메뉴 건너뛰기




Volumn 38, Issue 8, 2012, Pages 1326-1335

Persistent hypocoagulability in patients with septic shock predicts greater hospital mortality: Impact of impaired thrombin generation

Author keywords

Anticoagulants; Blood coagulation disorders; Disseminated intravascular coagulation; Septic shock; Thrombin; Thromboelastography

Indexed keywords

ADULT; AGED; ARTICLE; BLOOD CLOTTING TEST; DISEASE SEVERITY; DISSEMINATED INTRAVASCULAR CLOTTING; FEMALE; HOSPITAL ADMISSION; HUMAN; HYPOCOAGULABILITY; INTENSIVE CARE UNIT; MALE; MORTALITY; PARTIAL THROMBOPLASTIN TIME; SEPTIC SHOCK; THROMBIN TIME;

EID: 84864283806     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-012-2620-2     Document Type: Article
Times cited : (54)

References (42)
  • 3
  • 4
    • 0032446765 scopus 로고    scopus 로고
    • Activation of the extrinsic coagulation pathway in patients with severe sepsis and septic shock
    • DOI 10.1097/00003246-199812000-00030
    • Gando S, Nanzaki S, Sasaki S, Aoi K, Kemmotsu O (1998) Activation of the extrinsic coagulation pathway in patients with severe sepsis and septic shock. Crit Care Med 26:2005-2009 (Pubitemid 29016682)
    • (1998) Critical Care Medicine , vol.26 , Issue.12 , pp. 2005-2009
    • Gando, S.1    Nanzaki, S.2    Sasaki, S.3    Aoi, K.4    Kemmotsu, O.5
  • 6
    • 34250736946 scopus 로고    scopus 로고
    • Fibrin and fibrinolysis in infection and host defense
    • DOI 10.1111/j.1538-7836.2007.02519.x, State of the Art 2007: XXI Congress of the International Society on Thrombosis and Haemostasis
    • Degen JL, Bugge TH, Goguen JD (2007) Fibrin and fibrinolysis in infection and host defense. J Thromb Haemost 5(Suppl 1):24-31 (Pubitemid 46958813)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.SUPPL. 1 , pp. 24-31
    • Degen, J.L.1    Bugge, T.H.2    Goguen, J.D.3
  • 17
    • 0033576811 scopus 로고    scopus 로고
    • Disseminated intravascular coagulation
    • DOI 10.1056/NEJM199908193410807
    • Levi M, Ten Cate H (1999) Disseminated intravascular coagulation. N Engl J Med 341:586-592 (Pubitemid 29384168)
    • (1999) New England Journal of Medicine , vol.341 , Issue.8 , pp. 586-592
    • Levi, M.1    Ten Cate, H.2
  • 18
    • 4444233598 scopus 로고    scopus 로고
    • Persistent-microcirculatory alterations are associated with organ failure and death in patients with septic shock
    • DOI 10.1097/01.CCM.0000138558.16257.3F
    • Sakr Y, Dubois MJ, De Backer D, Creteur J, Vincent JL (2004) Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med 32:1825-1831 (Pubitemid 39202356)
    • (2004) Critical Care Medicine , vol.32 , Issue.9 , pp. 1825-1831
    • Sakr, Y.1    Dubois, M.-J.2    De Backer, D.3    Creteur, J.4    Vincent, J.-L.5
  • 20
    • 33751210094 scopus 로고    scopus 로고
    • Thrombin generation, a function test of the haemostatic-thrombotic system
    • DOI 10.1160/TH06-07-0408
    • Hemker HC, Al Dieri R, De Smedt E, Beguin S (2006) Thrombin generation, a function test of the haemostatic-thrombotic system. Thromb Haemost 96:553-561 (Pubitemid 44782533)
    • (2006) Thrombosis and Haemostasis , vol.96 , Issue.5 , pp. 553-561
    • Hemker, H.C.1    Al Dieri, R.2    De Smedt, E.3    Beguin, S.4
  • 21
    • 50049135947 scopus 로고    scopus 로고
    • Thrombin generation testing in routine clinical practice: Are we there yet?
    • van Veen JJ, Gatt A, Makris M (2008) Thrombin generation testing in routine clinical practice: are we there yet? Br J Haematol 142:889-903
    • (2008) Br J Haematol , vol.142 , pp. 889-903
    • Van Veen, J.J.1    Gatt, A.2    Makris, M.3
  • 22
    • 17144365499 scopus 로고    scopus 로고
    • Thrombelastography/thromboelastometry
    • DOI 10.1111/j.1365-2257.2005.00681.x
    • Luddington RJ (2005) Thrombelastography/thromboelastometry. Clin Lab Haematol 27:81-90 (Pubitemid 40515992)
    • (2005) Clinical and Laboratory Haematology , vol.27 , Issue.2 , pp. 81-90
    • Luddington, R.J.1
  • 23
    • 78650492660 scopus 로고    scopus 로고
    • Prospective assessment of thrombin generation test for dose monitoring of bypassing therapy in hemophilia patients with inhibitors undergoing elective surgery
    • Dargaud Y, Lienhart A, Negrier C (2010) Prospective assessment of thrombin generation test for dose monitoring of bypassing therapy in hemophilia patients with inhibitors undergoing elective surgery. Blood 116:5734-5737
    • (2010) Blood , vol.116 , pp. 5734-5737
    • Dargaud, Y.1    Lienhart, A.2    Negrier, C.3
  • 24
    • 47649111844 scopus 로고    scopus 로고
    • High thrombin generation measured in the presence of thrombomodulin is associated with an increased risk of recurrent venous thromboembolism
    • DOI 10.1111/j.1538-7836.2008.03018.x
    • Tripodi A, Legnani C, Chantarangkul V, Cosmi B, Palareti G, Mannucci PM (2008) High thrombin generation measured in the presence of thrombomodulin is associated with an increased risk of recurrent venous thromboembolism. J Thromb Haemost 6:1327-1333 (Pubitemid 352016312)
    • (2008) Journal of Thrombosis and Haemostasis , vol.6 , Issue.8 , pp. 1327-1333
    • Tripodi, A.1    Legnani, C.2    Chantarangkul, V.3    Cosmi, B.4    Palareti, G.5    Mannucci, P.M.6
  • 28
    • 34248374189 scopus 로고    scopus 로고
    • Four-day antithrombin therapy does not seem to attenuate hypercoagulability in patients suffering from sepsis
    • Gonano C, Sitzwohl C, Meitner E, Weinstabl C, Kettner SC (2006) Four-day antithrombin therapy does not seem to attenuate hypercoagulability in patients suffering from sepsis. Crit Care 10:R160
    • (2006) Crit Care , vol.10
    • Gonano, C.1    Sitzwohl, C.2    Meitner, E.3    Weinstabl, C.4    Kettner, S.C.5
  • 29
    • 65249181474 scopus 로고    scopus 로고
    • Thromboelastometry for the assessment of coagulation abnormalities in early and established adult sepsis: A prospective cohort study
    • Daudel F, Kessler U, Folly H, Lienert JS, Takala J, Jakob SM (2009) Thromboelastometry for the assessment of coagulation abnormalities in early and established adult sepsis: a prospective cohort study. Crit Care 13:R42
    • (2009) Crit Care , vol.13
    • Daudel, F.1    Kessler, U.2    Folly, H.3    Lienert, J.S.4    Takala, J.5    Jakob, S.M.6
  • 31
    • 79961061391 scopus 로고    scopus 로고
    • Comparison of thrombelastometry with simplified acute physiology score II and sequential organ failure assessment scores for the prediction of 30-day survival: A cohort study
    • Adamzik M, Langemeier T, Frey UH, Gorlinger K, Saner F, Eggebrecht H, Peters J, Hartmann M (2011) Comparison of thrombelastometry with simplified acute physiology score II and sequential organ failure assessment scores for the prediction of 30-day survival: a cohort study. Shock 35:339-342
    • (2011) Shock , vol.35 , pp. 339-342
    • Adamzik, M.1    Langemeier, T.2    Frey, U.H.3    Gorlinger, K.4    Saner, F.5    Eggebrecht, H.6    Peters, J.7    Hartmann, M.8
  • 34
    • 1342268344 scopus 로고    scopus 로고
    • Citrate vs. heparin for anticoagulation in continuous venovenous hemofiltration: A prospective randomized study
    • DOI 10.1007/s00134-003-2047-x
    • Monchi M, Berghmans D, Ledoux D, Canivet JL, Dubois B, Damas P (2004) Citrate vs. heparin for anticoagulation in continuous venovenous hemofiltration: a prospective randomized study. Intensive Care Med 30:260-265 (Pubitemid 38253417)
    • (2004) Intensive Care Medicine , vol.30 , Issue.2 , pp. 260-265
    • Monchi, M.1    Berghmans, D.2    Ledoux, D.3    Canivet, J.-L.4    Dubois, B.5    Damas, P.6
  • 35
    • 31344446122 scopus 로고    scopus 로고
    • New disseminated intravascular coagulation score: A useful tool to predict mortality in comparison with acute physiology and chronic health evaluation II and logistic organ dysfunction scores
    • quiz 328
    • Angstwurm MW, Dempfle CE, Spannagl M (2006) New disseminated intravascular coagulation score: a useful tool to predict mortality in comparison with Acute Physiology and Chronic Health Evaluation II and Logistic Organ Dysfunction scores. Crit Care Med 34:314-320 (quiz 328)
    • (2006) Crit Care Med , vol.34 , pp. 314-320
    • Angstwurm, M.W.1    Dempfle, C.E.2    Spannagl, M.3
  • 37
    • 34548696635 scopus 로고    scopus 로고
    • Thrombin generation in plasma of healthy adults and children: Chromogenic versus fluorogenic thrombogram analysis
    • DOI 10.1160/TH07-03-0210
    • Devreese K, Wijns W, Combes I, Van kerckhoven S, Hoylaerts MF (2007) Thrombin generation in plasma of healthy adults and children: chromogenic versus fluorogenic thrombogram analysis. Thromb Haemost 98:600-613 (Pubitemid 47412886)
    • (2007) Thrombosis and Haemostasis , vol.98 , Issue.3 , pp. 600-613
    • Devreese, K.1    Wijns, W.2    Combes, I.3    Van Kerckhoven, S.4    Hoylaerts, M.F.5
  • 39
    • 8544284118 scopus 로고    scopus 로고
    • Hospital mortality and resource use in subgroups of the recombinant human activated protein C worldwide evaluation in severe sepsis (PROWESS) trial
    • DOI 10.1097/01.CCM.0000145231.71605.D8
    • Laterre PF, Levy H, Clermont G, Ball DE, Garg R, Nelson DR, Dhainaut JF, Angus DC (2004) Hospital mortality and resource use in subgroups of the recombinant human activated protein C worldwide evaluation in severe sepsis (PROWESS) trial. Crit Care Med 32:2207-2218 (Pubitemid 39491799)
    • (2004) Critical Care Medicine , vol.32 , Issue.11 , pp. 2207-2218
    • Laterre, P.-F.1    Levy, H.2    Clermont, G.3    Ball, D.E.4    Garg, R.5    Nelson, D.R.6    Dhainaut, J.-F.7    Angus, D.C.8
  • 42
    • 0026534242 scopus 로고
    • Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficiencies
    • Fourrier F, Chopin C, Goudemand J, Hendrycx S, Caron C, Rime A, Marey A, Lestavel P (1992) Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficiencies. Chest 101:816-823
    • (1992) Chest , vol.101 , pp. 816-823
    • Fourrier, F.1    Chopin, C.2    Goudemand, J.3    Hendrycx, S.4    Caron, C.5    Rime, A.6    Marey, A.7    Lestavel, P.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.