Molecular evolution of a-kinase anchoring protein (AKAP)-7: Implications in comparative PKA compartmentalization

BMC Evolutionary Biology

Volumn 12, Issue 1, 2012, Pages

  Johnson, Keven R ^a   Nicodemus Johnson, Jessie ^b   Carnegie, Graeme K ^a   Danziger, Robert S ^a,c  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c JESSE BROWN VA MEDICAL CENTER   (United States)

Author keywords

A Kinase anchoring protein; AKAP15 18; PKA compartmentalization; PKA regulatory subunit; Protein evolution

Indexed keywords

COMPARATIVE STUDY; ENZYME ACTIVITY; EVOLUTIONARY THEORY; GENE; PRIMATE; SITE CHARACTERIZATION; SPECIES OCCURRENCE; VERTEBRATE;

MUS; PRIMATES; RATTUS; RODENTIA; VERTEBRATA;

AKAP7 PROTEIN, HUMAN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; MEMBRANE PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; PHYLOGENY; PROTEIN DOMAIN; RAT; RNA SPLICING; SEQUENCE ALIGNMENT;

A KINASE ANCHOR PROTEINS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EVOLUTION, MOLECULAR; HUMANS; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN INTERACTION DOMAINS AND MOTIFS; RATS; RNA SPLICING; SEQUENCE ALIGNMENT;

EID: 84864129009     PISSN: None     EISSN: 14712148     Source Type: Journal    
DOI: 10.1186/1471-2148-12-125     Document Type: Article

References (61)

1. A novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane events. Fraser ID, et al. EMBO J 1998 17 8 2261 2272
2. AKAP15 anchors cAMP-dependent protein kinase to brain sodium channels. Tibbs VC, et al. J Biol Chem 1998 273 40 25783 25788
3. Spatial distribution of protein kinase A activity during cell migration is mediated by A-kinase anchoring protein AKAP Lbc. Paulucci-Holthauzen AA, et al. J Biol Chem 2009 284 9 5956 5967
4. A-kinase anchoring proteins and neuronal signaling mechanisms. Carnegie GK, Scott JD, Genes Dev 2003 17 13 1557 1568
5. Related protein-protein interaction modules present drastically different surface topographies despite a conserved helical platform. Banky P, et al. J Mol Biol 2003 330 5 1117 1129
6. The A-kinase anchoring domain of type IIalpha cAMP-dependent protein kinase is highly helical. Newlon MG, et al. J Biol Chem 1997 272 38 23637 23644
7. A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes. Newlon MG, et al. EMBO J 2001 20 7 1651 1662
8. AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes. Fink MA, et al. Circ Res 2001 88 3 291 297
9. AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex. Potet F, et al. Am J Physiol Heart Circ Physiol 2001 280 5 2038 H2045
10. Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes. Zaccolo M, Pozzan T, Science 2002 295 5560 1711 1715
11. AKAP-scaffolding proteins and regulation of cardiac physiology. Mauban JR, et al. Physiology (Bethesda) 2009 24 78 87
12. Dual specificity A-kinase anchoring proteins (AKAPs) contain an additional binding region that enhances targeting of protein kinase A type I. Jarnaess E, et al. J Biol Chem 2008 283 48 33708 33718
13. Single amino acids determine specificity of binding of protein kinase A regulatory subunits by protein kinase A anchoring proteins. Miki K, Eddy EM, J Biol Chem 1999 274 41 29057 29062
14. Molecular basis of AKAP specificity for PKA regulatory subunits. Gold MG, et al. Mol Cell 2006 24 3 383 395
15. A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase. Kinderman FS, et al. Mol Cell 2006 24 3 397 408
16. AKAPs: from structure to function. Colledge M, Scott JD, Trends Cell Biol 1999 9 6 216 221
17. AKAP79 and the evolution of the AKAP model. Dodge K, Scott JD, FEBS Lett 2000 476 1-2 58 61
18. Regulation of g protein-coupled receptor signaling by a-kinase anchoring proteins. Appert-Collin A, Baisamy L, Diviani D, J Recept Signal Transduct Res 2006 26 5-6 631 646
19. Adenylyl cyclase-A-kinase anchoring protein complexes: the next dimension in cAMP signaling. Dessauer CW, Mol Pharmacol 2009 76 5 935 941
20. Neuronal AKAP150 coordinates PKA and Epac-mediated PKB/Akt phosphorylation. Nijholt IM, et al. Cell Signal 2008 20 10 1715 1724
21. Compartmentalisation of phosphodiesterases and protein kinase A: opposites attract. Baillie GS, Scott JD, Houslay MD, FEBS Lett 2005 579 15 3264 3270
22. AKAP3 selectively binds PDE4A isoforms in bovine spermatozoa. Bajpai M, et al. Biol Reprod 2006 74 1 109 118
23. Regulation of neuronal PKA signaling through AKAP targeting dynamics. Dell'Acqua ML, et al. Eur J Cell Biol 2006 85 7 627 633
24. Functional modulation of GABAA receptors by cAMP-dependent protein phosphorylation. Moss SJ, et al. Science 1992 257 5070 661 665
25. Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neurons. Hall DD, et al. Biochemistry 2007 46 6 1635 1646
26. Loss of AKAP150 perturbs distinct neuronal processes in mice. Tunquist BJ, et al. Proc Natl Acad Sci U S A 2008 105 34 12557 12562
27. Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice. Soderling SH, et al. Proc Natl Acad Sci U S A 2003 100 4 1723 1728
28. Association of the type 1 protein phosphatase PP1 with the A-kinase anchoring protein AKAP220. Schillace RV, Scott JD, Curr Biol 1999 9 6 321 324
29. Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells. Henn V, et al. J Biol Chem 2004 279 25 26654 26665
30. Association of the type I regulatory subunit of cAMP-dependent protein kinase with cardiac myocyte sarcolemma. Robinson ML, et al. Arch Biochem Biophys 1996 330 1 181 187
31. The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways. Dodge-Kafka KL, et al. Nature 2005 437 7058 574 578
32. Regulatory actions of the A-kinase anchoring protein Yotiao on a heart potassium channel downstream of PKA phosphorylation. Kurokawa J, et al. Proc Natl Acad Sci U S A 2004 101 46 16374 16378
33. AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway. Carnegie GK, et al. Mol Cell 2008 32 2 169 179
34. The intermediate filament protein, synemin, is an AKAP in the heart. Russell MA, et al. Arch Biochem Biophys 2006 456 2 204 215
35. Identification and mapping of protein kinase A binding sites in the costameric protein myospryn. Reynolds JG, et al. Biochim Biophys Acta 2007 1773 6 891 902
36. Dopamine modulation of neuronal Na(+) channels requires binding of A kinase-anchoring protein 15 and PKA by a modified leucine zipper motif. Few WP, Scheuer T, Catterall WA, Proc Natl Acad Sci U S A 2007 104 12 5187 5192
37. Molecular mechanism of convergent regulation of brain Na(+) channels by protein kinase C and protein kinase A anchored to AKAP-15. Cantrell AR, et al. Mol Cell Neurosci 2002 21 1 63 80
38. AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum. Lygren B, et al. EMBO Rep 2007 8 11 1061 1067
39. A novel leucine zipper targets AKAP15 and cyclic AMP-dependent protein kinase to the C terminus of the skeletal muscle Ca2+ channel and modulates its function. Hulme JT, et al. J Biol Chem 2002 277 6 4079 4087
40. Beta-adrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15. Hulme JT, et al. Proc Natl Acad Sci U S A 2003 100 22 13093 13098
41. The A-kinase anchoring protein 15 regulates feedback inhibition of the epithelial Na+channel. Bengrine A, Li J, Awayda MS, FASEB J 2007 21 4 1189 1201
42. Regulation of ion channels by cAMP-dependent protein kinase and A-kinase anchoring proteins. Gray PC, Scott JD, Catterall WA, Curr Opin Neurobiol 1998 8 3 330 334
43. Supramolecular assemblies and localized regulation of voltage-gated ion channels. Dai S, Hall DD, Hell JW, Physiol Rev 2009 89 2 411 452
44. High-affinity AKAP7delta-protein kinase A interaction yields novel protein kinase A-anchoring disruptor peptides. Hundsrucker C, et al. Biochem J 2006 396 2 297 306
45. Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes. Christian F, et al. J Biol Chem 2011 286 11 9079 9096
46. Alternative splicing regulates the subcellular localization of A-kinase anchoring protein 18 isoforms. Trotter KW, et al. J Cell Biol 1999 147 7 1481 1492
47. AKAP7gamma is a nuclear RI-binding AKAP. Brown RL, et al. Biochem Biophys Res Commun 2003 306 2 394 401
48. Type II regulatory subunit (RII) of the cAMP-dependent protein kinase interaction with A-kinase anchor proteins requires isoleucines 3 and 5. Hausken ZE, et al. J Biol Chem 1994 269 39 24245 24251
49. Mutagenesis of the regulatory subunit (RII beta) of cAMP-dependent protein kinase II beta reveals hydrophobic amino acids that are essential for RII beta dimerization and/or anchoring RII beta to the cytoskeleton. Li Y, Rubin CS, J Biol Chem 1995 270 4 1935 1944
50. The potential use of AKAP18delta as a drug target in heart failure patients. Lygren B, Tasken KA, Expert Opin Biol Ther 2008 8 1099 1108
51. A-kinase anchoring proteins as potential drug targets. Tröger J, Moutty MC, Skroblin P, Klussmann E, Br J Pharmacol 2012 166 2 420 33 10.1111/j.1476-5381.2011.01796.x
52. Classification and phylogenetic analysis of the cAMP-dependent protein kinase regulatory subunit family. Canaves JM, Taylor SS, J Mol Evol 2002 54 1 17 29
53. The large isoforms of A-kinase anchoring protein 18 mediate the phosphorylation of inhibitor-1 by protein kinase A and the inhibition of protein phosphatase 1 activity. Singh A, et al. Mol Pharmacol 2011 79 3 533 40
54. AKAP 18 alpha and gamma have opposing effects on insulin release in INS-1E cells. Josefsen K, et al. FEBS Lett 2010 1 81 5
55. Identification of a 15-kDa cAMP-dependent protein kinase-anchoring protein associated with skeletal muscle L-type calcium channels. Gray PC, et al. J Biol Chem 1997 272 10 6297 302
56. Primary structure and function of an A kinase anchoring protein associated with calcium channels. Gray PC, et al. Neuron 1998 20 5 1017 26
57. Deletion of the distal C terminus of CaV1.2 channels leads to loss of beta-adrenergic regulation and heart failure in vivo. Fu Y, et al. J Biol Chem. 2011 286 14 12617 26
58. The Pfam protein families database. Finn RD, et al. Nucleic Acids Res 2008 38 Database issue) 211 22
59. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Tamura K, et al. Mol Biol Evol 2011 28 10 2731 9
60. Prediction of complete gene structures in human genomic DNA. Burge C, Karlin S, J Mol Biol 1997 268 1 78 94
61. Promoter2.0: for the recognition of PolII promoter sequences. Knudsen S, Bioinformatics 1999 15 5 356 61