Identification and proteome analysis of the two-component VirR/VirS system in epidemic Streptococcus suis serotype 2

FEMS Microbiology Letters

Volumn 333, Issue 2, 2012, Pages 160-168

  Wang, Haihui ^a   Shen, Xiaodong ^a   Zhao, Yan ^a   Wang, Min ^a   Zhong, Qiu ^a   Chen, Tian ^a   Hu, Fuquan ^a   Li, Ming ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Knockout; Regulation; Streptococcus suis; Two component system; Virulence

Indexed keywords

BACTERIAL PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; BACTERIAL GENETICS; BACTERIAL MEMBRANE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CLOSTRIDIUM PERFRINGENS; CONTROLLED STUDY; EXPERIMENTAL MODEL; FUNCTIONAL PROTEOMICS; IN VITRO STUDY; IN VIVO STUDY; LETTER; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REGULATORY MECHANISM; STREPTOCOCCUS SUIS; TWO COMPONENT VIRR VIRS SYSTEM;

ANIMALS; BACTERIAL LOAD; BACTERIAL PROTEINS; CELL WALL; DISEASE MODELS, ANIMAL; GENE KNOCKOUT TECHNIQUES; MICE; MICE, INBRED BALB C; MICROBIAL VIABILITY; OXIDATIVE STRESS; PHENOTYPE; PROTEOME; REGULON; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS SUIS; SURVIVAL ANALYSIS; VIRULENCE FACTORS;

CLOSTRIDIUM PERFRINGENS; STREPTOCOCCUS SUIS; SUIDAE;

EID: 84864144167     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2012.02611.x     Document Type: Letter

References (37)

1. Bukau B & Horwich AL (1998) The Hsp70 and Hsp60 chaperone machines. Cell 92: 351-366.
2. Burall LS, Rodolakis A, Rekiki A, Myers GS & Bavoil PM (2009) Genomic analysis of an attenuated Chlamydia abortus live vaccine strain reveals defects in central metabolism and surface proteins. Infect Immun 77: 4161-4167.
3. Chao JD, Papavinasasundaram KG, Zheng X, Chavez-Steenbock A, Wang X, Lee GQ & Av-Gay Y (2010) Convergence of Ser/Thr and two-component signaling to coordinate expression of the dormancy regulon in Mycobacterium tuberculosis. J Biol Chem 285: 29239-29246.
4. Charland N, Harel J, Kobisch M, Lacasse S & Gottschalk M (1998) Streptococcus suis serotype 2 mutants deficient in capsular expression. Microbiology 144(Pt 2): 325-332.
5. Chen C, Tang J, Dong W et al. (2007) A glimpse of streptococcal toxic shock syndrome from comparative genomics of S. suis 2 chinese isolates. PLoS ONE 2: e315.
6. de Greeff A, Buys H, van Alphen L & Smith HE (2002) Response regulator important in pathogenesis of Streptococcus suis serotype 2. Microb Pathog 33: 185-192.
7. Esgleas M, Li Y, Hancock MA, Harel J, Dubreuil JD & Gottschalk M (2008) Isolation and characterization of alpha-enolase, a novel fibronectin-binding protein from Streptococcus suis. Microbiology 154: 2668-2679.
8. Feng Y, Pan X, Sun W et al. (2009) Streptococcus suis enolase functions as a protective antigen displayed on the bacterial cell surface. J Infect Dis 200: 1583-1592.
9. Hunsucker SA, Mitchell BS & Spychala J (2005) The 5′-nucleotidases as regulators of nucleotide and drug metabolism. Pharmacol Ther 107: 1-30.
10. Ibrahim YM, Kerr AR, Silva NA & Mitchell TJ (2005) Contribution of the ATP-dependent protease ClpCP to the autolysis and virulence of Streptococcus pneumoniae. Infect Immun 73: 730-740.
11. Jacques M, Gottschalk M, Foiry B & Higgins R (1990) Ultrastructural study of surface components of Streptococcus suis. J Bacteriol 172: 2833-2838.
12. Kajfasz JK, Martinez AR, Rivera-Ramos I, Abranches J, Koo H, Quivey RG Jr. & Lemos JA (2009) Role of Clp proteins in expression of virulence properties of Streptococcus mutans. J Bacteriol 191: 2060-2068.
13. Kiser KB & Lee JC (1998) Staphylococcus aureus cap5O and cap5P genes functionally complement mutations affecting enterobacterial common-antigen biosynthesis in Escherichia coli. J Bacteriol 180: 403-406.
14. Krell T, Lacal J, Busch A, Silva-Jimenez H, Guazzaroni ME & Ramos JL (2010) Bacterial sensor kinases: diversity in the recognition of environmental signals. Annu Rev Microbiol 64: 539-559.
15. Lal SK, Johnson S, Conway T & Kelley PM (1991) Characterization of a maize cDNA that complements an enolase-deficient mutant of Escherichia coli. Plant Mol Biol 16: 787-795.
16. Li M, Wang C, Feng Y et al. (2008) SalK/SalR, a two-component signal transduction system, is essential for full virulence of highly invasive Streptococcus suis serotype 2. PLoS ONE 3: e2080.
17. Li J, Tan C, Zhou Y et al. (2011) The two-component regulatory system CiaRH contributes to the virulence of Streptococcus suis 2. Vet Microbiol 148: 99-104.
18. Liang X, Chen YY, Ruiz T & Wu H (2011) New cell surface protein involved in biofilm formation by Streptococcus parasanguinis. Infect Immun 79: 3239-3248.
19. Liu GY, Doran KS, Lawrence T, Turkson N, Puliti M, Tissi L & Nizet V (2004) Sword and shield: linked group B streptococcal beta-hemolysin/cytolysin and carotenoid pigment function to subvert host phagocyte defense. P Natl Acad Sci USA 101: 14491-14496.
20. Lun ZR, Wang QP, Chen XG, Li AX & Zhu XQ (2007) Streptococcus suis: an emerging zoonotic pathogen. Lancet Infect Dis 7: 201-209.
21. Lyristis M, Bryant AE, Sloan J, Awad MM, Nisbet IT, Stevens DL & Rood JI (1994) Identification and molecular analysis of a locus that regulates extracellular toxin production in Clostridium perfringens. Mol Microbiol 12: 761-777.
22. Miles LA, Dahlberg CM, Plescia J, Felez J, Kato K & Plow EF (1991) Role of cell-surface lysines in plasminogen binding to cells: identification of alpha-enolase as a candidate plasminogen receptor. Biochemistry 30: 1682-1691.
23. Nakajima K, Hamanoue M, Takemoto N, Hattori T, Kato K & Kohsaka S (1994) Plasminogen binds specifically to alpha-enolase on rat neuronal plasma membrane. J Neurochem 63: 2048-2057.
24. Pan X, Ge J, Li M et al. (2009) The orphan response regulator CovR: a globally negative modulator of virulence in Streptococcus suis serotype 2. J Bacteriol 191: 2601-2612.
25. Peshavaria M & Day IN (1991) Molecular structure of the human muscle-specific enolase gene (ENO3). Biochem J 275(Pt 2): 427-433.
26. Ross PL, Huang YN, Marchese JN et al. (2004) Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Mol Cell Proteomics 3: 1154-1169.
27. Shimizu T, Ba-Thein W, Tamaki M & Hayashi H (1994) The virR gene, a member of a class of two-component response regulators, regulates the production of perfringolysin O, collagenase, and hemagglutinin in Clostridium perfringens. J Bacteriol 176: 1616-1623.
28. Shimizu T, Ohtani K, Hirakawa H et al. (2002) Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater. P Natl Acad Sci USA 99: 996-1001.
29. Smith HE, Damman M, van der Velde J, Wagenaar F, Wisselink HJ, Stockhofe-Zurwieden N & Smits MA (1999) Identification and characterization of the cps locus of Streptococcus suis serotype 2: the capsule protects against phagocytosis and is an important virulence factor. Infect Immun 67: 1750-1756.
30. Swartley JS, Liu LJ, Miller YK, Martin LE, Edupuganti S & Stephens DS (1998) Characterization of the gene cassette required for biosynthesis of the (alpha1->6)-linked N-acetyl-D-mannosamine-1-phosphate capsule of serogroup A Neisseria meningitidis. J Bacteriol 180: 1533-1539.
31. Takaya A, Tomoyasu T, Matsui H & Yamamoto T (2004) The DnaK/DnaJ chaperone machinery of Salmonella enterica serovar Typhimurium is essential for invasion of epithelial cells and survival within macrophages, leading to systemic infection. Infect Immun 72: 1364-1373.
32. Tang J, Wang C, Feng Y et al. (2006) Streptococcal toxic shock syndrome caused by Streptococcus suis serotype 2. PLoS Med 3: e151.
33. Tu le N, Jeong HY, Kwon HY, Ogunniyi AD, Paton JC, Pyo SN & Rhee DK (2007) Modulation of adherence, invasion, and tumor necrosis factor alpha secretion during the early stages of infection by Streptococcus pneumoniae ClpL. Infect Immun 75: 2996-3005.
34. Wu Z, Zhang W & Lu C (2008) Comparative proteome analysis of secreted proteins of Streptococcus suis serotype 9 isolates from diseased and healthy pigs. Microb Pathog 45: 159-166.
35. Yesilkaya H, Spissu F, Carvalho SM et al. (2009) Pyruvate formate lyase is required for pneumococcal fermentative metabolism and virulence. Infect Immun 77: 5418-5427.
36. Zhang A, Chen B, Mu X et al. (2009a) Identification and characterization of a novel protective antigen, Enolase of Streptococcus suis serotype 2. Vaccine 27: 1348-1353.
37. Zhang Q, Xu SX, Wang H et al. (2009b) Contribution of ClpE to virulence of Streptococcus pneumoniae. Can J Microbiol 55: 1187-1194.