Vaccination against encapsulated bacteria in hereditary C2 deficiency results in antibody response and opsonization due to antibody-dependent complement activation

Clinical Immunology

Volumn 144, Issue 3, 2012, Pages 214-227

  Jönsson, Göran ^a   Lood, Christian ^b   Gullstrand, Birgitta ^b   Holmström, Eva ^b   Selander, Barbro ^b   Braconier, Jean Henrik ^a   Sturfelt, Gunnar ^a   Bengtsson, Anders A ^a   Truedsson, Lennart ^b  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

C2 deficiency; Invasive infection; Opsonization; Phagocytosis; The complement system; Vaccination

Indexed keywords

HAEMOPHILUS INFLUENZAE TYPE B VACCINE; IMMUNOGLOBULIN G ANTIBODY; LECTIN; PNEUMO23; PNEUMOCOCCUS VACCINE; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ADOLESCENT; ADULT; ANTIBODY RESPONSE; ARTICLE; CHILD; CLINICAL ARTICLE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; FEMALE; FEVER; GRANULOCYTE; HAEMOPHILUS INFLUENZAE TYPE B; HUMAN; MALE; OPSONIZATION; PHAGOCYTOSIS; PNEUMOCOCCAL INFECTION; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SEROTYPE; SKIN REDNESS; SWELLING; VACCINATION;

ADOLESCENT; ADULT; ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODY FORMATION; BACTERIAL VACCINES; CHILD; CHILD, PRESCHOOL; COMPLEMENT ACTIVATION; COMPLEMENT C2; COMPLEMENT PATHWAY, ALTERNATIVE; COMPLEMENT PATHWAY, CLASSICAL; ERYTHROCYTES; FEMALE; GRANULOCYTES; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE TYPE B; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; OPSONIN PROTEINS; PHAGOCYTOSIS; PNEUMOCOCCAL INFECTIONS; SHEEP; STREPTOCOCCUS PNEUMONIAE; VACCINATION; YOUNG ADULT;

EID: 84864141220     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2012.06.008     Document Type: Article

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