Enhanced antitumor efficacy and decreased toxicity by self-associated docetaxel in phospholipid-based micelles

International Journal of Pharmaceutics

Volumn 434, Issue 1-2, 2012, Pages 413-419

  Tong, Shu Wen ^a   Xiang, Bai ^a   Dong, Da Wen ^a   Qi, Xian Rong ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Antitumor efficacy; Docetaxel (DTX); Micelle; Safety evaluation; Solubilization

Indexed keywords

DOCETAXEL; DRUG CARRIER; MACROGOL; METHOXY POLYETHYLENE GLYCOL DISTEAROYLPHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPID; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BIODEGRADABILITY; BREAST CANCER; CHEMICAL STRUCTURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG RELEASE; ENCAPSULATION; FEMALE; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VITRO STUDY; IN VIVO STUDY; MICELLE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; MICELLES; PARTICLE SIZE; PHOSPHATIDYLETHANOLAMINES; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; TAXOIDS;

EID: 84864149362     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.06.014     Document Type: Article

References (35)

1. B. Ashok, L. Arlefth, R.P. Hjelm, I. Rubinstein, and H. Önyüksel In vitro characterization of PEGylated phospholipid micelles for improved drug solubilization: effects of PEG chain length and PC incorporation J. Pharm. Sci. 93 2004 2476 2487
2. Y.H. Bae, and K. Park Targeted drug delivery to tumors: myths, reality and possibility J. Control. Release 153 2011 198 205
3. M.C. Bissery Preclinical pharmacology of docetaxel Eur. J. Cancer 31 1995 S1 S6
4. I. Brigger, C. Dubernet, and P. Couvreur Nanoparticles in cancer therapy and diagnosis Adv. Drug Deliv. Rev. 54 2002 631 651
5. H. Cesur, I. Rubinstein, A. Pai, and H. Onyüksel Self-associated indisulam in phospholipid-based nanomicelles: a potential nanomedicine for cancer Nanomedicine 5 2009 178 183
6. A. Domínguez, A. Fernández, N. González, E. Iglesias, and L. Montenegro Determination of critical micelle concentration of some surfactants by three techniques J. Chem. Educ. 74 1997 1227 1231
7. M. Elsabahy, M.E. Perron, N. Bertrand, G.E. Yu, and J.C. Leroux Solubilization of docetaxel in poly(ethylene oxide)-block-poly(butylene/styrene oxide) micelles Biomacromolecules 8 2007 2250 2257
8. A. Eschalier, J. Lavarenne, C. Burtin, M. Renoux, E. Chapuy, and M. Rodriguez Study of histamine release induced by acute administration of antitumor agents in dogs Cancer Chemother. Pharmacol. 21 1988 246 250
9. F. Fabbri, G. Brigliadori, S. Carloni, P. Ulivi, I. Vannini, A. Tesei, R. Silvestrini, D. Amadori, and W. Zoli Zoledronic acid increases docetaxel cytotoxicity through pMEK and Mcl-1 inhibition in a hormone-sensitive prostate carcinoma cell line J. Transl. Med. 6 2008 43
10. G. Gaucher, M.H. Dufresne, V.P. Sant, N. Kang, D. Maysinger, and J.C. Leroux Block copolymer micelles: preparation, characterization and application in drug delivery J. Control. Release 109 2005 169 188
11. K.K. Gill, A. Kaddoumi, and S. Nazzal Mixed micelles of PEG2000-DSPE and vitamin-E TPGS for concurrent delivery of paclitaxel and parthenolide: enhanced chemosenstization and antitumor efficacy against non-small cell lung cancer (NSCLC) cell lines Eur. J. Pharm. Sci. 2012 10.1016/j.ejps.2012.02.010
12. X. Han, J. Liu, M. Liu, C. Xie, C. Zhan, B. Gu, Y. Liu, L. Feng, and W. Lu 9-NC-loaded folate-conjugated polymer micelles as tumor targeted drug delivery system: preparation and evaluation in vitro Int. J. Pharm. 372 2009 125 131
13. M.A. Izquierdo, M. García, J.L. Pontón, M. Martínez, V. Valentí, M. Navarro, M. Gil, F. Cardenal, R. Mesía, X. Pérez, R. Salazar, and J.R. Germà-Lluch A phase I clinical and pharmacokinetic study of paclitaxel and docetaxel given in combination in patients with solid tumours Eur. J. Cancer 42 2006 1789 1796
14. A.S. Jakate, C.M. Einhaus, A.P. DeAnglis, G.S. Retzinger, and P.B. Desai Preparation, characterization, and preliminary application of fibrinogen-coated olive oil droplets for the targeted delivery of docetaxel to solid malignancies Cancer Res. 63 2003 7314 7320
15. M. Johnsson, P. Hansson, and K. Edwards Spherical micelles and other self-assembled structures in dilute aqueous mixtures of poly(ethylene glycol) lipids J. Phys. Chem. B 105 2001 8420 8430
16. M.C. Jones, and J.C. Leroux Polymeric micelles - a new generation of colloidal drug carriers Eur. J. Pharm. Biopharm 48 1999 101 111
17. K. Kawano, M. Watanabe, T. Yamamoto, M. Yokoyama, P. Opanasopit, T. Okano, and Y. Maitani Enhanced antitumor effect of camptothecin loaded in long-circulating polymeric micelles J. Control. Release 112 2006 329 332
18. U. Kedar, P. Phutane, S. Shidhaye, and V. Kadam Advances in polymeric micelles for drug delivery and tumor targeting Nanomedicine 6 2010 714 729
19. G.S. Kwon, and T. Okano Polymeric micelles as new drug carriers Adv. Drug Deliv. Rev. 21 1996 107 116
20. Y. Li, X.R. Qi, Y. Maitani, and T. Nagai PEG-PLA diblock copolymer micelle-like nanoparticles as all-trans-retinoic acid carrier: in vitro and in vivo characterizations Nanotechnology 20 2009 055106 (10 pp)
21. B. Liu, M. Yang, R. Li, Y. Ding, X. Qian, L. Yu, and X. Jiang The antitumor effect of novel docetaxel-loaded thermosensitive micelles Eur. J. Pharm. Biopharm. 69 2008 527 534
22. Y. Liu, K. Li, J. Pan, B. Liu, and S.S. Feng Folic acid conjugated nanoparticles of mixed lipid monolayer shell and biodegradable polymer core for targeted delivery of docetaxel Biomaterials 31 2010 330 338
23. A.N. Lukyanov, and V.P. Torchilin Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs Adv. Drug Deliv. Rev. 56 2004 1273 1289
24. C.F. Mu, P. Balakrishnan, F.D. Cui, Y.M. Yin, Y.B. Lee, H.G. Choi, C.S. Yong, S.J. Chung, C.K. Shim, and D.D. Kim The effects of mixed MPEG-PLA/Pluronic® copolymer micelles on the bioavailability and multidrug resistance of docetaxel Biomaterials 31 2010 2371 2379
25. Y. Ni, T. Cao, and P. Ma Study on antineoplastic activity and blood cell haemolysis test to saponin BMU J. 31 2008 85 90
26. P. Opanasopit, T. Ngawhirunpat, T. Rojanarata, C. Choochottiros, and S. Chirachanchai Camptothecin-incorporating N-phthaloylchitosan-g-mPEG self-assembly micellar system: effect of degree of deacetylation Colloids. Surf. B: Biointerfaces 60 2007 117 124
27. P.J. Photos, L. Bacakova, B. Discher, F.S. Bates, and D.E. Discher Polymer vesicles in vivo: correlations with PEG molecular weight J. Control. Release 90 2003 323 334
28. S. Samanta, and P. Ghosh Coalescence of bubbles and stability of foams in aqueous solutions of Tween surfactants Chem. Eng. Res. Des. 89 2011 2344 2355
29. Z. Sezgin, N. Yüksel, and T. Baykara Preparation and characterization of polymeric micelles for solubilization of poorly soluble anticancer drugs Eur. J. Pharm. Biopharm. 64 2006 261 268
30. D. Sutton, N. Nasongkla, E. Blanco, and J. Gao Functionalized micellar systems for cancer targeted drug delivery Pharm. Res. 24 2007 1029 1046
31. V.P. Torchilin Tumor delivery of macromolecular drugs based on the EPR effect Adv. Drug Deliv. Rev. 63 2011 131 135
32. V. Vichai, and K. Kirtikara Sulforhodamine B colorimetric assay for cytotoxicity screening Nat. Protoc. 1 2006 1112 1116
33. X. Wang, Y. Wang, X. Chen, J. Wang, X. Zhang, and Q. Zhang NGR-modified micelles enhance their interaction with CD13-overexpressing tumor and endothelial cells J. Control. Release 139 2009 56 62
34. Z. Weiszhár, J. Czúcz, C. Révész, L. Rosivall, J. Szebeni, and Z. Rozsnyay Complement activation by polyethoxylated pharmaceutical surfactants: Cremophor-EL, Tween-80 and Tween-20 Eur. J. Pharm. Sci. 45 2012 492 498
35. J.H. Zhao, B.D. Zhu, Q. Huang, P. Wang, and G.H. Qi Effects of sheng-Yu decoction on bone marrow, cell cycle and apoptosis of myelosuppressed mice Chin. J. Exp. Trad. Med. Formul. 17 2011 199 202