메뉴 건너뛰기




Volumn 90, Issue 8, 2012, Pages 1127-1134

Upregulation of CaMKIIδ during ischaemia- reperfusion is associated with reperfusioninduced arrhythmias and mechanical dysfunction of the rat heart: Involvement of sarcolemmal Ca2+-cycling proteins

Author keywords

Arrhythmias; Ca2+ calmodulin dependent protein kinase II; L type calcium channel; Myocardial ischaemia reperfusion; Sodium calcium exchanger

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE IIDELTA; CALCIUM ION; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

EID: 84864228297     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/Y2012-019     Document Type: Article
Times cited : (11)

References (36)
  • 1
    • 2942596098 scopus 로고    scopus 로고
    • Calmodulin kinase and L-type calcium channels: A recipe for arrhythmias?
    • doi:10.1016/j.tcm.2004.02.005. PMID:15177266
    • Anderson, M.E. 2004. Calmodulin kinase and L-type calcium channels: a recipe for arrhythmias? Trends Cardiovasc. Med. 14(4): 152-161. doi:10.1016/j.tcm.2004.02.005. PMID:15177266.
    • (2004) Trends Cardiovasc. Med , vol.14 , Issue.4 , pp. 152-161
    • Anderson, M.E.1
  • 2
    • 15244345086 scopus 로고    scopus 로고
    • Calmodulin kinase signaling in heart: An intriguing candidate target for therapy of myocardial dysfunction and arrhythmias
    • doi:10.1016/j. pharmthera.2004.11.002. PMID:15781121
    • Anderson, M.E. 2005. Calmodulin kinase signaling in heart: an intriguing candidate target for therapy of myocardial dysfunction and arrhythmias. Pharmacol. Ther. 106(1): 39-55. doi:10.1016/j. pharmthera.2004.11.002. PMID:15781121.
    • (2005) Pharmacol. Ther , vol.106 , Issue.1 , pp. 39-55
    • Anderson, M.E.1
  • 4
    • 80053150840 scopus 로고    scopus 로고
    • Ca (2+)/calmodulin-dependent protein kinase inhibition suppresses post-ischaemic arrhythmogenesis and mediates sinus bradycardic recovery in reperfusion
    • In press. doi:10.1016/j. ijcard.2011.02.038. PMID:21392835
    • Bell, J.R., Curl, C.L., Ip, W.T., and Delbridge, L.M. 2011. Ca (2+)/calmodulin-dependent protein kinase inhibition suppresses post-ischaemic arrhythmogenesis and mediates sinus bradycardic recovery in reperfusion. Int. J. Cardiol., In press. doi:10.1016/j. ijcard.2011.02.038. PMID:21392835.
    • (2011) Int. J. Cardiol
    • Bell, J.R.1    Curl, C.L.2    Ip, W.T.3    Delbridge, L.M.4
  • 5
    • 0022402059 scopus 로고
    • Myocardial reperfusion: A double-edged sword?
    • doi:10. 1172/JCI112160. PMID:4056048
    • Braunwald, E., and Kloner, R.A. 1985. Myocardial reperfusion: a double-edged sword? J. Clin. Invest. 76(5): 1713-1719. doi:10. 1172/JCI112160. PMID:4056048.
    • (1985) J. Clin. Invest , vol.76 , Issue.5 , pp. 1713-1719
    • Braunwald, E.1    Kloner, R.A.2
  • 6
    • 27944487173 scopus 로고    scopus 로고
    • 2+ overload causes mitochondrial-dependent apoptosis in ventricular myocytes
    • doi:10.1161/01.RES. 0000189270.72915.D1. PMID:16210547
    • 2+ overload causes mitochondrial-dependent apoptosis in ventricular myocytes. Circ. Res. 97(10): 1009-1017. doi:10.1161/01.RES. 0000189270.72915.D1. PMID:16210547.
    • (2005) Circ. Res , vol.97 , Issue.10 , pp. 1009-1017
    • Chen, X.1    Zhang, X.2    Kubo, H.3    Harris, D.M.4    Mills, G.D.5    Moyer, J.6
  • 7
    • 0020521890 scopus 로고
    • Potential electrophysiologic mechanisms responsible for dysrhythmias associated with reperfusion of ischaemic myocardium
    • PMID:6305533
    • Corr, P.B., and Witkowski, F.X. 1983. Potential electrophysiologic mechanisms responsible for dysrhythmias associated with reperfusion of ischaemic myocardium. Circulation, 68(2): I16-I24. PMID:6305533.
    • (1983) Circulation , vol.68 , Issue.2
    • Corr, P.B.1    Witkowski, F.X.2
  • 8
    • 0021733560 scopus 로고
    • Arrhythmias associated with reperfusion: Basic insights and clinical relevance
    • PMID:6084147
    • Corr, P.B., and Witkowski, F.X. 1984. Arrhythmias associated with reperfusion: basic insights and clinical relevance. J. Cardiovasc. Pharmacol. 6(Suppl. 6): S903-S909. PMID:6084147.
    • (1984) J. Cardiovasc. Pharmacol , vol.6 , Issue.SUPPL. 6
    • Corr, P.B.1    Witkowski, F.X.2
  • 9
    • 0032127160 scopus 로고    scopus 로고
    • Characterisation, utilisation and clinical relevance of isolated perfused heart models of ischaemia-induced ventricular fibrillation
    • doi:10.1016/S0008-6363(98)00083-2. PMID:9764200
    • Curtis, M.J. 1998. Characterisation, utilisation and clinical relevance of isolated perfused heart models of ischaemia-induced ventricular fibrillation. Cardiovasc. Res. 39(1): 194-215. doi:10.1016/S0008-6363(98)00083-2. PMID:9764200.
    • (1998) Cardiovasc. Res , vol.39 , Issue.1 , pp. 194-215
    • Curtis, M.J.1
  • 10
    • 0033781028 scopus 로고    scopus 로고
    • Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels
    • doi:10.1038/35004052. PMID:10707089
    • Dzhura, I., Wu, Y., Colbran, R.J., Balser, J.R., and Anderson, M.E. 2000. Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels. Nat. Cell Biol. 2(3): 173-177. doi:10.1038/35004052. PMID:10707089.
    • (2000) Nat. Cell Biol , vol.2 , Issue.3 , pp. 173-177
    • Dzhura, I.1    Wu, Y.2    Colbran, R.J.3    Balser, J.R.4    Anderson, M.E.5
  • 11
    • 0003633755 scopus 로고    scopus 로고
    • ILAR (Institute of Laboratory Animal Resources)., NIH Publication No. (revised 1996). National Academy Press, Washington, D.C. Available from
    • ILAR (Institute of Laboratory Animal Resources). 1996. Guide for the Care and Use of Laboratory Animals. NIH Publication No. 85-23 (revised 1996). National Academy Press, Washington, D.C. Available from www.nap.edu/openbook.php?record_id=5140.
    • (1996) Guide for the Care and Use of Laboratory Animals , pp. 23-85
  • 12
  • 13
  • 15
    • 78650819612 scopus 로고    scopus 로고
    • Calmodulin kinase II inhibition prevents arrhythmias in RyR2(R4496C+/-) mice with catecholaminergic polymorphic ventricular tachycardia
    • doi:10.1016/j.yjmcc.2010.10.001. PMID:20937285
    • Liu, N., Ruan, Y., Denegri, M., Bachetti, T., Li, Y., Colombi, B., et al. 2011. Calmodulin kinase II inhibition prevents arrhythmias in RyR2(R4496C+/-) mice with catecholaminergic polymorphic ventricular tachycardia. J. Mol. Cell. Cardiol. 50(1): 214-222. doi:10.1016/j.yjmcc.2010.10.001. PMID:20937285.
    • (2011) J. Mol. Cell. Cardiol , vol.50 , Issue.1 , pp. 214-222
    • Liu, N.1    Ruan, Y.2    Denegri, M.3    Bachetti, T.4    Li, Y.5    Colombi, B.6
  • 16
    • 33846858884 scopus 로고    scopus 로고
    • 2+/calmodulindependent protein kinase (CaMK) in excitation-contraction coupling in the heart
    • doi:10. 1016/j.cardiores.2006.11.005. PMID:17157285
    • 2+/calmodulindependent protein kinase (CaMK) in excitation-contraction coupling in the heart. Cardiovasc. Res. 73(4): 631-640. doi:10. 1016/j.cardiores.2006.11.005. PMID:17157285.
    • (2007) Cardiovasc. Res , vol.73 , Issue.4 , pp. 631-640
    • Maier, L.S.1    Bers, D.M.2
  • 17
    • 74149093364 scopus 로고    scopus 로고
    • Beta-adrenergic receptor stimulated NCX1 upregulation is mediated via a CaMKII/AP-1 signaling pathway in adult cardiomyocytes
    • doi:10.1016/j.yjmcc.2009.11.007. PMID:19945464
    • Mani, S.K., Egan, E.A., Addy, B.K., Grimm, M., Kasiganesan, H., Thiyagarajan, T., et al. 2010. Beta-adrenergic receptor stimulated NCX1 upregulation is mediated via a CaMKII/AP-1 signaling pathway in adult cardiomyocytes. J. Mol. Cell. Cardiol. 48(2): 342-351. doi:10.1016/j.yjmcc.2009.11.007. PMID:19945464.
    • (2010) J. Mol. Cell. Cardiol , vol.48 , Issue.2 , pp. 342-351
    • Mani, S.K.1    Egan, E.A.2    Addy, B.K.3    Grimm, M.4    Kasiganesan, H.5    Thiyagarajan, T.6
  • 18
    • 0021645702 scopus 로고
    • Molecular and biochemical mechanisms underlying the role of calcium ions in malignant ventricular arrhythmias
    • 1 Clinical Aspe, doi:10.1111/j.1749-6632.1984.tb20780.x. PMID:6331248
    • Opie, L.H., and Thandroyen, F.T. 1984. Molecular and biochemical mechanisms underlying the role of calcium ions in malignant ventricular arrhythmias. Ann. N. Y. Acad. Sci. 427(1 Clinical Aspe): 127-139. doi:10.1111/j.1749-6632.1984.tb20780.x. PMID:6331248.
    • (1984) Ann. N. Y. Acad. Sci , vol.427 , pp. 127-139
    • Opie, L.H.1    Thandroyen, F.T.2
  • 19
    • 0033938512 scopus 로고    scopus 로고
    • Ischaemic preconditioning prevents I/R-induced alterations in SR calcium-calmodulin protein kinase II
    • PMID:10843874
    • Osada, M., Netticadan, T., Kawabata, K., Tamura, K., and Dhalla, N.S. 2000. Ischaemic preconditioning prevents I/R-induced alterations in SR calcium-calmodulin protein kinase II. Am. J. Physiol. Heart Circ. Physiol. 278(6): H1791-H1798. PMID:10843874.
    • (2000) Am. J. Physiol. Heart Circ. Physiol , vol.278 , Issue.6
    • Osada, M.1    Netticadan, T.2    Kawabata, K.3    Tamura, K.4    Dhalla, N.S.5
  • 20
    • 68249130547 scopus 로고    scopus 로고
    • Calmodulin kinase II initiates arrhythmogenicity during metabolic acidification in murine hearts
    • doi:10.1111/j.1748-1716.2009.01991.x. PMID:19416122
    • Pedersen, T.H., Gurung, I.S., Grace, A., and Huang, C.L. 2009. Calmodulin kinase II initiates arrhythmogenicity during metabolic acidification in murine hearts. Acta Physiol. (Oxf.), 197(1): 13-25. doi:10.1111/j.1748-1716.2009.01991.x. PMID:19416122.
    • (2009) Acta Physiol. (Oxf.) , vol.197 , Issue.1 , pp. 13-25
    • Pedersen, T.H.1    Gurung, I.S.2    Grace, A.3    Huang, C.L.4
  • 21
    • 0029148993 scopus 로고
    • Brief, intermediate and prolonged ischaemia in the isolated crystalloid perfused rat heart: Relationship between susceptibility to arrhythmias and degree of ultrastructural injury
    • doi:10.1016/0022-2828(95)90016-0. PMID:8523454
    • Ravingerová, T., Tribulová, N., Slezák, J., and Curtis, M.J. 1995. Brief, intermediate and prolonged ischaemia in the isolated crystalloid perfused rat heart: relationship between susceptibility to arrhythmias and degree of ultrastructural injury. J. Mol. Cell. Cardiol. 27(9): 1937-1951. doi:10.1016/0022-2828(95)90016-0. PMID:8523454.
    • (1995) J. Mol. Cell. Cardiol , vol.27 , Issue.9 , pp. 1937-1951
    • Ravingerová, T.1    Tribulová, N.2    Slezák, J.3    Curtis, M.J.4
  • 22
    • 0033213550 scopus 로고    scopus 로고
    • Free oxygen radicals contribute to high incidence of reperfusion-induced arrhythmias in isolated rat heart
    • doi:10.1016/S0024-3205(99) 00449-X. PMID:10576439
    • Ravingerová, T., Slezák, J., Tribulová, J., Džurba, A., Uhrík, B., and Ziegelhoffer, A. 1999. Free oxygen radicals contribute to high incidence of reperfusion-induced arrhythmias in isolated rat heart. Life Sci. 65(18-19): 1927-1930. doi:10.1016/S0024-3205(99) 00449-X. PMID:10576439.
    • (1999) Life Sci , vol.65 , Issue.18-19 , pp. 1927-1930
    • Ravingerová, T.1    Slezák, J.2    Tribulová, J.3    Džurba, A.4    Uhrík, B.5    Ziegelhoffer, A.6
  • 23
    • 74249087588 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure
    • doi:10.1161/CIRCHEARTFAILURE.109.865279. PMID:19919992
    • Sag, C.M., Wadsack, D.P., Khabbazzadeh, S., Abesser, M., Grefe, C., Neumann, K., et al. 2009. Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure. Circ. Heart Fail. 2(6): 664-675. doi:10.1161/CIRCHEARTFAILURE.109.865279. PMID:19919992.
    • (2009) Circ. Heart Fail , vol.2 , Issue.6 , pp. 664-675
    • Sag, C.M.1    Wadsack, D.P.2    Khabbazzadeh, S.3    Abesser, M.4    Grefe, C.5    Neumann, K.6
  • 24
    • 0042358922 scopus 로고    scopus 로고
    • Role of dual-site phospholamban phosphorylation in the stunned heart: Insights from phospholamban site-specific mutants
    • PMID:12763747
    • Said, M., Vittone, L., Mundina-Weilenmann, C., Ferrero, P., Kranias, E.G., and Mattiazzi, A. 2003. Role of dual-site phospholamban phosphorylation in the stunned heart: insights from phospholamban site-specific mutants. Am. J. Physiol. Heart Circ. Physiol. 285(3): H1198-H1205. PMID:12763747.
    • (2003) Am. J. Physiol. Heart Circ. Physiol , vol.285 , Issue.3
    • Said, M.1    Vittone, L.2    Mundina-Weilenmann, C.3    Ferrero, P.4    Kranias, E.G.5    Mattiazzi, A.6
  • 25
    • 80055115759 scopus 로고    scopus 로고
    • Calcium-calmodulin dependent protein kinase II (CaMKII): A main signal responsible for early reperfusion arrhythmias
    • doi:10.1016/j.yjmcc.2011.08.010. PMID:21888910
    • Said, M., Becerra, R., Valverde, C.A., Kaetzel, M.A., Dedman, J.R., Mundiña-Weilenmann, C., et al. 2011. Calcium-calmodulin dependent protein kinase II (CaMKII): a main signal responsible for early reperfusion arrhythmias. J. Mol. Cell. Cardiol. 51(6): 936-944. doi:10.1016/j.yjmcc.2011.08.010. PMID:21888910.
    • (2011) J. Mol. Cell. Cardiol , vol.51 , Issue.6 , pp. 936-944
    • Said, M.1    Becerra, R.2    Valverde, C.A.3    Kaetzel, M.A.4    Dedman, J.R.5    Mundiña-Weilenmann, C.6
  • 26
    • 77952669275 scopus 로고    scopus 로고
    • The signalling pathway of camk IImediated apoptosis and necrosis in the ischaemia/reperfusion injury
    • doi:10.1016/j. yjmcc.2009.12.015. PMID:20060004
    • Salas, M.A., Valverde, C.A., Sánchez, G., Said, M., Rodriguez, J.S., Portiansky, E.L., et al. 2010. The signalling pathway of camk IImediated apoptosis and necrosis in the ischaemia/reperfusion injury. J. Mol. Cell. Cardiol. 48(6): 1298-1306. doi:10.1016/j. yjmcc.2009.12.015. PMID:20060004.
    • (2010) J. Mol. Cell. Cardiol , vol.48 , Issue.6 , pp. 1298-1306
    • Salas, M.A.1    Valverde, C.A.2    Sánchez, G.3    Said, M.4    Rodriguez, J.S.5    Portiansky, E.L.6
  • 27
    • 0034934941 scopus 로고    scopus 로고
    • Role of the reverse mode of the Na+/Ca2+ exchanger in reoxygenation-induced cardiomyocyte injury
    • doi:10.1016/S0008-6363 (01)00282-6. PMID:11470463
    • Schäfer, C., Ladilov, Y., Inserte, J., Schäfer, M., Haffner, S., Garcia-Dorado, D., and Piper, H.M. 2001. Role of the reverse mode of the Na+/Ca2+ exchanger in reoxygenation-induced cardiomyocyte injury. Cardiovasc. Res. 51(2): 241-250. doi:10.1016/S0008-6363 (01)00282-6. PMID:11470463.
    • (2001) Cardiovasc. Res , vol.51 , Issue.2 , pp. 241-250
    • Schäfer, C.1    Ladilov, Y.2    Inserte, J.3    Schäfer, M.4    Haffner, S.5    Garcia-Dorado, D.6    Piper, H.M.7
  • 30
    • 33846862701 scopus 로고    scopus 로고
    • CaMKII inhibition protects against necrosis and apoptosis in irreversible ischaemia-reperfusion injury
    • doi:10.1016/j.cardiores.2006.12. 003. PMID:17217936
    • Vila-Petroff, M., Salas, M.A., Said, M., Valverde, C.A., Sapia, L., Portiansky, E., et al. 2007. CaMKII inhibition protects against necrosis and apoptosis in irreversible ischaemia-reperfusion injury. Cardiovasc. Res. 73(4): 689-698. doi:10.1016/j.cardiores.2006.12. 003. PMID:17217936.
    • (2007) Cardiovasc. Res , vol.73 , Issue.4 , pp. 689-698
    • Vila-Petroff, M.1    Salas, M.A.2    Said, M.3    Valverde, C.A.4    Sapia, L.5    Portiansky, E.6
  • 31
    • 77953359282 scopus 로고    scopus 로고
    • Ca(2+)/calmodulindependent protein kinase II contributes to intracellular pH recovery from acidosis via Na(+)/H(+) exchanger activation
    • doi:10.1016/j.yjmcc.2009. 12.007. PMID:20026127
    • Vila-Petroff, M., Mundiña-Weilenmann, C., Lezcano, N., Snabaitis, A.K., Huergo, M.A., Valverde, C.A., et al. 2010. Ca(2+)/calmodulindependent protein kinase II contributes to intracellular pH recovery from acidosis via Na(+)/H(+) exchanger activation. J. Mol. Cell. Cardiol. 49(1): 106-112. doi:10.1016/j.yjmcc.2009. 12.007. PMID:20026127.
    • (2010) J. Mol. Cell. Cardiol , vol.49 , Issue.1 , pp. 106-112
    • Vila-Petroff, M.1    Mundiña-Weilenmann, C.2    Lezcano, N.3    Snabaitis, A.K.4    Huergo, M.A.5    Valverde, C.A.6
  • 32
    • 85047679058 scopus 로고
    • The Lambeth conventions: Guidelines for the study of arrhythmias in ischaemia infarction, and reperfusion
    • doi:10.1093/cvr/22.7.447. PMID:3252968
    • Walker, M.J., Curtis, M.J., Hearse, D.J., Campbell, R.W., Janse, M.J., Yellon, D.M., et al. 1988. The Lambeth conventions: guidelines for the study of arrhythmias in ischaemia infarction, and reperfusion. Cardiovasc. Res. 22(7): 447-455. doi:10.1093/cvr/22.7.447. PMID:3252968.
    • (1988) Cardiovasc. Res , vol.22 , Issue.7 , pp. 447-455
    • Walker, M.J.1    Curtis, M.J.2    Hearse, D.J.3    Campbell, R.W.4    Janse, M.J.5    Yellon, D.M.6
  • 33
    • 0037015257 scopus 로고    scopus 로고
    • Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy
    • doi:10. 1161/01.CIR.0000027583.73268.E7. PMID:12208807
    • Wu, Y., Temple, J., Zhang, R., Dzhura, I., Zhang, W., Trimble, R., et al. 2002. Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy. Circulation, 106(10): 1288-1293. doi:10. 1161/01.CIR.0000027583.73268.E7. PMID:12208807.
    • (2002) Circulation , vol.106 , Issue.10 , pp. 1288-1293
    • Wu, Y.1    Temple, J.2    Zhang, R.3    Dzhura, I.4    Zhang, W.5    Trimble, R.6
  • 34
    • 31444441035 scopus 로고    scopus 로고
    • 2+ transient responses to pacing in ventricular myocytes from mice with genetic calmodulin kinase II inhibition
    • doi:10.1016/j. yjmcc.2005.11.005. PMID:16413575
    • 2+ transient responses to pacing in ventricular myocytes from mice with genetic calmodulin kinase II inhibition. J. Mol. Cell. Cardiol. 40(2): 213-223. doi:10.1016/j. yjmcc.2005.11.005. PMID:16413575.
    • (2006) J. Mol. Cell. Cardiol , vol.40 , Issue.2 , pp. 213-223
    • Wu, Y.1    Shintani, A.2    Grueter, C.3    Zhang, R.4    Hou, Y.5    Yang, J.6
  • 35
    • 33845403131 scopus 로고    scopus 로고
    • Calmodulin kinase II inhibition protects against myocardial cell apoptosis in vivo
    • doi:10.1152/ajpheart.00353. 2006. PMID:16861697
    • Yang, Y., Zhu, W.Z., Joiner, M.L., Zhang, R., Oddis, C.V., Hou, Y., et al. 2006. Calmodulin kinase II inhibition protects against myocardial cell apoptosis in vivo. Am. J. Physiol. Heart Circ. Physiol. 291(6): H3065-H3075. doi:10.1152/ajpheart.00353. 2006. PMID:16861697.
    • (2006) Am. J. Physiol. Heart Circ. Physiol , vol.291 , Issue.6
    • Yang, Y.1    Zhu, W.Z.2    Joiner, M.L.3    Zhang, R.4    Oddis, C.V.5    Hou, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.