Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors

Journal of Experimental Medicine

Volumn 209, Issue 6, 2012, Pages 1121-1134

  Xiong, Wei ^a   Cui, Tanxing ^c   Cheng, Kejun ^b   Yang, Fei ^d   Chen, Shao Rui ^e   Willenbring, Dan ^c   Guan, Yun ^d   Pan, Hui Lin ^e   Ren, Ke ^f   Xu, Yan ^c   Zhang, Li ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^f UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA3 GLYCINE RECEPTOR; CANNABIDIOL; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; DEHYDROXYL CANNABIDIOL; DIDESOXYCANNABIDIOL; GLYCINE; GLYCINE RECEPTOR; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC PAIN; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG TARGETING; HETERONUCLEAR SINGLE QUANTUM COHERENCE; INFLAMMATORY PAIN; MALE; MOUSE; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; RECEPTOR AFFINITY; SPINAL CORD; SPINAL CORD DORSAL HORN;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CANNABIDIOL; CELL LINE; CHRONIC PAIN; DINOPROSTONE; HUMANS; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; NEURALGIA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, TERTIARY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLYCINE;

EID: 84864312284     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20120242     Document Type: Article

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