Absence of PTHrP nuclear localization and carboxyl terminus sequences leads to abnormal brain development and function

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Gu, Zhen ^a   Liu, Yahong ^a   Zhang, Yongjie ^a   Jin, Shulei ^a   Chen, Qi ^a   Goltzman, David ^b   Karaplis, Andrew ^b   Miao, Dengshun ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PARATHYROID HORMONE RELATED PROTEIN; PROTEIN P16; PROTEIN P21; PROTEIN P27; PROTEIN P53;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; BRAIN ELECTROPHYSIOLOGY; BRAIN FUNCTION; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; CELL SHAPE; CELL STRUCTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DOWN REGULATION; HIPPOCAMPUS; HISTOLOGY; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MORPHOMETRICS; MOUSE; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NEURAL STEM CELL; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; ONCOGENE; ONCOGENE BMI 1; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SYNAPTIC TRANSMISSION; UPREGULATION; WESTERN BLOTTING; WILD TYPE;

ANIMALS; APOPTOSIS; BRAIN; CELL PROLIFERATION; GENE KNOCK-IN TECHNIQUES; GENE KNOCKOUT TECHNIQUES; MICE; NEURONAL PLASTICITY; NEURONS; NUCLEAR LOCALIZATION SIGNALS; PARATHYROID HORMONE-RELATED PROTEIN; PHENOTYPE; SYNAPTIC TRANSMISSION;

MUS;

EID: 84864247712     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041542     Document Type: Article

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