 160: 405-409. (Pubitemid 20346332)
    • (1990) American Journal of Surgery , vol.160 , Issue.4 , pp. 405-409
    • Shah, J.P.1
  • 7
    • 41949091830 scopus 로고    scopus 로고
    • Molecular-targeted therapies in the treatment of squamous cell carcinomas of the head and neck
    • DOI 10.1097/CCO.0b013e3282f9b575, PII 0000162220080500000004
    • Le Tourneau C, Siu L. Molecular-targeted therapies in the treatment of squamous cell carcinomas of the head and neck. Curr Opin Oncol 2008; 20:256-263. (Pubitemid 351507544)
    • (2008) Current Opinion in Oncology , vol.20 , Issue.3 , pp. 256-263
    • Le Tourneau, C.1    Siu, L.L.2
  • 9
    • 34250180582 scopus 로고    scopus 로고
    • Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy
    • DOI 10.1200/JCO.2006.06.7447
    • Vermorken JB, Trigo J, Hitt R, Koralewski P, Diaz-Rubio E, Rolland F, et al. Open label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy. J Clin Oncol 2007; 25:2171-2177. (Pubitemid 46954639)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.16 , pp. 2171-2177
    • Vermorken, J.B.1    Trigo, J.2    Hitt, R.3    Koralewski, P.4    Diaz-Rubio, E.5    Rolland, F.6    Knecht, R.7    Amellal, N.8    Schueler, A.9    Baselga, J.10
  • 10
    • 33144482904 scopus 로고    scopus 로고
    • Molecular markers of head and neck squamous cell carcinoma: Promising signs in need of prospective evaluation
    • DOI 10.1002/hed.20326
    • Lothaire P, de Azambuja E, Dequanter D, Lalami Y, Sotiriou C, Andry G, et al. Molecular markers of head and neck squamous cell carcinoma: promising signs in need of prospective evaluation. Head Neck 2006; 28:256-269. (Pubitemid 43269893)
    • (2006) Head and Neck , vol.28 , Issue.3 , pp. 256-269
    • Lothaire, P.1    De Azambuja, E.2    Dequanter, D.3    Lalami, Y.4    Sotiriou, C.5    Andry, G.6    Castro Jr., G.7    Awada, A.8
  • 11
    • 68849108871 scopus 로고    scopus 로고
    • Current and potential inflammation targeted therapies in head and neck cancer
    • Wang F, Arun P, Friedman J, Chen Z, Waes CV. Current and potential inflammation targeted therapies in head and neck cancer. Curr Opin Pharmacol 2009; 9:389-395.
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 389-395
    • Wang, F.1    Arun, P.2    Friedman, J.3    Chen, Z.4    Waes, C.V.5
  • 12
    • 62349132266 scopus 로고    scopus 로고
    • Targeting mammalian target of rapamycin by rapamycin prevents tumor progression in an oral-specific chemical carcinogenesis model
    • Czerninski R, Amornphimoltham P, Patel V, Molinolo A, Gutkind J. Targeting mammalian target of rapamycin by rapamycin prevents tumor progression in an oral-specific chemical carcinogenesis model. Cancer Prev Res 2009; 2:27-36.
    • (2009) Cancer Prev Res , vol.2 , pp. 27-36
    • Czerninski, R.1    Amornphimoltham, P.2    Patel, V.3    Molinolo, A.4    Gutkind, J.5
  • 13
  • 14
    • 2442659162 scopus 로고    scopus 로고
    • Preclinical evaluation of the homo-aza-steroid ester 13β-hydroxy- 13α-amino-13,17-seco-5α-androstan-17-oic-13, 17-lactam-p-bis(2- chloroethyl)aminophenoxy acetate for the treatment of malignant melanoma
    • Trafalis DT, Camoutsis C, Karamanakos P, Arvanitis A, Tegou E, Ziras N, et al. Preclinical evaluation of the homo-aza-steroid ester 13beta-hydroxy- 13alpha-amino-13, 17-seco-5alpha-androstan-17-oic-13, 17-lactam-p-bis (2-chloroethyl)amino phenoxy acetate for the treatment of malignant melanoma. J BUON 2007; 8:333-339. (Pubitemid 38660085)
    • (2003) Journal of B.U.ON. , vol.8 , Issue.4 , pp. 333-339
    • Trafalis, D.T.P.1    Camoutsis, Ch.2    Karamanakos, P.3    Arvanitis, A.4    Tegou, E.5    Ziras, N.6    Athanassiou, A.E.7
  • 17
    • 34548428839 scopus 로고    scopus 로고
    • Meta-Analyses of Chemotherapy in Head and Neck Cancer (MACH-NC): An Update
    • DOI 10.1016/j.ijrobp.2007.04.088, PII S0360301607009960
    • Pignon J, Le Maître A, Bourhis J. MACH-NC Collaborative Group. Meta-Analyses of Chemotherapy in Head and Neck Cancer (MACH-NC): an update. Int J Radiat Oncol Biol Phys 2007; 69:S112-S114. (Pubitemid 47369400)
    • (2007) International Journal of Radiation Oncology Biology Physics , vol.69 , Issue.2 SUPPL.
    • Pignon, J.-P.1    Le Maitre, A.2    Bourhis, J.3
  • 18
    • 33644516280 scopus 로고    scopus 로고
    • A meta-analysis of hyperfractionated and accelerated radiotherapy and combined chemotherapy and radiotherapy regimens in unresected locally advanced squamous cell carcinoma of the head and neck
    • Budach W, Hehr T, Budach V, Belka C, Dietz K. A meta-analysis of hyperfractionated and accelerated radiotherapy and combined chemotherapy and radiotherapy regimens in unresected locally advanced squamous cell carcinoma of the head and neck. BMC. Cancer 2006; 6:28.
    • (2006) BMC. Cancer , vol.6 , pp. 28
    • Budach, W.1    Hehr, T.2    Budach, V.3    Belka, C.4    Dietz, K.5
  • 19
    • 36148940637 scopus 로고    scopus 로고
    • High-dose cisplatin concurrent to conventionally delivered radiotherapy is associated with unacceptable toxicity in unresectable, non-metastatic stage IV head and neck squamous cell carcinoma
    • DOI 10.1007/s00405-007-0395-9
    • De Castro G Jr, Snitcovsky IM, Gebrim EM, Leitão GM, Nadalin W, Ferraz AR, et al. High dose cisplatin concurrent to conventionally delivered radiotherapy is associated with unacceptable toxicity in unresectable, non-metastatic stage IV head and neck squamous cell carcinoma. Eur Arch Otorhinolaryngol 2007; 264:1475-1482. (Pubitemid 350112409)
    • (2007) European Archives of Oto-Rhino-Laryngology , vol.264 , Issue.12 , pp. 1475-1482
    • De Castro Jr., G.1    Snitcovsky, I.M.L.2    Gebrim, E.M.M.S.3    Leitao, G.M.4    Nadalin, W.5    Ferraz, A.R.6    Federico, M.H.H.7
  • 21
    • 0035116241 scopus 로고    scopus 로고
    • Vascular endothelial growth factor family members are differentially regulated by c-erbB signaling in head and neck squamous carcinoma cells
    • DOI 10.1023/A:1006764100867
    • O-charoenrat P, Rhys-Evans P, Modjtahedi H, Eccles SA. Vascular endothelial growth factor family members are differentially regulated by c-erbB signaling in head and neck squamous carcinoma cells. Clin Exp Metastasis 2000; 18:155-161. (Pubitemid 32165249)
    • (2000) Clinical and Experimental Metastasis , vol.18 , Issue.2 , pp. 155-161
    • O-charoenrat, P.1    Rhys-Evans, P.2    Modjtahedi, H.3    Eccles, S.4
  • 22
    • 33646532660 scopus 로고    scopus 로고
    • VEGF is up-regulated by hypoxic stimulation and related to tumour angiogenesis and severity of disease in oral squamous cell carcinoma: In vivo and in vitro studies
    • Shang Z, Li Z, Li Jr. VEGF is up-regulated by hypoxic stimulation and related to tumour angiogenesis and severity of disease in oral squamous cell carcinoma: in vivo and in vitro studies. Int J Oral Maxillofac Surg 2006; 35:533-538.
    • (2006) Int J Oral Maxillofac Surg , vol.35 , pp. 533-538
    • Shang, Z.1    Li, Z.2    Li, J.R.3
  • 23
    • 45949094637 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1alpha expression correlates with vascular endothelial growth factor-C expression and lymphangiogenesis/angiogenesis in oral squamous cell carcinoma
    • Liang X, Yang D, Hu J, Hao X, Gao J, Mao Z. Hypoxia inducible factor-alpha expression correlates with vascular endothelial growth factor-C expression and lymphangiogenesis/angiogenesis in oral squamous cell carcinoma. Anticancer Res 2008; 28:1659-1666. (Pubitemid 351892941)
    • (2008) Anticancer Research , vol.28 , Issue.3 A , pp. 1659-1666
    • Liang, X.1    Yang, D.2    Hu, J.3    Hao, X.4    Gao, J.5    Mao, Z.6
  • 24
    • 23844527898 scopus 로고    scopus 로고
    • A phase i study of erlotinib and bevacizumab for recurrent or metastatic squamous cell carcinoma of the head and neck (HNC)
    • Vokes EE, Cohen EE, Mauer AM, Karrison TG, Wong SJ, Skoog-Sluman LJ, et al. A phase I study of erlotinib and bevacizumab for recurrent or metastatic squamous cell carcinoma of the head and neck (HNC). J Clin Oncol 2005; 23 (16S):5504.
    • (2005) J Clin Oncol , vol.23 , Issue.16 S , pp. 5504
    • Vokes, E.E.1    Cohen, E.E.2    Mauer, A.M.3    Karrison, T.G.4    Wong, S.J.5    Skoog-Sluman, L.J.6
  • 25
    • 36049031069 scopus 로고    scopus 로고
    • Phase II trial of pemetrexed (P) and bevacizumab (B) in patients (pts) with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC): An interim analysis
    • Karamouzis M, Friedland D, Johnson R, Rajasenan K, Branstetter B, Argiris A. Phase II trial of pemetrexed (P) and bevacizumab (B) in patients (pts) with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC): an interim analysis. J Clin Oncol 2007; 25 (18S):6049.
    • (2007) J Clin Oncol , vol.25 , Issue.18 S , pp. 6049
    • Karamouzis, M.1    Friedland, D.2    Johnson, R.3    Rajasenan, K.4    Branstetter, B.5    Argiris, A.6
  • 26
    • 78650227959 scopus 로고    scopus 로고
    • EGFR-PI3K-AKT-mTOR signaling in head and neck squamous cell carcinomas: Attractive targets for molecular-oriented therapy
    • Freudlsperger C, Burnett JR, Friedman JA, Kannabiran VR, Chen Z, Van Waes C. EGFR-PI3K-AKT-mTOR signaling in head and neck squamous cell carcinomas: attractive targets for molecular-oriented therapy. Exp Opin Therap Targ 2011; 15:63-74.
    • (2011) Exp Opin Therap Targ , vol.15 , pp. 63-74
    • Freudlsperger, C.1    Burnett, J.R.2    Friedman, J.A.3    Kannabiran, V.R.4    Chen, Z.5    Van Waes, C.6
  • 28
    • 47249125723 scopus 로고    scopus 로고
    • Differential involvement of ikappab kinases alpha and beta in cytokine-and insulin-induced mammalian target of rapamycin activation determined by akt
    • Dan H, Baldwin A. Differential involvement of IkappaB kinases alpha and beta in cytokine-and insulin-induced mammalian target of rapamycin activation determined by Akt. J Immunol 2008; 180:7582-7589.
    • (2008) J Immunol , vol.180 , pp. 7582-7589
    • Dan, H.1    Baldwin, A.2
  • 30
    • 0042322315 scopus 로고    scopus 로고
    • MTOR as a positive regulator of tumor cell responses to hypoxia
    • Abraham RT. MTOR as a positive regulator of tumor cell responses to hypoxia. Curr Top Microbiol Immunol 2004; 279:299-319.
    • (2004) Curr Top Microbiol Immunol , vol.279 , pp. 299-319
    • Abraham, R.T.1
  • 31
    • 43749116022 scopus 로고    scopus 로고
    • Antiproliferative effects of rapamycin as a single agent and in combination with carboplatin and paclitaxel in head and neck cancer cell lines
    • DOI 10.1007/s00280-007-0609-2
    • Aissat N, Le Tourneau C, Ghoul A, Serova M, Bieche I, Lokiec F, et al. Antiproliferative effects of rapamycin as a single agent and in combination with carboplatin and paclitaxel in head and neck cancer cell lines. Cancer Chemother Pharmacol 2008; 62:305-313. (Pubitemid 351692089)
    • (2008) Cancer Chemotherapy and Pharmacology , vol.62 , Issue.2 , pp. 305-313
    • Aissat, N.1    Le Tourneau, C.2    Ghoul, A.3    Serova, M.4    Bieche, I.5    Lokiec, F.6    Raymond, E.7    Faivre, S.8
  • 33
    • 0023736971 scopus 로고    scopus 로고
    • UKCCCR guidelines for the welfare of animals in experimental neoplasia
    • UKCCCR
    • UKCCCR. UKCCCR guidelines for the welfare of animals in experimental neoplasia. Br J Cancer 1998; 58:109-113.
    • (1998) Br J Cancer , vol.58 , pp. 109-113


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