Selenoproteins reduce susceptibility to DMBA-induced mammary carcinogenesis

Carcinogenesis

Volumn 33, Issue 6, 2012, Pages 1225-1230

  Hudson, Tamaro S ^a,f   Carlson, Bradley A ^a   Hoeneroff, Mark J ^b   Young, Heather A ^c   Sordillo, Lorraine ^d   Muller, William J ^e   Hatfield, Dolph L ^a   Green, Jeffrey E ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c GEORGE WASHINGTON UNIVERSITY   (United States)

^d MICHIGAN STATE UNIVERSITY   (United States)

^e MCGILL UNIVERSITY   (Canada)

^f HOWARD UNIVERSITY CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7,12 DIMETHYLBENZYLBENZ[A]ANTRACENE; CARCINOGEN; DIMETHYLBENZ[A]ANTHRACENE; SELENOCYSTEINE; SELENOPROTEIN; TRANSFER RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; BREAST EPITHELIUM; CANCER GROWTH; CANCER INCIDENCE; CANCER PREVENTION; CANCER RISK; CANCER SUSCEPTIBILITY; CHEMICALLY INDUCED DISORDER; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE LOSS; GENE PRODUCT; GENETIC SUSCEPTIBILITY; GENOTYPE; HETEROZYGOTE; HOMOZYGOSITY; MOUSE; MOUSE MAMMARY TUMOR ONCOVIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSLATION; TISSUE SPECIFICITY;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; DISEASE PROGRESSION; FEMALE; GENOTYPE; MAMMARY NEOPLASMS, ANIMAL; MAMMARY TUMOR VIRUS, MOUSE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RNA, TRANSFER, AMINO ACID-SPECIFIC; SELENOCYSTEINE; SELENOPROTEINS;

EID: 84864294511     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgs129     Document Type: Article

References (49)

1. Hatfield, D.L. et al. (2011) Selenium: its molecular biology and role in human health. Springer, NYC.
2. Davis, C.D. et al. (2005) Are selenoproteins important for the cancer protective effects of selenium. Curr. Nutr. Food Sci., 1, 201-214.
3. Diwadkar-Navsariwala, V. et al. (2004) The link between selenium and chemoprevention: a case for selenoproteins. J. Nutr., 134, 2899-2902.
4. Ganther, H.E. (1999) Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase. Carcinogenesis, 20, 1657-1666.
5. Ip, C. (1998) Lessons from basic research in selenium and cancer prevention. J. Nutr., 128, 1845-1854.
6. Ip, C. et al. (2002) New concepts in selenium chemoprevention. Cancer Metastasis Rev., 21, 281-289.
7. Jung, H.J. et al. (2010) Current issues of selenium in cancer chemoprevention. Biofactors, 36, 153-158.
8. Lu, J. et al. (2005) Selenium and cancer chemoprevention: hypotheses integrating the actions of selenoproteins and selenium metabolites in epithelial and non-epithelial target cells. Antioxid. Redox Signal, 7, 1715-1727.
9. Medina, D. et al. (2001) Se-methylselenocysteine: a new compound for chemoprevention of breast cancer. Nutr. Cancer, 40, 12-17.
10. Rayman, M.P. (2005) Selenium in cancer prevention: a review of the evidence and mechanism of action. Proc. Nutr. Soc., 64, 527-542.
11. Rayman, M.P. (2009) Selenoproteins and human health: insights from epidemiological data. Biochim. Biophys. Acta., 1790, 1533-1540.
12. Zhuo, P. et al. (2009) Molecular mechanisms by which selenoproteins affect cancer risk and progression. Biochim. Biophys. Acta., 1790, 1546-1554.
13. Jackson, M.I. et al. (2008) Selenium and anticarcinogenesis: underlying mechanisms. Curr. Opin. Clin. Nutr. Metab. Care, 11, 718-726.
14. Brigelius-Flohe, R. (2008) Selenium compounds and selenoproteins in cancer. Chem. Biodivers., 5, 389-395.
15. Irons, R. et al. (2006) Both selenoproteins and low molecular weight selenocompounds reduce colon cancer risk in mice with genetically impaired selenoprotein expression. J. Nutr., 136, 1311-1317.
16. Diwadkar-Navsariwala, V. et al. (2006) Selenoprotein deficiency accelerates prostate carcinogenesis in a transgenic model. Proc. Natl. Acad. Sci. USA., 103, 8179-8184.
17. Hu, J. et al. (2010) GPX1 Pro198Leu polymorphism and breast cancer risk: a meta-analysis. Breast Cancer Res. Treat, 124, 425-431.
18. Hu, Y.J. et al. (2003) Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium. Cancer Res., 63, 3347-3351.
19. Maia, A.T. et al. (2009) Extent of differential allelic expression of candidate breast cancer genes is similar in blood and breast. Breast Cancer Res., 11, R88.
20. Birringer, M. et al. (2002) Trends in selenium biochemistry. Nat. Prod. Rep., 19, 693-718.
21. Hatfield, D.L. et al. (2002) How selenium has altered our understanding of the genetic code. Mol. Cell. Biol., 22, 3565-3576.
22. Stadtman, T.C. (2002) Discoveries of vitamin B12 and selenium enzymes. Annu. Rev. Biochem., 71, 1-16.
23. Xu, X.M. et al. (2007) New developments in selenium biochemistry: selenocysteine biosynthesis in eukaryotes and archaea. Biol. Trace Elem. Res., 119, 234-241.
24. Hatfield, D.L. et al. (2006) Selenocysteine incorporation machinery and the role of selenoproteins in development and health. Prog. Nucleic Acid Res. Mol. Biol., 81, 97-142.
25. Carlson, B.A. et al. (2009) Mouse models targeting selenocysteine tRNA expression for elucidating the role of selenoproteins in health and development. Molecules, 14, 3509-3527.
26. Kumaraswamy, E. et al. (2003) Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium. Mol. Cell. Biol., 23, 1477-1488.
27. Deng, C.X. et al. (2000) Roles of BRCA1 and its interacting proteins. Bioessays, 22, 728-737.
28. Evan, G. et al. (1998) Amatter of life and cell death. Science, 281, 1317-1322.
29. Venkitaraman, A.R. (2002) Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell, 108, 171-182.
30. Zhang, H. et al. (1998) BRCA1 physically associates with p.53 and stimulates its transcriptional activity. Oncogene, 16, 1713-1721.
31. Hennings, H. et al. (1993) FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin. Carcinogenesis, 14, 2353-2358.
32. Soriano, P. (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet., 21, 70-71.
33. Nicol, C.J. et al. (2004) PPARgamma influences susceptibility to DMBAinduced mammary, ovarian and skin carcinogenesis. Carcinogenesis, 25, 1747-1755.
34. Loonstra, A. et al. (2001) Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells. Proc. Natl. Acad. Sci. USA., 98, 9209-9214.
35. Hayashi, T. et al. (1993) Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin. J. Biol. Chem., 268, 11380-11388.
36. Hu, Y. et al. (2005) Allelic loss of the gene for the GPX1 selenium-containing protein is a common event in cancer. J. Nutr., 135, 3021S-3024S.
37. Hu, Y.J. et al. (2004) Allelic loss at the GPx-1 locus in cancer of the head and neck. Biol. Trace Elem. Res., 101, 97-106.
38. Bilodeau, J.F. et al. (2002) Glutathione peroxidase-1 expression enhances recovery of human breast carcinoma cells from hyperoxic cell cycle arrest. Free Radic. Biol. Med., 33, 1279-1289.
39. Kryukov, G.V. et al. (2003) Characterization of mammalian selenoproteomes. Science, 300, 1439-1443.
40. Reeves, M.A. et al. (2009) The human selenoproteome: recent insights into functions and regulation. Cell Mol. Life Sci., 66, 2457-2478.
41. Arner, E.S. (2009) Focus on mammalian thioredoxin reductases-important selenoproteins with versatile functions. Biochim. Biophys. Acta., 1790, 495-526.
42. Turanov, A.A. et al. (2010) Mammalian thioredoxin reductase 1: roles in redox homoeostasis and characterization of cellular targets. Biochem. J., 430, 285-293.
43. Franco, R. et al. (2009) Apoptosis and glutathione: beyond an antioxidant. Cell Death Differ, 16, 1303-1314.
44. Montero, A.J. et al. (2011) Cellular redox pathways as a therapeutic target in the treatment of cancer. Drugs, 71, 1385-1396.
45. Corti, A. et al. (2010) Gamma-glutamyltransferase of cancer cells at the crossroads of tumor progression, drug resistance and drug targeting. Anticancer Res., 30, 1169-1181.
46. Lei, X.G. et al. (2007) Metabolic regulation and function of glutathione peroxidase-1. Annu. Rev. Nutr., 27, 41-61.
47. Lubos, E. et al. (2011) Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities. Antioxid. Redox. Signal, 15, 1957-1997.
48. Lippman, S.M. et al. (2009) Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA, 301, 39-51.
49. Duffield-Lillico, A.J. et al. (2003) Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial. BJU Int., 91, 608-612.