Reduced interferon (IFN)-α conditioned by IFNA2 (-173) and IFNA8 (-884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality

Human Genetics

Volumn 131, Issue 8, 2012, Pages 1375-1391

  Kempaiah, Prakasha ^a   Anyona, Samuel B ^b   Raballah, Evans ^b   Davenport, Gregory C ^a   Were, Tom ^b,c   Hittner, James B ^b,d   Ong'Echa, John M ^a   Perkins, Douglas J ^a,b  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

^c KENYATTA UNIVERSITY   (Kenya)

^d School of Business and Economics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; LUCIFERASE;

ALLELE; ANEMIA; ARTICLE; CHILD; CONTROLLED STUDY; CYTOKINE PRODUCTION; ERYTHROPOIESIS; FEMALE; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENETIC POLYMORPHISM; GENETIC RISK; HAPLOTYPE; HETEROZYGOSITY; HETEROZYGOTE; HUMAN; INFANT; INFECTION SENSITIVITY; INFLAMMATION; KENYA; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALARIA; MALE; MORTALITY; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROMOTER REGION; SEVERE MALARIAL ANEMIA; WILD TYPE;

PLASMODIUM FALCIPARUM;

EID: 84864280498     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-012-1175-1     Document Type: Article

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