TG-interacting factor-induced superoxide production from NADPH oxidase contributes to the migration/invasion of urothelial carcinoma

Free Radical Biology and Medicine

Volumn 53, Issue 4, 2012, Pages 769-778

  Huang, Huei Sheng ^a   Liu, Zi Miao ^a   Chen, Pei Chi ^a   Tseng, Hong Yu ^a   Yeh, Bi Wen ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

AKT; Migration; NADPH oxidase; Reactive oxygen species; TG interacting factor; Urothelial carcinoma

Indexed keywords

PROTEIN KINASE B; PROTEIN P67; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SHORT HAIRPIN RNA; SUPEROXIDE; TG INTERACTING FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; CANCER CELL; CELL ACTIVATION; CELL INVASION; CELL MIGRATION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSITIONAL CELL CARCINOMA; UPREGULATION;

CARCINOMA; CELL LINE, TUMOR; CELL MOVEMENT; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; HUMANS; MATRIX METALLOPROTEINASE 2; MEMBRANE GLYCOPROTEINS; NADPH OXIDASE; NEOPLASM INVASIVENESS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; SUPEROXIDES; URINARY BLADDER NEOPLASMS;

EID: 84864401266     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.06.014     Document Type: Article

References (52)

1. A. Jemal, R. Siegel, J. Xu, and E. Ward Cancer statistics, 2010 CA Cancer J. Clin. 60 2010 277 300
2. R.F. Youssef, A.P. Mitra, G. Bartsch Jr, P.A. Jones, D.G. Skinner, and R.J. Cote Molecular targets and targeted therapies in bladder cancer management World J. Urol. 27 2009 9 20
3. A.P. Mitra, and R.J. Cote Molecular pathogenesis and diagnostics of bladder cancer Annu. Rev. Pathol 4 2009 251 285
4. W. Droge Free radicals in the physiological control of cell function Physiol. Rev. 82 2002 47 95
5. K. Bedard, and K.H. Krause The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology Physiol. Rev. 87 2007 245 313
6. W.S. Wu The signaling mechanism of ROS in tumor progression Cancer Metastasis Rev 25 2006 695 705
7. L. Dyrskjot, M. Kruhoffer, T. Thykjaer, N. Marcussen, J.L. Jensen, K. Moller, and T.F. Orntoft Gene expression in the urinary bladder: a common carcinoma in situ gene expression signature exists disregarding histopathological classification Cancer Res. 64 2004 4040 4048
8. M.M. Reddy, M.S. Fernandes, R. Salgia, R.L. Levine, J.D. Griffin, and M. Sattler NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases Leukemia 25 2011 281 289
9. M. Ushio-Fukai, and Y. Nakamura Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy Cancer Lett. 266 2008 37 52
10. E. Bertolino, B. Reimund, D. Wildt-Perinic, and R.G. Clerc A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif J. Biol. Chem. 270 1995 31178 31188
11. D. Wotton, R.S. Lo, S. Lee, and J.A. Massague Smad transcriptional corepressor Cell 97 1999 29 39
12. K.W. Gripp, D. Wotton, M.C. Edwards, E. Roessler, L. Ades, P. Meinecke, A. Richieri-Costa, E.H. Zackai, J. Massague, M. Muenke, and S.J. Elledge Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination Nat. Genet. 25 2000 205 208
13. J. Borlak, T. Meier, R. Halter, R. Spanel, and K. Spanel-Borowski Epidermal growth factor-induced hepatocellular carcinoma: gene expression profiles in precursor lesions, early stage and solitary tumours Oncogene 24 2005 1809 1819
14. Z.L. Hu, J.F. Wen, D.S. Xiao, H. Zhen, and C.Y. Fu Effects of transforming growth interacting factor on biological behaviors of gastric carcinoma cells World J. Gastroenterol. 11 2005 84 88
15. R. Hamid, and S.J. Brandt Transforming growth-interacting factor (TGIF) regulates proliferation and differentiation of human myeloid leukemia cells Mol. Oncol 3 2009 451 463
16. C. Voorter, S. Joos, P.P. Bringuier, M. Vallinga, P. Poddighe, J. Schalken, S. du Manoir, F. Ramaekers, P. Lichter, and A. Hopman Detection of chromosomal imbalances in transitional cell carcinoma of the bladder by comparative genomic hybridization Am. J. Pathol. 146 1995 1341 1354
17. WAF1/CIP1 expression J. Biomed. Sci. 15 2008 333 342
18. H.S. Huang, Z.M. Liu, and D.Y. Hong Blockage of JNK pathway enhances arsenic trioxide-induced apoptosis in human keratinocytes Toxicol. Appl. Pharmacol. 244 2010 234 241
19. Z.M. Liu, J.T. Tseng, D.Y. Hong, and H.S. Huang Suppression of TG-interacting factor sensitizes arsenic trioxide-induced apoptosis in human hepatocellular carcinoma cells Biochem. J. 438 2011 349 358
20. Yeh, B. W.; Wu, W. J.; Li, W. M.; Li, C. C.; Huang, C. N.; Kang, W. Y.; Liu, Z. M.; Huang, H. S. Overexpression of TG-interacting factor is associated with worse prognosis in upper urinary tract urothelial carcinoma. Am. J. Pathol. In press; 2012
21. K. Shimada, M. Nakamura, S. Anai, M. De Velasco, M. Tanaka, K. Tsujikawa, Y. Ouji, and N. Konishi A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression Cancer Res. 69 2009 3157 3164
22. E.Y. Kim, J.M. Seo, C. Kim, J.E. Lee, K.M. Lee, and J.H. Kim BLT2 promotes the invasion and metastasis of aggressive bladder cancer cells through a reactive oxygen species-linked pathway Free Radic. Biol. Med. 49 2010 1072 1081
23. L. Dyrskjot, T. Thykjaer, M. Kruhoffer, J.L. Jensen, N. Marcussen, S. Hamilton-Dutoit, H. Wolf, and T.F. Orntoft Identifying distinct classes of bladder carcinoma using microarrays Nat. Genet. 33 2003 90 96
24. M. Sanchez-Carbayo, N.D. Socci, J. Lozano, F. Saint, and C. Cordon-Cardo Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays J. Clin. Oncol. 24 2006 778 789
25. N. Stransky, C. Vallot, F. Reyal, I. Bernard-Pierrot, S.G. de Medina, R. Segraves, Y. de Rycke, P. Elvin, A. Cassidy, C. Spraggon, A. Graham, J. Southgate, B. Asselain, Y. Allory, C.C. Abbou, D.G. Albertson, J.P. Thiery, D.K. Chopin, D. Pinkel, and F. Radvanyi Regional copy number-independent deregulation of transcription in cancer Nat. Genet. 38 2006 1386 1396
26. K. Kawamura, N. Kamiya, T. Suyama, M. Shimbo, N. Oosumi, H. Suzuki, T. Ueda, T. Tobe, T. Igarashi, H. Ito, and H. Ishikura In situ gelatinolytic activity correlates with tumor progression and prognosis in patients with bladder cancer J. Urol. 172 2004 1480 1484
27. X. Wu, T. Obata, Q. Khan, R.A. Highshaw, R. De Vere White, and C. Sweeney The phosphatidylinositol-3 kinase pathway regulates bladder cancer cell invasion BJU Int. 93 2004 143 150
28. M.A. Knowles, F.M. Platt, R.L. Ross, and C.D. Hurst Phosphatidylinositol 3-kinase (PI3K) pathway activation in bladder cancer Cancer Metastasis Rev. 28 2009 305 316
29. X.R. Wu Urothelial tumorigenesis: a tale of divergent pathways Nat. Rev. Cancer 5 2005 713 725
30. M. Roupret, R. Zigeuner, J. Palou, A. Boehle, E. Kaasinen, R. Sylvester, M. Babjuk, and W. Oosterlinck European guidelines for the diagnosis and management of upper urinary tract urothelial cell carcinomas: 2011 update Eur. Urol. 59 2011 584 594
31. G.A. Brown, J.E. Busby, C.G. Wood, L.L. Pisters, C.P. Dinney, D.A. Swanson, H.B. Grossman, C.A. Pettaway, M.F. Munsell, A.M. Kamat, and S.F. Matin Nephroureterectomy for treating upper urinary tract transitional cell carcinoma: time to change the treatment paradigm? BJU Int. 98 2006 1176 1180
32. K. Nakakuki, I. Imoto, A. Pimkhaokham, Y. Fukuda, Y. Shimada, M. Imamura, T. Amagasa, and J. Inazawa Novel targets for the 18p11.3 amplification frequently observed in esophageal squamous cell carcinomas Carcinogenesis 23 2002 19 24
33. L.J. Marnett Oxyradicals and DNA damage Carcinogenesis 21 2000 361 370
34. L. Behrend, G. Henderson, and R.M. Zwacka Reactive oxygen species in oncogenic transformation Biochem. Soc. Trans. 31 2003 1441 1444
35. T.C. Hsu, M.R. Young, J. Cmarik, and N.H. Colburn Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis Free Radic. Biol. Med. 28 2000 1338 1348
36. D.H. Xie, X.D. Tang, S.J. Xia, J.M. Tan, X.H. Wang, and Y. Cai [Expression of NF-kappa B in human bladder cancer and its clinical significance] Ai Zheng 21 2002 663 667
37. G. Levidou, A.A. Saetta, P. Korkolopoulou, P. Papanastasiou, K. Gioti, P. Pavlopoulos, K. Diamantopoulou, E. Thomas-Tsagli, K. Xiromeritis, and E. Patsouris Clinical significance of nuclear factor (NF)-kappaB levels in urothelial carcinoma of the urinary bladder Virchows Arch. 452 2008 295 304
38. A. Di Carlo, D. Terracciano, A. Mariano, and V. Macchia Urinary gelatinase activities (matrix metalloproteinases 2 and 9) in human bladder tumors Oncol. Rep. 15 2006 1321 1326
39. K. Tominaga, T. Kawahara, T. Sano, K. Toida, Y. Kuwano, H. Sasaki, T. Kawai, S. Teshima-Kondo, and K. Rokutan Evidence for cancer-associated expression of NADPH oxidase 1 (Nox1)-based oxidase system in the human stomach Free Radic. Biol. Med. 43 2007 1627 1638
40. D. Gianni, B. Diaz, N. Taulet, B. Fowler, S.A. Courtneidge, and G.M. Bokoch Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity Sci. Signal. 2009 2:ra54
41. J.K. Maranchie, and Y. Zhan Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma Cancer Res 65 2005 9190 9193
42. T. Mochizuki, S. Furuta, J. Mitsushita, W.H. Shang, M. Ito, Y. Yokoo, M. Yamaura, S. Ishizone, J. Nakayama, A. Konagai, K. Hirose, K. Kiyosawa, and T. Kamata Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells Oncogene 25 2006 3699 3707
43. B. Govindarajan, J.E. Sligh, B.J. Vincent, M. Li, J.A. Canter, B.J. Nickoloff, R.J. Rodenburg, J.A. Smeitink, L. Oberley, Y. Zhang, J. Slingerland, R.S. Arnold, J.D. Lambeth, C. Cohen, L. Hilenski, K. Griendling, M. Martinez-Diez, J.M. Cuezva, and J.L. Arbiser Overexpression of Akt converts radial growth melanoma to vertical growth melanoma J. Clin. Invest. 117 2007 719 729
44. J. Si, X. Fu, J. Behar, J. Wands, D.G. Beer, R.F. Souza, S.J. Spechler, D. Lambeth, and W. Cao NADPH oxidase NOX5-S mediates acid-induced cyclooxygenase-2 expression via activation of NF-kappaB in Barrett's esophageal adenocarcinoma cells J. Biol. Chem. 282 2007 16244 16255
45. H.C. Wang, and S. Choudhary Reactive oxygen species-mediated therapeutic control of bladder cancer Nat. Rev. Urol 8 2011 608 616
46. L.C. Cantley The phosphoinositide 3-kinase pathway Science 296 2002 1655 1657
47. L.C. Kompier, I. Lurkin, M.N. van der Aa, B.W. van Rhijn, T.H. van der Kwast, and E.C. Zwarthoff FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy PLoS One 5 2010 e13821
48. H. Wallerand, Y. Cai, Z.A. Wainberg, I. Garraway, I. Lascombe, G. Nicolle, J.P. Thiery, H. Bittard, F. Radvanyi, and R.R. Reiter Phospho-Akt pathway activation and inhibition depends on N-cadherin or phospho-EGFR expression in invasive human bladder cancer cell lines Urol. Oncol. 28 2010 180 188
49. K.A. Cadwallader, A.M. Condliffe, A. McGregor, T.R. Walker, J.F. White, L.R. Stephens, and E.R. Chilvers Regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3,4,5-trisphosphate accumulation by neutrophil priming agents J. Immunol. 169 2002 3336 3344
50. C.R. Hoyal, A. Gutierrez, B.M. Young, S.D. Catz, J.H. Lin, P.N. Tsichlis, and B.M. Babior Modulation of p47PHOX activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidase Proc. Natl. Acad. Sci. USA 100 2003 5130 5135
51. M. Edderkaoui, C. Nitsche, L. Zheng, S.J. Pandol, I. Gukovsky, and A.S. Gukovskaya NADPH oxidase activation in pancreatic cancer cells is mediated through Akt-dependent up-regulation of p22phox J. Biol. Chem. 286 2011 7779 7787
52. N.R. Leslie, D. Bennett, Y.E. Lindsay, H. Stewart, A. Gray, and C.P. Downes Redox regulation of PI 3-kinase signalling via inactivation of PTEN EMBO J 22 2003 5501 5510