Studies on the roles of clathrin-mediated membrane trafficking and zinc transporter cis4 in the transport of GPI-anchored proteins in fission yeast

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Jaiseng, Wurentuya ^b   Fang, Yue ^a,b   Ma, Yan ^b   Sugiura, Reiko ^c   Kuno, Takayoshi ^a,b  

^a CHINA MEDICAL UNIVERSITY   (China)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KINKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CLATHRIN; DODECYL SULFATE SODIUM; GENOMIC DNA; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN AAH3; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN ECM33; GPI ANCHORED PROTEIN THAT SUPPRESS THE ZINC TRANSPORTER DELETION 2; MAGNESIUM CHLORIDE; TACROLIMUS; UNCLASSIFIED DRUG; ZINC ION; ZINC TRANSPORTER; ZINC TRANSPORTER CIS4;

AAH3 GENE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CELL MIGRATION; CELL NUCLEUS MEMBRANE; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DELETION MUTANT; ECM33 GENE; ENDOPLASMIC RETICULUM; ENDOSOME; GENE; GENE INTERACTION; GENE ISOLATION; GENE OVEREXPRESSION; GOLGI COMPLEX; GPI ANCHORED PROTEIN THAT SUPPRESS THE ZINC TRANSPORTER DELETION 2 GENE; IN VIVO STUDY; MEMBRANE TRANSPORT; NONHUMAN; PHENOTYPE; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; SCHIZOSACCHAROMYCES POMBE; SEQUENCE ANALYSIS; TEMPERATURE SENSITIVITY; WILD TYPE;

CARRIER PROTEINS; CATION TRANSPORT PROTEINS; CELL MEMBRANE; CLATHRIN; GENES, FUNGAL; INTRACELLULAR SPACE; PHENOTYPE; PROTEIN TRANSPORT; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SEQUENCE DELETION;

SCHIZOSACCHAROMYCETACEAE;

EID: 84864374106     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041946     Document Type: Article

References (43)

1. Lisanti MP, Rodriguez-Boulan E, Saltiel AR, (1990) Emerging functional roles for the glycosyl-phosphatidylinositol membrane protein anchor. J Membr Biol 117: 1-10.
2. Kapteyn JC, Van Den Ende H, Klis FM, (1999) The contribution of cell wall proteins to the organization of the yeast cell wall. Biochim Biophys Acta 1426: 373-383.
3. Kinoshita T, Ohishi K, Takeda J, (1997) GPI-anchor synthesis in mammalian cells: genes, their products, and a deficiency. J Biochem 122: 251-257.
4. Li F, Palecek SP, (2008) Distinct domains of the Candida albicans adhesin Eap1p mediate cell-cell and cell-substrate interactions. Microbiology 154: 1193-1203.
5. Fujita M, Kinoshita T, (2010) Structural remodeling of GPI anchors during biosynthesis and after attachment to proteins. FEBS Lett 584: 1670-1677.
6. Fujita M, Kinoshita T, (2012) GPI-anchor remodeling: Potential functions of GPI-anchors in intracellular trafficking and membrane dynamics. Biochim Biophys Acta.
7. Caro LH, Tettelin H, Vossen JH, Ram AF, van den Ende H, et al. (1997) In silicio identification of glycosyl-phosphatidylinositol-anchored plasma-membrane and cell wall proteins of Saccharomyces cerevisiae. Yeast 13: 1477-1489.
8. Fujita M, Jigami Y, (2008) Lipid remodeling of GPI-anchored proteins and its function. Biochim Biophys Acta 1780: 410-420.
9. De Groot PW, Hellingwerf KJ, Klis FM, (2003) Genome-wide identification of fungal GPI proteins. Yeast 20: 781-796.
10. Yada T, Sugiura R, Kita A, Itoh Y, Lu Y, et al. (2001) Its8, a fission yeast homolog of Mcd4 and Pig-n, is involved in GPI anchor synthesis and shares an essential function with calcineurin in cytokinesis. J Biol Chem 276: 13579-13586.
11. Fang Y, Sugiura R, Ma Y, Yada-Matsushima T, Umeno H, et al. (2008) Cation diffusion facilitator Cis4 is implicated in Golgi membrane trafficking via regulating zinc homeostasis in fission yeast. Mol Biol Cell 19: 1295-1303.
12. Takada H, Nishida A, Domae M, Kita A, Yamano Y, et al. (2010) The cell surface protein gene ecm33+ is a target of the two transcription factors Atf1 and Mbx1 and negatively regulates Pmk1 MAPK cell integrity signaling in fission yeast. Mol Biol Cell 21: 674-685.
13. Morita T, Tanaka N, Hosomi A, Giga-Hama Y, Takegawa K, (2006) An alpha-amylase homologue, aah3, encodes a GPI-anchored membrane protein required for cell wall integrity and morphogenesis in Schizosaccharomyces pombe. Biosci Biotechnol Biochem 70: 1454-1463.
14. Iwaki T, Morita T, Tanaka N, Giga-Hama Y, Takegawa K, (2007) Loss of a GPI-anchored membrane protein Aah3p causes a defect in vacuolar protein sorting in Schizosaccharomyces pombe. Biosci Biotechnol Biochem 71: 623-626.
15. Moreno-Ruiz E, Ortu G, de Groot PW, Cottier F, Loussert C, et al. (2009) The GPI-modified proteins Pga59 and Pga62 of Candida albicans are required for cell wall integrity. Microbiology 155: 2004-2020.
16. Fujita M, Yoko OT, Jigami Y, (2006) Inositol deacylation by Bst1p is required for the quality control of glycosylphosphatidylinositol-anchored proteins. Mol Biol Cell 17: 834-850.
17. Kita A, Sugiura R, Shoji H, He Y, Deng L, et al. (2004) Loss of Apm1, the micro1 subunit of the clathrin-associated adaptor-protein-1 complex, causes distinct phenotypes and synthetic lethality with calcineurin deletion in fission yeast. Mol Biol Cell 15: 2920-2931.
18. Sugiura R, Toda T, Shuntoh H, Yanagida M, Kuno T, (1998) pmp1+, a suppressor of calcineurin deficiency, encodes a novel MAP kinase phosphatase in fission yeast. EMBO J 17: 140-148.
19. Ma Y, Sugiura R, Koike A, Ebina H, Sio SO, et al. (2011) Transient receptor potential (TRP) and Cch1-Yam8 channels play key roles in the regulation of cytoplasmic Ca2+ in fission yeast. PLoS One 6: e22421.
20. Cheng H, Sugiura R, Wu W, Fujita M, Lu Y, et al. (2002) Role of the Rab GTP-binding protein Ypt3 in the fission yeast exocytic pathway and its connection to calcineurin function. Mol Biol Cell 13: 2963-2976.
21. Zhang Y, Sugiura R, Lu Y, Asami M, Maeda T, et al. (2000) Phosphatidylinositol 4-phosphate 5-kinase Its3 and calcineurin Ppb1 coordinately regulate cytokinesis in fission yeast. J Biol Chem 275: 35600-35606.
22. Powner D, Davey J, (1998) Activation of the kexin from Schizosaccharomyces pombe requires internal cleavage of its initially cleaved prosequence. Mol Cell Biol 18: 400-408.
23. Ma Y, Takeuchi M, Sugiura R, Sio SO, Kuno T, (2009) Deletion mutants of AP-1 adaptin subunits display distinct phenotypes in fission yeast. Genes Cells 14: 1015-1028.
24. Muniz M, Morsomme P, Riezman H, (2001) Protein sorting upon exit from the endoplasmic reticulum. Cell 104: 313-320.
25. Mayor S, Riezman H, (2004) Sorting GPI-anchored proteins. Nat Rev Mol Cell Biol 5: 110-120.
26. Watanabe R, Riezman H, (2004) Differential ER exit in yeast and mammalian cells. Curr Opin Cell Biol 16: 350-355.
27. Simons K, van Meer G, (1988) Lipid sorting in epithelial cells. Biochemistry 27: 6197-6202.
28. Castillon GA, Watanabe R, Taylor M, Schwabe TM, Riezman H, (2009) Concentration of GPI-anchored proteins upon ER exit in yeast. Traffic 10: 186-200.
29. Rivier AS, Castillon GA, Michon L, Fukasawa M, Romanova-Michaelides M, et al. (2010) Exit of GPI-anchored proteins from the ER differs in yeast and mammalian cells. Traffic 11: 1017-1033.
30. Wang W, Ferro-Novick S, (2002) A Ypt32p exchange factor is a putative effector of Ypt1p. Mol Biol Cell 13: 3336-3343.
31. Jedd G, Mulholland J, Segev N, (1997) Two new Ypt GTPases are required for exit from the yeast trans-Golgi compartment. J Cell Biol 137: 563-580.
32. Benli M, Doring F, Robinson DG, Yang X, Gallwitz D, (1996) Two GTPase isoforms, Ypt31p and Ypt32p, are essential for Golgi function in yeast. EMBO J 15: 6460-6475.
33. Sevlever D, Mann KJ, Medof ME, (2001) Differential effect of 1,10-phenanthroline on mammalian, yeast, and parasite glycosylphosphatidylinositol anchor synthesis. Biochem Biophys Res Commun 288: 1112-1118.
34. Mann KJ, Sevlever D, (2001) 1,10-Phenanthroline inhibits glycosylphosphatidylinositol anchoring by preventing phosphoethanolamine addition to glycosylphosphatidylinositol anchor precursors. Biochemistry 40: 1205-1213.
35. Toda T, Dhut S, Superti-Furga G, Gotoh Y, Nishida E, et al. (1996) The fission yeast pmk1+ gene encodes a novel mitogen-activated protein kinase homolog which regulates cell integrity and functions coordinately with the protein kinase C pathway. Mol Cell Biol 16: 6752-6764.
36. Moreno S, Klar A, Nurse P, (1991) Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol 194: 795-823.
37. Beach D, Piper M, Nurse P, (1982) Construction of a Schizosaccharomyces pombe gene bank in a yeast bacterial shuttle vector and its use to isolate genes by complementation. Mol Gen Genet 187: 326-329.
38. Ma Y, Sugiura R, Saito M, Koike A, Sio SO, et al. (2007) Six new amino acid-auxotrophic markers for targeted gene integration and disruption in fission yeast. Curr Genet 52: 97-105.
39. Rothstein RJ, (1983) One-step gene disruption in yeast. Methods Enzymol 101: 202-211.
40. Kim DU, Hayles J, Kim D, Wood V, Park HO, et al. (2010) Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe. Nat Biotechnol 28: 617-623.
41. He Y, Sugiura R, Ma Y, Kita A, Deng L, et al. (2006) Genetic and functional interaction between Ryh1 and Ypt3: two Rab GTPases that function in S. pombe secretory pathway. Genes Cells 11: 207-221.
42. Fang Y, Imagawa K, Zhou X, Kita A, Sugiura R, et al. (2009) Pleiotropic phenotypes caused by an opal nonsense mutation in an essential gene encoding HMG-CoA reductase in fission yeast. Genes Cells 14: 759-771.
43. Sio SO, Suehiro T, Sugiura R, Takeuchi M, Mukai H, et al. (2005) The role of the regulatory subunit of fission yeast calcineurin for in vivo activity and its relevance to FK506 sensitivity. J Biol Chem 280: 12231-12238.