Glutathione peroxidase-1 expression enhances recovery of human breast carcinoma cells from hyperoxic cell cycle arrest

Free Radical Biology and Medicine

Volumn 33, Issue 9, 2002, Pages 1279-1289

  Bilodeau, Jean François ^a,b   Patenaude, Alexandre ^a   Piedboeuf, Bruno ^a   Carrier, Caroline ^a   Petrov, Peter ^a   Faure, Robert ^a   Mirault, Marc Edouard ^a  

^a UNIVERSITÉ LAVAL   (Canada)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

Cdk2; Cell cycle; Free radicals; Glutathione peroxidase; Hyperoxia; Menadione; Mitochondria; Oxidative stress

Indexed keywords

FREE RADICAL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE PEROXIDASE 1; MENADIONE; PEROXIDE; REACTIVE OXYGEN METABOLITE; SCAVENGER; UNCLASSIFIED DRUG;

ARTICLE; BREAST CARCINOMA; CARCINOMA CELL; CELL CYCLE S PHASE; CELL GROWTH; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPEROXIA; LIPID PEROXIDATION; MITOCHONDRION; MITOSIS INHIBITION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BLOTTING, NORTHERN; BREAST NEOPLASMS; CDC2-CDC28 KINASES; CELL CYCLE; CELL DIVISION; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASES; FLOW CYTOMETRY; FREE RADICALS; GLUTATHIONE PEROXIDASE; HUMANS; HYPEROXIA; LIPID PEROXIDATION; MITOCHONDRIA; OXIDATIVE STRESS; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0036830150     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)01013-4     Document Type: Article

References (47)

1. Bilodeau J.F., Faure R., Piedboeuf B., Mirault M.E. Hyperoxia induces S phase cell-cycle arrest and p21(Cip1/Waf1)-independent Cdk2 inhibition in human carcinoma T47D-H3 cells. Exp. Cell Res. 256:2000;347-357.
2. Housset B., Hurbain I., Masliah J., Laghsal A., Chaumette-Demaugre M.T., Karam H., Derenne J. Toxic effects of oxygen on cultured alveolar epithelial cells, lung fibroblasts, and alveolar macrophages. Eur. Respir. J. 4:1991;1066-1075.
3. Kravetz G., Fisher A.B., Forman H.J. The oxygen-adapted rat model tolerance to oxygen at 1.5 and 2 ATA. Aviat. Space Environ. Med. 51:1980;775-777.
4. Forman H.J., Skelton D.C. Protection of alveolar macrophages from hyperoxia by γ-glutamyl transpeptidase. Am. J. Physiol. 259:1990;L102-L107.
5. 2. J. Appl. Physiol. 75:1993;1256-1262.
6. Ho Y.S., Magnenat J.L., Gargano M., Cao J. The nature of antioxidant defense mechanisms a lesson from transgenic studies. Environ. Health Perspect. 106:(Suppl. 5):1998;1219-1228.
7. Zweier J.L., Duke S.S., Kuppusamy P., Sylvester J.T., Gabrielson E.W. Electron paramagnetic resonance evidence that cellular oxygen toxicity is caused by the generation of superoxide and hydroxyl free radicals. FEBS Lett. 252:1989;12-16.
8. Guidot D.M., McCord J.M., Wright R.M., Repine J.E. Absence of electron transport (Rho 0 state) restores growth of a manganese-superoxide dismutase-deficient Saccharomyces cerevisiae in hyperoxia. Evidence for electron transport as a major source of superoxide generation in vivo. J. Biol. Chem. 268:1993;26699-26703.
9. Halliwell B., Gutteridge J.M.C. Role of free radicals and catalytic metal ions in human disease an overview. Methods Enzymol. 186:1990;1-85.
10. Suzuki Y.J., Forman H.J., Sevanian A. Oxidants as stimulators of signal transduction. Free Radic. Biol. Med. 22:1997;269-285.
11. Pahl H.L., Baeuerle P.A. Oxygen and the control of gene expression. Bioessays. 16:1994;497-502.
12. Janssen-Heininger Y.M., Poynter M.E., Baeuerle P.A. Recent advances towards understanding redox mechanisms in the activation of nuclear factor-κB. Free Radic. Biol. Med. 28:2000;1317-1327.
13. McGrath S.A. Induction of p21WAF/CIP1 during hyperoxia. Am. J. Respir. Cell Mol. Biol. 18:1998;179-187.
14. O'Reilly M.A., Staversky R.J., Stripp B.R., Finkelstein J.N. Exposure to hyperoxia induces p53 expression in mouse lung epithelium. Am. J. Respir. Cell Mol. Biol. 18:1998;43-50.
15. Corroyer S., Maitre B., Cazals V., Clement A. Altered regulation of G1 cyclins in oxidant-induced growth arrest of lung alveolar epithelial cells. Accumulation of inactive cyclin E-DCK2 complexes. J. Biol. Chem. 271:1996;25117-25125.
16. White C.W., Avraham K.B., Shanley P.F., Groner Y. Transgenic mice with expression of elevated levels of copper-zinc superoxide dismutase in the lungs are resistant to pulmonary oxygen toxicity. J. Clin. Invest. 87:1991;2162-2168.
17. White C.W., Nguyen D.H., Suzuki K., Taniguchi N., Rusakow L.S., Avraham K.B., Groner Y. Expression of manganese superoxide dismutase is not altered in transgenic mice with elevated level of copper-zinc superoxide dismutase. Free Radic. Biol. Med. 15:1993;629-636.
18. Ho Y.S., Gargano M., Cao J., Bronson R.T., Heimler I., Hutz R.J. Reduced fertility in female mice lacking copper-zinc superoxide dismutase. J. Biol. Chem. 273:1998;7765-7769.
19. Ho Y.S., Vincent R., Dey M.S., Slot J.W., Crapo J.D. Transgenic models for the study of lung antioxidant defense enhanced manganese-containing superoxide dismutase activity gives partial protection to B6C3 hybrid mice exposed to hyperoxia. Am. J. Respir. Cell Mol. Biol. 18:1998;538-547.
20. Jackson R.M., Helton E.S., Viera L., Ohman T. Survival, lung injury, and lung protein nitration in heterozygous MnSOD knockout mice in hyperoxia. Exp. Lung Res. 25:1999;631-646.
21. Forman H.J., Rotman E.I., Fisher A.B. Roles of selenium and sulfur-containing amino acids in protection against oxygen toxicity. Lab. Invest. 49:1983;148-153.
22. Ho Y.S., Magnenat J.L., Bronson R.T., Cao J., Gargano M., Sugawara M., Funk C.D. Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia. J. Biol. Chem. 272:1997;16644-16651.
23. de Haan J.B., Bladier C., Griffiths P., Kelner M., O'Shea R.D., Cheung N.S., Bronson R.T., Silvestro M.J., Wild S., Zheng S.S., Beart P.M., Hertzog P.J., Kola I. Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide. J. Biol. Chem. 273:1998;22528-22536.
24. Mirault M.-E., Tremblay A., Beaudouin N., Tremblay M. Overexpression of seleno-glutathione peroxidase by gene transfer enhances the resistance of T47D human breast cells to clastogenic oxidants. J. Biol. Chem. 266:1991;20752-20760.
25. Mirault M.-E., Tremblay A., Lavoie L., Tremblay M., Beaudoin N. Transgenic expression of glutathione peroxidase in human breast cells increased resistance to clastogenic oxidants. Jesaitis A.J., Dratz E.A., The molecular basis of oxidative damage by leukocytes. 1992;303-306 CRC Press Inc, Boca Raton, FL.
26. Doroshow J.H. Glutathione peroxidase and oxidative stress. Toxicol. Lett. 82-83:1995;395-398.
27. Kelner M.J., Bagnell R.D., Uglik S.F., Montoya M.A., Mullenbach G.T. Heterologous expression of selenium-dependent glutathione peroxidase affords cellular resistance to paraquat. Arch. Biochem. Biophys. 323:1995;40-46.
28. Michiels C., Raes M., Toussaint O., Remacle J. Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress. Free Radic. Biol. Med. 17:1994;235-248.
29. Michiels C., Raes M., Zachary M.D., Delaive E., Remacle J. Microinjection of antibodies against superoxide dismutase and glutathione peroxidase. Exp. Cell Res. 179:1988;581-589.
30. Kong X.J., Lee S.L., Lanzillo J.J., Fanburg B.L. Cu,Zn superoxide dismutase in vascular cells changes during cell cycling and exposure to hyperoxia. Am. J. Physiol. 264:1993;L365-L375.
31. Legault J., Carrier C., Petrov P., Renard P., Remacle J., Mirault M.E. Mitochondrial GPx1 decreases induced but not basal oxidative damage to mtDNA in T47D cells. Biochem. Biophys. Res. Commun. 272:2000;416-422.
32. Ormerod M.G., Kubbies M. Cell cycle analysis of asynchronous cell populations by flow cytometry using bromodeoxyuridine label and Hoechst-propidium iodide stain. Cytometry. 13:1992;678-685.
33. Rothe G., Valet G. Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′,7′-dichlorofluorescin. J. Leukocyte Biol. 47:1990;440-448.
34. Zamzami N., Marchetti P., Castedo M., Decaudin D., Macho A., Hirsch T., Susin S.A., Petit P.X., Mignotte B., Kroemer G. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J. Exp. Med. 182:1995;367-377.
35. Piedboeuf B., Johnston C.J., Watkins R.H., Hudak B.B., Lazo J.S., Cherian M.G., Horowitz S. Increased expression of tissue inhibitor of metalloproteinases (TIMP-I) and metallothionein in murine lungs after hyperoxic exposure. Am. J. Respir. Cell Mol. Biol. 10:1994;123-132.
36. Tyrrell R.M., Basu-Modak S. Transient enhancement of heme oxygenase-1 mRNA accumulation a marker of oxidative stress to eukaryotic cells. Methods Enzymol. 234:1994;224-235.
37. Clements J.A., Matheson B.A., Wines D.R., Brady J.M., MacDonald R.J., Funder J.W. Androgen dependence of specific kallikrein gene family members expressed in rat prostate. J. Biol. Chem. 263:1988;16132-16137.
38. Tsan M.F. Superoxide dismutase and pulmonary oxygen toxicity lessons from transgenic and knockout mice. (review). Int. J. Mol. Med. 7:2001;13-19.
39. Lindau-Shepard B., Shaffer J.B., Del Vecchio P.J. Overexpression of manganous superoxide dismutase (MnSOD) in pulmonary endothelial cells confers resistance to hyperoxia. J. Cell Physiol. 161:1994;237-242.
40. Frank L., Massaro D. Oxygen toxicity. Am. J. Med. 69:1980;117-126.
41. Frank L., Bucher J.R., Roberts R.J. Oxygen toxicity in neonatal and adult animals of various species. J. Appl. Physiol. 45:1978;699-704.
42. Frank L. Effects of oxygen on the newborn. Fed. Proc. 44:1985;2328-2334.
43. Pervin S., Singh R., Chaudhuri G. Nitric oxide-induced cytostasis and cell cycle arrest of a human breast cancer cell line (MDA-MB-231) potential role of cyclin D1. Proc. Natl. Acad. Sci. USA. 98:2001;3583-3588.
44. Ishida A., Sasaguri T., Kosaka C., Nojima H., Ogata J. Induction of the cyclin-dependent kinase inhibitor p21(Sdi1/Cip1/Waf1) by nitric oxide-generating vasodilator in vascular smooth muscle cells. J. Biol. Chem. 272:1997;10050-10057.
45. Guo K., Andres V., Walsh K. Nitric oxide-induced downregulation of Cdk2 activity and cyclin A gene transcription in vascular smooth muscle cells. Circulation. 97:1998;2066-2072.
46. Esposito L.A., Kokoszka J.E., Waymire K.G., Cottrell B., MacGregor G.R., Wallace D.C. Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene. Free Radic. Biol. Med. 28:2000;754-766.
47. Bilodeau, J. F. Ph. D. Thesis. Étude des effets de l'hyperoxie sur le cycle cellulaire dans des cellules surexprimant la glutathion peroxydase. Molecular and Cellular Biology. Québec City, Université Laval, 1998.