Delayed neonatal lung macrophage differentiation in a mouse model of in utero ethanol exposure

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 299, Issue 1, 2010, Pages

  Gauthier, Theresa W ^a   Ping, Xiao Du ^a   Gabelaia, Levan ^a   Brown, Lou Ann S ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alveolar macrophage; Fetal alcohol; Lung; Prematurity

Indexed keywords

ALCOHOL; CD11B ANTIGEN; CD32 ANTIGEN; S ADENOSYLMETHIONINE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; FEMALE; FETAL ALCOHOL SYNDROME; LIPID PEROXIDATION; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; MOUSE; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PHAGOCYTOSIS; PRIORITY JOURNAL;

ADULT; ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DISEASE MODELS, ANIMAL; ETHANOL; FEMALE; HUMANS; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED C57BL; PHAGOCYTOSIS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS;

EID: 77953488673     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.90609.2008     Document Type: Article

References (36)

1. Arnaout MA. Structure and function of the leukocyte adhesion molecules CD11/CD18. Blood 75: 1037-1050, 1990. (Pubitemid 20086807)
2. Bartram U, Speer CP. The role of transforming growth factor beta in lung development and disease. Chest 125: 754-765, 2004. (Pubitemid 38223659)
3. Bechara RI, Brown LA, Roman J, Joshi PC, Guidot DM. Transforming growth factor beta1 expression and activation is increased in the alcoholic rat lung. Am J Respir Crit Care Med 170: 188-194, 2004. (Pubitemid 38925166)
4. Bellanti JA, Zeligs BJ. Developmental aspects of pulmonary defenses in children. Pediatr Pulmonol Suppl 11: 79-80, 1995.
5. Berclaz PY, Zsengeller Z, Shibata Y, Otake K, Strasbaugh S, Whitsett JA, Trapnell BC. Endocytic internalization of adenovirus, nonspecific phagocytosis, and cytoskeletal organization are coordinately regulated in alveolar macrophages by GM-CSF and PU1. J Immunol 169: 6332-6342, 2002. (Pubitemid 36903481)
6. Bonfield TL, Raychaudhuri B, Malur A, Abraham S, Trapnell BC, Kavuru MS, Thomassen MJ. PU1 regulation of human alveolar macrophage differentiation requires granulocyte-macrophage colony-stimulating factor. Am J Physiol Lung Cell Mol Physiol 285: L1132-L1136, 2003.
7. Brown LA, Harris FL, Guidot DM. Chronic ethanol ingestion potentiates TNF-α-mediated oxidative stress and apoptosis in rat type II cells. Am J Physiol Lung Cell Mol Physiol 281: L377-L386, 2001.
8. Brown LA, Ping XD, Harris FL, Gauthier TW. Glutathione availability modulates alveolar macrophage function in the chronic ethanol-fed rat. Am J Physiol Lung Cell Mol Physiol 292: L824-L832, 2007.
9. Calhoun WJ, Salisbury SM. Heterogeneity in cell recovery and superoxide production in buoyant, density-defined subpopulations of human alveolar macrophages from healthy volunteers and sarcoidosis patients. J Lab Clin Med 114: 682-690, 1989.
10. Chandler DB, Fuller WC, Jackson RM, Fulmer JD. Fractionation of rat alveolar macrophages by isopycnic centrifugation: morphological, cytochemical, biochemical, and functional properties. J Leukoc Biol 39: 371-383, 1986.
11. Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest 101: 890-898, 1998. (Pubitemid 28096086)
12. Fan K, Ruan Q, Sensenbrenner L, Chen B. Transforming growth factor-beta 1 bifunctionally regulates murine macrophage proliferation. Blood 79: 1679-1685, 1992.
13. Fels AO, Cohn ZA. The alveolar macrophage. J Appl Physiol 60: 353-369, 1986.
14. Fitzpatrick AM, Holguin F, Teague WG, Brown LA. Alveolar macrophage phagocytosis is impaired in children with poorly controlled asthma. J Allergy Clin Immunol 121: 1372-1378, 1378.e1-1378.e3, 2008.
15. Franke-Ullmann G, Pfortner C, Walter P, Steinmuller C, Lohmann-Matthes ML, Kobzik L. Characterization of murine lung interstitial macrophages in comparison with alveolar macrophages in vitro. J Immunol 157: 3097-3104, 1996. (Pubitemid 126450070)
16. Gauldie J, Galt T, Bonniaud P, Robbins C, Kelly M, Warburton D. Transfer of the active form of transforming growth factor-beta 1 gene to newborn rat lung induces changes consistent with bronchopulmonary dysplasia. Am J Pathol 163: 2575-2584, 2003. (Pubitemid 37466498)
17. Gauthier TW, Drews-Botsch C, Falek A, Coles C, Brown LA. Maternal alcohol abuse and neonatal infection. Alcohol Clin Exp Res 29: 1035-1043, 2005. (Pubitemid 40934208)
18. Gauthier TW, Manar MH, Brown LA. Is maternal alcohol use a risk factor for early-onset sepsis in the premature newborn? Alcohol 33: 139-145, 2004.
19. Gauthier TW, Ping XD, Harris FL, Wong M, Elbahesh H, Brown LA. Fetal alcohol exposure impairs fetal alveolar macrophage function via decreased glutathione availability. Pediatr Res 57: 76-81, 2005. (Pubitemid 40039896)
20. Gauthier TW, Young PA, Gabelaia L, Tang SM, Ping XD, Harris FL, Brown LA. In utero ethanol exposure impairs defenses against experimental group b streptococcus in the term guinea pig lung. Alcohol Clin Exp Res 33: 300-306, 2009.
21. Hall SL, Sherman MP. Intrapulmonary bacterial clearance of type III group B streptococcus is reduced in preterm compared with term rabbits and occurs independent of antibody. Am Rev Respir Dis 145: 1172-1177, 1992.
22. Han J, Hajjar DP, Tauras JM, Feng J, Gotto AM Jr, Nicholson AC. Transforming growth factor-beta1 (TGF-beta1) and TGF-beta2 decrease expression of CD36, the type B scavenger receptor, through mitogen-activated protein kinase phosphorylation of peroxisome proliferator-activated receptor-gamma. J Biol Chem 275: 1241-1246, 2000. (Pubitemid 30051177)
23. Hance AJ, Douches S, Winchester RJ, Ferrans VJ, Crystal RG. Characterization of mononuclear phagocyte subpopulations in the human lung by using monoclonal antibodies: changes in alveolar macrophage phenotype associated with pulmonary sarcoidosis. J Immunol 134: 284-292, 1985. (Pubitemid 15191510)
24. Holian A, Dauber JH, Diamond MS, Daniele RP. Separation of bronchoalveolar cells from the guinea pig on continuous gradients of Percoll: functional properties of fractionated lung macrophages. J Reticuloendothel Soc 33: 157-164, 1983. (Pubitemid 13131559)
25. Kotecha S. Cytokines in chronic lung disease of prematurity. Eur J Pediatr 155, Suppl 2: S14-17, 1996.
26. Kramer BW, Ikegami M, Moss TJ, Nitsos I, Newnham JP, Jobe AH. Antenatal betamethasone changes cord blood monocyte responses to endotoxin in preterm lambs. Pediatr Res 55: 764-768, 2004. (Pubitemid 38520441)
27. Kramer BW, Ikegami M, Moss TJ, Nitsos I, Newnham JP, Jobe AH. Endotoxin-induced chorioamnionitis modulates innate immunity of monocytes in preterm sheep. Am J Respir Crit Care Med 171: 73-77, 2005. (Pubitemid 40051698)
28. Kwong KY, Niang S, Literat A, Zhu NL, Ramanathan R, Jones CA, Minoo P. Expression of transforming growth factor beta (TGF-b1) by human preterm lung inflammatory cells. Life Sci 79: 2349-2356, 2006. (Pubitemid 44772931)
29. Laskin DL, Weinberger B, Laskin JD. Functional heterogeneity in liver and lung macrophages. J Leukoc Biol 70: 163-170, 2001. (Pubitemid 32751506)
30. Mandrekar P, Catalano D, Dolganiuc A, Kodys K, Szabo G. Inhibition of myeloid dendritic cell accessory cell function and induction of T cell anergy by alcohol correlates with decreased IL-12 production. J Immunol 173: 3398-3407, 2004. (Pubitemid 39142050)
31. McDonald PP, Fadok VA, Bratton D, Henson PM. Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells. J Immunol 163: 6164-6172, 1999.
32. Meyer KC, Powers C, Rosenthal N, Auerbach R. Alveolar macrophage surface carbohydrate expression is altered in interstitial lung disease as determined by lectin-binding profiles. Am Rev Respir Dis 148: 1325-1334, 1993.
33. Moffat FL Jr, Han T, Li ZM, Peck MD, Jy W, Ahn YS, Chu AJ, Bourguignon LY. Supplemental L-arginine HCl augments bacterial phagocytosis in human polymorphonuclear leukocytes PG-26-33. J Cell Physiol 168: 26-33, 1996. (Pubitemid 26233429)
34. Oghiso Y. Morphologic and functional heterogeneity among rat alveolar macrophage fractions isolated by centrifugation on density gradients. J Leukoc Biol 42: 188-196, 1987.
35. Ping XD, Harris FL, Brown LA, Gauthier TW. In vivo dysfunction of the term alveolar macrophage after in utero ethanol exposure. Alcohol Clin Exp Res 31: 308-316, 2007.
36. Prieto J, Eklund A, Patarroyo M. Regulated expression of integrins and other adhesion molecules during differentiation of monocytes into macrophages. Cell Immunol 156: 191-211, 1994.