EGFR signaling upregulates expression of microsomal prostaglandin e synthase-1 in cancer cells leading to enhanced tumorigenicity

Oncogene

Volumn 31, Issue 29, 2012, Pages 3457-3466

  Donnini, S ^a   Finetti, F ^a   Terzuoli, E ^a   Giachetti, A ^a   Iiguez M A ^b   Hanaka, H ^c   Fresno, M ^b   Radmark O ^c   Ziche, M ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

E cadherin; Egr 1; epidermal growth factor; mPGES 1; prostaglandinE 2; vimentin

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROSTAGLANDIN E2; PROSTAGLANDIN E2 SYNTHASE TYPE 1; PROSTAGLANDIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CARCINOGENESIS; CLONOGENIC ASSAY; CONTROLLED STUDY; DOWN REGULATION; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR GROWTH; UPREGULATION;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; EARLY GROWTH RESPONSE PROTEIN 1; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; FEMALE; GENE SILENCING; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; UP-REGULATION;

MUS;

EID: 84864130089     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.503     Document Type: Article

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