Inhibitory effect of JBP485 on renal excretion of acyclovir by the inhibition of OAT1 and OAT3

European Journal of Pharmaceutical Sciences

Volumn 47, Issue 2, 2012, Pages 341-346

  Ye, Jianghao ^a   Liu, Qi ^a   Wang, Changyuan ^a   Meng, Qiang ^a   Peng, Jinyong ^a   Sun, Huijun ^a   Kaku, Taiichi ^b   Liu, Kexin ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b Japan Bioproducts Industry Co Ltd   (Japan)

Author keywords

Acyclovir; Drug drug interactions; JBP485; Organic anion transporters (OATs); Renal excretion

Indexed keywords

4 AMINOHIPPURIC ACID; ACICLOVIR; CYCLO TRANS 4 LEVO HYDROXYPROLYL LEVO SERINE; DIPEPTIDE; JBP 485; OAT1 PROTEIN; OAT3 PROTEIN; PENICILLIN G; PROTEIN; SERINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; DRUG EFFECT; DRUG INTERACTION; DRUG UPTAKE; EMBRYO; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CLEARANCE; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY; URINARY EXCRETION;

ACYCLOVIR; ANIMALS; ANTIVIRAL AGENTS; DRUG INTERACTIONS; HEK293 CELLS; HUMANS; KIDNEY; MALE; ORGANIC ANION TRANSPORT PROTEIN 1; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; PEPTIDES, CYCLIC; RATS; RATS, WISTAR;

EID: 84864400498     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.06.004     Document Type: Article

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