Identification of a novel cryptochrome differentiating domain required for feedback repression in circadian clock function

Journal of Biological Chemistry

Volumn 287, Issue 31, 2012, Pages 25917-25926

  Khan, Sanjoy K ^a   Xu, Haiyan ^a   Ukai Tadenuma, Maki ^b   Burton, Brittany ^a   Wang, Yongmei ^a   Ueda, Hiroki R ^b,c   Liu, Andrew C ^a  

^a University of Memphis   (United States)

^b RIKEN Center for Biosystems Dynamics Research   (Japan)

^c RIKEN   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ACTIVITY; BIOCHEMICAL STUDIES; CARBOXYL-TERMINAL; CELL-BASED; CIRCADIAN CLOCK; CIRCADIAN RHYTHMS; CRY PROTEINS; CRYPTOCHROMES; DOMAIN STRUCTURE; FUNCTIONAL ASSAYS; GENETIC COMPLEMENTATION; HELICAL DOMAINS; KINETIC MEASUREMENT; MECHANISTIC STUDIES; NEGATIVE FEEDBACK LOOP; PERIOD LENGTH; PHOTOLYASES; REAL TIME; TRANSCRIPTIONAL REPRESSION; TRANSCRIPTIONAL REPRESSORS;

PROTEINS;

CLOCKS;

CRYPTOCHROME 1; CRYPTOCHROME 2;

ALPHA HELIX; AMINO ACID ANALYSIS; ANIMAL CELL; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; EMBRYO; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION;

AMINO ACID MOTIFS; CIRCADIAN CLOCKS; CRYPTOCHROMES; FEEDBACK, PHYSIOLOGICAL; FIBROBLASTS; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION; STRUCTURAL HOMOLOGY, PROTEIN; TRANSCRIPTION, GENETIC;

MAMMALIA;

EID: 84864394571     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.368001     Document Type: Article

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