PDF receptor signaling in Caenorhabditis elegans modulates locomotion and egg-laying

Molecular and Cellular Endocrinology

Volumn 361, Issue 1-2, 2012, Pages 232-240

  Meelkop, Ellen ^a   Temmerman, Liesbet ^a   Janssen, Tom ^a   Suetens, Nick ^a   Beets, Isabel ^a   Van Rompay, Liesbeth ^a   Shanmugam, Nilesh ^b   Husson, Steven J ^a   Schoofs, Liliane ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Caenorhabditis elegans; Egglaying; Locomotion; PDF; Pigment dispersing factor; Reproduction

Indexed keywords

NEUROPEPTIDE RECEPTOR; PDF RECEPTOR; UNCLASSIFIED DRUG;

ALLELE; ANIMAL EXPERIMENT; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; EGG LAYING; GENE; LOCOMOTION; LOSS OF FUNCTION MUTATION; MUSCLE; NERVE CELL; NONHUMAN; PDF 1 GENE; PDF 2 GENE; PDFR 1 GENE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; BEHAVIOR, ANIMAL; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; GENE KNOCKOUT TECHNIQUES; LOCOMOTION; MUTATION; OVIPOSITION; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; SWIMMING;

EID: 84864352942     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.05.001     Document Type: Article

References (46)

1. Bargmann C.I. Neurobiology of the Caenorhabditis elegans genome. Science 1998, 282:2028-2033.
2. Cardoso J.C., Pinto V.C., Vieira F.A., Clark M.S., Power D.M. Evolution of secretin family GPCR members in the metazoa. BMC Evol. Biol. 2006, 6:108.
3. Chalfie M., Sulston J. Developmental genetics of the mechanosensory neurons of Caenorhabditis elegans. Dev. Biol. 1981, 82:358-370.
4. De Bono M., Bargmann C.I. Natural variation in a neuropeptide Y receptor homolog modifies social behavior and food response in C. elegans. Cell 1998, 94:679-689.
5. De Bono M., Maricq A.V. Neuronal substrates of complex behaviors in C. elegans. Annu. Rev. Neurosci. 2005, 28:451-501.
6. Fredriksson R., Schiöth H.B. The repertoire of G-protein-coupled receptors in fully sequenced genomes. Mol. Pharmacol. 2005, 67:1414-1425.
7. Gray J.M., Hill J.J., Bargmann C.I. A circuit for navigation in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 2005, 102:3184-3191.
8. Hamanaka Y., Yasuyama K., Numata H., Shiga S. Synaptic connections between pigment-dispersing factor-immunoreactive neurons and neurons in the pars lateralis of the blow fly Protophormia terraenovae. J. Comp. Neurol. 2005, 491:390-399.
9. Harmar, A.J., 2001. Family-B G-protein-coupled receptors, Gen. Biol. 2.
10. Helfrich-Forster C., Tauber M., Park J.H., Muhlig-Versen M., Schneuwly S., Hofbauer A. Ectopic expression of the neuropeptide pigment-dispersing factor alters behavioral rhythms in Drosophila melanogaster. J. Neurosci. 2000, 20:3339-3353.
11. Husson S.J., Clynen E., Baggerman G., De L.A., Schoofs L. Discovering neuropeptides in Caenorhabditis elegans by two dimensional liquid chromatography and mass spectrometry. Biochem. Biophys. Res. Commun. 2005, 335:76-86.
12. Husson S.J., Clynen E., Baggerman G., De L.A., Schoofs L. Peptidomics of Caenorhabditis elegans: in search of neuropeptides. Commun. Agric. Appl. Biol. Sci. 2005, 70:153-156.
13. Husson S.J., Clynen E., Baggerman G., Janssen T., Schoofs L. Defective processing of neuropeptide precursors in Caenorhabditis elegans lacking proprotein convertase 2 (KPC-2/EGL-3): mutant analysis by mass spectrometry. J. Neurochem. 2006, 98:1999-2012.
14. Husson S.J., Janssen T., Baggerman G., Bogert B., Kahn-Kirby A.H., Ashrafi K., Schoofs L. Impaired processing of FLP and NLP peptides in carboxypeptidase E (EGL-21)-deficient Caenorhabditis elegans as analyzed by mass spectrometry. J. Neurochem. 2007, 102:246-260.
15. Husson S.J., Mertens I., Janssen T., Lindemans M., Schoofs L. Neuropeptidergic signaling in the nematode Caenorhabditis elegans. Prog. Neurobiol. 2007, 82:33-55.
16. Inoue T., Wang M., Ririe T.O., Fernandes J.S., Sternberg P.W. Transcriptional network underlying Caenorhabditis elegans vulval development. Proc. Natl. Acad. Sci. USA 2005, 102:4972-4977.
17. Jacob T.C., Kaplan J.M. The EGL-21 carboxypeptidase E facilitates acetylcholine release at Caenorhabditis elegans neuromuscular junctions. J. Neurosci. 2003, 23:2122-2130.
18. Janssen T., Husson S.J., Lindemans M., Mertens I., Rademakers S., Ver D.K., Geysen J., Jansen G., Schoofs L. Functional characterization of three G protein-coupled receptors for pigment dispersing factors in Caenorhabditis elegans. J. Biol. Chem. 2008, 283:15241-15249.
19. Janssen T., Husson S.J., Meelkop E., Temmerman L., Lindemans M., Verstraelen K., Rademakers S., Mertens I., Nitabach M., Jansen G., Schoofs L. Discovery and characterization of a conserved pigment dispersing factor-like neuropeptide pathway in Caenorhabditis elegans. J. Neurochem. 2009, 111:228-241.
20. Janssen T., Lindemans M., Meelkop E., Temmerman L., Schoofs L. Coevolution of neuropeptidergic signaling systems: from worm to man. Ann. NY Acad. Sci. 2010, 1200:1-14.
21. Kass J., Jacob T.C., Kim P., Kaplan J.M. The EGL-3 proprotein convertase regulates mechanosensory responses of Caenorhabditis elegans. J. Neurosci. 2001, 21:9265-9272.
22. Lesa G.M. Isolation of Caenorhabditis elegans gene knockouts by PCR screening of chemically mutagenized libraries. Nat. Protoc. 2006, 1:2231-2240.
23. Li C. The ever-expanding neuropeptide gene families in the nematode Caenorhabditis elegans. Parasitology 2005, 131(Suppl):S109-S127.
24. Li, C., Kim, K., 2008. Neuropeptides. WormBook, 1-36.
25. Lindemans M., Liu F., Janssen T., Husson S.J., Mertens I., Gade G., Schoofs L. Adipokinetic hormone signaling through the gonadotropin-releasing hormone receptor modulates egg-laying in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 2009, 106:1642-1647.
26. Majmudar, T., Keaveny, E.E., Zhang, J., Shelley, M.J., 2012. Experiments and theory of undulatory locomotion in a simple structured medium. J. R. Soc. Interf. [Epub ahead of print].
27. Meelkop E., Temmerman L., Schoofs L., Janssen T. Signalling through pigment dispersing hormone-like peptides in invertebrates. Prog. Neurobiol. 2011, 93:125-147.
28. Meissner B., Warner A., Wong K., Dube N., Lorch A., McKay S.J., Khattra J., Rogalski T., Somasiri A., Chaudhry I., Fox R.M., Miller D.M., Baillie D.L., Holt R.A., Jones S.J., Marra M.A., Moerman D.G. An integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegans. PLoS Genet. 2009, 2009(5):e1000537.
29. Mertens I., Vandingenen A., Johnson E.C., Shafer O.T., Li W., Trigg J.S., De L.A., Schoofs L., Taghert P.H. PDF receptor signaling in Drosophila contributes to both circadian and geotactic behaviors. Neuron 2005, 48:213-219.
30. Nathoo A.N., Moeller R.A., Westlund B.A., Hart A.C. Identification of neuropeptide-like protein gene families in Caenorhabditis elegans and other species. Proc. Natl. Acad. Sci. USA 2001, 98:14000-14005.
31. Pierce-Shimomura J.T., Chen B.L., Mun J.J., Ho R., Sarkis R., McIntire S.L. Genetic analysis of crawling and swimming locomotory patterns in C. elegans. Proc. Natl. Acad. Sci. USA 2008, 105:20982-20987.
32. Ramot D., Johnson B.E., Berry T.L., Carnell L., Goodman M.B. The Parallel Worm Tracker: a platform for measuring average speed and drug-induced paralysis in nematodes. PLoS ONE 2008, 3:e2208.
33. Rao K.R., Riehm J.P. Pigment-dispersing hormones. Ann. NY Acad. Sci. 1993, 680:78-88.
34. Renn S.C., Park J.H., Rosbash M., Hall J.C., Taghert P.H. A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila. Cell 1999, 99:791-802.
35. Ringstad N., Horvitz H.R. FMRFamide neuropeptides and acetylcholine synergistically inhibit egg-laying by C. elegans. Nat. Neurosci. 2008, 11:1168-1176.
36. Roman, D.L. Traynor, J.R., 2011. Regulators of G-protein signaling (RGS) proteins as drug targets: modulating G-protein-coupled receptor (GPCR) signal transduction. J Med. Chem. [Epub ahead of print].
37. Sawin E.R., Ranganathan R., Horvitz H.R. C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway. Neuron 2000, 26:619-631.
38. Schiöth H.B., Fredriksson R. The GRAFS classification system of G-protein coupled receptors in comparative perspective. Gen. Comp. Endocrinol. 2005, 142:94-101.
39. Segalat L., Elkes D.A., Kaplan J.M. Modulation of serotonin-controlled behaviors by Go in Caenorhabditis elegans. Science 1995, 267:1648-1651.
40. Simonetta S.H., Golombek D.A. An automated tracking system for Caenorhabditis elegans locomotor behavior and circadian studies application. J. Neurosci. Methods 2007, 161:273-280.
41. Temmerman, L., Bogaerts, A., Meelkop, E., Cardoen, D., Boerjan, B., Janssen, T., Schoofs, L., 2011 A proteomic approach to neuropeptide function elucidation. Peptides [Epub ahead of print].
42. The C.elegans Sequencing Consortium Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 1998, 282:2012-2018.
43. Thomas J.H., Robertson H.M. The Caenorhabditis chemoreceptor gene families. BMC Biol. 2008, 6:42.
44. Toma D.P., White K.P., Hirsch J., Greenspan R.J. Identification of genes involved in Drosophila melanogaster geotaxis, a complex behavioral trait. Nat. Genet. 2002, 31:349-353.
45. Vanden Broeck J.V. Insect G protein-coupled receptors and signal transduction. Arch. Insect Biochem. Physiol. 2001, 48:1-12.
46. White J.G., Southgate E., Thomson J.N., Brenner S. The structure of the nervous-system of the nematode Caenorhabditis elegans. Philosophical Transactions of the Royal Society of London Series B-Biological Sciences 1986, 314:1-340.