Chemoprevention of familial adenomatous polyposis by bromo-noscapine (EM011) in the ApcMin/+ mouse model

International Journal of Cancer

Volumn 131, Issue 6, 2012, Pages 1435-1444

  Li, Shiwang ^a,b   Ghaleb, Amr M ^a   He, Jing ^a,b   Bughani, Usha ^a   Bialkowska, Agnieszka B ^a   Yang, Vincent W ^a   Joshi, Harish C ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

catenin; bromo noscapine; colon cancer; EM011; familial adenomatous polyposis; noscapine

Indexed keywords

ANTINEOPLASTIC AGENT; BETA CATENIN; BROMO NOSCAPINE; CASPASE 3; CYCLIN D1; EM 011; MYC PROTEIN; PROTEIN P21; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD TOXICITY; CANCER INHIBITION; CANCER PREVENTION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFICACY; EMBRYO; EMBRYONIC FIBROBLAST; ENZYME ACTIVATION; FAMILIAL COLON POLYPOSIS; FEMALE; FIBROBLAST; G2 PHASE CELL CYCLE CHECKPOINT; GENE DELETION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; MICROTUBULE; MITOSIS INHIBITION; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN INDUCTION; RNA INTERFERENCE; TREATMENT DURATION; TUMOR SUPPRESSOR GENE; TUMOR VOLUME;

ADENOMATOUS POLYPOSIS COLI; ANIMALS; ANTICARCINOGENIC AGENTS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BETA CATENIN; DIOXOLES; FEMALE; GENES, APC; HCT116 CELLS; HUMANS; ISOQUINOLINES; MICE; MICE, INBRED C57BL;

EID: 84864122581     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27344     Document Type: Article

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