Intrinsic Nucleic Acid-Binding Activity of Chp1 Chromodomain Is Required for Heterochromatic Gene Silencing

Molecular Cell

Volumn 47, Issue 2, 2012, Pages 228-241

  Ishida, Mayumi ^a,b   Shimojo, Hideaki ^c   Hayashi, Aki ^a   Kawaguchi, Rika ^a   Ohtani, Yasuko ^a   Uegaki, Koichi ^d   Nishimura, Yoshifumi ^c   Nakayama, Jun Ichi ^a,b,e  

^a RIKEN Center for Biosystems Dynamics Research   (Japan)

^b KWANSEI GAKUIN UNIVERSITY   (Japan)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

^d NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^e NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; MEMBRANE PROTEIN; NUCLEIC ACID BINDING PROTEIN; PROTEIN CHP1; SINGLE STRANDED RNA; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING KINETICS; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DNA BINDING; GEL MOBILITY SHIFT ASSAY; GENE SILENCING; HETEROCHROMATIN; HISTONE METHYLATION; HYDROPHOBICITY; MOLECULAR RECOGNITION; MUTATIONAL ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN RNA BINDING; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; WILD TYPE;

AMINO ACID SEQUENCE; ARGONAUTE PROTEINS; CELL CYCLE PROTEINS; CHROMATIN IMMUNOPRECIPITATION; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; EUKARYOTIC INITIATION FACTORS; GENE EXPRESSION REGULATION, FUNGAL; GENE SILENCING; HETEROCHROMATIN; KINETICS; METHYLATION; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; RNA; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

SCHIZOSACCHAROMYCETACEAE;

EID: 84864297707     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2012.05.017     Document Type: Article

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