Induction and activation of antiviral enzyme 2′,5′- oligoadenylate synthetase by in vitro transcribed insulin mRNA and other cellular RNAs

Molecular Biology Reports

Volumn 39, Issue 7, 2012, Pages 7813-7822

  Dan, Meixia ^a   Zheng, Dongjun ^a   Field, L Leigh ^a   Bonnevie Nielsen, Vagn ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

2 ,5 Oligoadenylate synthetase; Double stranded RNA; INS VNTR; Pancreatic beta cell

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; DOUBLE STRANDED RNA; INSULIN; MESSENGER RNA; RETINOIC ACID INDUCIBLE PROTEIN I;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; GENE; GENE ACTIVATION; GENE SEQUENCE; GENETIC PREDISPOSITION; GENETIC TRANSCRIPTION; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MOUSE; NONHUMAN; OAS GENE; PANCREAS ISLET BETA CELL; PROMOTER REGION; PROTEIN EXPRESSION;

2',5'-OLIGOADENYLATE SYNTHETASE; ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DEAD-BOX RNA HELICASES; DIABETES MELLITUS, TYPE 1; GENETIC PREDISPOSITION TO DISEASE; HEK293 CELLS; HELA CELLS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MINISATELLITE REPEATS; PROMOTER REGIONS, GENETIC; RNA, DOUBLE-STRANDED; RNA, MESSENGER; TOLL-LIKE RECEPTOR 7;

MURINAE;

EID: 84864287245     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-1624-x     Document Type: Article

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