Sensitization of human pancreatic cancer cells harboring mutated K-ras to apoptosis

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Shen, Ling ^a   Kim, Sung Hoon ^b   Chen, Chang Yan ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Kyung Hee University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; ACETYLCYSTEINE; CASPASE 3; K RAS PROTEIN; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN KINASE C; PROTEIN P73; PUMA PROTEIN; RAS PROTEIN; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CHEMOSENSITIZATION; CONCENTRATION RESPONSE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE; GENE EXPRESSION REGULATION; GENE MUTATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; ONCOGENE K RAS; PANCREAS CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PUMA GENE; UPREGULATION;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; DNA-BINDING PROTEINS; HUMANS; MUTATION; NUCLEAR PROTEINS; ONCOGENE PROTEIN P21(RAS); PANCREATIC NEOPLASMS; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEINS;

EID: 84864366177     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040435     Document Type: Article

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