Aggressive cardiovascular phenotype of aneurysms-osteoarthritis syndrome caused by pathogenic SMAD3 variants

Journal of the American College of Cardiology

Volumn 60, Issue 5, 2012, Pages 397-403

  Van Der Linde, Denise ^a   Van De Laar, Ingrid M B H ^a   Bertoli Avella, Aida M ^a   Oldenburg, Rogier A ^a   Bekkers, Jos A ^a   Mattace Raso, Francesco U S ^a   Van Den Meiracker, Anton H ^a   Moelker, Adriaan ^a   Van Kooten, Fop ^a   Frohn Mulder, Ingrid M E ^a   Timmermans, Janneke ^b   Moltzer, Els ^a   Cobben, Jan M ^c   Van Laer, Lut ^d   Loeys, Bart ^d   De Backer, Julie ^e   Coucke, Paul J ^e   De Paepe, Anne ^e   Hilhorst Hofstee, Yvonne ^f   Wessels, Marja W ^a   Roos Hesselink, Jolien W ^a   more..

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^e GHENT UNIVERSITY HOSPITAL   (Belgium)

^f LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

aneurysm; aorta; cerebrovascular disorders; genetics; SMAD3

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE;

ABDOMINAL AORTA ANEURYSM; ADULT; ANEURYSM; ANEURYSM OSTEOARTHRITIS SYNDROME; AORTA; AORTA ANEURYSM; AORTA DISSECTION; AORTA ROOT; ARTERIAL STIFFNESS; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CARDIOVASCULAR SYMPTOM; CARDIOVASCULAR SYSTEM EXAMINATION; CAUSE OF DEATH; CEREBROVASCULAR DISEASE; CHEMICAL ANALYSIS; CLINICAL ARTICLE; COHORT ANALYSIS; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DIAGNOSTIC IMAGING; FEMALE; GENE; GENETIC VARIABILITY; HEART ATRIUM FIBRILLATION; HEART LEFT VENTRICLE HYPERTROPHY; HUMAN; MALE; MITRAL VALVE DISEASE; NEUROIMAGING; OSTEOARTHRITIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PULSE WAVE; SMAD3 GENE;

ADOLESCENT; ADULT; AGED; ANEURYSM; ANEURYSM, DISSECTING; AORTIC ANEURYSM, THORACIC; AORTOGRAPHY; CARDIOVASCULAR DISEASES; CAUSE OF DEATH; CEREBROVASCULAR DISORDERS; CHROMOSOME ABERRATIONS; COHORT STUDIES; FEMALE; GENES, DOMINANT; GENOMIC STRUCTURAL VARIATION; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MALE; MIDDLE AGED; NATRIURETIC PEPTIDE, BRAIN; OSTEOARTHRITIS; PEPTIDE FRAGMENTS; PHENOTYPE; PREGNANCY; SMAD3 PROTEIN; SURVIVAL ANALYSIS; SYNDROME; VASCULAR STIFFNESS; YOUNG ADULT;

EID: 84864277231     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2011.12.052     Document Type: Article

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