Different signaling mechanisms are involved in the norepinephrine- stimulated TORC1 and TORC2 nuclear translocation in rat pinealocytes

Endocrinology

Volumn 153, Issue 8, 2012, Pages 3839-3849

  McTague, J ^a   Amyotte, N ^a   Kanyo, R ^a   Ferguson, M ^a   Chik, C L ^a   Ho, A K ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; ACTIVATING TRANSCRIPTION FACTOR 4; ALPHA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; CYCLIC AMP; CYCLOSPORIN; NORADRENALIN; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; GENE TRANSLOCATION; GENETIC TRANSCRIPTION; MALE; NONHUMAN; PINEALOCYTE; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; RAT;

ANIMALS; BLOTTING, WESTERN; CELL NUCLEUS; CELLS, CULTURED; MALE; NOREPINEPHRINE; PINEAL GLAND; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 84864383654     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2012-1315     Document Type: Article

References (40)

1. Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, Goodman RH 1993 Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365:855-859 (Pubitemid 23341031)
2. Gonzalez GA, Montminy MR 1989 Cyclic AMP stimulates somatostatin gene transcription by phoshorylation of CREBat serine 133. Cell 59:675-680 (Pubitemid 19282874)
3. Mayr B, Montminy M 2001 Transcriptional regulation by the phosphorylation-dependent factor CREB. Nat Rev Mol Cell Biol 2:599-609 (Pubitemid 33674011)
4. Vo N, Goodman RH 2001 CREB binding protein and p300 in transcriptional regulation. J Biol Chem 276:13505-13508
5. Gau D, Lemberger T, von Gall C, Kretz O, Le Minh N, Gass P, Schmid W, Schibler U, Korf HW, Schütz G 2002 Phosphorylation of CREB Ser142 regulates light-induced phase shifts of the circadian clock. Neuron 34:245-253 (Pubitemid 34442567)
6. Dwarki VJ, Montminy M, Verma IM 1990 Both the basic region and the 'leucine zipper' domain of the cyclicAMPresponse element binding (CREB) protein are essential for transcriptional activation. EMBO J 9:225-232
7. Schumacher MA, Goodman RH, Brennan RG 2000 The structure of a CREB bZIP-somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding. J Biol Chem 275:35242-35247
8. Conkright MD, Canettieri G, Screaton R, Guzman E, Miraglia L, Hogenesch JB, Montminy M 2003 TORCs: transducers of regulated CREB activity. Mol Cell 12:413-423 (Pubitemid 37238928)
9. Koo SH, Flechner L, Qi L, Zhang X, Screaton RA, Jeffries S, Hedrick S, Xu W, Boussouar F, Brindle P, Takemori H, Montminy M 2005 The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature 437:1109-1111
10. Dentin R, Liu Y, Koo SH, Hedrick S, Vargas T, Heredia J, Yates 3rd J, Montminy M 2007 Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2. Nature 449:366-369 (Pubitemid 47443476)
11. Altarejos JY, Montminy M 2011 CREB and the CRTC co-activators: sensors for hormonal and metabolic signals. Nat Rev Mol Cell Biol 12:141-151
12. Wang B, Goode J, Best J, Meltzer J, Schilman PE, Chen J, Garza D, Thomas JB, Montminy M 2008 The insulin-regulated CREB coactivator TORC promotes stress resistance. Cell Metab 7:434-444 (Pubitemid 351598021)
13. Kovács KA, Steullet P, Steinmann M, Do KQ, Magistretti PJ, Halfon O, Cardinaux JR 2007 TORC1 is a calcium- and cAMP-sensitive coincidence detector involved in hippocampal long-term synaptic plasticity. Proc Natl Acad Sci USA 104:4700-4705 (Pubitemid 47186288)
14. Liu Y, Coello AG, Grinevich V, Aguilera G 2010 Involvement of transducer of regulated cAMP response element-binding protein activity on corticotrophin releasing hormone transcription. Endocrinology 151:1109-1118
15. Bittinger MA, McWhinnie E, Meltzer J, Iourgenko V, Latario B, Liu X, Chen CH, Song C, Garza D, Labow M 2004 Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins. Curr Biol 14:2156-2161 (Pubitemid 39623199)
16. Takemori H, Kajimura J, Okamoto M 2007 TORC-SIK cascade regulates CREB activity through the basic leucine zipper domain. FEBS J 274:3202-3209 (Pubitemid 47024984)
17. Screaton RA, Conkright MD, Katoh Y, Best JL, Canettieri G, Jeffries S, Guzman E, Niessen S, Yates 3rd JR, Takemori H, Okamoto M, Montminy M 2004 The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector. Cell 119:61-74 (Pubitemid 39349320)
18. Klein DC, Berg GR, Weller J 1970 Melatonin synthesis: adenosine 3′5′-monophosphate and norepinephrine stimulate N-acetyltransferase. Science 168:979-980
19. Chik CL, Ho AK 1989 Multiple receptor regulation of cyclic nucleotides in rat pinealocytes. Prog Biophys Mol Biol 53:197-203
20. 1-Adrenoceptor activation elevates cytosolic calcium in rat pinealocytes by increasing net influx. J Biol Chem 262:741-745
21. Roseboom PH, Klein DC 1995 Norepinephrine stimulation of pineal cyclicAMPresponse element-binding protein phosphorylation: primary role of a β-adrenergic receptor/cyclic AMP mechanism. Mol Pharmacol 47:439-449
22. Klein DC 1985 Photoneural regulation of the mammalian pineal gland. Photoperiodism, melatonin and the pineal. Ciba Found Symp 117:38-56
23. Maronde E, Schomerus C, Stehle JH, Korf HW 1997 Control of CREB phosphorylation and its role for induction of melatonin synthesis in rat pinealocytes. Biol Cell 89:505-511 (Pubitemid 28209698)
24. Baler R, Covington S, Klein DC 1997 The rat arylalkylamine N-acetyltransferase gene promoter. cAMP activation via a cAMP-responsive element-CCAAT complex. J Biol Chem 272:6979-6985 (Pubitemid 27166398)
25. Bailey MJ, Coon SL, Carter DA, Humphries A, Kim JS, Shi Q, Gaildrat P, Morin F, Ganguly S, Hogenesch JB, Weller JL, Rath MF, Møller M, Baler R, Sugden D, Rangel ZG, Munson PJ, Klein DC 2009 Night/day changes in pineal expression of>600 genes: Central role of adrenergic/cAMP signaling. J Biol Chem 284:7606-7622
26. Roseboom PH, Coon SL, Baler R, McCune SK, Weller JL, KleinDC 1996 Melatonin synthesis: analysis of the more than 150-fold nocturnal increase in serotonin N-acetyltransferase messenger ribonucleic acid in the rat pineal gland. Endocrinology 137:3033-3045
27. Klein DC, Coon SL, Roseboom PH, Weller JL, Bernard M, Gastel JA, Zatz M, Iuvone PM, Rodriguez IR, Bégay V, Falcón J, Cahill GM, Cassone VM, Baler R 1997 The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland. Recent Prog Horm Res 52:307-358
28. Kanyo R, Amyotte N, McTague J, Chik CL, Ho AK 2011 Adrenergic regulation of the distribution of transducer of regulated cAMP-response element-binding protein (TORC2) in rat pinealocytes. Endocrinology 152:3440-3450
29. Kanyo R, Price DM, Chik CL, Ho AK 2009 Salt-inducible kinase 1 in the rat pinealocyte: adrenergic regulation and role in arylalklyamine N-acetyltransferase gene transcription. Endocrinology 150: 4221-4230
30. Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
31. Ho AK, Chik CL 2000 Adrenergic regulation of mitogen-activated protein kinase in rat pinealocytes: opposing effects of protein kinase A and protein kinase G. Endocrinology 141:4496-4502 (Pubitemid 32055126)
32. 2+-channel currents: inhibition by a β-adrenergic agonist and pituitary adenylate cyclaseactivating polypeptide (PACAP) in rat pinealocytes. J Neurochem 68:1078-1087
33. Chik CL, Wloka MT, Price DM, Ho AK 2007 The role of repressor proteins in the adrenergic induction of type II iodothyronine deiodinase in rat pinealocytes. Endocrinology 148:3523-3531 (Pubitemid 46996998)
34. Ganguly S, Weller JL, Ho A, Chemineau P, Malpaux B, Klein DC 2005 Melatonin synthesis: 14-3-3-dependent activation and inhibition of arylalkylamine N-acetyltransferase mediated by phosphoserine-205. Proc Natl Acad Sci USA 102:1222-1227 (Pubitemid 40170753)
35. Price DM, Chik CL, Ho AK 2004 Norepinephrine induction of mitogen-activated protein kinase phosphatase-1 expression in rat pinealocytes: distinct roles of α- and β-adrenergic receptors. Endocrinology 145:5723-5733 (Pubitemid 39564614)
36. Oliver CJ, Shenolikar S 1998 Physiologic importance of protein phosphatase inhibitors. Front Biosci 3:D961-D972
37. Ho AK, Chik CL 1995 Phosphatase inhibitors potentiate adrenergic-stimulated cAMP and cGMP production in rat pinealocytes. Am J Physiol 268:E458-E466
38. Letz B, Schomerus C, Maronde E, Korf HW, Korbmacher C 1997 Stimulation of a nicotinic ACh receptor causes depolarization and activation of L-type Ca2+ channels in rat pinealocytes. J Physiol 499:329-340 (Pubitemid 27132395)
39. Klein DC, Sugden D, Weller JL 1983 Postsynaptic α-adrenergic receptors potentiate the β-adrenergic stimulation of pineal serotonin N-acetyltransferase. Proc Natl Acad Sci USA 80:599-603 (Pubitemid 13174650)
40. Yu L, Schaad NC, Klein DC 1993 Calcium potentiates cyclic AMP stimulation of pineal arylalkylamine N-acetyltransferase. J Neurochem 60:1436-1443 (Pubitemid 23088320)