Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris

Journal of Neurochemistry

Volumn 122, Issue 4, 2012, Pages 823-833

  Guha, Sonia ^a   Baltazar, Gabriel C ^a   Tu, Leigh Anne ^a   Liu, Ji ^a   Lim, Jason C ^a   Lu, Wennan ^a   Argall, Arthur ^a   Boesze Battaglia, Kathleen ^a   Laties, Alan M ^a   Mitchell, Claire H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

autophagy; dopamine; lipofuscin; lysosomal pH; retina

Indexed keywords

6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; CATHEPSIN D; CHLOROQUINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOPAMINE 1 RECEPTOR; DOPAMINE 5 RECEPTOR; DOPAMINE RECEPTOR; LIPOFUSCIN; LYSOSOME ENZYME; SMALL INTERFERING RNA; TAMOXIFEN;

ACIDIFICATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOFLUORESCENCE; ENZYME ACTIVATION; ENZYME ACTIVITY; LYSOSOME; MOUSE; NONHUMAN; PH; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; STARGARDT DISEASE;

MUS;

EID: 84864131118     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07804.x     Document Type: Article

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