Impedance pH confirms the relationship between GERD and BMI

Digestive Diseases and Sciences

Volumn 57, Issue 7, 2012, Pages 1875-1879

  Hajar, Nasser ^a   Castell, Donald O ^b   Ghomrawi, Hassan ^c   Rackett, Richard ^d   Hila, Amine ^d  

^a SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c Department of Obstetrics Gynecology   (United States)

^d Binghamton Gastroenterology   (United States)

Author keywords

Body mass index; Esophageal motility; GERD; MII pH; Obesity; Reflux during recumbency; Symptom index

Indexed keywords

PROTON PUMP INHIBITOR;

ACID REFLUX; ADULT; AGED; BODY MASS; CONTROLLED STUDY; GASTROESOPHAGEAL REFLUX; HUMAN; MAJOR CLINICAL STUDY; NONACID REFLUX; OBESITY; PH MEASUREMENT; PRIORITY JOURNAL; REVIEW;

ADOLESCENT; ADULT; AGED; BODY MASS INDEX; ELECTRIC IMPEDANCE; ESOPHAGEAL PH MONITORING; FEMALE; GASTROESOPHAGEAL REFLUX; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MIDDLE AGED; OBESITY; OVERWEIGHT; PREVALENCE; PROTON PUMP INHIBITORS; RETROSPECTIVE STUDIES; RISK FACTORS; YOUNG ADULT;

EID: 84864284274     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-012-2131-6     Document Type: Review

References (21)

1. Mokdad AH, Serdula MK, Dietz WH, et al. The spread of the obesity epidemic in the United States, 1991-1998. JAMA. 1999; 282:1519-1522. (Pubitemid 29504044)
2. Flegal KM, Carroll MD, Ogden CL, et al. Prevalence and trends in obesity among US adults, 1999-2000. JAMA. 2002;288: 1723-1727.
3. Ogden CL, Carroll MD, McDowell, et al. Obesity among adults in the United States - no statistically significant change since 2003-2004. NCHS Data Brief. 2007;1:1-8.
4. Blumberg SJ, Luke JV, Davidson G, et al. Wireless substitution: state-level estimates from the National Health Interview Survey, January-December 2007. Natl Health Stat Report. 2009;11:16.
5. El-Serag HB, Petersen NJ, Carter J, et al. Gastroesophageal reflux among different racial groups in the United States. Gastroenterology. 2004;126:1692-1699. (Pubitemid 38736334)
6. Lambert R. In search of reliability in the description of gastroesophageal reflux disease (GERD). Esophagus. 2008;5:5-9. (Pubitemid 351501742)
7. El Serag HB. The association between obesity and GERD: a review of the epidemiological evidence. Dig Dis Sci. 2008;53: 2307-2312.
8. Crowell MD, Bradley A, Hansel S, et al. Obesity is associated with increased 48-h esophageal acid exposure in patients with symptomatic gastroesophageal reflux. Am J Gastroenterol. 2009; 104:553-559.
9. Ayazi S, Hagen JA, Chan LS, et al. Obesity and gastroesophageal reflux: quantifying the association between body mass index, esophageal acid exposure, and lower esophageal sphincter status in a large series of patients with reflux symptoms. J Gastrointest Surg. 2009;13:1440-1447.
10. Sifrim D, Castell D, Dent J, et al. Gastro-oesophageal reflux monitoring: review and consensus report on detection and definitions of acid, non-acid, and gas reflux. Gut. 2004;53:1024-1031. (Pubitemid 38824163)
11. Hirano I, Richter JE, et al. ACG practice guidelines: esophageal reflux testing. Am J Gastroenterol. 2007;102:668-685. (Pubitemid 46328165)
12. National Institutes of Health. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults - the evidence report. Obes Res. 1998;6:51S-209S.
13. Wiener GJ, Richter JE, Copper JB, et al. The symptom index: a clinically important parameter of ambulatory 24-hour esophageal pH monitoring. Am J Gastroenterol. 1988;83:358-361.
14. Singh S, Richter JE, Bradley LA, et al. The symptom index. Differential usefulness in suspected acid-related complaints of heartburn and chest pain. Dig Dis Sci. 1993;38:1402-1408. (Pubitemid 23266617)
15. Mainie I, Tutuian R, Shay S, et al. Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicenter study using combined ambulatory impedance-pH monitoring. Gut. 2006;55:1398-1402. (Pubitemid 44476780)
16. Kuo B, Castell DO. Optimal dosing of omeprazole 40 mg daily: effects on gastric and esophageal pH and serum gastrin in healthy controls. Am J Gastroenterol. 1996;91:1532-1538. (Pubitemid 26269165)
17. World Health Organization. Obesity: preventing and managing the global epidemic. Report of a WHO convention, Geneva, 1999. World Health Organ Tech Rep Ser. 2000;894:1-253.
18. Connor J, Richter J. Increasing yield also increases false positives and best serves to exclude GERD. Am J Gastroenterol. 2006; 101:460-463. (Pubitemid 43340919)
19. Pandolfino J. The relationship between obesity and GERD: "big or overblown". Am J Gastroenterol. 2008;103:1355-1357. (Pubitemid 351813942)
20. Wu JC, Mui LM, Cheung CM, et al. Obesity is associated with increased transient lower esophageal sphincter relaxation. Gastroenterology. 2007;132:883-889. (Pubitemid 46440865)
21. Pandolfino JE, El Serag HB, Zhang Q, et al. Obesity: a challenge to esophagogastric junction integrity. Gastroenterology. 2006;130: 639-649. (Pubitemid 43374513)