In utero nicotine exposure promotes M2 activation in neonatal mouse alveolar macrophages

Pediatric Research

Volumn 72, Issue 2, 2012, Pages 147-153

  Wongtrakool, Cherry ^a,b   Grooms, Kora ^a   Ping, Xiao Du ^a   Rivera, Hilda ^a   Ward, Janine ^a   Roser Page, Susanne ^b   Roman, Jesse ^c,d   Brown, Lou Ann S ^a   Gauthier, Theresa W ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ATLANTA VA MEDICAL CENTER   (United States)

^c University of Louisville School of Medicine   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUNGAROTOXIN RECEPTOR; INTERLEUKIN 13; NICOTINE; TOBACCO SMOKE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL FUNCTION; CONTROLLED STUDY; FEMALE; IMMUNOCOMPETENT CELL; IN VITRO STUDY; INFECTION RISK; LUNG ALVEOLUS MACROPHAGE; MALE; MATERNAL SMOKING; MOUSE; NEWBORN; NONHUMAN; PHAGOCYTOSIS; PRENATAL EXPOSURE; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION;

ANIMALS; BLOTTING, WESTERN; BUNGAROTOXINS; CELL LINE; FEMALE; FIBRONECTINS; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOHISTOCHEMISTRY; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NICOTINE; PARACRINE COMMUNICATION; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PULMONARY ALVEOLI; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, NICOTINIC; SMOKING;

EID: 84864332694     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1038/pr.2012.55     Document Type: Article

References (38)

1. Centers for Disease Control and Prevention. Cigarette smoking among adults-United States, 2007. MMWR Morb Mortal Wkly Rep 2008;57:1221-6.
2. D'Angelo D, Williams L, Morrow B, et al. Preconception and interconception health status of women who recently gave birth to a live-born infant-Pregnancy Risk Assessment Monitoring System (PRAMS), United States, 26 reporting areas, 2004. MMWR Surveill Summ 2007;56:1-35.
3. Tong VT, Jones JR, Dietz PM, D'Angelo D, Bombard JM. Trends in smoking before, during, and after pregnancy-pregnancy risk assessment monitoring system (PRAMS), united states, 31 sites, 2000-2005. MMWR Surveill Summ 2009;58:1-29.
4. DiFranza JR, Aligne CA, Weitzman M. Prenatal and postnatal environmental tobacco smoke exposure and children's health. Pediatrics 2004;113(4 Suppl):1007-15. (Pubitemid 38437353)
5. Mercelina-Roumans PE, Breukers RB, Ubachs JM, van Wersch JW. Hematological variables in cord blood of neonates of smoking and nonsmoking mothers. J Clin Epidemiol 1996;49:449-54. (Pubitemid 26149670)
6. Suzuki K, Tanaka T, Kondo N, Minai J, Sato M, Yamagata Z. Is maternal smoking during early pregnancy a risk factor for all low birth weight infants? J Epidemiol 2008;18:89-96.
7. Alarcon A, Pea P, Salas S, Sancha M, Omëca F. Neonatal early onset Escherichia coli sepsis: trends in incidence and antimicrobial resistance in the era of intrapartum antimicrobial prophylaxis. Pediatr Infect Dis J 2004;23:295-9. (Pubitemid 38508879)
8. Cordero L, Rau R, Taylor D, Ayers LW. Enteric gram-negative bacilli bloodstream infections: 17 years' experience in a neonatal intensive care unit. Am J Infect Control 2004;32:189-95. (Pubitemid 38857890)
9. Rehan VK, Wang Y, Sugano S, et al. In utero nicotine exposure alters fetal rat lung alveolar type II cell proliferation, differentiation, and metabolism. Am J Physiol Lung Cell Mol Physiol 2007;292:L323-33. (Pubitemid 46103457)
10. Luck W, Nau H, Hansen R, Steldinger R. Extent of nicotine and cotinine transfer to the human fetus, placenta and amniotic fluid of smoking mothers. Dev Pharmacol Ther 1985;8:384-95. (Pubitemid 16204068)
11. Rehan VK, Asotra K, Torday JS. The effects of smoking on the developing lung: insights from a biologic model for lung development, homeostasis, and repair. Lung 2009;187:281-9.
12. Wongtrakool C, Roser-Page S, Rivera HN, Roman J. Nicotine alters lung branching morphogenesis through the alpha7 nicotinic acetylcholine receptor. Am J Physiol Lung Cell Mol Physiol 2007;293:L611-8. (Pubitemid 47358823)
13. Zhao Z, Reece EA. Nicotine-induced embryonic malformations mediated by apoptosis from increasing intracellular calcium and oxidative stress. Birth Defects Res B Dev Reprod Toxicol 2005;74:383-91. (Pubitemid 41579581)
14. Sekhon HS, Jia Y, Raab R, et al. Prenatal nicotine increases pulmonary alpha7 nicotinic receptor expression and alters fetal lung development in monkeys. J Clin Invest 1999;103:637-47. (Pubitemid 29122416)
15. Martinez FO, Helming L, Gordon S. Alternative activation of macrophages: an immunologic functional perspective. Annu Rev Immunol 2009;27:451-83.
16. Tong VT, Jones JR, Dietz PM, D'Angelo D, Bombard JM. Trends in smoking before, during, and after pregnancy-Pregnancy Risk Assessment Monitoring System (PRAMS), United States, 31 sites, 2000-2005. MMWR Surveill Summ 2009;58:1-29.
17. Pavlov VA, Wang H, Czura CJ, Friedman SG, Tracey KJ. The cholinergic anti-inflammatory pathway: a missing link in neuroimmunomodulation. Mol Med 2003;9:125-34. (Pubitemid 37310949)
18. Su X, Lee JW, Matthay ZA, et al. Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats. Am J Respir Cell Mol Biol 2007;37:186-92. (Pubitemid 47255001)
19. De Simone R, Ajmone-Cat MA, Carnevale D, Minghetti L. Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures. J Neuroinflammation 2005;2:4.
20. Lau PP, Li L, Merched AJ, Zhang AL, Ko KW, Chan L. Nicotine induces proinflammatory responses in macrophages and the aorta leading to acceleration of atherosclerosis in low-density lipoprotein receptor(f/r) mice. Arterioscler Thromb Vasc Biol 2006;26:143-9. (Pubitemid 43732241)
21. Gahring LC, Osborne-Hereford AV, Vasquez-Opazo GA, Rogers SW. Tumor necrosis factor alpha enhances nicotinic receptor up-regulation via a p38MAPK-dependent pathway. J Biol Chem 2008;283:693-9.
22. Gordon SB, Read RC. Macrophage defences against respiratory tract infections. Br Med Bull 2002;61:45-61. (Pubitemid 34477555)
23. Broug-Holub E, Toews GB, van Iwaarden JF, et al. Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival. Infect Immun 1997;65:1139-46. (Pubitemid 27146594)
24. Gratchev A, Guillot P, Hakiy N, et al. Alternatively activated macrophages differentially express fibronectin and its splice variants and the extracellular matrix protein betaIG-H3. Scand J Immunol 2001;53:386-92. (Pubitemid 32275696)
25. Ramirez AM, Wongtrakool C, Welch T, Steinmeyer A, Zoel U, Roman J. Vitamin D inhibition of pro-fibrotic effects of transforming growth factor beta1 in lung fibroblasts and epithelial cells. J Steroid Biochem Mol Biol 2010;118:142-50.
26. Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest 1998;101:890-8. (Pubitemid 28096086)
27. Gauthier TW, Ping XD, Gabelaia L, Brown LA. Delayed neonatal lung macrophage differentiation in a mouse model of in utero ethanol exposure. Am J Physiol Lung Cell Mol Physiol 2010;299:L8-16.
28. Gauldie J, Galt T, Bonniaud P, Robbins C, Kelly M, Warburton D. Transfer of the active form of transforming growth factor-beta 1 gene to newborn rat lung induces changes consistent with bronchopulmonary dysplasia. Am J Pathol 2003;163:2575-84. (Pubitemid 37466498)
29. Vicencio AG, Lee CG, Cho SJ, et al. Conditional overexpression of bioactive transforming growth factor-beta1 in neonatal mouse lung: a new model for bronchopulmonary dysplasia? Am J Respir Cell Mol Biol 2004;31:650-6. (Pubitemid 39587495)
30. Nakanishi H, Sugiura T, Streisand JB, Lonning SM, Roberts JD Jr. TGF-beta-neutralizing antibodies improve pulmonary alveologenesis and vasculogenesis in the injured newborn lung. Am J Physiol Lung Cell Mol Physiol 2007;293:L151-61. (Pubitemid 47080723)
31. Hodge S, Matthews G, Mukaro V, et al. Cigarette smoke-induced changes to alveolar macrophage phenotype and function are improved by treatment with procysteine. Am J Respir Cell Mol Biol 2011;44:673-81.
32. Shaykhiev R, Krause A, Salit J, et al. Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease. J Immunol 2009;183:2867-83.
33. Rowell PP, Hurst HE, Marlowe C, Bennett BD. Oral administration of nicotine: its uptake and distribution after chronic administration to mice. J Pharmacol Methods 1983;9:249-61. (Pubitemid 13035249)
34. Orr-Urtreger A, Gadner FM, Saeki M, et al. Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents. J Neurosci 1997;17:9165-71. (Pubitemid 27498444)
35. Roman J, Ritzenthaler JD, Gil-Acosta A, Rivera HN, Roser-Page S. Nicotine and fibronectin expression in lung fibroblasts: implications for tobacco-related lung tissue remodeling. FASEB J 2004;18:1436-8. (Pubitemid 39561606)
36. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
37. Tomic R, Lassiter CC, Ritzenthaler JD, Rivera HN, Roman J. Anti-tissue remodeling effects of corticosteroids: fluticasone propionate inhibits fibronectin expression in fibroblasts. Chest 2005;127:257-65. (Pubitemid 41724586)
38. Gauthier TW, Ping XD, Harris FL, Wong M, Elbahesh H, Brown LA. Fetal alcohol exposure impairs alveolar macrophage function via decreased glutathione availability. Pediatr Res 2005;57:76-81. (Pubitemid 40039896)