Ca 2+/calmodulin-dependent protein kinase inhibition suppresses post-ischemic arrhythmogenesis and mediates sinus bradycardic recovery in reperfusion

International Journal of Cardiology

Volumn 159, Issue 2, 2012, Pages 112-118

  Bell, James R ^a   Curl, Claire L ^a   Ip, Wendy T K ^a   Delbridge, Lea M D ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Arrhythmia; Ca2+ calmodulin dependent protein kinase; Cardiac function; Ischemia reperfusion

Indexed keywords

2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; LACTATE DEHYDROGENASE; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; NIFEDIPINE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; PROTEIN KINASE INHIBITOR;

ANIMAL TISSUE; ARRHYTHMOGENESIS; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; ENZYME INHIBITION; HEART CONTRACTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBER MEMBRANE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART RATE; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; MALE; MEMBRANE RUPTURE; NONHUMAN; PERFUSION PRESSURE; PRIORITY JOURNAL; RAT; SINUS BRADYCARDIA; ANIMAL; BRADYCARDIA; CONVALESCENCE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HEART ARRHYTHMIA; METABOLISM; METHODOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ARRHYTHMIAS, CARDIAC; BRADYCARDIA; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; MALE; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION;

EID: 80053150840     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2011.02.038     Document Type: Article

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