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Volumn 5, Issue , 2012, Pages

Molecular functions of metallothionein and its role in hematological malignancies

Author keywords

Hematological malignancies; Metallothionein (MT); Molecular function

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 NITROPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BLEOMYCIN; CISPLATIN; CYTARABINE; ETOPOSIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUKEMIA INHIBITORY FACTOR; MELPHALAN; METALLOTHIONEIN I; METALLOTHIONEIN II; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SCAVENGER;

EID: 84864212994     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/1756-8722-5-41     Document Type: Review
Times cited : (60)

References (79)
  • 1
    • 33947463103 scopus 로고
    • A cadmium protein from equine kidney cortex
    • 10.1021/ja01574a064
    • A cadmium protein from equine kidney cortex. M Margoshes, BL Vallee, J Am Chem Soc 1957 79 17 4813 1814 10.1021/ja01574a064
    • (1957) J Am Chem Soc , vol.79 , Issue.17 , pp. 4813-1814
    • Margoshes, M.1    Vallee, B.L.2
  • 3
    • 0022555879 scopus 로고
    • Metallothionein
    • Metallothionein. DH Hamer, Annu Rev Biochem 1986 55 913 951 10.1146/annurev.bi.55.070186.004405 3527054 (Pubitemid 16070791)
    • (1986) Annual Review of Biochemistry , vol.VOL. 55 , pp. 913-951
    • Hamer, D.H.1
  • 4
    • 0025340641 scopus 로고
    • Metallothionein and the trace minerals
    • 10.1146/annurev.nu.10.070190.000431 2200476
    • Metallothionein and the trace minerals. I Bremner, JH Beattie, Annu Rev Nutr 1990 10 63 83 10.1146/annurev.nu.10.070190.000431 2200476
    • (1990) Annu Rev Nutr , vol.10 , pp. 63-83
    • Bremner, I.1    Beattie, J.H.2
  • 5
    • 0035210844 scopus 로고    scopus 로고
    • A distinct role for apoptosis in the changes in lymphopoiesis and myelopoiesis created by deficiencies in zinc
    • DOI 10.1096/fj.01-0430rev
    • A distinct role for apoptosis in the changes in lymphopoiesis and myelopoiesis created by deficiencies in zinc. PJ Fraker, LE King, FASEB J 2001 15 14 2572 2578 10.1096/fj.01-0430rev 11726532 (Pubitemid 33138128)
    • (2001) FASEB Journal , vol.15 , Issue.14 , pp. 2572-2578
    • Fraker, P.J.1    King, L.E.2
  • 6
    • 0030845535 scopus 로고    scopus 로고
    • Metallothionein in physiological and physiopathological processes
    • Metallothionein in physiological and physiopathological processes. P Moffatt, F Denizeau, Drug Metab Rev. 1997 29 1-2 261 307 9187522 (Pubitemid 27293613)
    • (1997) Drug Metabolism Reviews , vol.29 , Issue.1-2 , pp. 261-307
    • Moffatt, P.1    Denizeau, F.2
  • 7
    • 0021724845 scopus 로고
    • Regulation, linkage, and sequence of mouse metallothionein I and II genes
    • Regulation, linkage, and sequence of mouse metallothionein I and II genes. PF Searle, BL Davison, GW Stuart, TM Wilkie, G Norstedt, RD Palmiter, Mol Cell Biol 1984 4 7 1221 1230 6095054 (Pubitemid 16242517)
    • (1984) Molecular and Cellular Biology , vol.4 , Issue.7 , pp. 1221-1230
    • Searle, P.F.1    Davison, B.L.2    Stuart, G.W.3
  • 8
    • 0025768860 scopus 로고
    • The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein
    • 10.1016/0896-6273(91)90272-2 1873033
    • The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein. Y Uchida, K Takio, K Titani, Y Ihara, M Tomonaga, Neuron 1991 7 2 337 347 10.1016/0896-6273(91)90272- 2 1873033
    • (1991) Neuron , vol.7 , Issue.2 , pp. 337-347
    • Uchida, Y.1    Takio, K.2    Titani, K.3    Ihara, Y.4    Tomonaga, M.5
  • 9
    • 0028289610 scopus 로고
    • Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia
    • DOI 10.1021/bi00189a029
    • Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia. CJ Quaife, SD Findley, JC Erickson, GJ Froelick, EJ Kelly, BP Zambrowicz, et al. Biochemistry 1994 33 23 7250 7259 10.1021/bi00189a029 8003488 (Pubitemid 24208763)
    • (1994) Biochemistry , vol.33 , Issue.23 , pp. 7250-7259
    • Quaife, C.J.1    Findley, S.D.2    Erickson, J.C.3    Froelick, G.J.4    Kelly, E.J.5    Zambrowicz, B.P.6    Palmiter, R.D.7
  • 10
    • 0023862975 scopus 로고
    • Regulation of human metallothionein (MT) genes. Differential expression of MTI-F, MTI-G, and MTII-A genes in the hepatoblastoma cell line (HepG2)
    • Regulation of human metallothionein (MT) genes. Differential expression of MTI-F, MTI-G, and MTII-A genes in the hepatoblastoma cell line (HepG2). C Sadhu, L Gedamu, J Biol Chem 1988 263 6 2679 2684 2830259 (Pubitemid 18062910)
    • (1988) Journal of Biological Chemistry , vol.263 , Issue.6 , pp. 2679-2684
    • Sadhu, C.1    Gedamu, L.2
  • 11
    • 0019932125 scopus 로고
    • Human metallothionein genes - primary structure of the metallothionein-II gene and a related processed gene
    • DOI 10.1038/299797a0
    • Human metallothionein genes-primary structure of the metallothionein-II gene and a related processed gene. M Karin, RI Richards, Nature 1982 299 5886 797 802 10.1038/299797a0 7133118 (Pubitemid 12003298)
    • (1982) Nature , vol.299 , Issue.5886 , pp. 797-802
    • Karin, M.1    Richards, R.I.2
  • 12
    • 0021173920 scopus 로고
    • Structural and functional analysis of the human metallothionein-I(A) gene: Differential induction by metal ions and glucocorticoids
    • Structural and functional analysis of the human metallothionein-IA gene: differential induction by metal ions and glucocorticoids. RI Richards, A Heguy, M Karin, Cell 1984 37 1 263 272 10.1016/0092-8674(84)90322-2 6327055 (Pubitemid 14079858)
    • (1984) Cell , vol.37 , Issue.1 , pp. 263-272
    • Richards, R.I.1    Heguy, A.2    Kain, M.3
  • 13
    • 0022648524 scopus 로고
    • Structure, organization, and regulation of human metallothionein I(F) gene: Differential and cell-type-specific expression in response to heavy metals and glucocorticoids
    • Structure, organization, and regulation of human metallothionein IF gene: differential and cell-type-specific expression in response to heavy metals and glucocorticoids. U Varshney, N Jahroudi, R Foster, L Gedamu, Mol Cell Biol 1986 6 1 26 37 3023827 (Pubitemid 16182080)
    • (1986) Molecular and Cellular Biology , vol.6 , Issue.1 , pp. 26-37
    • Varshney, U.1    Jahroudi, N.2    Foster, R.3    Gedamu, L.4
  • 18
    • 0029985755 scopus 로고    scopus 로고
    • Transgenic mice that overexpress metallothionein-I resist dietary zinc deficiency
    • Transgenic mice that overexpress metallothionein-I resist dietary zinc deficiency. T Dalton, K Fu, RD Palmiter, GK Andrews, J Nutr 1996 126 4 825 833 8613884 (Pubitemid 26100951)
    • (1996) Journal of Nutrition , vol.126 , Issue.4 , pp. 825-833
    • Dalton, T.1    Fu, K.2    Palmiter, R.D.3    Andrews, G.K.4
  • 19
    • 63649149462 scopus 로고    scopus 로고
    • The role of metallothionein in oncogenesis and cancer prognosis
    • 10.1016/j.proghi.2008.10.001 19348910
    • The role of metallothionein in oncogenesis and cancer prognosis. MO Pedersen, A Larsen, M Stoltenberg, M Penkowa, Prog Histochem Cytochem 2009 44 1 29 64 10.1016/j.proghi.2008.10.001 19348910
    • (2009) Prog Histochem Cytochem , vol.44 , Issue.1 , pp. 29-64
    • Pedersen, M.O.1    Larsen, A.2    Stoltenberg, M.3    Penkowa, M.4
  • 20
    • 4344639738 scopus 로고    scopus 로고
    • Metallothionein expression in human neoplasia
    • DOI 10.1111/j.1365-2559.2004.01922.x
    • Metallothionein expression in human neoplasia. SE Theocharis, AP Margeli, JT Klijanienko, GP Kouraklis, Histopathology 2004 45 2 103 118 10.1111/j.1365-2559.2004.01922.x 15279628 (Pubitemid 39120406)
    • (2004) Histopathology , vol.45 , Issue.2 , pp. 103-118
    • Theocharis, S.E.1    Margeli, A.P.2    Klijanienko, J.T.3    Kouraklis, G.P.4
  • 22
    • 0142244190 scopus 로고    scopus 로고
    • Differential Expression of Metallothionein 1 and 2 Isoforms in Breast Cancer Lines with Different Invasive Potential: Identification of a Novel Nonsilent Metallothionein-1H Mutant Variant
    • Differential expression of metallothionein 1 and 2 isoforms in breast cancer lines with different invasive potential: identification of a novel nonsilent metallothionein-1H mutant variant. SK Tai, OJ Tan, VT Chow, R Jin, JL Jones, PH Tan, et al. Am J Pathol 2003 163 5 2009 2019 10.1016/S0002-9440(10) 63559-6 14578200 (Pubitemid 37310031)
    • (2003) American Journal of Pathology , vol.163 , Issue.5 , pp. 2009-2019
    • Tai, S.-K.1    Tan, O.J.-K.2    Chow, V.T.-K.3    Jin, R.4    Jones, J.L.5    Tan, P.-H.6    Jayasurya, A.7    Bay, B.-H.8
  • 23
    • 0034479840 scopus 로고    scopus 로고
    • Metallothionein expression prevents apoptosis. II: Evaluation of the role of metallothionein expression on the chemotherapy-induced apoptosis during the treatment of acute leukemia
    • 11205280
    • Metallothionein expression prevents apoptosis. II: Evaluation of the role of metallothionein expression on the chemotherapy-induced apoptosis during the treatment of acute leukemia. GT Tsangaris, J Vamvoukakis, I Politis, AC Kattamis, F Tzortzatou-Stathopoulou, Anticancer Res 2000 20 6B 4407 4411 11205280
    • (2000) Anticancer Res , vol.20 , Issue.6 B , pp. 4407-4411
    • Tsangaris, G.T.1    Vamvoukakis, J.2    Politis, I.3    Kattamis, A.C.4    Tzortzatou-Stathopoulou, F.5
  • 24
    • 77957032517 scopus 로고    scopus 로고
    • Prognostic classification of patients with acute lymphoblastic leukemia by using gene copy number profiles identified from array-based comparative genomic hybridization data
    • 10.1016/j.leukres.2010.02.031 20303590
    • Prognostic classification of patients with acute lymphoblastic leukemia by using gene copy number profiles identified from array-based comparative genomic hybridization data. A Usvasalo, E Elonen, UM Saarinen-Pihkala, R Raty, A Harila-Saari, P Koistinen, et al. Leuk Res 2010 34 11 1476 1482 10.1016/j.leukres.2010.02.031 20303590
    • (2010) Leuk Res , vol.34 , Issue.11 , pp. 1476-1482
    • Usvasalo, A.1    Elonen, E.2    Saarinen-Pihkala, U.M.3    Raty, R.4    Harila-Saari, A.5    Koistinen, P.6
  • 25
    • 0031830575 scopus 로고    scopus 로고
    • Multiple resistance mechanisms in acute nonlymphoblastic leukemia (ANLL)
    • Multiple resistance mechanisms in acute nonlymphoblastic leukemia (ANLL). A Sauerbrey, F Zintl, J Hermann, M Volm, Anticancer Res 1998 18 2B 1231 1236 9615793 (Pubitemid 28234022)
    • (1998) Anticancer Research , vol.18 , Issue.2 , pp. 1231-1236
    • Sauerbrey, A.1    Zintl, F.2    Hermann, J.3    Volm, M.4
  • 26
    • 77951220872 scopus 로고    scopus 로고
    • Metallothionein-1 isoforms and vimentin are direct PU.1 downstream target genes in leukemia cells
    • 10.1074/jbc.M109.095810 20139074
    • Metallothionein-1 isoforms and vimentin are direct PU.1 downstream target genes in leukemia cells. A Imoto, M Okada, T Okazaki, H Kitasato, H Harigae, S Takahashi, J Biol Chem 2010 285 14 10300 10309 10.1074/jbc.M109.095810 20139074
    • (2010) J Biol Chem , vol.285 , Issue.14 , pp. 10300-10309
    • Imoto, A.1    Okada, M.2    Okazaki, T.3    Kitasato, H.4    Harigae, H.5    Takahashi, S.6
  • 27
    • 33751194655 scopus 로고    scopus 로고
    • Prognostic significance of metallothionein in B-cell lymphomas
    • 10.1182/blood-2006-04-015305 16868254
    • Prognostic significance of metallothionein in B-cell lymphomas. CB Poulsen, R Borup, N Borregaard, FC Nielsen, MB Moller, E Ralfkiaer, Blood 2006 108 10 3514 3519 10.1182/blood-2006-04-015305 16868254
    • (2006) Blood , vol.108 , Issue.10 , pp. 3514-3519
    • Poulsen, C.B.1    Borup, R.2    Borregaard, N.3    Nielsen, F.C.4    Moller, M.B.5    Ralfkiaer, E.6
  • 28
    • 1542345411 scopus 로고    scopus 로고
    • Expression of metallothionein (MT) and gluthatione s-transferase pi (SGTP) in the bone marrow of patients with myeloproliferative disorders (MPD)
    • Expression of metallothionein (MT) and gluthatione s-transferase pi (SGTP) in the bone marrow of patients with myeloproliferative disorders (MPD). T Wrobel, G Mazur, P Dziegiel, P Surowiak, K Kuliczkowski, M Zabel, Folia Morphol (Warsz). 2004 63 1 129 131 (Pubitemid 38325231)
    • (2004) Folia Morphologica , vol.63 , Issue.1 , pp. 129-131
    • Wrobel, T.1    Mazur, G.2    Dziegiel, P.3    Surowiak, P.4    Kuliczkowski, K.5    Zabel, M.6
  • 29
    • 61349088131 scopus 로고    scopus 로고
    • Metallothionein as a useful marker in Hodgkin lymphoma subclassification
    • 10.1080/10428190802699340 19199157
    • Metallothionein as a useful marker in Hodgkin lymphoma subclassification. M Penkowa, BL Sorensen, SL Nielsen, PB Hansen, Leuk Lymphoma. 2009 50 2 200 210 10.1080/10428190802699340 19199157
    • (2009) Leuk Lymphoma. , vol.50 , Issue.2 , pp. 200-210
    • Penkowa, M.1    Sorensen, B.L.2    Nielsen, S.L.3    Hansen, P.B.4
  • 30
    • 0032996361 scopus 로고    scopus 로고
    • Metallothionein in radiation exposure: Its induction and protective role
    • DOI 10.1016/S0300-483X(98)00150-4, PII S0300483X98001504
    • Metallothionein in radiation exposure: its induction and protective role. L Cai, M Satoh, C Tohyama, MG Cherian, Toxicology 1999 132 2-3 85 98 10433372 (Pubitemid 29121947)
    • (1999) Toxicology , vol.132 , Issue.2-3 , pp. 85-98
    • Cai, L.1    Satoh, M.2    Tohyama, C.3    Cherian, M.G.4
  • 31
    • 0027533507 scopus 로고
    • Oxygen free radicals and metallothionein
    • DOI 10.1016/0891-5849(93)90029-T
    • Oxygen free radicals and metallothionein. M Sato, I Bremner, Free Radic Biol Med 1993 14 3 325 337 10.1016/0891-5849(93)90029-T 8458590 (Pubitemid 23066373)
    • (1993) Free Radical Biology and Medicine , vol.14 , Issue.3 , pp. 325-337
    • Sato, M.1    Bremner, I.2
  • 32
    • 0032495227 scopus 로고    scopus 로고
    • + release
    • DOI 10.1016/S0006-8993(98)00947-0, PII S0006899398009470
    • Induction of astrocyte metallothioneins (MTs) by zinc confers resistance against the acute cytotoxic effects of methylmercury on cell swelling, Na+uptake, and K+release. M Aschner, DR Conklin, CP Yao, JW Allen, KH Tan, Brain Res. 1998 813 2 254 261 10.1016/S0006-8993(98)00947-0 9838151 (Pubitemid 29009641)
    • (1998) Brain Research , vol.813 , Issue.2 , pp. 254-261
    • Aschner, M.1    Conklin, D.R.2    Yao, C.P.3    Allen, J.W.4    Tan, K.H.5
  • 33
    • 0029167742 scopus 로고
    • Metallothionein protects DNA from copper-induced but not iron-induced cleavage in vitro
    • 10.1016/0009-2797(94)03585-V 7728904
    • Metallothionein protects DNA from copper-induced but not iron-induced cleavage in vitro. L Cai, J Koropatnick, MG Cherian, Chem Biol Interact. 1995 96 2 143 155 10.1016/0009-2797(94)03585-V 7728904
    • (1995) Chem Biol Interact. , vol.96 , Issue.2 , pp. 143-155
    • Cai, L.1    Koropatnick, J.2    Cherian, M.G.3
  • 35
    • 34548145885 scopus 로고    scopus 로고
    • Downregulated expression of metallothionein and its clinicopathological significance in hepatocellular carcinoma
    • DOI 10.1111/j.1872-034X.2007.00113.x
    • Downregulated expression of metallothionein and its clinicopathological significance in hepatocellular carcinoma. X Tao, JM Zheng, AM Xu, XF Chen, SH Zhang, Hepatol Res 2007 37 10 820 827 10.1111/j.1872-034X.2007.00113.x 17517078 (Pubitemid 47308224)
    • (2007) Hepatology Research , vol.37 , Issue.10 , pp. 820-827
    • Tao, X.1    Zheng, J.-M.2    Xu, A.-M.3    Chen, X.-F.4    Zhang, S.-H.5
  • 36
    • 0028836796 scopus 로고
    • Cell cycle regulation of metallothionein in human colonic cancer cells
    • 10.1073/pnas.92.2.579 7831333
    • Cell cycle regulation of metallothionein in human colonic cancer cells. WW Nagel, BL Vallee, Proc Natl Acad Sci U S A 1995 92 2 579 583 10.1073/pnas.92.2.579 7831333
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.2 , pp. 579-583
    • Nagel, W.W.1    Vallee, B.L.2
  • 37
    • 0025793931 scopus 로고
    • Localization of metallothionein in nuclei of growing primary cultured adult rat hepatocytes
    • 10.1016/0014-5793(91)80597-V 2044762
    • Localization of metallothionein in nuclei of growing primary cultured adult rat hepatocytes. K Tsujikawa, T Imai, M Kakutani, Y Kayamori, T Mimura, N Otaki, et al. FEBS Lett 1991 283 2 239 242 10.1016/0014-5793(91)80597-V 2044762
    • (1991) FEBS Lett , vol.283 , Issue.2 , pp. 239-242
    • Tsujikawa, K.1    Imai, T.2    Kakutani, M.3    Kayamori, Y.4    Mimura, T.5    Otaki, N.6
  • 38
    • 0035871125 scopus 로고    scopus 로고
    • Influence of metallothionein-1 localization on its function
    • DOI 10.1042/0264-6021:3550473
    • Influence of metallothionein-1 localization on its function. M Levadoux-Martin, JE Hesketh, JH Beattie, HM Wallace, Biochem J 2001 355 Pt 2 473 479 11284736 (Pubitemid 32397808)
    • (2001) Biochemical Journal , vol.355 , Issue.2 , pp. 473-479
    • Levadoux-Martin, M.1    Hesketh, J.E.2    Beattie, J.H.3    Wallace, H.M.4
  • 39
    • 0030711622 scopus 로고    scopus 로고
    • Metallothionein accretion in human hepatic cells is linked to cellular proliferation
    • Metallothionein accretion in human hepatic cells is linked to cellular proliferation. R Studer, CP Vogt, M Cavigelli, PE Hunziker, JH Kagi, Biochem J 1997 328 Pt 1 63 67 9359834 (Pubitemid 27499440)
    • (1997) Biochemical Journal , vol.328 , Issue.1 , pp. 63-67
    • Studer, R.1    Vogt, C.P.2    Cavigelli, M.3    Hunziker, P.E.4    Kagi, J.H.R.5
  • 41
    • 0030006123 scopus 로고    scopus 로고
    • Reversible zinc exchange between metallothionein and the estrogen receptor zinc finger
    • DOI 10.1016/0014-5793(96)00356-0
    • Reversible zinc exchange between metallothionein and the estrogen receptor zinc finger. DF Cano-Gauci, B Sarkar, FEBS Lett 1996 386 1 1 4 10.1016/0014-5793(96)00356-0 8635592 (Pubitemid 26143789)
    • (1996) FEBS Letters , vol.386 , Issue.1 , pp. 1-4
    • Cano-Gauci, D.F.1    Sarkar, B.2
  • 43
    • 0034597536 scopus 로고    scopus 로고
    • Metalloregulation of the tumor suppressor protein p53: Zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells
    • 10.1038/sj.onc.1203907 11077439
    • Metalloregulation of the tumor suppressor protein p53: zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells. C Meplan, MJ Richard, P Hainaut, Oncogene 2000 19 46 5227 5236 10.1038/sj.onc.1203907 11077439
    • (2000) Oncogene , vol.19 , Issue.46 , pp. 5227-5236
    • Meplan, C.1    Richard, M.J.2    Hainaut, P.3
  • 44
    • 0032732342 scopus 로고    scopus 로고
    • Metal ions as regulators of the conformation and function of the tumour suppressor protein p53: Implications for carcinogenesis
    • 10.1017/S0029665199000749 10604188
    • Metal ions as regulators of the conformation and function of the tumour suppressor protein p53: implications for carcinogenesis. C Meplan, G Verhaegh, MJ Richard, P Hainaut, Proc Nutr Soc 1999 58 3 565 571 10.1017/S0029665199000749 10604188
    • (1999) Proc Nutr Soc , vol.58 , Issue.3 , pp. 565-571
    • Meplan, C.1    Verhaegh, G.2    Richard, M.J.3    Hainaut, P.4
  • 45
    • 0029996408 scopus 로고    scopus 로고
    • Nucleophilic distribution of metallothionein in human tumor cells
    • DOI 10.1006/excr.1996.0146
    • Nucleophilic distribution of metallothionein in human tumor cells. ES Woo, Y Kondo, SC Watkins, DG Hoyt, JS Lazo, Exp Cell Res. 1996 224 2 365 371 10.1006/excr.1996.0146 8612713 (Pubitemid 26140570)
    • (1996) Experimental Cell Research , vol.224 , Issue.2 , pp. 365-371
    • Woo, E.S.1    Kondo, Y.2    Watkins, S.C.3    Hoyt, D.G.4    Lazo, J.S.5
  • 46
    • 0025976912 scopus 로고
    • Thionein (apometallothionein) can modulate DNA binding and transcription activation by zinc finger containing factor Sp1
    • 10.1016/0014-5793(91)80175-3 2001744
    • Thionein (apometallothionein) can modulate DNA binding and transcription activation by zinc finger containing factor Sp1. J Zeng, R Heuchel, W Schaffner, JH Kagi, FEBS Lett 1991 279 2 310 312 10.1016/0014-5793(91)80175-3 2001744
    • (1991) FEBS Lett , vol.279 , Issue.2 , pp. 310-312
    • Zeng, J.1    Heuchel, R.2    Schaffner, W.3    Kagi, J.H.4
  • 48
    • 57349137262 scopus 로고    scopus 로고
    • Role of metallothionein as a protective factor against radiation carcinogenesis
    • 10.2131/jts.33.651 19043287
    • Role of metallothionein as a protective factor against radiation carcinogenesis. K Shibuya, N Nishimura, JS Suzuki, C Tohyama, A Naganuma, M Satoh, J Toxicol Sci 2008 33 5 651 655 10.2131/jts.33.651 19043287
    • (2008) J Toxicol Sci , vol.33 , Issue.5 , pp. 651-655
    • Shibuya, K.1    Nishimura, N.2    Suzuki, J.S.3    Tohyama, C.4    Naganuma, A.5    Satoh, M.6
  • 49
    • 17744409665 scopus 로고    scopus 로고
    • The protein thiol metallothionein as an antioxidant and protectant against antineoplastic drugs
    • DOI 10.1016/S0009-2797(97)00165-8, PII S0009279797001658
    • The protein thiol metallothionein as an antioxidant and protectant against antineoplastic drugs. JS Lazo, SM Kuo, ES Woo, BR Pitt, Chem Biol Interact. 1998 111-112 255 262 21621526 (Pubitemid 28271949)
    • (1998) Chemico-Biological Interactions , vol.111-112 , pp. 255-262
    • Lazo, J.S.1    Kuo, S.-M.2    Woo, E.S.3    Pitt, B.R.4
  • 52
    • 0030798331 scopus 로고    scopus 로고
    • Cadmium-induced oxidative cellular damage in human fetal lung fibroblasts (MRC-5 cells)
    • Cadmium-induced oxidative cellular damage in human fetal lung fibroblasts (MRC-5 cells). CF Yang, HM Shen, Y Shen, ZX Zhuang, CN Ong, Environ Health Perspect. 1997 105 7 712 716 10.1289/ehp.97105712 9294717 (Pubitemid 27450331)
    • (1997) Environmental Health Perspectives , vol.105 , Issue.7 , pp. 712-716
    • Yang, C.-F.1    Shen, H.-M.2    Shen, Y.3    Zhuang, Z.-X.4    Ong, C.-N.5
  • 53
    • 0032101104 scopus 로고    scopus 로고
    • Activation of nuclear factor κB: Potential role in metallothionein- mediated mitogenic response
    • Activation of nuclear factor kappaB: potential role in metallothionein-mediated mitogenic response. AB Abdel-Mageed, KC Agrawal, Cancer Res 1998 58 11 2335 2338 9622069 (Pubitemid 28252689)
    • (1998) Cancer Research , vol.58 , Issue.11 , pp. 2335-2338
    • Abdel-Mageed, A.B.1    Agrawal, K.C.2
  • 54
    • 0033038019 scopus 로고    scopus 로고
    • Regulatory role of metallothionein in NF-κB activation
    • DOI 10.1016/S0014-5793(99)00839-X, PII S001457939900839X
    • Regulatory role of metallothionein in NF-kappaB activation. A Sakurai, S Hara, N Okano, Y Kondo, J Inoue, N Imura, FEBS Lett 1999 455 1-2 55 58 10428471 (Pubitemid 29322781)
    • (1999) FEBS Letters , vol.455 , Issue.1-2 , pp. 55-58
    • Sakurai, A.1    Hara, S.2    Okano, N.3    Kondo, Y.4    Inoue, J.-I.5    Imura, N.6
  • 56
    • 0029022588 scopus 로고
    • Metallothionein null cells have increased sensitivity to anticancer drugs
    • 7743495
    • Metallothionein null cells have increased sensitivity to anticancer drugs. Y Kondo, ES Woo, AE Michalska, KH Choo, JS Lazo, Cancer Res 1995 55 10 2021 2023 7743495
    • (1995) Cancer Res , vol.55 , Issue.10 , pp. 2021-2023
    • Kondo, Y.1    Woo, E.S.2    Michalska, A.E.3    Choo, K.H.4    Lazo, J.S.5
  • 57
    • 0032423811 scopus 로고    scopus 로고
    • Metallothionein and apoptosis in primary human hepatocellular carcinoma (HCC) from Northern China
    • Metallothionein and apoptosis in primary human hepatocellular carcinoma (HCC) from northern China. L Cai, GJ Wang, ZL Xu, DX Deng, S Chakrabarti, MG Cherian, Anticancer Res 1998 18 6B 4667 4672 9891538 (Pubitemid 29042041)
    • (1998) Anticancer Research , vol.18 , Issue.6 , pp. 4667-4672
    • Cai, L.1    Wang, G.J.2    Xu, Z.L.3    Deng, D.X.4    Chakrabarti, S.5    Cherian, M.G.6
  • 58
    • 0031954785 scopus 로고    scopus 로고
    • Metallothionein and apoptosis in primary human hepatocellular carcinoma and metastatic adenocarcinoma
    • DOI 10.1046/j.1365-2559.1998.00348.x
    • Metallothionein and apoptosis in primary human hepatocellular carcinoma and metastatic adenocarcinoma. DX Deng, S Chakrabarti, MP Waalkes, MG Cherian, Histopathology 1998 32 4 340 347 10.1046/j.1365-2559.1998.00348.x 9602331 (Pubitemid 28186593)
    • (1998) Histopathology , vol.32 , Issue.4 , pp. 340-347
    • Deng, D.X.1    Chakrabarti, S.2    Waalkes, M.P.3    Cherian, M.G.4
  • 59
    • 0027496641 scopus 로고
    • Metallothionein in testicular germ cell tumors and drug resistance: Clinical correlation
    • DOI 10.1002/1097-0142(19931115)72:10<3029::AID-CNCR2820721027>3.0. CO;2-6
    • Metallothionein in testicular germ cell tumors and drug resistance. Clinical correlation. JL Chin, D Banerjee, SA Kadhim, TE Kontozoglou, PJ Chauvin, MG Cherian, Cancer 1993 72 10 3029 3035 10.1002/1097-0142(19931115)72: 10<3029::AID-CNCR2820721027>3.0.CO;2-6 8221570 (Pubitemid 23335051)
    • (1993) Cancer , vol.72 , Issue.10 , pp. 3029-3035
    • Chin, J.L.1    Banerjee, D.2    Kadhim, S.A.3    Kontozoglou, T.E.4    Chauvin, P.J.5    Cherian, M.G.6
  • 60
    • 0037379323 scopus 로고    scopus 로고
    • Prognostic significance of metallothionein expression in correlation with Ki-67 expression in adenocarcinomas of large intestine
    • Prognostic significance of metallothionein expression in correlation with Ki-67 expression in adenocarcinomas of large intestine. P Dziegiel, J Forgacz, E Suder, P Surowiak, J Kornafel, M Zabel, Histol Histopathol 2003 18 2 401 407 12647790 (Pubitemid 36362057)
    • (2003) Histology and Histopathology , vol.18 , Issue.2 , pp. 401-407
    • Dziegiel, P.1    Forgacz, J.2    Suder, E.3    Surowiak, P.4    Kornafel, J.5    Zabel, M.6
  • 63
    • 1542329631 scopus 로고    scopus 로고
    • A p38 inhibitor allows to dissociate differentiation and apoptotic processes triggered upon LIF withdrawal in mouse embryonic stem cells
    • DOI 10.1038/sj.cdd.4401337
    • A p38 inhibitor allows to dissociate differentiation and apoptotic processes triggered upon LIF withdrawal in mouse embryonic stem cells. D Duval, M Malaise, B Reinhardt, C Kedinger, H Boeuf, Cell Death Differ. 2004 11 3 331 341 10.1038/sj.cdd.4401337 14685156 (Pubitemid 38313142)
    • (2004) Cell Death and Differentiation , vol.11 , Issue.3 , pp. 331-341
    • Duval, D.1    Malaise, M.2    Reinhardt, B.3    Kedinger, C.4    Boeuf, H.5
  • 64
    • 33644937423 scopus 로고    scopus 로고
    • Apoptosis and differentiation commitment: Novel insights revealed by gene profiling studies in mouse embryonic stem cells
    • 10.1038/sj.cdd.4401789 16311515
    • Apoptosis and differentiation commitment: novel insights revealed by gene profiling studies in mouse embryonic stem cells. D Duval, M Trouillas, C Thibault, D Dembele, F Diemunsch, B Reinhardt, et al. Cell Death Differ. 2006 13 4 564 575 10.1038/sj.cdd.4401789 16311515
    • (2006) Cell Death Differ. , vol.13 , Issue.4 , pp. 564-575
    • Duval, D.1    Trouillas, M.2    Thibault, C.3    Dembele, D.4    Diemunsch, F.5    Reinhardt, B.6
  • 65
    • 67349122760 scopus 로고    scopus 로고
    • Differential quantitative zinc-induced expression of human metallothionein isogenes in haematopoietic precursor cell lines
    • 10.1016/j.jtemb.2009.02.003 19398060
    • Differential quantitative zinc-induced expression of human metallothionein isogenes in haematopoietic precursor cell lines. P Maghdooni Bagheri, MT Rahman, S Van Soest, M De Ley, J Trace Elem Med Biol 2009 23 2 124 131 10.1016/j.jtemb.2009.02.003 19398060
    • (2009) J Trace Elem Med Biol , vol.23 , Issue.2 , pp. 124-131
    • Maghdooni Bagheri, P.1    Rahman, M.T.2    Van Soest, S.3    De Ley, M.4
  • 66
    • 0025363266 scopus 로고
    • Induced differentiation of K562 leukemia cells: A model for studies of gene expression in early megakaryoblasts
    • DOI 10.1016/0145-2126(90)90002-Q
    • Induced differentiation of K562 leukemia cells: a model for studies of gene expression in early megakaryoblasts. R Alitalo, Leuk Res 1990 14 6 501 514 10.1016/0145-2126(90)90002-Q 2197510 (Pubitemid 20213713)
    • (1990) Leukemia Research , vol.14 , Issue.6 , pp. 501-514
    • Alitalo, R.1
  • 67
    • 78649661603 scopus 로고    scopus 로고
    • Metallothionein in human immunomagnetically selected CD34(+) haematopoietic progenitor cells
    • 10.1042/CBI20090493 20828370
    • Metallothionein in human immunomagnetically selected CD34(+) haematopoietic progenitor cells. P Maghdooni Bagheri, M De Ley, Cell Biol Int 2011 35 1 39 44 10.1042/CBI20090493 20828370
    • (2011) Cell Biol Int , vol.35 , Issue.1 , pp. 39-44
    • Maghdooni Bagheri, P.1    De Ley, M.2
  • 68
    • 80052514000 scopus 로고    scopus 로고
    • Role of metallothionein in differentiation of leukemia cells
    • 10.1007/s11033-010-9967-7 20127519
    • Role of metallothionein in differentiation of leukemia cells. P Maghdooni Bagheri, I Govaerts, M De Ley, Mol Biol Rep 2011 38 5 3017 3022 10.1007/s11033-010-9967-7 20127519
    • (2011) Mol Biol Rep , vol.38 , Issue.5 , pp. 3017-3022
    • Maghdooni Bagheri, P.1    Govaerts, I.2    De Ley, M.3
  • 69
    • 0027232025 scopus 로고
    • Zinc metabolism and metallothionein expression in bone marrow during erythropoiesis
    • 8498498
    • Zinc metabolism and metallothionein expression in bone marrow during erythropoiesis. KL Huber, RJ Cousins, Am J Physiol 1993 264 5 Pt 1 770 E775 8498498
    • (1993) Am J Physiol , vol.264 , Issue.5 PART 1
    • Huber, K.L.1    Cousins, R.J.2
  • 70
    • 0141529770 scopus 로고    scopus 로고
    • Erythropoietin-induced metallothionein gene expression: Role in proliferation of K562 cells
    • Erythropoietin-induced metallothionein gene expression: role in proliferation of K562 cells. AB Abdel-Mageed, F Zhao, BJ Rider, KC Agrawal, Exp Biol Med (Maywood). 2003 228 9 1033 1039 (Pubitemid 37222172)
    • (2003) Experimental Biology and Medicine , vol.228 , Issue.9 , pp. 1033-1039
    • Abdel-Mageed, A.B.1    Zhao, F.2    Rider, B.J.3    Agrawal, K.C.4
  • 71
    • 0031811526 scopus 로고    scopus 로고
    • Metallothionein expression prevents apoptosis: A study with antisense phosphorothioate oligodeoxynucleotides in a human T cell line
    • Metallothionein expression prevents apoptosis: a study with antisense phosphorothioate oligodeoxynucleotides in a human T cell line. GT Tsangaris, F Tzortzatou-Stathopoulou, Anticancer Res 1998 18 4A 2423 2433 9703889 (Pubitemid 28386530)
    • (1998) Anticancer Research , vol.18 , Issue.4 , pp. 2423-2433
    • Tsangaris, G.Th.1    Tzortzatou-Stathopoulou, F.2
  • 72
    • 80052836966 scopus 로고    scopus 로고
    • Current findings for recurring mutations in acute myeloid leukemia
    • 10.1186/1756-8722-4-36 21917154
    • Current findings for recurring mutations in acute myeloid leukemia. S Takahashi, J Hematol Oncol. 2011 4 36 10.1186/1756-8722-4-36 21917154
    • (2011) J Hematol Oncol. , vol.4 , pp. 36
    • Takahashi, S.1
  • 73
    • 0028094436 scopus 로고
    • Expression of metallothionein in initial and relapsed childhood acute lymphoblastic leukemia
    • Expression of metallothionein in initial and relapsed childhood acute lymphoblastic leukemia. A Sauerbrey, F Zintl, M Volm, Ann Hematol 1994 69 3 111 115 10.1007/BF01695690 8086505 (Pubitemid 24284966)
    • (1994) Annals of Hematology , vol.69 , Issue.3 , pp. 111-115
    • Sauerbrey, A.1    Zintl, F.2    Volm, M.3
  • 74
    • 33645276010 scopus 로고    scopus 로고
    • Inverse correlation between Flt3 and PU.1 expression in acute myeloblastic leukemias
    • 10.1016/j.leukres.2005.07.015 16271760
    • Inverse correlation between Flt3 and PU.1 expression in acute myeloblastic leukemias. M Inomata, S Takahashi, H Harigae, J Kameoka, M Kaku, T Sasaki, Leuk Res 2006 30 6 659 664 10.1016/j.leukres.2005.07.015 16271760
    • (2006) Leuk Res , vol.30 , Issue.6 , pp. 659-664
    • Inomata, M.1    Takahashi, S.2    Harigae, H.3    Kameoka, J.4    Kaku, M.5    Sasaki, T.6
  • 77
    • 33745698763 scopus 로고    scopus 로고
    • Prognostic significance of PU.1 in follicular lymphoma
    • DOI 10.1002/path.1986
    • Prognostic significance of PU.1 in follicular lymphoma. EE Torlakovic, N Bilalovic, R Golouh, A Zidar, S Angel, J Pathol 2006 209 3 352 359 10.1002/path.1986 16639693 (Pubitemid 43997744)
    • (2006) Journal of Pathology , vol.209 , Issue.3 , pp. 352-359
    • Torlakovic, E.E.1    Bilalovic, N.2    Golouh, R.3    Zidar, A.4    Angel, S.5
  • 78
    • 0030747594 scopus 로고    scopus 로고
    • Metallothionein: A potential marker for differentiating benign and neoplastic gastrointestinal lymphoid infiltrates
    • DOI 10.1080/00313029700169764
    • Metallothionein: a potential marker for differentiating benign and neoplastic gastrointestinal lymphoid infiltrates. KS Rizkalla, MG Cherian, Pathology 1997 29 2 141 146 10.1080/00313029700169764 9213332 (Pubitemid 27296460)
    • (1997) Pathology , vol.29 , Issue.2 , pp. 141-146
    • Rizkalla, K.S.1    Cherian, M.G.2
  • 79
    • 33750731285 scopus 로고    scopus 로고
    • Pathobiology of classical Hodgkin lymphoma
    • DOI 10.1159/000095558
    • Pathobiology of classical Hodgkin lymphoma. A Tzankov, S Dirnhofer, Pathobiology 2006 73 3 107 125 10.1159/000095558 17085956 (Pubitemid 44699471)
    • (2006) Pathobiology , vol.73 , Issue.3 , pp. 107-125
    • Tzankov, A.1    Dirnhofer, S.2


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