Thrombin generation in plasma of healthy adults and children: Chromogenic versus fluorogenic thrombogram analysis

Thrombosis and Haemostasis

Volumn 98, Issue 3, 2007, Pages 600-613

  Devreese, Katrien ^a   Wijns, Walter ^b   Combes, Isabelle ^a   Van Kerckhoven, Soetkin ^c   Hoylaerts, Marc F ^c  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b ERASME HOSPITAL   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Coagulation assays; Endogenous thrombin potential; Fibrinogen; Tissue factor

Indexed keywords

BLOOD CLOTTING FACTOR 8 ANTIBODY; CHROMOGENIC SUBSTRATE; RECOMBINANT THROMBOPLASTIN; THROMBIN;

ACCURACY; ADULT; AGE DISTRIBUTION; ARTICLE; AUTOMATION; BLOOD CLOTTING; BLOOD SAMPLING; CHILD; CONTROLLED STUDY; CORRELATION ANALYSIS; GENDER; HUMAN; INTERMETHOD COMPARISON; NORMAL HUMAN; PRIORITY JOURNAL; REFERENCE VALUE; SENSITIVITY ANALYSIS; THROMBIN TIME; THROMBOGRAM;

ADOLESCENT; ADULT; AGE FACTORS; ANTIBODIES; BLOOD COAGULATION; BLOOD COAGULATION TESTS; CALIBRATION; CHILD; CHILD, PRESCHOOL; CHROMOGENIC COMPOUNDS; COUMARINS; EQUIPMENT DESIGN; FACTOR VIII; FEMALE; FLUORESCENT DYES; HUMANS; INFANT; MALE; MIDDLE AGED; OBSERVER VARIATION; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; SEX FACTORS; THROMBIN; THROMBOPLASTIN; TIME FACTORS;

EID: 34548696635     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH07-03-0210     Document Type: Article

References (19)

1. Baglin T. The measurement and application of thrombin generation. Br J Haematol 2005; 130: 653-661.
2. Hemker HC, Béguin S. Phenotyping the clotting system. Thromb Haemost 2000; 84: 747-751.
3. Brummel-Ziedins KE, Pouliot RL, Mann KG. Thrombin generation: phenotypic quantitation. J Thromb Haemost 2003; 2: 281-288.
4. Hemker HC, Dieri RA, De Smedt E, et al. Thrombin generation, a function test of the haemostaticthrombotic system. Thromb Haemost 2006; 96: 553-561.
5. Biggs R, Macfarlane RG. Human blood coagulation and its disorders. Oxford Blackwell, 1953.
6. Macfarlane RG, Biggs R. A thrombin generation test. J Clin Pathol 1953; 6: 3-7.
7. Hemker HC, Willems GM, Béguin S. A computer assisted method to obtain the prothrombin activation velocity in whole plasma in whole plasma independent of thrombin decay processes. Thromb Haemost 1986; 56: 9-17.
8. Hemker HC, Wielders S, Kessels H, et al. Continuous registration of thrombin generation in plasma, its use for the determination of the thrombin potential. Thromb Haemost 1993; 71: 617-624.
9. Hemker HC, Giesen P, Al Dieri R, et al. Calibrated automated thrombin generation measurement in clotting plasma. Pathophysiol Haemost Thromb 2003; 33: 4-15.
10. Jacquemin MG, Desqueper BG, Benhida A, et al. Mechanism and kinetics of factor VIII inactivation: study with an IgG4 monoclonal antibody derived from a hemophilia A patient with inhibitor. Blood 1998; 92: 496-506.
11. Josso F, Prou-Wartelle O. Interaction of tissue factor and factor VII at the earliest phase of coagulation. Thromb Diath Haemorrh 1965; 17: 35-44.
12. Luddington R, Baglin T. Clinical measurement of thrombin generation by calibrated automated thrombography requires contact factor inhibition. J Thromb Haemost 2004; 2: 1954-1959.
13. Baglin T. The measurement and application of thrombin generation. Br J Haematol 2005; 130: 653-661.
14. Mannhalter C, Quehenberger P. Laboratory methods in the haemostatic laboratory. Thromb Haemost 2006; 96: 545-546.
15. Gerotziafas GT, Depasse F, Busson J, et al. Towards a standardization of thrombin generation assessment: The influence of tissue factor, platelets and phospholipids concentration on the normal values of Thrombogram-Thrombinoscope assay. Thromb J 2005; 3: 16.
16. Al Dieri R, Alban S, Béguin S, et al. Thrombin generation for the control of heparin treatment, comparison with the activated thromboplastin time. J Thromb Haemost 2004; 2: 1003-1007.
17. Lawrie AS, Gray E, Leeming D, et al. A multicentre assessment of the endogenous thrombin potential using a continuous monitoring amidolytic technique. Br J Haematol 2003; 123: 335-341.
18. Haidl H, Cimenti C, Leschnik B, et al. Age-dependency of thrombin generation measured by means of calibrated automated thrombography (CAT). Thromb Haemost 2006; 95: 772-775.
19. Andrew M, Vegh P, Johnston M, et al. Maturation of the hemostatic system during childhood. Blood 1992; 80: 1998-2005.